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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GET4 Gene

protein-coding   GIFtS: 49
GCID: GC07P000916

Golgi To ER Traffic Protein 4 Homolog (S. Cerevisiae)

(Previous name: chromosome 7 open reading frame 20)
(Previous symbol: C7orf20)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Golgi To ER Traffic Protein 4 Homolog (S. Cerevisiae)1 2     CGI-20 Protein1
C7orf201 2 3 5     Chromosome 7 Open Reading Frame 201
CEE2 3 5     Transmembrane Domain Recognition Complex1
Conserved Edge Protein1 2     H_NH1244M04.52
Conserved Edge-Expressed Protein2 3     Conserved Edge Expressed Protein2
Transmembrane Domain Recognition Complex 35 KDa Subunit2 3     Golgi To ER Traffic Protein 4 Homolog2
TRC352 3     Transmembrane Domain Recognition Complex, 35kDa2
35kDa1     

External Ids:    HGNC: 216901   Entrez Gene: 516082   Ensembl: ENSG000002398577   OMIM: 6120565   UniProtKB: Q7L5D63   

Export aliases for GET4 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for GET4 Gene: 
GET4 (golgi to ER traffic protein 4 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with GET4 include louping ill, and erysipeloid.

UniProtKB/Swiss-Prot: GET4_HUMAN, Q7L5D6
Function: Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of
tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type
II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA
proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the
transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting

Gene Wiki entry for GET4 (C7orf20) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NC_018918.2  NT_079592.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for GET4
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): GET4 promoter sequence
   Search SABiosciences Chromatin IP Primers for GET4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GET4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.3   Ensembl cytogenetic band:  7p22.3   HGNC cytogenetic band: 7p22.3

GET4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GET4 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P000916:  view genomic region     (about GC identifiers)

Start:
916,189 bp from pter      End:
936,073 bp from pter
Size:
19,885 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 971,141-990,596     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GET4_HUMAN, Q7L5D6 (See protein sequence)
Recommended Name: Golgi to ER traffic protein 4 homolog  
Size: 327 amino acids; 36504 Da
Subunit: Component of the BAT3 complex, at least composed of BAG6/BAT3, UBL4A and GET3/TRC35
Subcellular location: Cytoplasm, cytosol
Secondary accessions: A4D2Q1 B3KNC7 Q9UFC9 Q9Y309
Alternative splicing: 2 isoforms:  Q7L5D6-1   Q7L5D6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GET4: NX_Q7L5D6

Explore proteomics data for GET4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7L5D6

  • GET4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GET4 Protein Expression
    REFSEQ proteins: NP_057033.2  
    ENSEMBL proteins: 
     ENSP00000265857   ENSP00000414097   ENSP00000385646   ENSP00000390288   ENSP00000407113  

    Human Recombinant Protein Products for GET4: 
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    Novus Biologicals GET4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GET4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol IDA--
    GO:0071818BAT3 complex IDA--

    GET4 for ontologies           About GeneDecksing



    GET4 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for GET4 

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    Cloud-Clone Corp. ELISAs for GET4 
    Cloud-Clone Corp. CLIAs for GET4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007317 UPF0363

    Graphical View of Domain Structure for InterPro Entry Q7L5D6

    ProtoNet protein and cluster: Q7L5D6

    UniProtKB/Swiss-Prot: GET4_HUMAN, Q7L5D6
    Similarity: Belongs to the GET4 family


    GET4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GET4_HUMAN, Q7L5D6
    Function: Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of
    tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type
    II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA
    proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the
    transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting

    Phenotypes:
         1 GenomeRNAi human phenotype for GET4:

     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for GET4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GET4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GET4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GET4 

    miRNA
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    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate GET4 (see all 15):
    hsa-miR-3690 hsa-miR-1283 hsa-miR-188-5p hsa-miR-4290 hsa-miR-218 hsa-miR-3667-3p hsa-miR-211 hsa-miR-483-3p
    SwitchGear 3'UTR luciferase reporter plasmidGET4 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    In Situ Assay
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GET4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    5/49 Interacting proteins for GET4 (Q7L5D62, 3 ENSP000002658574) via UniProtKB, MINT, STRING, and/or I2D (see all 49)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBAC2Q8NBM42, 3, ENSP000003839114MINT-65706 I2D: score=4 STRING: ENSP00000383911
    PTMSP209622, 3, ENSP000003100884MINT-65702 I2D: score=3 STRING: ENSP00000310088
    CAPNS1P046322, 3MINT-65700 I2D: score=5 
    EEF1GP266412, 3MINT-65703 I2D: score=5 
    KAT5Q929932, 3MINT-65708 I2D: score=5 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0071816tail-anchored membrane protein insertion into ER membrane IMP--

    GET4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GET4

    Search CenterWatch for drugs/clinical trials and news about GET4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GET4 gene: 
    NM_015949.2  

    Unigene Cluster for GET4:

    Golgi to ER traffic protein 4 homolog (S. cerevisiae)
    Hs.107387  [show with all ESTs]
    Unigene Representative Sequence: AK125863
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265857(uc003sjl.1) ENST00000412734 ENST00000407192 ENST00000441491
    ENST00000426056 ENST00000483469 ENST00000464468
    miRNA
    Products:
         
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    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate GET4 (see all 15):
    hsa-miR-3690 hsa-miR-1283 hsa-miR-188-5p hsa-miR-4290 hsa-miR-218 hsa-miR-3667-3p hsa-miR-211 hsa-miR-483-3p
    SwitchGear 3'UTR luciferase reporter plasmidGET4 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GET4
    Sirion Biotech Customized lentivirus for stable overexpression of GET4 
                         Customized lentivirus expression plasmids for stable overexpression of GET4 
    Primer
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    OriGene qPCR primer pairs and template standards for GET4
    OriGene qSTAR qPCR primer pairs in human, mouse for GET4
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GET4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GET4

    Additional mRNA sequence: 

    AF132954.1 AK023560.1 AK024305.1 AK095251.1 AK097899.1 AK125863.1 AL133014.1 BC003550.1 

    22 DOTS entries:

    DT.100793661  DT.91765438  DT.75124368  DT.121052537  DT.87016818  DT.95192363  DT.121052489  DT.87016978 
    DT.121052407  DT.100029447  DT.121052461  DT.100688713  DT.100698237  DT.100730494  DT.100793662  DT.101983046 
    DT.121052426  DT.121052482  DT.75183138  DT.87016819  DT.95304329  DT.99984653 

    24/313 AceView cDNA sequences (see all 313):

    AA897105 AI659756 CA488128 AI200352 AI872764 BM738625 BX105415 NM_015949 
    AW293273 CB146100 BM313676 BU857557 BQ059221 AI932724 CD674568 BE794638 
    AK125863 BQ065562 BQ059798 BM772296 AL133014 CF139938 BC003550 CD367910 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GET4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAAGGGGAA
    GET4 Expression
    About this image


    See GET4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GET4

    SOURCE GeneReport for Unigene cluster: Hs.107387
        SABiosciences Custom PCR Arrays for GET4
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GET4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for GET4 gene from 9/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Get41 , 5 golgi to ER traffic protein 4 homolog (S. cerevisiae)1, 5 86.44(n)1
    95.11(a)1
      5 (78.23 cM)5
    676041  NM_026269.21  NP_080545.21 
     1392523245 
    chicken
    (Gallus gallus)
    Aves GET41 golgi to ER traffic protein 4 homolog (S. cerevisiae) 75.43(n)
    88.14(a)
      416450  NM_001006159.1  NP_001006159.1 
    lizard
    (Anolis carolinensis)
    Reptilia GET46
    Uncharacterized protein
    88(a)
    1 ↔ 1
    GL343385.1(687402-694400)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.261962 Xenopus laevis transcribed sequence with moderate similarity more 76.73(n)    CD327513.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd15h012 Danio rerio, clone IMAGE5915010, mRNA 76.72(n)    BC049494.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG98531 CG9853 52.32(n)
    40(a)
      40557  NM_141207.4  NP_649464.1 
    worm
    (Caenorhabditis elegans)
    Secernentea cee-11 Protein CEE-1 40.05(n)
    31.72(a)
      175658  NM_065633.6  NP_498034.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GET4(YOR164C)4
    GET41
    Protein with a role in insertion of tail-anchored proteins more4
    Get4p1
    41.05(n)1
    32.35(a)1
      15(644332-643394)4
    8543351, 4  NP_014807.31  NP_014807.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G632201 hypothetical protein 43.96(n)
    34.78(a)
      836442  NM_125717.5  NP_201127.2 


    ENSEMBL Gene Tree for GET4 (if available)
    TreeFam Gene Tree for GET4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/890 SNPs in GET4 are shown (see all 890)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1423011671,2
    C--915065(+) CCTGT-/AAATCCAACGGAG
    GAGTCTTCGGACCGA
    ACGGC
    1 -- us2k10--------
    rs102441691,2
    C,F,H--915095(+) CGAACC/GGCGAA 1 -- us2k19Minor allele frequency- G:0.12NA WA CSA 17
    rs759341361,2
    C,F--915215(+) GCAGCC/GTGACA 1 -- us2k11Minor allele frequency- G:0.07EA 120
    rs774525891,2
    C--915240(+) AGGCCG/AACCCA 1 -- us2k13Minor allele frequency- A:0.18CSA WA EA 240
    rs1878803221,2
    --915246(+) ACCCAA/GTTCCC 1 -- us2k10--------
    rs1919055281,2
    --915262(+) CAGCAA/GGACCC 1 -- us2k10--------
    rs1835919251,2
    --915318(+) CCAGCC/TACGGC 1 -- us2k10--------
    rs1874990731,2
    --915406(+) GGAGAC/GACAGT 1 -- us2k10--------
    rs1403221551,2
    --915436(+) TGGAGA/GGCAGT 1 -- us2k10--------
    rs1925983701,2
    --915452(+) GATCCC/TGGCTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GET4 (916189 - 936073 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/19 variations for GET4 (see all 19):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1624512CNV Deletion17803354
    esv1790011CNV Deletion17803354
    esv2733673CNV Deletion23290073
    esv2733675CNV Deletion23290073
    esv2733674CNV Deletion23290073
    esv2733671CNV Deletion23290073
    nsv509182CNV Insertion20534489
    nsv5611CNV Insertion18451855
    nsv887134CNV Loss21882294
    nsv887128CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing GET4
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612056    OMIM disorders: --

    6 diseases for GET4:    About MalaCards
    louping ill    erysipeloid    tick-borne encephalitis    cerebrovascular accident
    encephalitis    gastric cancer

    4 diseases from the University of Copenhagen DISEASES database for GET4:
    tick-borne encephalitis     Erysipeloid     Osteoporosis     Louping ill

    GET4 for disorders           About GeneDecksing


    Export disorders for GET4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GET4 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with GET4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A ribosome-associating factor chaperones tail-anchore d membrane proteins. (PubMed id 20676083)1, 2, 3 Mariappan M....Hegde R.S. (2010)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    3. Crystal structure of Get4-Get5 complex and its intera ctions with Sgt2, Get3, and Ydj1. (PubMed id 20106980)1, 3 Chang Y.W....Wang C. (2010)
    4. Genomic, evolutionary, and expression analyses of cee, an ancient gene involved in normal growth and development. (PubMed id 18249086)1, 2 Fernandes J.M....Johnston I.A. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    8. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    9. A ubiquitin-like domain recruits an oligomeric chapero ne to a retrotranslocation complex in endoplasmic reticulum-associated degradati on. (PubMed id 23665563)1 Xu Y....Ye Y. (2013)
    10. Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage si gnaling and cell death. (PubMed id 23723067)1 Krenciute G....Wang Y. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51608 HGNC: 21690 AceView: C7orf20 Ensembl:ENSG00000239857 euGenes: HUgn51608
    ECgene: GET4 H-InvDB: GET4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GET4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GET4 gene:
    Search GeneIP for patents involving GET4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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