Aliases for GC Gene
External Ids for GC Gene
Previous GeneCards Identifiers for GC Gene
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
GeneCards Summary for GC Gene
GC (Group-Specific Component (Vitamin D Binding Protein)) is a Protein Coding gene. Diseases associated with GC include hepatic encephalopathy and acute liver failure. Among its related pathways are Metabolism and BMAL1-CLOCK,NPAS2 activates circadian gene expression. GO annotations related to this gene include actin binding and vitamin transporter activity. An important paralog of this gene is AFM.
UniProtKB/Swiss-Prot for GC Gene
Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.