Aliases for GDF10 Gene
External Ids for GDF10 Gene
Previous GeneCards Identifiers for GDF10 Gene
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for GDF10 Gene
GDF10 (Growth Differentiation Factor 10) is a Protein Coding gene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. GO annotations related to this gene include cytokine activity and transforming growth factor beta receptor binding. An important paralog of this gene is NODAL.
UniProtKB/Swiss-Prot for GDF10 Gene
Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis.