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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GEMIN4 Gene

protein-coding   GIFtS: 58
GCID: GC17M000693

Gem (Nuclear Organelle) Associated Protein 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Gem (Nuclear Organelle) Associated Protein 41 2     HCAP12
Component Of Gems 41 2 3     HHRF-12
HCC-Associated Protein 11 2     Gem-Associated Protein 42
p972 3     gemin-42
HC562     Gemin-43

External Ids:    HGNC: 157171   Entrez Gene: 506282   Ensembl: ENSG000001794097   OMIM: 6069695   UniProtKB: P576783   

Export aliases for GEMIN4 gene to outside databases

Previous GC identifers: GC17U990191 GC17M000851 GC17M000601 GC17M000632 GC17M000594 GC17M000558 GC17M000650 GC17M000651 GC17M000652 GC17M000660 GC17M000677


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GEMIN4 Gene:
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear
bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and
regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts
with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have
been described, but their biological validity has not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for GEMIN4 Gene: 
GEMIN4 (gem (nuclear organelle) associated protein 4) is a protein-coding gene. Diseases associated with GEMIN4 include spinal muscular atrophy, and muscular atrophy, and among its related super-pathways are Metabolism of non-coding RNA and Metabolism of mRNA. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: GEMI4_HUMAN, P57678
Function: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required
for pre-mRNA splicing in the nucleus

Gene Wiki entry for GEMIN4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010718.16  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GEMIN4 gene promoter:
         RP58   ISGF-3   AML1a   AP-4   XBP-1   RelA   NF-kappaB   E47   FOXL1   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGEMIN4 promoter sequence
   Search SABiosciences Chromatin IP Primers for GEMIN4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GEMIN4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13   Ensembl cytogenetic band:  17p13.3   HGNC cytogenetic band: 17p13.3

GEMIN4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GEMIN4 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M000693:  view genomic region     (about GC identifiers)

Start:
647,654 bp from pter      End:
657,239 bp from pter
Size:
9,586 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GEMI4_HUMAN, P57678 (See protein sequence)
Recommended Name: Gem-associated protein 4  
Size: 1058 amino acids; 120037 Da
Subunit: Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6,
GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts directly with GEMIN3 and with several snRNP SM core proteins, including
SNRPB, SNRPD1, SNRPD2, SNRPD3 and SNRPE. Interacts with PPP4R2
Subcellular location: Cytoplasm. Nucleus. Nucleus, nucleolus. Nucleus, gem. Note=Localized in subnuclear
structures next to coiled bodies, called gems, which are highly enriched in spliceosomal snRNPs and in the
nucleolus
Secondary accessions: Q9NZS7 Q9UG32 Q9Y4Q2

Explore the universe of human proteins at neXtProt for GEMIN4: NX_P57678

Explore proteomics data for GEMIN4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P57678

  • GEMIN4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GEMIN4 Protein Expression
    REFSEQ proteins: NP_056536.2  
    ENSEMBL proteins: 
     ENSP00000321706   ENSP00000459565   ENSP00000392460   ENSP00000460286   ENSP00000461103  
     ENSP00000461368   ENSP00000458896  
    Reactome Protein details: P57678
    Human Recombinant Protein Products for GEMIN4: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse Sino Biological Recombinant Proteins
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GEMIN4 

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--
    GO:0005681spliceosomal complex IEA--
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm TAS10725331
    GO:0005829cytosol TAS--

    GEMIN4 for ontologies           About GeneDecksing



    GEMIN4 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: P57678


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GEMI4_HUMAN, P57678
    Function: The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required
    for pre-mRNA splicing in the nucleus

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11714716
         
    GEMIN4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for GEMIN4 
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    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate GEMIN4:
    hsa-miR-520d-5p hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidGEMIN4 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GEMIN4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1snRNP Assembly
    Metabolism of non-coding RNA1.00
    snRNP Assembly1.00
    2Metabolism of mRNA
    Metabolism of RNA0.92
    3Generic Transcription Pathway
    Gene Expression0.47
    4RNA transport
    RNA transport

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for GEMIN4
        snRNP Assembly
    Metabolism of RNA
    Gene Expression
    Metabolism of non-coding RNA


    1         Kegg Pathway  (Kegg details for GEMIN4):
        RNA transport


    GEMIN4 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GEMIN4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/975 Interacting proteins for GEMIN4 (P576782, 3 ENSP000003217064) via UniProtKB, MINT, STRING, and/or I2D (see all 975)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DHX9Q082112, 3, ENSP000003565204MINT-7945693 MINT-6489539 MINT-6488590 MINT-6489355 MINT-6488791 I2D: score=3 STRING: ENSP00000356520
    SMN1Q166372, 3, ENSP000003700834MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000370083
    FBLP220872, 3, ENSP000002218014MINT-6489539 MINT-6489355 I2D: score=1 STRING: ENSP00000221801
    GEMIN6Q8WXD52, 3, ENSP000002819504MINT-7947479 I2D: score=1 STRING: ENSP00000281950
    SNRPD1P623142, 3, ENSP000003004134MINT-7947479 I2D: score=1 STRING: ENSP00000300413
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000387spliceosomal snRNP assembly TAS--
    GO:0006364rRNA processing TAS10725331
    GO:0010467gene expression TAS--
    GO:0016070RNA metabolic process TAS--
    GO:0034660ncRNA metabolic process TAS--

    GEMIN4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GEMIN4 (GEMI4)

    Search CenterWatch for drugs/clinical trials and news about GEMIN4 / GEMI4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GEMIN4 gene: 
    NM_015721.2  

    Unigene Cluster for GEMIN4:

    Gem (nuclear organelle) associated protein 4
    Hs.499620  [show with all ESTs]
    Unigene Representative Sequence: AF177341
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000319004(uc002frs.1 uc010vqa.1) ENST00000576778 ENST00000437269
    ENST00000573482 ENST00000570364 ENST00000576383 ENST00000574958
    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate GEMIN4:
    hsa-miR-520d-5p hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidGEMIN4 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GEMIN4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GEMIN4

    Additional mRNA sequence: 

    AF173856.1 AF177341.2 AK302722.1 AL080150.1 AL080167.1 BC020062.1 BC032084.1 BC036024.1 

    8 DOTS entries:

    DT.214844  DT.100755019  DT.86856156  DT.439873  DT.100654099  DT.100697152  DT.100755020  DT.405784 

    24/220 AceView cDNA sequences (see all 220):

    AA921699 AA417871 W02084 BG413343 BQ065529 R06075 BQ652561 CN483779 
    AA577437 BM480173 BE780403 BE257360 BU165407 AI738467 BQ223741 AI863662 
    CD558056 BQ214337 AW419190 BQ648905 BE208612 AA830928 AW016516 BM005873 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GEMIN4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAATAATGG
    GEMIN4 Expression
    About this image


    See GEMIN4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GEMIN4

    SOURCE GeneReport for Unigene cluster: Hs.499620
        SABiosciences Custom PCR Arrays for GEMIN4
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GEMIN4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for GEMIN4 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gemin41 , 5 gem (nuclear organelle) associated protein 41, 5 82.04(n)1
    81.66(a)1
      11 (45.92 cM)5
    2769191  NM_177367.31  NP_796341.21 
     762105715 
    chicken
    (Gallus gallus)
    Aves GEMIN41 gem (nuclear organelle) associated protein 4 61.31(n)
    52.25(a)
      427835  NM_001012610.1  NP_001012628.1 
    lizard
    (Anolis carolinensis)
    Reptilia GEMIN46
    Uncharacterized protein
    46(a)
    1 ↔ 1
    GL344108.1(61497-71478)
    zebrafish
    (Danio rerio)
    Actinopterygii gemin41 gem (nuclear organelle) associated protein 4 48.12(n)
    35.46(a)
      324754  NM_001018144.1  NP_001018154.1 


    ENSEMBL Gene Tree for GEMIN4 (if available)
    TreeFam Gene Tree for GEMIN4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/367 SNPs in GEMIN4 are shown (see all 367)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1838628091,2
    --568390(+) TTAATA/GATCAC 1 -- us2k10--------
    rs1477862221,2
    C--568466(+) AGGCAG/TGTCTA 1 -- us2k10--------
    rs345323941,2
    C--647144(+) AGACT-/GTACACA 1 -- ds50010--------
    rs1920539281,2
    --647181(+) AAACCA/GTTCAT 1 -- ds50010--------
    rs681528401,2
    C,F--647188(+) TCATTC/AATCCA 1 -- ds50016Minor allele frequency- A:0.17NA WA EA 364
    rs1497932281,2
    --647249(+) GCACAC/TCTCTG 1 -- ds50010--------
    rs1844394681,2
    --647297(+) TGGGGA/GTGACT 1 -- ds50010--------
    rs1892001271,2
    --647326(+) CTGTAG/TGGGAA 1 -- ds50010--------
    rs350570001,2
    C--647424(+) AAGAC-/TGTACAC 1 -- ds50010--------
    rs1457865811,2
    --647529(+) GAATTA/GTGCAG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for GEMIN4 (647654 - 657239 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for GEMIN4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2422420CNV Duplication17116639
    nsv457631CNV Gain19166990
    esv673CNV CNV17122850
    dgv925e1CNV Complex17122850
    nsv469891CNV Complex16826518


    Human Gene Mutation Database (HGMD): GEMIN4
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing GEMIN4
    DNA2.0 Custom Variant and Variant Library Synthesis for GEMIN4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606969    OMIM disorders: --

    11 diseases for GEMIN4:    About MalaCards
    spinal muscular atrophy    muscular atrophy    esophageal cancer    renal cell carcinoma
    esophagitis    colon cancer    hepatocellular carcinoma    lung cancer
    prostate cancer    neuronitis    prostatitis

    2 diseases from the University of Copenhagen DISEASES database for GEMIN4:
    Muscular atrophy     Spinal muscular atrophy

    GEMIN4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): GEMIN4
    Human Genome Epidemiology (HuGE) Navigator: GEMIN4 (9 documents)

    Export disorders for GEMIN4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GEMIN4 gene, integrated from 9 sources (see all 63):
    (articles sorted by number of sources associating them with GEMIN4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Gemin4: a novel component of the SMN complex that is found in both gems and nucleoli. (PubMed id 10725331)1, 2, 3, 9 Charroux B.... Dreyfuss G. (2000)
    2. Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma. (PubMed id 19047128)1, 4, 9 Horikawa Y....Wu X. (2008)
    3. MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage he ad and neck cancer. (PubMed id 20819778)1, 4 Zhang X....Wu X. (2010)
    4. Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study. (PubMed id 20721975)1, 4 Kim J.S....Park J.Y. (2010)
    5. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PubMed id 19851984)1, 4 Clague J....Wu X. (2010)
    6. Genetic variations in microRNA-related genes are asso ciated with survival and recurrence in patients with renal cell carcinoma. (PubMed id 20732906)1, 4 Lin J....Wu X. (2010)
    7. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PubMed id 19138993)1, 4 Ye Y....Wu X. (2008)
    8. Protein phosphatase 4 interacts with the survival of motor neurons complex and enhances the temporal localisation of snRNPs. (PubMed id 12668731)1, 2 Carnegie G.K.... Cohen P.T.W. (2003)
    9. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    10. Identification and characterisation of a nuclear localisation signal in the SMN associated protein, Gemin4. (PubMed id 18675250)1, 9 Lorson M.A....Young P.J. (2008)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 50628 HGNC: 15717 AceView: GEMIN4 Ensembl:ENSG00000179409 euGenes: HUgn50628
    ECgene: GEMIN4 Kegg: 50628 H-InvDB: GEMIN4

    (According to HUGE)
    About This Section
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GEMIN4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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