Aliases for GCNT3 Gene
External Ids for GCNT3 Gene
Previous GeneCards Identifiers for GCNT3 Gene
This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009]
GeneCards Summary for GCNT3 Gene
GCNT3 (Glucosaminyl (N-Acetyl) Transferase 3, Mucin Type) is a Protein Coding gene. Diseases associated with GCNT3 include colorectal cancer. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism. GO annotations related to this gene include acetylglucosaminyltransferase activity and N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity. An important paralog of this gene is GCNT1.
UniProtKB/Swiss-Prot for GCNT3 Gene
Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.