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Aliases for GC07M144850 Gene

Subcategory (RNA class) for GC07M144850 Gene

7SK RNA

Quality Score for this RNA gene is

2

Aliases for GC07M144850 Gene

No Aliases found

ORGUL Members for GC07M144850 Gene

No data available for External Ids for GC07M144850 Gene

Summaries for GC07M144850 Gene

GeneCards Summary for GC07M144850 Gene

GC07M144850 is an RNA Gene, and is affiliated with the 7SK RNA class.

fRNAdb sequence ontologies for GC07M144850 Gene - the ORGUL cluster for this gene includes several descriptions:

  • snRNA: A small nuclear RNA molecule involved in pre-mRNA splicing and processing.

  • 7SK RNA: 7SK was discovered as an abundant small nuclear RNA in the mid-70s but a possible function has only recently been suggested [1]. Two independent studies have found that 7SK RNA binds the CDK9/cyclin T complex (known as elongation factor P-TEFb). P-TEFb activates transcription by phosphorylating the C-terminal domain of RNA polymerase II. This process is negatively regulated by the 7SK RNP. The secondary structure of 7SK RNA shown here was proposed by Wasserman and Steitz on the basis of chemical modification and enzymatic cleavage experiments [2]. This family contains a number of annotated pseudogenes and 7SK derived repeats. The threshold is artificially high to minimise the pseudogene count.

View fRNAdb secondary structures for GC07M144850

Additional gene information for GC07M144850 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for GC07M144850 Gene

Genomics for GC07M144850 Gene

Regulatory Elements for GC07M144850 Gene

Enhancers for GC07M144850 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H144841 1.4 FANTOM5 Ensembl ENCODE 0.4 +7.4 7409 1 ELK4 ATF1 SOX6 ETV1 BACH1 CEBPB ELF1 CEBPG ZEB2 ZBTB40 TPK1 RN7SKP174 GC07M144850
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GC07M144850 on UCSC Golden Path with GeneCards custom track

Genomic Location for GC07M144850 Gene

Chromosome:
7
Start:
144,849,753 bp from pter
End:
144,850,084 bp from pter
Size:
332 bases
Orientation:
Minus strand

Genomic View for GC07M144850 Gene

Genes around GC07M144850 on UCSC Golden Path with GeneCards custom track

GC07M144850 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GC07M144850 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for GC07M144850 Gene

ORGUL Member Location for GC07M144850 gene

No data available for Cytogenetic band and RefSeq DNA sequence for GC07M144850 Gene

Proteins for GC07M144850 Gene

Post-translational modifications for GC07M144850 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GC07M144850 Gene

Domains & Families for GC07M144850 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GC07M144850 Gene

Function for GC07M144850 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GC07M144850 Gene

Localization for GC07M144850 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GC07M144850 Gene

Pathways & Interactions for GC07M144850 Gene

SuperPathways for GC07M144850 Gene

No Data Available

Interacting Proteins for GC07M144850 Gene

Gene Ontology (GO) - Biological Process for GC07M144850 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GC07M144850 Gene

Drugs & Compounds for GC07M144850 Gene

No Compound Related Data Available

Transcripts for GC07M144850 Gene

fRNAdb Secondary structures for GC07M144850 Gene

  • FR224980
  • FR048166

Alternative Splicing Database (ASD) splice patterns (SP) for GC07M144850 Gene

No ASD Table

Relevant External Links for GC07M144850 Gene

GeneLoc Exon Structure for
GC07M144850

No data available for mRNA/cDNA for GC07M144850 Gene

Expression for GC07M144850 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GC07M144850 Gene

Orthologs for GC07M144850 Gene

No data available for Orthologs and Evolution for GC07M144850 Gene

Paralogs for GC07M144850 Gene

No data available for Paralogs for GC07M144850 Gene

Variants for GC07M144850 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for GC07M144850 Gene

Disorders for GC07M144850 Gene

No disorders were found for GC07M144850 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for GC07M144850 Gene

Publications for GC07M144850 Gene

  1. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C … Chen R (Nucleic acids research 2005) 1
  2. Transcription: surprising role for an elusive small nuclear RNA. (PMID: 11864590) Blencowe BJ (Current biology : CB 2002) 1
  3. Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function. (PMID: 1646389) Wassarman DA … Steitz JA (Molecular and cellular biology 1991) 1

Products for GC07M144850 Gene

Sources for GC07M144850 Gene

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