Aliases for GCFC2 Gene
External Ids for GCFC2 Gene
Previous HGNC Symbols for GCFC2 Gene
Previous GeneCards Identifiers for GCFC2 Gene
The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for GCFC2 Gene
GCFC2 (GC-Rich Sequence DNA-Binding Factor 2) is a Protein Coding gene. Among its related pathways are ERK Signaling and ERK Signaling. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is PAXBP1.
UniProtKB/Swiss-Prot for GCFC2 Gene
Factor that represses transcription. It binds to the GC-rich sequences (5-GCGGGGC-3) present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons.