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GET4 Gene

protein-coding   GIFtS: 48
GCID: GC07P000916

Golgi To ER Traffic Protein 4 Homolog (S. Cerevisiae)

(Previous name: chromosome 7 open reading frame 20)
(Previous symbol: C7orf20)
  See GET4-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Golgi To ER Traffic Protein 4 Homolog (S. Cerevisiae)1 2     CGI-20 Protein1
C7orf201 2 3 5     Chromosome 7 Open Reading Frame 201
CEE2 3 5     Transmembrane Domain Recognition Complex1
Conserved Edge Protein1 2     H_NH1244M04.52
Conserved Edge-Expressed Protein2 3     Conserved Edge Expressed Protein2
Transmembrane Domain Recognition Complex 35 KDa Subunit2 3     Golgi To ER Traffic Protein 4 Homolog2
TRC352 3     Transmembrane Domain Recognition Complex, 35kDa2
35kDa1     

External Ids:    HGNC: 216901   Entrez Gene: 516082   Ensembl: ENSG000002398577   OMIM: 6120565   UniProtKB: Q7L5D63   

Export aliases for GET4 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for GET4 Gene:
GET4 (golgi to ER traffic protein 4 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with GET4 include erysipeloid, and louping ill.

UniProtKB/Swiss-Prot: GET4_HUMAN, Q7L5D6
Function: Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of
tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type
II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA
proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the
transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting

Gene Wiki entry for GET4 (C7orf20) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NC_018918.2  NT_007819.18  
Regulatory elements:
   Search for regulatory transcription factor binding sites for GET4
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): GET4 promoter sequence
   Search Chromatin IP Primers for GET4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GET4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.3   Ensembl cytogenetic band:  7p22.3   HGNC cytogenetic band: 7p22.3

GET4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GET4 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P000916:  view genomic region     (about GC identifiers)

Start:
916,189 bp from pter      End:
936,073 bp from pter
Size:
19,885 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 971,141-990,596     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: GET4_HUMAN, Q7L5D6 (See protein sequence)
Recommended Name: Golgi to ER traffic protein 4 homolog  
Size: 327 amino acids; 36504 Da
Subunit: Component of the BAT3 complex, at least composed of BAG6/BAT3, UBL4A and GET3/TRC35
Secondary accessions: A4D2Q1 B3KNC7 Q9UFC9 Q9Y309
Alternative splicing: 2 isoforms:  Q7L5D6-1   Q7L5D6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GET4: NX_Q7L5D6

Explore proteomics data for GET4 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See GET4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057033.2  
    ENSEMBL proteins: 
     ENSP00000265857   ENSP00000414097   ENSP00000385646   ENSP00000390288   ENSP00000407113  

    GET4 Human Recombinant Protein Products:

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    Novus Biologicals GET4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GET4

     
    Search eBioscience for Proteins for GET4 

     
    antibodies-online proteins for GET4 (7 products) 

     
    antibodies-online peptides for GET4

    GET4 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    ThermoFisher Antibodies for GET4
    antibodies-online antibodies for GET4 (16 products) 

    GET4 Assay Products:

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    Cloud-Clone Corp. ELISAs for GET4
    Cloud-Clone Corp. CLIAs for GET4
    Search eBioscience for ELISAs for GET4 
    antibodies-online kits for GET4 (5 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007317 UPF0363

    Graphical View of Domain Structure for InterPro Entry Q7L5D6

    ProtoNet protein and cluster: Q7L5D6

    UniProtKB/Swiss-Prot: GET4_HUMAN, Q7L5D6
    Similarity: Belongs to the GET4 family


    Find genes that share domains with GET4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GET4_HUMAN, Q7L5D6
    Function: Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of
    tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type
    II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA
    proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the
    transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting

    Phenotypes:
         1 GenomeRNAi human phenotype for GET4:

     Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for GET4

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate GET4 (see all 15):
    hsa-miR-3690 hsa-miR-1283 hsa-miR-188-5p hsa-miR-4290 hsa-miR-218 hsa-miR-3667-3p hsa-miR-211 hsa-miR-483-3p
    SwitchGear 3'UTR luciferase reporter plasmidGET4 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat GET4

    Gene Editing
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    OriGene ORF clones in mouse, rat for GET4
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    GenScript: all cDNA clones in your preferred vector: GET4 (NM_015949)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GET4

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GET4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GET4_HUMAN, Q7L5D6: Cytoplasm, cytosol
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    endoplasmic reticulum2
    extracellular2
    golgi apparatus1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol IDA--
    GO:0071818BAT3 complex IDA--

    Find genes that share ontologies with GET4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GET4
    Interactions:

        Search GeneGlobe Interaction Network for GET4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for GET4 (Q7L5D62, 3 ENSP000002658574) via UniProtKB, MINT, STRING, and/or I2D (see all 85)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBAC2Q8NBM42, 3, ENSP000003839114MINT-65706 I2D: score=4 STRING: ENSP00000383911
    PTMSP209622, 3, ENSP000003100884MINT-65702 I2D: score=3 STRING: ENSP00000310088
    CAPNS1P046322, 3MINT-65700 I2D: score=5 
    EEF1GP266412, 3MINT-65703 I2D: score=5 
    KAT5Q929932, 3MINT-65708 I2D: score=5 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0071816tail-anchored membrane protein insertion into ER membrane IMP--

    Find genes that share ontologies with GET4           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GET4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for GET4 gene: 
    NM_015949.2  

    Unigene Cluster for GET4:

    Golgi to ER traffic protein 4 homolog (S. cerevisiae)
    Hs.107387  [show with all ESTs]
    Unigene Representative Sequence: AK125863
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265857(uc003sjl.1) ENST00000412734 ENST00000407192 ENST00000441491
    ENST00000426056 ENST00000483469 ENST00000464468
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate GET4 (see all 15):
    hsa-miR-3690 hsa-miR-1283 hsa-miR-188-5p hsa-miR-4290 hsa-miR-218 hsa-miR-3667-3p hsa-miR-211 hsa-miR-483-3p
    SwitchGear 3'UTR luciferase reporter plasmidGET4 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat GET4
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GET4 (NM_015949)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GET4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GET4
    Primer
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    OriGene qPCR primer pairs and template standards for GET4
    OriGene qSTAR qPCR primer pairs in human, mouse for GET4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GET4
      QuantiTect SYBR Green Assays in human, mouse, rat GET4
      QuantiFast Probe-based Assays in human, mouse, rat GET4

    Additional mRNA sequence: 

    AF132954.1 AK023560.1 AK024305.1 AK095251.1 AK097899.1 AK125863.1 AL133014.1 BC003550.1 

    22 DOTS entries:

    DT.100793661  DT.91765438  DT.75124368  DT.121052537  DT.87016818  DT.95192363  DT.121052489  DT.87016978 
    DT.121052407  DT.100029447  DT.121052461  DT.100688713  DT.100698237  DT.100730494  DT.100793662  DT.101983046 
    DT.121052426  DT.121052482  DT.75183138  DT.87016819  DT.95304329  DT.99984653 

    Selected AceView cDNA sequences (see all 313):

    BM763400 BE794638 AK125863 BM738625 BQ063861 CF139938 BM700094 CB146100 
    BU857557 CD674832 BM313676 BQ062238 CD107139 BI858137 BX105415 AW024080 
    AA897105 BF057579 BQ685989 CD674568 BU944545 BF516594 BU786730 BQ065562 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GET4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAAGGGGAA
    GET4 Expression
    About this image

    GET4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GET4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.107387
        Custom PCR Arrays for GET4
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GET4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for GET4 gene from Selected species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Get41 , 5 golgi to ER traffic protein 4 homolog (S. cerevisiae)1, 5 86.21(n)1
    94.98(a)1
      5 (78.23 cM)5
    676041  NM_026269.21  NP_080545.21 
     1392523245 
    chicken
    (Gallus gallus)
    Aves GET41 golgi to ER traffic protein 4 homolog (S. cerevisiae) 75.66(n)
    88.82(a)
      416450  NM_001006159.1  NP_001006159.1 
    lizard
    (Anolis carolinensis)
    Reptilia GET46
    golgi to ER traffic protein 4 homolog (S. cerevisi...
    89(a)
    1 ↔ 1
    GL343385.1(687402-694400)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.261962 Xenopus laevis transcribed sequence with moderate similarity more 76.73(n)    CD327513.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd15h012 Danio rerio, clone IMAGE5915010, mRNA 76.72(n)    BC049494.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG98531 CG9853 52.43(n)
    40(a)
      40557  NM_141207.5  NP_649464.1 
    worm
    (Caenorhabditis elegans)
    Secernentea cee-16
    Protein CEE-1 (cee-1) mRNA, complete cds
    25(a)
    1 ↔ 1
    III(4912207-4914135) WBGene00017825
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GET4(YOR164C)4
    GET41
    Protein with a role in insertion of tail-anchored proteins more4
    GET41
    40.79(n)1
    32.49(a)1
      15(644332-643394)4
    8543351, 4  NP_014807.31  NP_014807.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G632201 AT5G63220 44.08(n)
    34.42(a)
      836442  NM_125717.5  NP_201127.2 


    ENSEMBL Gene Tree for GET4 (if available)
    TreeFam Gene Tree for GET4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GET4 (see all 890)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1423011671,2
    C--915065(+) CCTGT-/AAATCCAACGGAG
    GAGTCTTCGGACCGA
    ACGGC
    1 -- us2k10--------
    rs102441691,2
    C,F,H--915095(+) CGAACC/GGCGAA 1 -- us2k19Minor allele frequency- G:0.12NA WA CSA 17
    rs759341361,2
    C,F--915215(+) GCAGCC/GTGACA 1 -- us2k11Minor allele frequency- G:0.07EA 120
    rs774525891,2
    C--915240(+) AGGCCG/AACCCA 1 -- us2k13Minor allele frequency- A:0.18CSA WA EA 240
    rs1878803221,2
    --915246(+) ACCCAA/GTTCCC 1 -- us2k10--------
    rs1919055281,2
    --915262(+) CAGCAA/GGACCC 1 -- us2k10--------
    rs1835919251,2
    --915318(+) CCAGCC/TACGGC 1 -- us2k10--------
    rs1874990731,2
    --915406(+) GGAGAC/GACAGT 1 -- us2k10--------
    rs1403221551,2
    --915436(+) TGGAGA/GGCAGT 1 -- us2k10--------
    rs1925983701,2
    --915452(+) GATCCC/TGGCTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GET4 (916189 - 936073 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for GET4 (see all 19):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1624512CNV Deletion17803354
    esv1790011CNV Deletion17803354
    esv2733673CNV Deletion23290073
    esv2733675CNV Deletion23290073
    esv2733674CNV Deletion23290073
    esv2733671CNV Deletion23290073
    nsv509182CNV Insertion20534489
    nsv5611CNV Insertion18451855
    nsv887134CNV Loss21882294
    nsv887128CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GET4
    DNA2.0 Custom Variant and Variant Library Synthesis for GET4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612056    OMIM disorders: --

    2 diseases for GET4:    
    About MalaCards
    erysipeloid    louping ill

    4 diseases from the University of Copenhagen DISEASES database for GET4:
    tick-borne encephalitis     Erysipeloid     Osteoporosis     Louping ill

    Find genes that share disorders with GET4           About GenesLikeMe


    Export disorders for GET4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GET4 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with GET4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A ribosome-associating factor chaperones tail-anchored membrane proteins. (PubMed id 20676083)1, 2, 3 Mariappan M....Hegde R.S. (Nature 2010)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    3. Crystal structure of Get4-Get5 complex and its interactions with Sgt2, Get3, and Ydj1. (PubMed id 20106980)1, 3 Chang Y.W....Wang C. (J. Biol. Chem. 2010)
    4. Genomic, evolutionary, and expression analyses of cee, an ancient gene involved in normal growth and development. (PubMed id 18249086)1, 2 Fernandes J.M.O.... Johnston I.A. (Genomics 2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    8. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    9. A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation. (PubMed id 23665563)1 Xu Y....Ye Y. (J. Biol. Chem. 2013)
    10. Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage signaling and cell death. (PubMed id 23723067)1 Krenciute G....Wang Y. (J. Biol. Chem. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51608 HGNC: 21690 AceView: C7orf20 Ensembl:ENSG00000239857 euGenes: HUgn51608
    ECgene: GET4 H-InvDB: GET4

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for GET4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GET4 gene:
    Search GeneIP for patents involving GET4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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