Aliases for GDF15 Gene
External Ids for GDF15 Gene
Previous GeneCards Identifiers for GDF15 Gene
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]
GeneCards Summary for GDF15 Gene
GDF15 (Growth Differentiation Factor 15) is a Protein Coding gene. Diseases associated with GDF15 include estrogen resistance and oral cavity cancer. Among its related pathways are NF-KappaB Family Pathway and NF-KappaB Family Pathway. GO annotations related to this gene include cytokine activity and growth factor activity. An important paralog of this gene is NODAL.