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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GDF11 Gene

protein-coding   GIFtS: 54
GCID: GC12P056137

Growth Differentiation Factor 11

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Growth Differentiation Factor 111 2
BMP112 3 5
Bone Morphogenetic Protein 112 3
BMP-112 3
GDF-112 3
Growth/Differentiation Factor 112

External Ids:    HGNC: 42161   Entrez Gene: 102202   Ensembl: ENSG000001354147   OMIM: 6039365   UniProtKB: O953903   

Export aliases for GDF11 gene to outside databases

Previous GC identifers: GC12P056061 GC12P056210 GC12P055853 GC12P054423 GC12P053175


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GDF11 Gene:
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta
superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved
to produce a mature protein containing seven conserved cysteine residues. The members of this family are
regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus
suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
(provided by RefSeq, Jul 2008)

GeneCards Summary for GDF11 Gene: 
GDF11 (growth differentiation factor 11) is a protein-coding gene. Diseases associated with GDF11 include low tension glaucoma, and glaucoma. GO annotations related to this gene include growth factor activity and cytokine activity. An important paralog of this gene is TGFB3.

UniProtKB/Swiss-Prot: GDF11_HUMAN, O95390
Function: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis
during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the
skeletal pattern

Gene Wiki entry for GDF11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GDF11 gene promoter:
         GR   C/EBPbeta   Sp1   GR-beta   Nkx2-5   c-Ets-1   HEN1   GR-alpha   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGDF11 promoter sequence
   Search SABiosciences Chromatin IP Primers for GDF11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GDF11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.2   Ensembl cytogenetic band:  12q13.2   HGNC cytogenetic band: 12q13.13

GDF11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GDF11 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P056137:  view genomic region     (about GC identifiers)

Start:
56,137,064 bp from pter      End:
56,150,911 bp from pter
Size:
13,848 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GDF11_HUMAN, O95390 (See protein sequence)
Recommended Name: Growth/differentiation factor 11 precursor  
Size: 407 amino acids; 45091 Da
Subunit: Homodimer; disulfide-linked (By similarity)
Subcellular location: Secreted (Probable)
Secondary accessions: Q9UID1 Q9UID2

Explore the universe of human proteins at neXtProt for GDF11: NX_O95390

Explore proteomics data for GDF11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95390

  • GDF11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GDF11 Protein Expression
    REFSEQ proteins: NP_005802.1  
    ENSEMBL proteins: 
     ENSP00000257868   ENSP00000448390  

    Human Recombinant Protein Products for GDF11: 
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    Novus Biologicals GDF11 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GDF11 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005615extracellular space IEA--

    GDF11 for ontologies           About GeneDecksing



    GDF11 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for GDF11


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR001111 TGF-b_N
     IPR015615 TGF-beta-rel
     IPR001839 TGF-b_C
     IPR017948 TGFb_CS

    Graphical View of Domain Structure for InterPro Entry O95390

    ProtoNet protein and cluster: O95390

    2 Blocks protein domains:
    IPB001111 Transforming growth factor beta (TGFb)
    IPB001839 Transforming growth factor beta (TGFb)


    UniProtKB/Swiss-Prot: GDF11_HUMAN, O95390
    Similarity: Belongs to the TGF-beta family


    GDF11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GDF11_HUMAN, O95390
    Function: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis
    during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the
    skeletal pattern

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005125cytokine activity NAS--
    GO:0005515protein binding ----
    GO:0008083growth factor activity IEA--
         
    GDF11 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for GDF11:
     Decreased Salmonella enterica   Decreased homologous recombina 

         15/19 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Gdf11) (see all 19):
     cardiovascular system  cellular  craniofacial  digestive/alimentary  embryogenesis 
     endocrine/exocrine gland  growth/size  hematopoietic system  homeostasis/metabolism  immune system 
     limbs/digits/tail  mortality/aging  muscle  nervous system  renal/urinary system 

    GDF11 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for GDF11: Gdf11tm2.2Sjl Gdf11tm1Clf Gdf11tm1Sjl

       inGenious Targeting Laboratory - Custom generated mouse model solutions for GDF11 
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    miRNA
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    8/134 QIAGEN miScript miRNA Assays for microRNAs that regulate GDF11 (see all 134):
    hsa-miR-193a-3p hsa-miR-3938 hsa-miR-520f hsa-miR-631 hsa-miR-106a hsa-miR-128 hsa-miR-519a hsa-miR-3170
    SwitchGear 3'UTR luciferase reporter plasmidGDF11 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GDF11


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GDF11

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/6 Interacting proteins for GDF11 (O953902, 3 ENSP000002578684) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACVR2BQ137052, 3, ENSP000003403614MINT-8044205 I2D: score=3 STRING: ENSP00000340361
    WFIKKN1Q96NZ83, ENSP000003247634I2D: score=1 STRING: ENSP00000324763
    WFIKKN2Q8TEU83, ENSP000003111844I2D: score=1 STRING: ENSP00000311184
    --Q612712MINT-2842299
    --Q8K3482MINT-2842380
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001501skeletal system development TAS10391213
    GO:0001656metanephros development IEA--
    GO:0001657ureteric bud development IEA--
    GO:0007399nervous system development TAS10075854
    GO:0007498mesoderm development TAS10075854

    GDF11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GDF11

    Search CenterWatch for drugs/clinical trials and news about GDF11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GDF11 gene: 
    NM_005811.3  

    Unigene Cluster for GDF11:

    Growth differentiation factor 11
    Hs.600883  [show with all ESTs]
    Unigene Representative Sequence: NM_005811
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000257868(uc001shq.3) ENST00000546799
    miRNA
    Products:
         
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    8/134 QIAGEN miScript miRNA Assays for microRNAs that regulate GDF11 (see all 134):
    hsa-miR-193a-3p hsa-miR-3938 hsa-miR-520f hsa-miR-631 hsa-miR-106a hsa-miR-128 hsa-miR-519a hsa-miR-3170
    SwitchGear 3'UTR luciferase reporter plasmidGDF11 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GDF11
    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GDF11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GDF11
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GDF11
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GDF11

    Additional mRNA sequence: 

    AF028333.1 AF100907.1 AK091091.1 

    7 DOTS entries:

    DT.121194657  DT.100020515  DT.430003  DT.95135754  DT.313388  DT.99936459  DT.92459617 

    24/191 AceView cDNA sequences (see all 191):

    AI655774 BU625797 AW173253 AF028333 AI263443 BU732952 AI916904 AI335632 
    AA777215 BM718106 AI263821 AK091091 N52656 AA548755 Z42173 BI869431 
    BX280443 BU508081 BF516009 BU682663 AI884806 BM683293 BM694432 BM722391 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GDF11 expression in normal human tissues (normalized intensities)      GDF11 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACACAATCCA
    GDF11 Expression
    About this image


    GDF11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Muscle Progenitor Cells Mandibular Arch Muscles
     
     Nose (Sensory Organs)
             sensory organ/nose/nasal cavity   
     
     Uterus (Reproductive System)
             endometrial endothelial cell   
     
     Eye (Sensory Organs)
             Mature Ganglion Cells Ganglion Cell Layer

    See GDF11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GDF11

    SOURCE GeneReport for Unigene cluster: Hs.600883
        SABiosciences Expression via Pathway-Focused PCR Array including GDF11: 
              Growth Factors in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GDF11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GDF11 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gdf111 , 5 growth differentiation factor 111, 5 94.49(n)1
    99.51(a)1
      10 (77.18 cM)5
    145611  NM_010272.11  NP_034402.11 
     1288822955 
    lizard
    (Anolis carolinensis)
    Reptilia GDF116
    Uncharacterized protein
    77(a)
    1 ↔ 1
    GL343198.1(3034380-3059436)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.136382 Xenopus laevis transcribed sequence with moderate similarity more 78.44(n)    BJ034907.1 
    zebrafish
    (Danio rerio)
    Actinopterygii gdf82 growth differentiation factor 8 77.16(n)   30215  AF019626.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta myo6
    myoglianin
    17(a)
    1 → many
    4(711890-716675)
    worm
    (Caenorhabditis elegans)
    Secernentea daf-71 Protein DAF-7 43.65(n)
    29.97(a)
      175237  NM_064864.3  NP_497265.1 


    ENSEMBL Gene Tree for GDF11 (if available)
    TreeFam Gene Tree for GDF11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GDF11 gene
    TGFB32  INHBC2  MSTN2  INHBE2  INHBA2  TGFB12  TGFB22  INHBB2  
    2 SIMAP similar genes for GDF11 using alignment to 2 protein entries:     GDF11_HUMAN (see all proteins):
    MSTN    GDF8

    GDF11 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/171 SNPs in GDF11 are shown (see all 171)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1995571581,2
    C--56135194(+) CTTTTC/TTTTTT 1 -- us2k10--------
    rs1894816571,2
    C--56135199(+) CTTTTC/TTTTTT 1 -- us2k10--------
    rs1810246571,2
    C--56135262(+) ATCTCA/GGCTCA 1 -- us2k10--------
    rs1844059551,2
    --56135401(+) GTTAGC/GCAGGA 1 -- us2k10--------
    rs1417999731,2
    --56135472(+) CAGGCC/GTGAGC 1 -- us2k10--------
    rs1892731411,2
    --56135490(+) CCTGGC/TCTGGC 1 -- us2k10--------
    rs1819531311,2
    --56135494(+) GCCTGA/GCACAA 1 -- us2k10--------
    rs1505529071,2
    --56135517(+) TGACTA/GTTGCT 1 -- us2k10--------
    rs1156904091,2
    C,F--56135963(+) TCCCAT/CCACCT 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1864110171,2
    --56136123(+) TCCACC/TTCTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GDF11 (56137064 - 56150911 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for GDF11:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv469410CNV Loss19166990
    nsv832423CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603936    OMIM disorders: --

    5 diseases for GDF11:    About MalaCards
    low tension glaucoma    glaucoma    retinitis    colorectal cancer
    neuronitis


    GDF11 for disorders           About GeneDecksing

    Genetic Association Database (GAD): GDF11
    Human Genome Epidemiology (HuGE) Navigator: GDF11 (1 document)

    Export disorders for GDF11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GDF11 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with GDF11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells. (PubMed id 15988002)1, 3, 9 Ge G....Greenspan D.S. (2005)
    2. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (2010)
    3. A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos. (PubMed id 10075854)1, 2 Gamer L.W....Rosen V. (1999)
    4. Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11. (PubMed id 10391213)1, 2 McPherron A.C.... Lee S.-J. (1999)
    5. Clinical significance of growth differentiation factor 11 in colorectal cancer. (PubMed id 17912435)1, 9 Yokoe T....Mori M. (2007)
    6. BMP-11 and myostatin support undifferentiated growth of human embryonic stem cells in feeder-free cultures. (PubMed id 19751112)1 Hannan N.R....Wolvetang E.J. (2009)
    7. TGFbeta ligands promote the initiation of retinal ganglion cell dendrites in vitro and in vivo. (PubMed id 17997109)1 Hocking J.C....McFarlane S. (2008)
    8. VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5. (PubMed id 18519639)1 Szumska D....Bhattacharya S. (2008)
    9. Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11. (PubMed id 18596030)1 Kondas K....Patthy L. (2008)
    10. Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin. (PubMed id 18535106)1 Schneyer A.L....Krasney P.A. (2008)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10220 HGNC: 4216 AceView: GDF11 Ensembl:ENSG00000135414 euGenes: HUgn10220
    ECgene: GDF11 H-InvDB: GDF11

    (According to HUGE)
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    About This Section
    NameDescription
    PharmGKB entry for GDF11 Pharmacogenomics, SNPs, Pathways

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