Aliases for GFRA3 Gene
External Ids for GFRA3 Gene
Previous GeneCards Identifiers for GFRA3 Gene
The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. [provided by RefSeq, Jul 2008]
GeneCards Summary for GFRA3 Gene
GFRA3 (GDNF Family Receptor Alpha 3) is a Protein Coding gene. Among its related pathways are TGF-beta Signaling Pathway (sino) and GDNF-Family Ligands and Receptor Interactions. GO annotations related to this gene include receptor binding and axon guidance receptor activity. An important paralog of this gene is GFRA1.
UniProtKB/Swiss-Prot for GFRA3 Gene
Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.