Aliases for GDF1 Gene
External Ids for GDF1 Gene
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Mar 2014]
GeneCards Summary for GDF1 Gene
GDF1 (Growth Differentiation Factor 1) is a Protein Coding gene. Diseases associated with GDF1 include right atrial isomerism and conotruncal heart malformations. Among its related pathways are L1CAM interactions and TGF-beta Signaling Pathway (sino). GO annotations related to this gene include cytokine activity and growth factor activity. An important paralog of this gene is BMP2.
UniProtKB/Swiss-Prot for GDF1 Gene
May mediate cell differentiation events during embryonic development