GFER Gene
protein-coding GIFtS: 60
GCID: GC16P002083
|
|
growth factor, augmenter of liver regeneration(Previous names: growth factor, erv1 (S. cerevisiae)-like (augmenter of...)
| |
Aliases
for GFER gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Growth Factor, Augmenter Of Liver Regeneration1 2 | | ERV1 Homolog2 | | ALR1 2 3 5 | | Erv1-Like Growth Factor2 | | HERV11 2 3 | | FAD-Linked Sulfhydryl Oxidase ALR2 | | ERV11 2 5 | | Hepatic Regenerative Stimulation Substance2 | | HPO11 2 | | Hepatopoietin Protein2 | | HPO21 2 | | EC 1.8.3.23 | | HSS1 2 | | Hepatopoietin3 | | HPO2 3 | | Augmenter Of Liver Regeneration3 | | Growth Factor, Erv1 (S. Cerevisiae)-Like (Augmenter Of Liver Regeneration)1 | | HERV11 2 3 |
Export aliases for GFER gene to outside databasesPrevious GC identifers: GC16P002051 GC16P002061 GC16P001974 GC16P002036 GC16P001965 GC16P002043 GC16P002045 GC16P002049 GC16P002056 |
Summaries
for GFER gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for GFER:
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factorsresponsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepaticregenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus forpolycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeastscERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes,and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ALR_HUMAN, P55789Function: Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds inCHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrialintermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge withGFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomesre-oxidized by donating electrons to cytochrome c or molecular oxygenFunction: Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regeneration
Gene Wiki entry for GFER
|
Genomic Views
for GFER gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the GFER gene promoter:
ER-alpha p53 ATF-2 AP-4 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for GFER
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GFER |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3-p13.12 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3-p13.12GFER Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P002083: view genomic region
(about GC identifiers)
Start:
|
2,034,150 bp from pter |
End:
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2,037,750 bp from pter |
Size:
|
3,601 bases |
Orientation:
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plus strand |
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Proteins
for GFER gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ALR_HUMAN, P55789 (See
protein sequence)Recommended Name: FAD-linked sulfhydryl oxidase ALR Size: 205 amino acids; 23449 Da
Cofactor: FAD
Subunit: Homodimer; disulfide-linked. May form heterodimers of isoform 1 and isoform 2
Subcellular location: Isoform 1: Mitochondrion intermembrane space
Subcellular location: Isoform 2: Cytoplasm. Secreted
Sequence caution: Sequence=AAA96390.2; Type=Frameshift; Positions=70; Sequence=AAD36986.1; Type=Erroneous initiation;Note=Translation N-terminally extended; Sequence=AAD56538.1; Type=Erroneous initiation; Note=Translation N-terminallyextended; Sequence=AAH02429.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH28348.2;Type=Erroneous initiation; Note=Translation N-terminally extended;
6 PDB 3D structures from  and Proteopedia  for GFER:3MBG (3D)
3O55 (3D)
3TK0 (3D)
3U2L (3D)
3U2M (3D)
3U5S (3D)
Secondary accessions: Q53YM6 Q8TAH6 Q9H290 Q9UK40Alternative splicing: 2 isoforms: P55789-1 P55789-2 Explore the universe of human proteins at neXtProt for GFER: NX_P55789
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P55789
GFER Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005253.3
ENSEMBL proteins: ENSP00000456432 ENSP00000248114 ENSP00000456189 ENSP00000455885 Reactome Protein details: P55789
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
GFER for ontologies About GeneDecksing
GFER Antibody Products:
Assay Products for GFER: |
Protein
Domains /
Families
for GFER gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GFER for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P55789ProtoNet protein and cluster: P55789 1 Blocks protein family: IPB006863 Erv1/Alr
UniProtKB/Swiss-Prot: ALR_HUMAN, P55789Similarity: Contains 1 ERV/ALR sulfhydryl oxidase domain |
Function
for GFER gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ALR_HUMAN, P55789Function: Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds inCHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrialintermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge withGFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomesre-oxidized by donating electrons to cytochrome c or molecular oxygenFunction: Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regenerationCatalytic activity: 2 R'C(R)SH + O(2) = R'C(R)S-S(R)CR' + H(2)O(2) Genatlas biochemistry entry for GFER:growth factor homolog of yeast ERV1 gene,15.1kDa, (?involved in oxidative phosphorylation),identical to SazB/C locus(see D16S530E)
Enzyme Number (IUBMB): EC 1.8.3.21
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GFER (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GFER (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: GFER (NM_005262) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GFER | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GFER |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFER |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
GFER for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for GFER:
|
Pathways & Interactions
for GFER gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/14 super-pathways (see all 14) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptotic Pathways in Synovial Fibroblasts | | | 2 | GPCR Pathway | | | 3 | Rho Family GTPases | | | 4 | TGF-Beta Pathway | | | 5 | Nanog in Mammalian ESC Pluripotency | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/54 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GFER (see all 54)
2 
Reactome Pathways for GFER
GFER for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GFER
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/37 Interacting proteins for GFER (P557892, 3 ENSP000002481144) via UniProtKB, MINT, STRING, and/or I2D (see all 37)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006626 | protein targeting to mitochondrion |
TAS | -- | | GO:0007283 | spermatogenesis |
NAS | -- | | GO:0008283 | cell proliferation |
NAS | -- | | GO:0044267 | cellular protein metabolic process |
TAS | -- |
GFER for ontologies About GeneDecksing
|
Drugs & Compounds
for GFER gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
GFER for compounds About GeneDecksing
 Browse Tocris compounds for GFER
1 HMDB Compound for GFER About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| FAD | 1H-Purin-6-amine flavin dinucleotide (see all 21) | 146-14-5 | -- |
1 DrugBank Compound for GFER About this table
1 Novoseek chemical compound relationship for GFER gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| cysteine |
3.8 |
2 |
15683237 (1), 14500725 (1) |
Search CenterWatch for drugs/clinical trials and news about GFER / ALR
|
Transcripts
for GFER gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for GFER gene: NM_005262.2 Unigene Cluster for GFER: Growth factor, augmenter of liver regeneration Hs.744156 [show with all ESTs]Unigene Representative Sequence: NM_0052625 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000569451 ENST00000248114(uc002cob.3 uc002coc.3) ENST00000561710
ENST00000565658 ENST00000567719
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GFER (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GFER (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: GFER (NM_005262) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GFER | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GFER |
Additional cDNA sequence: AF124603.1 AF124604.1 AF208342.1 AF306863.1 AY550027.1 BC002429.1 BC028348.2 U31176.1 6 DOTS entries: DT.446584 DT.75111124 DT.120657401 DT.100667953 DT.95320427 DT.95273315 24/96 AceView cDNA sequences (see all 96): BM699603 BM701668 BX283260 AW451842 AY550027 BU634006 BM712141 CK819931 CR616739 AI951959 BM696090 CA440890 BM141862 BM664375 BC028348 BM141857 CA314925 BU624003 AF124603 BM142163 BU622978 BM823891 BU734265 AW024944
GeneLoc Exon Structure
|
Expression
for GFER gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GFER expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTGGATAGG
About this image
See GFER Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GFER
SOURCE GeneReport for Unigene cluster: Hs.744156
UniProtKB/Swiss-Prot: ALR_HUMAN, P55789Tissue specificity: Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle
SABiosciences Custom PCR Arrays for GFER
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GFER
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GFER | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GFER | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GFER | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFER |
Orthologs
for GFER gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for GFER gene from 10/30 species (see all 30) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Gfer1 , 5 |
growth factor, erv1 (S. cerevisiae)-like (augmenter more1, 5 |
81.56(n)1
78.17(a)1 |
|
17 (12.48 cM)5
116921 NM_023040.31 NP_075527.21
246931915 |
chicken
(Gallus gallus) |
Aves |
GFER1 |
growth factor, augmenter of liver regeneration |
63.92(n)
60(a) |
|
416547 XM_414848.3 XP_414848.2 |
lizard
(Anolis carolinensis) |
Reptilia |
GFER6 |
-- |
54(a) |
1 ↔ 1 |
GL343650.1(143221-146882) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.110362 |
Xenopus laevis transcribed sequence with moderate similarity more |
75.6(n) |
|
CA981864.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
gfer1 |
growth factor, augmenter of liver regeneration (ERV1 more |
62.24(n)
58.86(a) |
|
560433 NM_001089386.1 NP_001082855.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG125343
Alr1 |
flavin-linked sulfhydryl oxidase3
Augmenter of liver regeneration1 |
52(a)3
59.26(n)1
51.11(a)1 |
|
18F13
329911 NM_134509.21 NP_608353.21 |
worm
(Caenorhabditis elegans) |
Secernentea |
F56C11.31 , 3 |
Protein F56C11.31 |
52(a)3
52.55(n)1
48.18(a)1 |
|
I(182139-182771)3
1716111 NM_058289.31 NP_490690.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
ERV11 |
Erv1p |
52.85(n)
46.85(a) |
|
852916 NP_011543.4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
Erv16 |
Erv1/Alr-like protein |
26(a) |
1 ↔ 1 |
1(18464017-18466077) |
rice
(Oryza sativa) |
Liliopsida |
-- |
FAD-linked sulfhydryl oxidase ALR, putative, expre... |
28(a) |
1 ↔ 1 |
3(5572283-5575434) |
ENSEMBL Gene Tree for GFER (if available)
TreeFam Gene Tree for GFER (if available) |
Paralogs
for GFER gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for GFER gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for GFER (2034150 - 2037750 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for GFER
5 CNVs: 53306 29657 5329 30001 29656
Human Gene Mutation Database (HGMD): GFER
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GFER |
|
Disorders
/ Diseases
for GFER gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GFER for disorders About GeneDecksing
OMIM gene information: 600924
OMIM disorders: 613076
UniProtKB/Swiss-Prot: ALR_HUMAN, P55789
Defects in GFER are a cause of mitochondrial progressive myopathy with congenital cataract hearing loss anddevelopmental delay (MPMCHD) [MIM:613076]; also called combined mitochondrial complex deficiency
20/23  diseases for GFER (see all 23): About MalaCardsmyopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay polycystic kidney disease hepatitis kidney disease
nodular regenerative hyperplasia congenital cataracts cataract myopathy
viral hepatitis liver cirrhosis hepatoblastoma hepatocellular carcinoma
t-cell leukemia twinning leukemia neuroblastoma
tuberculosis carcinoma malaria mycobacterium tuberculosis
1 Novoseek disease relationship for GFER gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
1 |
12713870 (1) |
Human Genome Epidemiology (HuGE) Navigator: GFER (1 document)
Export disorders for GFER gene to outside databases
|
Publications
for GFER gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GFER gene, integrated from 9 sources (see all 77):
(articles sorted by number of sources associating them with GFER) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A new human gene located in the PKD1 region of chromosome 16 is a functional homologue to ERV1 of yeast. (PubMed id 8575761)1, 2, 3 Lisowsky T....Schneider M.C. (1995)
- Identification of hepatopoietin dimerization, its interacting regions and alternative splicing of its transcription. (PubMed id 12180965)1, 2, 9 Li Y....He F. (2002)
- The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency. (PubMed id 19409522)1, 2, 9 Di Fonzo A....Comi G.P. (2009)
- An electron-transfer path through an extended disulfid e relay system: the case of the redox protein ALR. (PubMed id 22224850)1, 2 Banci L....Tokatlidis K. (2012)
- Molecular recognition and substrate mimicry drive the electron- transfer process between MIA40 and ALR. (PubMed id 21383138)1, 2 Banci L.... Tokatlidis K. (2011)
- Structure of the human sulfhydryl oxidase augmenter o f liver regeneration and characterization of a human mutation causing an autoso mal recessive myopathy . (PubMed id 20593814)1, 2 Daithankar V.N....Thorpe C. (2010)
- Augmenter of liver regeneration: substrate specificit y of a flavin-dependent oxidoreductase from the mitochondrial intermembrane spa ce. (PubMed id 19397338)1, 2 Daithankar V.N....Thorpe C. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Stimulation of the mitogen-activated protein kinase cascade and tyrosine phosphorylation of the epidermal growth factor receptor by hepatopoietin. (PubMed id 10982794)1, 9 Li Y....He F. (2000)
- The potentiation role of hepatopoietin on activator protein-1 is dependent on its sulfhydryl oxidase activity. (PubMed id 14500725)1, 9 Chen X....He F. (2003)
|
External Searches for GFER gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing GFER gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GFER gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GFER gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for GFER | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for GFER gene:
Search GeneIP for patents involving GFER
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for GFER gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for GFER | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GFER | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GFER | | | OriGene Protein Over-expression Lysate for GFER | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for GFER | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GFER | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GFER | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for GFER | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for GFER | | OriGene Custom Protein Services for GFER | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GFER | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GFER | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GFER | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GFER | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GFER | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GFER |
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| | | | Search Tocris compounds for GFER |
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 | | | GFER Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GFER |
|  |  |  | | | | Search ThermoFisher Antibodies for GFER |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GFER |
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