Free for academic non-profit institutions. Other users need a Commercial license

Aliases for GC08P127736 Gene

Subcategory (RNA class) for GC08P127736 Gene

IRES

Quality Score for this RNA gene is

2

Aliases for GC08P127736 Gene

No Aliases found

No data available for External Ids for GC08P127736 Gene

Summaries for GC08P127736 Gene

GeneCards Summary for GC08P127736 Gene

GC08P127736 is an RNA Gene, and is affiliated with the IRES RNA class.

fRNAdb sequence ontologies for GC08P127736 Gene - the ORGUL cluster for this gene includes several descriptions:

  • internal_ribosome_entry_site: Sequence element that recruits a ribosomal subunit to internal mRNA for translation initiation.

  • c-myc internal ribosome entry site (IRES): This family represents the c-myc internal ribosome entry site (IRES). The mammalian c-myc gene is a proto-oncogene which is required for cell proliferation, transformation and death. c-myc mRNA has an alternative method of translation via internal ribosome entry where ribosomes are recruited to the IRES located in the 5' UTR thus bypassing the typical eukaryotic cap-dependent translation pathway [1].

View fRNAdb secondary structures for GC08P127736

Additional gene information for GC08P127736 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for GC08P127736 Gene

Genomics for GC08P127736 Gene

Genomic Location for GC08P127736 Gene

Chromosome:
8
Start:
127,736,243 bp from pter
End:
127,736,545 bp from pter
Size:
303 bases
Orientation:
Plus strand

Genomic View for GC08P127736 Gene

Genes around GC08P127736 on UCSC Golden Path with GeneCards custom track

GC08P127736 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GC08P127736 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for GC08P127736 Gene

ORGUL Member Location for GC08P127736 gene

No data available for Regulatory Elements , Cytogenetic band and RefSeq DNA sequence for GC08P127736 Gene

Proteins for GC08P127736 Gene

Post-translational modifications for GC08P127736 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GC08P127736 Gene

Domains & Families for GC08P127736 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GC08P127736 Gene

Function for GC08P127736 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GC08P127736 Gene

Localization for GC08P127736 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GC08P127736 Gene

Pathways & Interactions for GC08P127736 Gene

SuperPathways for GC08P127736 Gene

No Data Available

Interacting Proteins for GC08P127736 Gene

Gene Ontology (GO) - Biological Process for GC08P127736 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GC08P127736 Gene

Drugs & Compounds for GC08P127736 Gene

No Compound Related Data Available

Transcripts for GC08P127736 Gene

fRNAdb Secondary structures for GC08P127736 Gene

  • FR011824
  • FR310691
  • FR356140
  • FR262504

Alternative Splicing Database (ASD) splice patterns (SP) for GC08P127736 Gene

No ASD Table

Relevant External Links for GC08P127736 Gene

GeneLoc Exon Structure for
GC08P127736

No data available for mRNA/cDNA for GC08P127736 Gene

Expression for GC08P127736 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GC08P127736 Gene

Orthologs for GC08P127736 Gene

No data available for Orthologs and Evolution for GC08P127736 Gene

Paralogs for GC08P127736 Gene

No data available for Paralogs for GC08P127736 Gene

Variants for GC08P127736 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for GC08P127736 Gene

Disorders for GC08P127736 Gene

No disorders were found for GC08P127736 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for GC08P127736 Gene

Publications for GC08P127736 Gene

  1. Derivation of a structural model for the c-myc IRES. (PMID: 11419940) Le Quesne JP … Willis AE (Journal of molecular biology 2001) 1

Products for GC08P127736 Gene

Sources for GC08P127736 Gene

Content
Loading form....