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Aliases for GC09P009445 Gene

Subcategory (RNA class) for GC09P009445 Gene

SRP

Quality Score for this RNA gene is

2

Aliases for GC09P009445 Gene

No Aliases found

ORGUL Members for GC09P009445 Gene

No data available for External Ids for GC09P009445 Gene

Summaries for GC09P009445 Gene

GeneCards Summary for GC09P009445 Gene

GC09P009445 is an RNA Gene, and is affiliated with the SRP RNA class.

fRNAdb sequence ontologies for GC09P009445 Gene

  • Metazoan signal recognition particle RNA: The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. Eukaryotic and archaeal 7S RNAs have very similar secondary structures, as represented by this family. Eight helical elements fold into the Alu and S domains, separated by a long linker region [1,2]. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP [1]. The universally conserved helix which interacts with the SRP54 M domain mediates signal sequence recognition [2,3]. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilises helix 8 for SRP54 binding [1]. The Signal Recognition Particle Database (SRPDB) [4] provides compilations of SRP components, with phylogenetic data and structural illustrations. Many sequences below the threshold for this family are clearly closely related, but are most likely to be SRP RNA derived pseudogenes. The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats. While the threshold of this family is set high so as to minimise the number of hits to such regions, it is likely that some remain.

View fRNAdb secondary structures for GC09P009445

Additional gene information for GC09P009445 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for GC09P009445 Gene

Genomics for GC09P009445 Gene

Genomic Location for GC09P009445 Gene

Chromosome:
9
Start:
9,442,059 bp from pter
End:
9,442,354 bp from pter
Size:
296 bases
Orientation:
Plus strand

Genomic View for GC09P009445 Gene

Genes around GC09P009445 on UCSC Golden Path with GeneCards custom track

GC09P009445 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GC09P009445 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for GC09P009445 Gene

ORGUL Member Location for GC09P009445 gene

No data available for Regulatory Elements , Cytogenetic band and RefSeq DNA sequence for GC09P009445 Gene

Proteins for GC09P009445 Gene

Post-translational modifications for GC09P009445 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GC09P009445 Gene

Domains & Families for GC09P009445 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GC09P009445 Gene

Function for GC09P009445 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GC09P009445 Gene

Localization for GC09P009445 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GC09P009445 Gene

Pathways & Interactions for GC09P009445 Gene

SuperPathways for GC09P009445 Gene

No Data Available

Interacting Proteins for GC09P009445 Gene

Gene Ontology (GO) - Biological Process for GC09P009445 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GC09P009445 Gene

Drugs & Compounds for GC09P009445 Gene

No Compound Related Data Available

Transcripts for GC09P009445 Gene

fRNAdb Secondary structures for GC09P009445 Gene

  • FR294337
  • FR233324

Alternative Splicing Database (ASD) splice patterns (SP) for GC09P009445 Gene

No ASD Table

Relevant External Links for GC09P009445 Gene

GeneLoc Exon Structure for
GC09P009445

No data available for mRNA/cDNA for GC09P009445 Gene

Expression for GC09P009445 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GC09P009445 Gene

Orthologs for GC09P009445 Gene

No data available for Orthologs and Evolution for GC09P009445 Gene

Paralogs for GC09P009445 Gene

No data available for Paralogs for GC09P009445 Gene

Variants for GC09P009445 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for GC09P009445 Gene

Disorders for GC09P009445 Gene

No disorders were found for GC09P009445 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for GC09P009445 Gene

Publications for GC09P009445 Gene

  1. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C … Chen R (Nucleic acids research 2005) 1
  2. SRPDB: Signal Recognition Particle Database. (PMID: 12520023) Rosenblad MA … Samuelsson T (Nucleic acids research 2003) 1
  3. Structure, function and evolution of the signal recognition particle. (PMID: 12853463) Nagai K … Jovine L (The EMBO journal 2003) 1
  4. Prediction of signal recognition particle RNA genes. (PMID: 12140321) Regalia M … Samuelsson T (Nucleic acids research 2002) 1
  5. Towards the structure of the mammalian signal recognition particle. (PMID: 11839493) Wild K … Cusack S (Current opinion in structural biology 2002) 1

Products for GC09P009445 Gene

Sources for GC09P009445 Gene

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