GFRA2 Gene
protein-coding GIFtS : 61 GCID: GC08 M021593
GDNF family receptor alpha 2
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Aliasesfor GFRA2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases GDNF Family Receptor Alpha 2 1 2 TGF-Beta-Related Neurotrophic Factor Receptor 22 3 GDNFRB1 2 3 5 NRTNR-ALPHA2 RETL21 2 3 GDNF Family Receptor Alpha-22 TRNR21 2 3 GFR-Alpha 22 NTNRA1 2 Glial Cell Line Derived Neurotrophic Factor Receptor, Beta2 Neurturin Receptor Alpha2 3 PI-Linked Cell-Surface Accessory Protein2 GDNFR-Alpha-21 TRN Receptor, GPI-Anchored2 GDNFR-Beta1 GFR-Alpha-21 NTNR-Alpha1 NRTNR-Alpha1 GDNF Receptor Beta2 3 GDNF Receptor Alpha-23 RET Ligand 22 3
Export aliases for GFRA2 gene to outside databases Previous GC identifers: GC08M021338 GC08M021863 GC08M021559 GC08M020092
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Summariesfor GFRA2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for GFRA2 : Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Sep 2009) UniProtKB/Swiss-Prot: GFRA2_HUMAN, O00451 Function : Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor.Also able to mediate GDNF signaling through the RET tyrosine kinase receptor Gene Wiki entry for GFRA2
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Genomic Viewsfor GFRA2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000008.10 NC_018919.1 NT_167187.1 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GFRA2 gene promoter:RP58 Tal-1 MAZR Olf-1 CUTL1 E47 GATA-2 CREB MZF-1 STAT3 Other transcription factors Search SABiosciences Chromatin IP Primers for GFRA2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 8p21.3 Ensembl cytogenetic band: 8p21.3 HGNC cytogenetic band: 8p21.3 GFRA2 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 8 GeneLoc Exon Structure
GeneLoc location for GC08M021593: view genomic region
(about GC identifiers )
Start: 21,547,915 bp from pter End:
21,669,869 bp from pter
Size: 121,955 bases Orientation:
minus strand
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Proteinsfor GFRA2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: GFRA2_HUMAN, O00451 See
protein sequence )Recommended Name: Size : 464 amino acids; 51544 DaSubcellular location : Cell membrane; Lipid-anchor, GPI-anchor (By similarity)Secondary accessions : E9PD47 O15316 O15328 Q58J92 Q6GTR9 Q7Z5C2Alternative splicing : 3 isoforms : O00451-1 O00451-2 O00451-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for GFRA2: NX_O00451 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_O00451 GFRA2 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins (3 alternative transcripts): NP_001158510.1 NP_001158511.1 NP_001486.4 ENSEMBL proteins: ENSP00000428518 ENSP00000306654 ENSP00000429445 ENSP00000429206 ENSP00000429979 ENSP00000428721 ENSP00000428649 ENSP00000430622 ENSP00000383592 Reactome Protein details: O00451 Human Recombinant Protein Products for GFRA2: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing GFRA2 Antibody Products: Assay Products for GFRA2:
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Protein
Domains /for GFRA2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry O00451 ProtoNet protein and cluster: O00451
2 Blocks protein families : IPB003438 IPB003504 UniProtKB/Swiss-Prot: GFRA2_HUMAN, O00451 Similarity : Belongs to the GDNFR family
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Functionfor GFRA2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: GFRA2_HUMAN, O00451 Function : Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor.Also able to mediate GDNF signaling through the RET tyrosine kinase receptor
Genatlas biochemistry entry for GFRA2 glial cell line-derived neurotrophic factor (GDNF) receptor alpha 2,47kDa,mediating the autophosphorylation of RET,abundantly expressed in adult brain,intestine,placenta,fetal brain,lung,kidney,also receptor for neurturin and TGF-beta-related neurotrophic factor Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0004872 receptor activity
-- -- GO:0016167 glial cell-derived neurotrophic factor receptor activity
TAS 10829012
About GeneDecksing Phenotypes: 8 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Gfra2) :About GeneDecksing Animal Models: Gfra2 tm1Msa for GFRA2Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 5 )human mouse rat see all 3 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): GFRA2 (NM_001495 ) Sino Biological Human cDNA Clone for GFRA2 DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GFRA2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat GFRA2
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFRA2
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Pathways & Interactionsfor GFRA2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways About this table See pathways by source Super-pathway contained gene-specific pathways 1 Development EGFR signaling pathway 2 NCAM signaling for neurite out-growth 3 Axon guidance
Pathway sources See GeneCards unified pathways Show all pathways 1 1 1 4 About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GFRA2 STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)3 Interacting proteins for GFRA2 (O00451 3 ENSP00000306654 4 via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 3 biological process terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
TAS 9192898 GO:0007399 nervous system development
IEA -- GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway
TAS 10829012
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Drugs & Compoundsfor GFRA2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Browse Tocris compounds for GFRA2 2 Novoseek chemical compound relationships for GFRA2 gene About this table GFRA2
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Transcriptsfor GFRA2 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for GFRA2 gene (3 alternative transcripts): NM_001165038.1 NM_001165039.1 NM_001495.4 Unigene Cluster for GFRA2:
GDNF family receptor alpha 2 Hs.441202 [show with all ESTs ] Unigene Representative Sequence: BC041688 10 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000524240 ENST00000306793 (uc003wzu.1 ) ENST00000517328 ENST00000518077 ENST00000517892 ENST00000522071 ENST00000520826 ENST00000519195 ENST00000520676 ENST00000400782 (uc003wzv.1 uc003wzw.1 ) Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 5 )human mouse rat see all 3 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): GFRA2 (NM_001495 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GFRA2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat GFRA2
Additional cDNA sequence: AF002700.1 AK299623.1 AY326396.1 AY941828.1 BC041688.1 U93703.1 U97145.1
5 DOTS entries : DT.454929 DT.121481372
DT.100663400 DT.100704878 DT.97823407 21 AceView cDNA sequences :
BX426023 BX447443 CA393138 CB994592 AL530976 BX440579 BG718419 CA392962 CB996522 BX425245 BM805557 BM011391 BX485872 BU501708 BQ889433 AL545236 AL552892 BX446824 BM013065 BX333936 BQ068514 GeneLoc Exon Structure 4 Alternative Splicing Database (ASD) splice patterns (SP) for GFRA2 About this scheme ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b SP1 : SP2 : - SP3 : - - SP4 : -
ECgene alternative splicing isoforms for GFRA2
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Expression for GFRA2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GFRA2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TGCTTCACAGAbout this image GFRA2 expression in embryonic tissues and stem cells About this table
See GFRA2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GFRA2 SOURCE GeneReport for Unigene cluster: Hs.441202 UniProtKB/Swiss-Prot: GFRA2_HUMAN, O00451 Tissue specificity : Isoform 1 is found in both brain and placentaSABiosciences Expression via Pathway-Focused PCR Arrays including GFRA2 : Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFRA2
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Orthologsfor GFRA2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for GFRA2 gene from 2/10 species (see all 10 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves GFRA21
GDNF family receptor alpha 2
76.62(n) 76.19(a)
395993 NM_205101.1 NP_990432.1
zebrafish Actinopterygii LOC5649161
GDNF family receptor alpha-2-like
63.76(n) 64.64(a)
564916 XM_688234.4 XP_693326.4
ENSEMBL Gene Tree for GFRA2 (if available)TreeFam Gene Tree for GFRA2 (if available)
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Paralogsfor GFRA2 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for GFRA2 gene GFRA3 2 GFRAL 2 GFRA1 2 GFRA4 2 3 SIMAP similar genes for GFRA2 using alignment to 5 protein entries: GFRA2_HUMAN (see all proteins ):GFRA1 GFRA3 GFRA4 About GeneDecksing
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Genomic Variantsfor GFRA2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 8 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for GFRA2 (21547915 - 21669869 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for GFRA2 2 CNVs 65081 3726
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor GFRA2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 601956
OMIM disorders : --16 : About MalaCards geniculate ganglionitis tardive dyskinesia hirschsprung's disease retinal degeneration neuronitis paraganglioma teratocarcinoma retinitis pheochromocytoma thyroiditis polyposis thyroid carcinoma thyroid cancer schizophrenia carcinoma alzheimer's disease 3 Novoseek disease relationships for GFRA2 gene About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
hirschsprung disease
40.6
1
11409869 (1)
retinal degeneration
37.9
2
11239244 (2)
tumors
0
2
10822229 (1)
Genetic Association Database (GAD): GFRA2 Human Genome Epidemiology (HuGE) Navigator: GFRA2 (8 documents) Export disorders for GFRA2 gene to outside databases
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Publicationsfor GFRA2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for GFRA2 gene, integrated from 9 sources (see all 63 ):(articles sorted by number of sources associating them with GFRA2) Utopia : connect your pdf to the dynamic
Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins. (PubMed id 9177201) 1 , 2 , 3, 9(1997) Cloning, mRNA distribution and chromosomal localisation of the gene for glial cell line-derived neurotrophic factor receptor beta, a homologue to GDNFR-alpha. (PubMed id 9259272) 1 , 2 , 9(1997) TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. (PubMed id 9182803) 1 , 2 , 9(1997) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) Investigation of germline GFRA4 mutations and evaluation of the involvement of GFRA1, GFRA2, GFRA3, and GFRA4 sequence variants in Hirschsprung disease. (PubMed id 12624147) 1 , 4(2003) Evaluation of germline sequence variants of GFRA1, GFRA2, and GFRA3 genes in a cohort of Spanish patients with sporadic medullary thyroid cancer. (PubMed id 12490080) 1 , 4(2002) Cloning and characterization of the human GFRA2 locus and investigation of the gene in Hirschsprung disease. (PubMed id 11409869) 1 , 9(2001) GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family. (PubMed id 9407096) 1 , 9(1997) A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. (PubMed id 9192898) 1 , 9(1997) Glial cell line-derived neurotrophic factor receptor alpha 2 (GFRA2) gene is associated with tardive dyskinesia. (PubMed id 20369355) 1 , 9(2010)
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External Searches for GFRA2 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing GFRA2 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing GFRA2 gene
(According to HUGE )
About This Section --
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Specialized Databases showing GFRA2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for GFRA2 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for GFRA2 gene: GFRA2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor GFRA2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
OriGene Antibodies for GFRA2 OriGene shRNA RFP for GFRA2 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat OriGene Protein Over-expression Lysate for GFRA2 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for GFRA2 OriGene 3'-UTR Clone for GFRA2 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for GFRA2 OriGene Custom Protein Services for GFRA2 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GFRA2 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for GFRA2
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFRA2
ThermoFisher Antibodies for GFRA2
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat GFRA2
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Browse Tocris compounds for 
Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
