GFRA4 Gene
protein-coding GIFtS: 51
GCID: GC20M003587
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GDNF family receptor alpha 4
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Aliases for GFRA4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| GDNF Family Receptor Alpha 41 2 | | GDNF Receptor Alpha-42 3 | | Persephin Receptor2 3 | | GDNF Family Receptor Alpha-42 | | GDNFR-Alpha-41 | | GFR Receptor Alpha 42 | | GFR-Alpha-41 | | |
Export aliases for GFRA4 gene to outside databasesPrevious GC identifers: GC20M003627 GC20M003634 |
Summaries for GFRA4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for GFRA4: The protein encoded by this gene is a member of the GDNF receptor family. It is aglycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RETtyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcriptvariants encoding different isoforms have been described for this gene. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: GFRA4_HUMAN, Q9GZZ7Function: Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Maybe important in C-cell development and, in the postnatal development of the adrenal medulla
|
Genomic Views for GFRA4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GFRA4 gene promoter: NRSF form 1 STAT5A NRSF form 2 LCR-F1 Egr-4 E47 C/EBPalpha CHOP-10 STAT3 ATF Other transcription factors
Search SABiosciences Chromatin IP Primers for GFRA4
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GFRA4 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13-p12 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13-p12GFRA4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M003587: view genomic region
(about GC identifiers)
Start:
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3,639,939 bp from pter |
End:
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3,644,046 bp from pter |
Size:
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4,108 bases |
Orientation:
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minus strand |
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Proteins for GFRA4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: GFRA4_HUMAN, Q9GZZ7 (See
protein sequence)Recommended Name: GDNF family receptor alpha-4 precursor Size: 299 amino acids; 31670 Da
Subcellular location: Isoform GFRalpha4a: Cell membrane; Lipid-anchor, GPI-anchor
Subcellular location: Isoform GFRalpha4b: Cell membrane; Lipid-anchor, GPI-anchor
Subcellular location: Isoform GFRalpha4c: Secreted
Secondary accessions: Q5JT74 Q9H191 Q9H192Alternative splicing: 3 isoforms: Q9GZZ7-1 Q9GZZ7-2 Q9GZZ7-3 Explore the universe of human proteins at neXtProt for GFRA4: NX_Q9GZZ7
GFRA4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_071422.1 NP_665705.1 ENSEMBL proteins: ENSP00000290417 ENSP00000313423 ENSP00000435801 Reactome Protein details: Q9GZZ7 Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
GFRA4 for ontologies About GeneDecksing
GFRA4 Antibody Products: Assay Products for GFRA4: |
Protein
Domains / Families for GFRA4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GFRA4 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9GZZ7ProtoNet protein and cluster: Q9GZZ7 UniProtKB/Swiss-Prot: GFRA4_HUMAN, Q9GZZ7Similarity: Belongs to the GDNFR family |
Function for GFRA4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: GFRA4_HUMAN, Q9GZZ7Function: Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Maybe important in C-cell development and, in the postnatal development of the adrenal medulla
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GFRA4 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GFRA4 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): GFRA4 (NM_022139) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GFRA4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GFRA4  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFRA4 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004872 | receptor activity |
-- | -- | | GO:0016167 | glial cell-derived neurotrophic factor receptor activity |
IEA | -- |
GFRA4 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for GFRA4: Animal Models: Mouse knock-out Gfra4tm1Msa for GFRA4 2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Gfra4):
GFRA4 for phenotypes About GeneDecksing
|
Pathways & Interactions for GFRA4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Development EGFR signaling pathway | | | 2 | NCAM signaling for neurite out-growth | | | 3 | Axon guidance | |
Pathway sources See GeneCards unified pathways Show all pathways
1 EMD Millipore Pathway for GFRA4 1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for GFRA4 1 GeneGo (Thomson Reuters) Pathway for GFRA4 4
Reactome Pathways for GFRA4
GFRA4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GFRA4
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
 1 Interacting protein for GFRA4 (Q9GZZ73 ENSP000003134234) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0030279 | negative regulation of ossification |
IEA | -- |
GFRA4 for ontologies About GeneDecksing
|
Drugs & Compounds for GFRA4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for GFRA4 Search CenterWatch for drugs/clinical trials and news about GFRA4 
|
Transcripts for GFRA4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for GFRA4 gene (3 alternative transcripts): NM_022139.3 NM_145762.2 NM_145763.1 Unigene Cluster for GFRA4: GDNF family receptor alpha 4 Hs.302025 Unigene Representative Sequence: NM_1457623 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000290417(uc002win.3 uc002wio.3) ENST00000319242(uc002wip.1) ENST00000477160
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GFRA4 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GFRA4 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): GFRA4 (NM_022139) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GFRA4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GFRA4  |
Additional cDNA sequence: AF253318.1 AJ291673.1 AJ291674.1 AJ291675.1 2 DOTS entries: DT.91653345 DT.91653343 7 AceView cDNA sequences: AJ291675 AJ291673 AJ291674 NM_145763 AF253318 NM_145762 NM_022139 GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for GFRA4 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | |
| SP1: | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for GFRA4
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Expression for GFRA4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GFRA4 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CTGGCAGAGT
About this image See GFRA4 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GFRA4
SOURCE GeneReport for Unigene cluster: Hs.302025 UniProtKB/Swiss-Prot: GFRA4_HUMAN, Q9GZZ7Tissue specificity: Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal andthyroid glands SABiosciences Custom PCR Arrays for GFRA4
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GFRA4 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GFRA4 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GFRA4 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GFRA4 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFRA4 |
Orthologs for GFRA4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for GFRA4 gene from 3/10 species (see all 10) About this table
ENSEMBL Gene Tree for GFRA4 (if available) TreeFam Gene Tree for GFRA4 (if available)  |
Paralogs for GFRA4 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for GFRA4 gene
- GFRA32 GFRA22 GFRAL2 GFRA12
1 SIMAP similar gene for GFRA4 using alignment to 1 protein entry: GFRA4_HUMAN:GFRA2
GFRA4 for paralogs About GeneDecksing
|
Genomic Variants for GFRA4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 20 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for GFRA4 (3639939 - 3644046 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for GFRA4: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GFRA4 |
|
Disorders
/ Diseases for GFRA4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GFRA4 for disorders About GeneDecksing
6 diseases for GFRA4: About MalaCardsmultiple endocrine neoplasia hirschsprung's disease thyroid carcinoma thyroiditis carcinoma neuronitis
1 Novoseek disease relationship for GFRA4 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| multiple endocrine neoplasia |
77.3 |
1 |
15592530 (1) |
Genetic Association Database (GAD): GFRA4 Human Genome Epidemiology (HuGE) Navigator: GFRA4 (1 document) Export disorders for GFRA4 gene to outside databases
|
Publications for GFRA4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GFRA4 gene, integrated from 9 sources (see all 12): (articles sorted by number of sources associating them with GFRA4) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Human glial cell line-derived neurotrophic factor receptor alpha4 is the receptor for persephin and is predomonantly expressed in normal and malignant thyroid medullary cells. (PubMed id 11116144)1, 2, 9 Lindahl M.... Saarma M. (2001)
- PSPN/GFRalpha4 has a significantly weaker capacity than GDNF/GFRalpha1 to recruit RET to rafts, but promotes neuronal survival and neurite outgrowth. (PubMed id 15225646)1, 3 Yang J....Saarma M. (2004)
- Investigation of germline GFRA4 mutations and evaluation of the involvement of GFRA1, GFRA2, GFRA3, and GFRA4 sequence variants in Hirschsprung disease. (PubMed id 12624147)1, 4 Borrego S....Eng C. (2003)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin. (PubMed id 10958791)1, 3 Masure S....Gordon R.D. (2000)
- hGFRalpha-4: a new member of the GDNF receptor family and a candidate for NBIA. (PubMed id 11551746)1 Zhou B....Gitschier J.M. (2001)
- GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin. (PubMed id 9740802)1 Enokido Y....Davies A.M. (1998)
- A model for GFR alpha 4 function and a potential modifying role in multiple endocrine neoplasia 2. (PubMed id 15592530)9 Vanhorne J.B....Mulligan L.M. (2005)
- GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family. (PubMed id 9576965)9 Baloh R.H.... Milbrandt J. (1998)
- Effect of neurturin on multipotent cells isolated from the adult skeletal muscle. (PubMed id 15896320)9 Vourc'h P....Chesselet M.F. (2005)
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External Searches for GFRA4 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing GFRA4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GFRA4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GFRA4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for GFRA4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for GFRA4 gene: Search GeneIP for patents involving GFRA4
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for GFRA4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for GFRA4 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GFRA4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GFRA4 | | OriGene Protein Over-expression Lysate for GFRA4 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for GFRA4 | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GFRA4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GFRA4 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for GFRA4 | | OriGene Custom Protein Services for GFRA4 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GFRA4 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GFRA4 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GFRA4 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GFRA4 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GFRA4 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GFRA4 |
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 |  |  |  | |
| | | Search Tocris compounds for GFRA4 |
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 | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFRA4 |
|  |  |  | | | Search ThermoFisher Antibodies for GFRA4 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GFRA4 |
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