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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GBX1 Gene

protein-coding   GIFtS: 44
GCID: GC07M150845

Gastrulation Brain Homeobox 1

(Previous name: gastrulation brain homeo box 1)
  Search for GBX1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Gastrulation Brain Homeobox 11 2
Gastrulation And Brain-Specific Homeobox Protein 12 3
Gastrulation Brain Homeo Box 11
Huh-172
Homeobox Protein GBX-12

External Ids:    HGNC: 41851   Entrez Gene: 26362   Ensembl: ENSG000001649007   OMIM: 6033545   UniProtKB: Q145493   

Export aliases for GBX1 gene to outside databases

Previous GC identifers: GC07U990039 GC07M149093 GC07M150160 GC07M150237 GC07M150283 GC07M150476 GC07M144657


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for GBX1 Gene: 
GBX1 (gastrulation brain homeobox 1) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is MNX1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007914.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GBX1 gene promoter:
         HNF-4alpha2   HNF-4alpha1   NF-AT   NF-AT4   NF-AT2   POU2F1   POU2F1a   NF-AT3   NF-AT1   ATF   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for GBX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GBX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1   Ensembl cytogenetic band:  7q36.1   HGNC cytogenetic band: 7q36.1

GBX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GBX1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M150845:  view genomic region     (about GC identifiers)

Start:
150,845,676 bp from pter      End:
150,871,832 bp from pter
Size:
26,157 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 150,175,196-150,194,388     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GBX1_HUMAN, Q14549 (See protein sequence)
Recommended Name: Homeobox protein GBX-1  
Size: 363 amino acids; 37629 Da
Subcellular location: Nucleus (By similarity)
1 PDB 3D structure from and Proteopedia for GBX1:
2M34 (3D)    

Explore the universe of human proteins at neXtProt for GBX1: NX_Q14549

Explore proteomics data for GBX1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q14549

  • GBX1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GBX1 Protein Expression
    REFSEQ proteins: NP_001092304.1  
    ENSEMBL proteins: 
     ENSP00000297537  

    Human Recombinant Protein Products for GBX1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
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    OriGene Protein Over-expression Lysate for GBX1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for GBX1
    GenScript Custom Purified and Recombinant Proteins Services for GBX1
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GBX1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000228nuclear chromosome NAS--

    GBX1 for ontologies           About GeneDecksing



    GBX1 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for GBX1 

    Assay Products for GBX1: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for GBX1 
    Cloud-Clone Corp. CLIAs for GBX1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    4 InterPro protein domains:
     IPR020479 Homeobox_metazoa
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q14549

    ProtoNet protein and cluster: Q14549

    1 Blocks protein domain: IPB000047 Lambda and other repressor helix-turn-helix signature

    UniProtKB/Swiss-Prot: GBX1_HUMAN, Q14549
    Similarity: Contains 1 homeobox DNA-binding domain


    GBX1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for GBX1:
    mouse telencephalon expressed Gbx homolog 1,gastrulation and brain speciifc-2,homeo domain encoding gene

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity NAS--
    GO:0043565sequence-specific DNA binding IEA--
         
    GBX1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for GBX1:
     G0/1 arrest  Increased G1 DNA content 

         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Gbx1):
     behavior/neurological  nervous system  normal 

    GBX1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Gbx1tm1.1Stwt for GBX1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for GBX1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GBX1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GBX1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GBX1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GBX1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate GBX1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GBX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GBX1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for GBX1
    Sirion Biotech Customized adenovirus for overexpression of GBX1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for GBX1 (see all 6)
    OriGene ORF clones in mouse, rat for GBX1
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    GenScript: all cDNA clones in your preferred vector: GBX1 (NM_001098834)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GBX1
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                         Customized lentivirus expression plasmids for stable overexpression of GBX1 

    Cell Line
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    Search LifeMap BioReagents cell lines for GBX1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GBX1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GBX1

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent NAS--

    GBX1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GBX1

    Search CenterWatch for drugs/clinical trials and news about GBX1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GBX1 gene: 
    NM_001098834.2  

    Unigene Cluster for GBX1:

    Gastrulation brain homeobox 1
    Hs.647114  [show with all ESTs]
    Unigene Representative Sequence: NM_001098834
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297537(uc011kvg.2) ENST00000475831
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GBX1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate GBX1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GBX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GBX1
    Clone
    Products:
         
    OriGene clones in human, mouse for GBX1 (see all 6)
    OriGene ORF clones in mouse, rat for GBX1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GBX1 (NM_001098834)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GBX1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GBX1
    Sirion Biotech Customized lentivirus for stable overexpression of GBX1 
                         Customized lentivirus expression plasmids for stable overexpression of GBX1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for GBX1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GBX1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GBX1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GBX1

    1 DOTS entry:

    DT.121044377 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GBX1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAACAGGTT
    GBX1 Expression
    About this image


    See GBX1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GBX1

    SOURCE GeneReport for Unigene cluster: Hs.647114
        SABiosciences Custom PCR Arrays for GBX1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for GBX1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GBX1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GBX1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GBX1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GBX1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GBX1 gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gbx11 , 5 gastrulation brain homeobox 11, 5 89.2(n)1
    92.18(a)1
      5 (11.93 cM)5
    2310441  NM_015739.21  NP_056554.11 
     245027575 
    chicken
    (Gallus gallus)
    Aves GBX11 gastrulation brain homeobox 1 76.64(n)
    79.13(a)
      395377  XM_003640629.1  XP_003640677.1 
    zebrafish
    (Danio rerio)
    Actinopterygii gbx11 gastrulation brain homeobox 1 66.88(n)
    71.06(a)
      142985  NM_174861.2  NP_777286.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta unpg6
    CG156966
    --
    26(a)
    21(a)
    1 ↔ many
    possible ortholog
    2R(5082719-5087377)
    3R(16672833-16673372)
    worm
    (Caenorhabditis elegans)
    Secernentea ceh-126
    ceh-626
    Uncharacterized homeobox protein R06F6.6
    26(a)
    10(a)
    possible ortholog
    possible ortholog
    I(5840289-5841888)
    II(10805394-10809992)


    ENSEMBL Gene Tree for GBX1 (if available)
    TreeFam Gene Tree for GBX1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GBX1 gene
    MNX12  EVX12  MEOX12  EVX22  MEOX22  GBX22  
    8 SIMAP similar genes for GBX1 using alignment to 2 protein entries:     GBX1_HUMAN (see all proteins):
    HMX2    HOX B6    HOXA4    HOXB1    HHEX    HOXC13
    GBX2    HOXD11

    GBX1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    281/338 SNPs in GBX1 are shown (see all 338)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1472905691,2
    C--150845650(+) CCCTCA/GCCTTC 1 -- ds50010--------
    rs2020465641,2
    --150845717(+) GCTCCA/GCACAG 2 R W mis10--------
    rs2015667611,2
    C--150845722(+) GCACAG/ACAAAC 2 /A /V mis11Minor allele frequency- A:0.00EU 1323
    rs1995154741,2
    C--150845788(+) CAGAAC/TGGCTG 2 H R mis11Minor allele frequency- T:0.00EU 1323
    rs751762551,2
    C,F--150845853(+) ATCTTG/TACCTG 2 V syn11Minor allele frequency- T:0.03EA 120
    rs2014173191,2
    C--150845886(+) TGGGCG/AATCTG 2 /I syn11Minor allele frequency- A:0.00EU 1323
    rs2007853191,2
    --150845912(+) GCTCAA/GGTATT 2 L syn10--------
    rs2003332321,2
    C--150845977(+) TGCGGC/TGCCGT 2 H R mis10--------
    rs2013951691,2
    C--150846022(+) TCACCA/GGTGCC 2 P L mis10--------
    rs69707681,2
    C,H--150846058(+) TTCCCT/CTTAGC 2 /K /R mis1 ese35Minor allele frequency- C:0.00NS EA NA 416
    rs2001199341,2
    --150846083(+) CAGAAA/GAGCCC 2 L F mis10--------
    rs1924790271,2
    C--150846105(+) GCAGAA/CCTGTC 2 R S mis10--------
    rs119757991,2,4
    C,F,H--150846188(+) TGATGC/TCTCCA 2 T A mis18Minor allele frequency- T:0.05NS EA NA WA 600
    rs1410409621,2
    --150846322(+) GGGGGA/GTTGGG 1 -- int10--------
    rs1845064551,2
    --150846415(+) TGGAAC/TGGGAA 1 -- int10--------
    rs1877885021,2
    --150846630(+) CAGAGC/TCAGGC 1 -- int10--------
    rs1170937031,2
    C,F--150846699(+) AGCCAC/TTGGGG 1 -- int11Minor allele frequency- T:0.01NA 120
    rs1418686701,2
    C--150846765(+) GCTCA-/AGCCTT 1 -- int10--------
    rs1918450871,2
    --150846886(+) ATTTCC/TATGGC 1 -- int10--------
    rs1448757601,2
    --150847023(+) CCCAGC/TCAAGG 1 -- int10--------
    rs1843901221,2
    --150847400(+) AACAAA/GTCAAA 1 -- int10--------
    rs1891934881,2
    --150847543(+) ATCGGC/TCACAT 1 -- int10--------
    rs1508266621,2
    --150847616(+) TCAGGA/GCACGG 1 -- int10--------
    rs1819218801,2
    --150847619(+) GGGCAC/TGGGGA 1 -- int10--------
    rs1857248011,2
    --150847691(+) AGCTTC/TCTGGT 1 -- int10--------
    rs1131926711,2
    C,F--150847711(+) CAGCAT/CACCCC 1 -- int11Minor allele frequency- C:0.00CSA 1
    rs1906807681,2
    --150847723(+) CCCCAC/TCCCCT 1 -- int10--------
    rs1806871391,2
    --150847726(+) CACCCA/CCTGCC 1 -- int10--------
    rs10017601,2
    C,F,A,H--150847749(+) CCCTCG/ACAGGT 1 -- int119Minor allele frequency- A:0.42NS EA NA WA CSA 1278
    rs1861764961,2
    --150847795(+) ATTGAC/TATTTT 1 -- int10--------
    rs1899752211,2
    --150847980(+) CCTGGC/TTAATT 1 -- int10--------
    rs1813065871,2
    --150848129(+) TTTCCC/TTAGTG 1 -- int10--------
    rs1140534181,2
    --150848384(+) GCCCAC/GCATCA 1 -- int10--------
    rs1857821281,2
    --150848433(+) AATTCA/GCCCCT 1 -- int10--------
    rs1499823711,2
    --150848480(+) TCTCAC/TCCCTA 1 -- int10--------
    rs47260001,2
    C,F,A,H--150848537(+) CCTTCA/GTTTCA 1 -- int126Minor allele frequency- N:0.00NS EA NA WA 2980
    rs1160090761,2
    F--150848604(+) CCAAAT/CTGAAC 1 -- int11Minor allele frequency- C:0.01WA 118
    rs1452692621,2
    --150848715(+) ACCTCA/GATGCC 1 -- int10--------
    rs746560451,2
    C,F--150848732(+) TTACTC/TCTCTC 1 -- int11Minor allele frequency- T:0.16EA 120
    rs1412900421,2
    --150848975(+) TCTTGC/TACTAG 1 -- int10--------
    rs1906802021,2
    --150849097(+) TTGGTC/TCATTT 1 -- int10--------
    rs64641321,2
    C,F,A,H--150849164(+) GTGAAA/GGTAGG 1 -- int136Minor allele frequency- N:0.00NS EA NA WA CSA 3409
    rs1441052001,2
    --150849279(+) AGAAAC/TGATTT 1 -- int10--------
    rs125364831,2
    H--150849341(+) CTTTCC/GTAAGC 1 -- int1 trp34Minor allele frequency- G:0.00NS EA 418
    rs562670911,2
    C,F--150849353(+) TCTCCG/AACGAT 1 -- int13Minor allele frequency- A:0.18WA CSA 122
    rs1840139601,2
    --150849364(+) ATTCCC/TCACAA 1 -- int10--------
    rs1464726251,2
    --150849607(+) AAAAGA/TATAAC 1 -- int10--------
    rs1411248351,2
    --150849994(+) CATGAC/TATTGA 1 -- int10--------
    rs1432077511,2
    --150850148(+) CCAAGG/TCAGGT 1 -- int10--------
    rs1886063321,2
    --150850194(+) AGAAAC/TAGCAG 1 -- int10--------
    rs608490781,2
    C,F--150850209(+) ATTAAA/TTGATG 1 -- int13Minor allele frequency- T:0.17WA CSA 122
    rs793673671,2
    C,F--150850210(+) TTAAAT/CGATGA 1 -- int11Minor allele frequency- C:0.16EA 120
    rs1482724361,2
    --150850252(+) GAGAAA/GGGAGA 1 -- int10--------
    rs1922983491,2
    --150850279(+) AATCAA/GGGGAA 1 -- int10--------
    rs69479881,2
    C,F,A,H--150850472(+) AGTGCG/AATCCT 1 -- int135Minor allele frequency- A:0.44NS EA NA WA CSA 3279
    rs1401236401,2
    --150850487(+) AATGTA/GGAAAT 1 -- int10--------
    rs354026641,2
    C--150850637(+) AAATC-/TTTTTT 1 -- int12Minor allele frequency- T:0.25NA 4
    rs1824467261,2
    --150850731(+) CTGGTC/TTCAAG 1 -- int10--------
    rs1126504791,2
    C--150850779(+) TAGGCG/ACACAC 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs14306221,2
    C,F,A--150850835(+) tgcagA/Tgttgg 1 -- int1 tfbs313Minor allele frequency- T:0.41NA WA CSA EA 511
    rs1140197151,2
    C,F--150850872(+) CTCAAA/GCTTCT 1 -- int11Minor allele frequency- G:0.07WA 118
    rs1147698861,2
    F--150851293(+) TGTCTC/TGAAAA 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1868400231,2
    --150851360(+) ATAAAC/TAAATA 1 -- int10--------
    rs1136833121,2
    C,F--150851372(+) GAATTA/TAAAAT 1 -- int12Minor allele frequency- T:0.04CSA WA 120
    rs47253941,2
    C,F,A,H--150851566(+) TATTAT/CTGGTA 1 -- int121Minor allele frequency- C:0.33NA NS EA WA 2480
    rs1163971111,2
    C,F--150851595(+) GTTTCC/TAGCTT 1 -- int11Minor allele frequency- T:0.08WA 118
    rs1917116671,2
    --150851608(+) TCCCTA/GTGGTT 1 -- int10--------
    rs1502935451,2
    --150851718(+) GGATGC/TTATTA 1 -- int10--------
    rs1843456301,2
    --150851767(+) ACTTGC/TAGAGT 1 -- int10--------
    rs1173190251,2
    F--150851783(+) TCAAGG/AGCATT 1 -- int11Minor allele frequency- A:0.02EA 120
    rs1874947701,2
    --150851825(+) CAGGAA/GACGTG 1 -- int10--------
    rs1920022681,2
    --150851839(+) GCATGG/TGGCCT 1 -- int10--------
    rs1130896531,2
    C,F--150851911(+) CAGTTC/TGGGCT 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1853018481,2
    --150852033(+) GGAGGA/GGGAGG 1 -- int10--------
    rs1472991461,2
    --150852099(+) AGCCCC/TTGTGC 1 -- int10--------
    rs1392001641,2
    C--150852129(+) TACTGC/TAGCTC 1 -- int10--------
    rs763673641,2
    C,F--150852144(+) TGTTAT/CCACCG 1 -- int11Minor allele frequency- C:0.03NA 120
    rs744737081,2
    C--150852148(+) ATCACC/TGTAGG 1 -- int10--------
    rs1448640141,2
    C--150852300(+) GGACAA/GTGAAT 1 -- int10--------
    rs1485797901,2
    C--150852322(+) TTTCAC/TAGGCC 1 -- int10--------
    rs1159144741,2
    F--150852344(+) TCCCTG/CAATCC 1 -- int11Minor allele frequency- C:0.01WA 118
    rs69790151,2
    C,F,A,H--150852393(+) ACAGGA/TCATTC 1 -- int125Minor allele frequency- N:0.00EA NA NS WA CSA 1784
    rs1174436711,2
    C,F--150852472(+) ATTATT/CTCTCT 1 -- int11Minor allele frequency- C:0.03NA 120
    rs1428281191,2
    --150852575(+) CCATTA/GTGCTC 1 -- int10--------
    rs1902797471,2
    --150852586(+) CTACTC/TCTGCC 1 -- int10--------
    rs1426010951,2
    C--150852631(+) CATTT-/TCTCTCT 1 -- int10--------
    rs1824499361,2
    --150853159(+) TCTTAC/TCAAAT 1 -- int10--------
    rs1460497061,2
    --150853220(+) AATCCC/TAGCAC 1 -- int10--------
    rs1400794221,2
    --150853281(+) GCCTGA/GCCAAC 1 -- int10--------
    rs726173601,2
    C,F--150853449(+) GTTTGG/AGCGAC 1 -- int11Minor allele frequency- A:0.08EA 120
    rs3714301511,2
    C--150853504(+) AAAAA-/CGAAAAA 1 -- int10--------
    rs1842626801,2
    --150853556(+) TACCAC/GAGAGT 1 -- int10--------
    rs748946671,2
    F--150853599(+) TTCTCA/GGAGAA 1 -- int11Minor allele frequency- G:0.03WA 118
    rs47260011,2
    H--150853688(+) CCTGAG/AACAAA 1 -- int1 tfbs34Minor allele frequency- A:0.00NS EA 418
    rs1436521641,2
    C--150854035(+) CAACTA/GTACTC 1 -- int10--------
    rs344795481,2
    C--150854072(+) AAAAAA/-GTGTA 1 -- int11Minor allele frequency- -:0.00NA 2
    rs1882611291,2
    --150854144(+) CTTTGC/GGAGGC 1 -- int10--------
    rs795494091,2
    C--150854168(+) TCAGGA/GGGTCA 1 -- int10--------
    rs1811889431,2
    --150854304(+) CTTGAA/GCCCGG 1 -- int10--------
    rs1856256631,2
    C--150854442(+) ACAACC/TTTCTC 1 -- int10--------
    rs1410612001,2
    C--150854456(+) CATTCC/TTCATA 1 -- int10--------
    rs1497140091,2
    C--150854501(+) AAAGCC/TTCACT 1 -- int10--------
    rs1121520301,2
    C--150854510(+) CTGAGC/TGATGG 1 -- int12Minor allele frequency- T:0.07CSA WA 120
    rs1901367591,2
    --150854629(+) CAAAGG/TATTTC 1 -- int10--------
    rs97850171,2
    C,F,H--150854637(+) TTCCTT/CTCAGT 1 -- int16Minor allele frequency- C:0.03NS EA WA 534
    rs603162211,2
    C--150854647(+) TATTTC/ATTCCT 1 -- int13Minor allele frequency- A:0.17WA CSA 122
    rs1456623961,2
    --150854751(+) TCCCCC/TTTTTG 1 -- int10--------
    rs1814696861,2
    --150854773(+) TACCCA/GCTTCC 1 -- int10--------
    rs1488947091,2
    --150854902(+) ATCTCC/TCTGGA 1 -- int10--------
    rs1870462561,2
    --150854926(+) CTAGCA/GAATTA 1 -- int10--------
    rs1177605361,2
    --150854970(+) CTCAGG/ATCCTA 1 -- int11Minor allele frequency- A:0.01EA 120
    rs726173611,2
    C,F--150855033(+) TCTCTT/CACCTC 1 -- int11Minor allele frequency- C:0.20EA 120
    rs1173041061,2
    F--150855232(+) CGAAGA/GGTTCT 1 -- int11Minor allele frequency- G:0.01EA 120
    rs14306241,2
    C,F,H--150855244(+) ACTAAA/GTACGA 1 -- int135Minor allele frequency- G:0.43NS EA NA WA CSA 3336
    rs1918328091,2
    --150855556(+) TTTTTG/TTTTTA 1 -- int10--------
    rs737274851,2
    C,F--150855583(+) AACAGG/ACCCTA 1 -- int12Minor allele frequency- A:0.12WA 120
    rs1841766251,2
    --150855662(+) AAACCA/GAAAAG 1 -- int10--------
    rs1853109841,2
    --150855706(+) ACCCCC/TAATTA 1 -- int10--------
    rs737274861,2
    C--150855745(+) TCCCCG/AAATAA 1 -- int12Minor allele frequency- A:0.10WA 120
    rs1378559931,2
    --150855793(+) CCAGAA/GATATT 1 -- int10--------
    rs1900209541,2
    --150855801(+) ATTTGC/TCCTTT 1 -- int10--------
    rs69579561,2
    H--150855846(+) CCTAGT/CAACAA 1 -- int14Minor allele frequency- C:0.00NS EA 416
    rs734767991,2
    C--150855952(+) GCTGCA/GCAAAT 1 -- int14Minor allele frequency- G:0.21WA CSA 123
    rs1420720061,2
    C--150856068(+) AAGTGC/TGCCAC 1 -- int10--------
    rs1823364241,2
    --150856115(+) GCTTGC/TTCCTT 1 -- int10--------
    rs344073781,2
    C,F--150856173(+) CTGAAT/-TTTTT 1 -- int13Minor allele frequency- -:0.33NA CSA 6
    rs579780001,2
    C,F--150856226(+) GAGTGT/CAGTGG 1 -- int11Minor allele frequency- C:0.20EA 120
    rs747170111,2
    C,F--150856268(+) CCAGGC/TTCAAG 1 -- int15Minor allele frequency- T:0.14NA WA CSA EA 244
    rs1119870101,2
    C--150856357(+) TTGTAG/AAGACG 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1459023311,2
    --150856393(+) GTCTCA/GAACTC 1 -- int10--------
    rs802739151,2
    C,F--150856470(+) TTTTTG/ATTGTT 1 -- int11Minor allele frequency- A:0.07EA 120
    rs1387196531,2
    C--150856620(+) ATACAC/TACCAC 1 -- int10--------
    rs1415362101,2
    --150856764(+) AGGACA/GAGACT 1 -- int10--------
    rs1869990061,2
    --150856780(+) CTAATA/GTCAGC 1 -- int10--------
    rs1929579461,2
    --150856940(+) CTACCA/GTCTTT 1 -- int10--------
    rs737274881,2
    C,F--150856966(+) CTCTCG/ATTTAA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1833036071,2
    --150857026(+) GAAGAA/CAAGCC 1 -- int10--------
    rs777226771,2
    F--150857128(+) GAAAAG/CTATAG 1 -- int12Minor allele frequency- C:0.08NA 122
    rs1157341421,2
    F--150857346(+) TAATTC/TATAGA 1 -- int11Minor allele frequency- T:0.01WA 118
    rs1169587681,2
    C,F--150857486(+) CCATTA/GCTTCT 1 -- int11Minor allele frequency- G:0.03NA 120
    rs354711301,2
    C--150857556(+) CAGAAA/GTATTT 1 -- int10--------
    rs1887975661,2
    --150857746(+) CTGAAG/TTCAAC 1 -- int10--------
    rs18209681,2
    H--150857855(-) GCTTAG/AAGTAC 1 -- int14Minor allele frequency- A:0.00NS EA 418
    rs560280911,2
    C,F--150857906(+) TTTCCC/TGCCTC 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1930575661,2
    --150857907(+) TTCCCA/GCCTCT 1 -- int10--------
    rs1858737181,2
    --150857963(+) TACCTG/TGCATA 1 -- int10--------
    rs581209761,2
    C,F--150857983(+) GTCCTT/CTTCAC 1 -- int12Minor allele frequency- C:0.02WA 120
    rs1460631001,2
    --150857998(+) TCAGAC/TACAAA 1 -- int10--------
    rs1400452581,2
    --150858209(+) TTCCTA/GTTGTA 1 -- int10--------
    rs47253951,2
    C,F,A--150858271(+) TTCCAA/GTTAAA 1 -- int112Minor allele frequency- N:0.00EA NA WA CSA 582
    rs1419557981,2
    --150858337(+) ACTCAC/TGCCTG 1 -- int10--------
    rs1457852411,2
    C--150858542(+) ATCCA-/GGGGGTTC 1 -- int10--------
    rs1463413261,2
    --150858602(+) TGAACA/GCTTTC 1 -- int10--------
    rs1116458311,2
    C,F--150859180(+) ACAACT/GCCTAA 1 -- int12Minor allele frequency- G:0.07CSA WA 120
    rs1485304891,2
    C--150859264(+) TGACTA/GTATGC 1 -- int10--------
    rs779641581,2
    F--150859361(+) TCCACG/ATCATA 1 -- int11Minor allele frequency- A:0.05WA 118
    rs1421757071,2
    --150859521(+) CTCCTA/TGGAAG 1 -- int10--------
    rs787232171,2
    C,F--150859533(+) CTCCCC/TGGTCT 1 -- int12Minor allele frequency- T:0.07CSA WA 120
    rs1881118811,2
    --150859807(+) CTAAGC/TTTTTG 1 -- int10--------
    rs346855501,2
    C--150859892(+) TGCCTT/-TTTTT 1 -- int11Minor allele frequency- -:0.50NA 2
    rs1118150111,2
    C--150859892(+) CTGCC-/T/TTT 
            
    TTTTT
    2 -- int1 cds11CSA 2
    rs1511888591,2
    --150860055(+) AGCCCA/GGCTAA 1 -- int10--------
    rs1911211191,2
    --150860067(+) TTTGTA/TTTTTT 1 -- int10--------
    rs7684031,2
    C,F,A,H--150860246(-) AAGGAT/CGCTAT 1 -- int1108Minor allele frequency- C:0.44NS EA PA EU CA WA NA CSA 7033
    rs774344851,2
    C,F--150860330(+) CCAGAG/ACTCAC 1 -- int12Minor allele frequency- A:0.08NA EA 240
    rs1836257701,2
    --150860383(+) TAAGAC/TAGAAT 1 -- int10--------
    rs1884302271,2
    --150860439(+) TTATTC/TCTAAT 1 -- int10--------
    rs1392028131,2
    --150860448(+) ATACAC/TTGAGG 1 -- int10--------
    rs1814149141,2
    --150860528(+) GATCCA/GTCATG 1 -- int10--------
    rs7678661,2
    C,F,A,H--150860621(+) AAAATA/GACACT 1 -- int112Minor allele frequency- G:0.34NS EA NA WA 892
    rs772009331,2
    F--150860772(+) TGTGGC/TTAATA 1 -- int11Minor allele frequency- T:0.01NA 120
    rs1866790671,2
    --150860890(+) TCTCCC/TCTTTA 1 -- int10--------
    rs737274891,2
    C,F--150860993(+) TTCTAC/TCCAAT 1 -- int12Minor allele frequency- T:0.15WA 120
    rs1499460121,2
    --150861060(+) CAAGTA/CATAAC 1 -- int10--------
    rs1476382021,2
    --150861061(+) AAGTCA/GTAACA 1 -- int10--------
    rs1158113431,2
    F--150861070(+) CAAAGT/GTCCTT 1 -- int11Minor allele frequency- G:0.02WA 118
    rs624896311,2
    C,F--150861098(+) TAGTAG/CAGAAT 1 -- int12Minor allele frequency- C:0.08NA EA 240
    rs1486501691,2
    C--150861130(+) AAATT-/AAAAAA 1 -- int10--------
    rs1904316831,2
    --150861140(+) AAAATA/GGTCCC 1 -- int10--------
    rs283770771,2
    C,F--150861227(+) CAGTTG/ATAAAA 1 -- int15Minor allele frequency- A:0.08WA CSA NA EA 362
    rs1420055661,2
    --150861287(+) CACACA/GAGGAA 1 -- int10--------
    rs1820743051,2
    --150861381(+) GCAGAA/GAGCTC 1 -- int10--------
    rs801445321,2
    C,F--150861596(+) GAAGCG/ATGTTT 1 -- int12Minor allele frequency- A:0.07CSA WA 120
    rs1863110211,2
    --150861667(+) TGTTTA/CTTCTG 1 -- int10--------
    rs1457429211,2
    --150861763(+) TATTCC/TAGCAC 1 -- int10--------
    rs2004911231,2
    --150861849(+) GAACA-/ACACAAA 1 -- int10--------
    rs715335211,2
    C--150861863(+) CCCTCTT/-TTTTT 1 -- int11Minor allele frequency- -:0.50NA 2
    rs1910564261,2
    --150862066(+) CACACA/GCACAC 1 -- int10--------
    rs1821671771,2
    --150862067(+) ACACAA/CACACA 1 -- int10--------
    rs1853798171,2
    --150862075(+) ACACAA/GACACA 1 -- int10--------
    rs801558921,2
    C,F--150862102(+) CACACT/CCACTC 1 -- int11Minor allele frequency- C:0.19EA 120
    rs1911185161,2
    --150862293(+) TTCCTC/TTCTTT 1 -- int10--------
    rs624896321,2
    C,F--150862362(+) ACATAT/CAGGTC 1 -- int17Minor allele frequency- C:0.20NA CSA WA EA 366
    rs1478065771,2
    --150862406(+) ACAAAC/TTGCTT 1 -- int10--------
    rs726173621,2
    C,F--150862436(+) ATATGC/GCCCTA 1 -- int11Minor allele frequency- G:0.19EA 120
    rs1488411771,2
    --150862652(+) CTCCCA/GCCCTG 1 -- int10--------
    rs753826761,2
    C,F--150862665(+) CCCTTT/CTATCT 1 -- int11Minor allele frequency- C:0.08WA 118
    rs757651711,2
    C,F--150862765(+) GTCTTC/TCTGAT 1 -- int11Minor allele frequency- T:0.07NA 120
    rs1833822461,2
    --150862800(+) AACAGA/CTGAAT 1 -- int10--------
    rs749658001,2
    C,F--150863006(+) GCTCCC/TAGGCC 1 -- int12Minor allele frequency- T:0.07CSA WA 120
    rs1437755341,2
    --150863058(+) GTTGAG/TCAGAA 1 -- int10--------
    rs734786051,2
    C--150863156(+) AAATTG/ATATAA 1 -- int14Minor allele frequency- A:0.12WA NA 242
    rs1883643141,2
    --150863751(+) TTGTAG/TCTTGT 1 -- int10--------
    rs583040551,2
    C,F--150864057(+) CAGGTG/TAACCG 1 -- int16Minor allele frequency- T:0.05NA WA EA EU 1419
    rs2017563101,2
    C--150864117(+) AAAGTA/CTCTGA 2 E D mis10--------
    rs2005454131,2
    C--150864185(+) CTCATC/TAGCTT 2 N D mis10--------
    rs1931950021,2
    --150864234(+) TTGTTG/TCGGGC 2 R syn10--------
    rs132419781,2
    C,F--150864240(+) CGGGCG/CGCAGT 2 /A syn13Minor allele frequency- C:0.35WA NA EA 358
    rs1419408331,2
    C--150864913(+) GCCGCC/TGCCGC 1 -- us2k10--------
    rs1829124521,2
    C--150865067(+) GCCGAC/GGAGAA 1 -- us2k10--------
    rs1140949101,2
    F--150865075(+) GAAGGC/TGGCGG 1 -- us2k11Minor allele frequency- T:0.15WA 118
    rs782463081,2
    C,F--150865112(+) CCACCC/TAGTCC 1 -- us2k11Minor allele frequency- T:0.16EA 120
    rs1451889141,2
    C--150865124(+) CCCCCA/C/TCAACT 1 -- us2k10--------
    rs1469316111,2
    C--150865149(+) GGGCT-/CCC   
      G
    /CCGC
    CCGGC
    1 -- us2k10--------
    rs721697281,2
    C--150865150(+) GGCTC-/CCGC  
            
    CGGCT
    1 -- us2k10--------
    rs1390046881,2
    --150865204(+) GGGCCA/GAGCGT 1 -- us2k10--------
    rs1875458611,2
    --150865260(+) CAGGCA/GGCGGG 1 -- us2k10--------
    rs1416457041,2
    C--150865263(+) GCGGC-/GGGGCC 1 -- us2k10--------
    rs1433628491,2
    C--150865383(+) GTGGC-/GGGGTCC 1 -- us2k10--------
    rs1419872311,2
    --150865597(+) ATTGGC/TTCTTC 1 -- us2k10--------
    rs780191611,2
    C,F--150865662(+) GCCTCG/AGTGGG 1 -- us2k11Minor allele frequency- A:0.14EA 120
    rs1925841341,2
    --150865665(+) TCGGTG/TGGTAA 1 -- us2k10--------
    rs1835028691,2
    --150865826(+) TTCCCA/GTCTCT 1 -- us2k10--------
    rs1462928171,2
    --150865896(+) TCTTGG/TCTGTC 1 -- us2k10--------
    rs1895827481,2
    --150865988(+) CCAGCA/GCCGCT 1 -- us2k10--------
    rs731696241,2
    C--150866134(+) TCCCCA/CCTTCT 1 -- us2k10--------
    rs1495770991,2
    --150866135(+) CCCCCC/TTTCTG 1 -- us2k10--------
    rs1926277751,2
    --150866158(+) GGTGGC/TGCCTT 1 -- us2k10--------
    rs1445515931,2
    --150866208(+) GAGTTA/GTCAAT 1 -- us2k10--------
    rs69787811,2
    A--150866281(+) ACAAGA/GCAGGC 1 -- us2k10--------
    rs737274911,2
    C--150866443(+) TAGGAC/AGATGC 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1484654821,2
    --150866447(+) AAGATA/GCAGTC 1 -- us2k10--------
    rs102550451,2
    H--150866464(+) GGGGAA/GGTGAT 1 -- us2k15Minor allele frequency- G:0.00NS EA NA 416
    rs1452307721,2
    --150866487(+) AGGACA/GAAAAC 1 -- us2k10--------
    rs1896312041,2
    --150866502(+) ACAAGA/TTCCAG 1 -- us2k10--------
    rs47260031,2
    C,F--150866516(+) TGCCCG/AGCCAA 1 -- us2k15Minor allele frequency- A:0.19NA WA EA 362
    rs748279101,2
    C,F--150866852(+) AGAGGT/CGCCTT 1 -- us2k11Minor allele frequency- C:0.29WA 118
    rs571866291,2
    ----150851353(+) AAAAAC/TGATAA 1 -- int10--------
    rs3721581781,2
    ----150864104(+) GGGCAG/TACTTG 2 M L mis10--------
    rs3771376601,2
    ----150857077(+) GCATGA/CTCTTA 1 -- int10--------
    rs782997931,2
    ----150860696(+) TAATGC/TTGAAA 1 -- int10--------
    rs3695506521,2
    ----150847993(+) GTTTA-/TTTTTT 1 -- int10--------
    rs665990771,2
    ----150861884(+) TTTTG-/TT/TTT
            
    CTTTC
    2 -- int1 cds10--------
    rs7678651,2
    ----150860697(+) AATGTG/TGAAAT 1 -- int10--------
    rs3709708051,2
    ----150846063(+) TTTAGC/TTTCGG 2 K syn10--------
    rs346351191,2
    ----150847873(+) TGGAGC/TATAGT 1 -- int10--------
    rs3764672971,2
    ----150854473(+) TTTCTC/TGTATA 1 -- int10--------
    rs3707881981,2
    ----150861966(+) AAACTC/TTTAAA 1 -- int10--------
    rs1469674561,2
    ----150866560(+) AGTGAC/TATTTG 1 -- us2k10--------
    rs3709560651,2
    ----150866513(+) GATTGC/GCCGGC 1 -- us2k10--------
    rs3765667701,2
    ----150845683(+) AGGGCC/TGGGCC 2 Q R mis10--------
    rs3683138781,2
    ----150854779(+) CTTCC-/TTTAGG 1 -- int10--------
    rs3702732461,2
    ----150853664(+) TAACAA/TCTACT 1 -- int10--------
    rs3744882681,2
    ----150847463(+) TAGTCA/GGCTCC 1 -- int10--------
    rs1915064251,2
    ----150866068(+) AGGAGC/TGCTGA 1 -- us2k10--------
    rs344865731,2
    ----150859939(+) CCCAG-/GCTGGA 1 -- int10--------
    rs2013063491,2
    ----150860090(+) GTTTCA/TCCATG 1 -- int10--------
    rs3755228421,2
    ----150864099(+) TTACCA/GGGCAG 2 P syn10--------
    rs3679150691,2
    ----150849913(+) GTTCAC/TACCTC 1 -- int10--------
    rs569477351,2
    ----150853498(+) AAAAA-/AAAAAA
            
    CGAAA
    1 -- int10--------
    rs3723053651,2
    ----150855332(+) ATCCAC/TCTAAT 1 -- int10--------
    rs3676505201,2
    ----150862560(+) GCCTGC/TTTACT 1 -- int10--------
    rs346013631,2
    ----150848155(+) CTTTT-/TCCACA 1 -- int10--------
    rs3750336661,2
    ----150848600(+) TGCCCC/TAATTG 1 -- int10--------
    rs171737171,2
    ----150863456(+) TCCAGC/TGTGTG 1 -- int13Minor allele frequency- T:0.01NA 138
    rs357640671,2
    ----150865151(+) GCTCC-/GCCC  
            
    GGCTA
    1 -- us2k10--------
    rs3696161921,2
    ----150853646(+) CAAACC/TTCACC 1 -- int10--------
    rs3698100121,2
    ----150864100(+) CA/GGCAGA 2 P L mis10--------
    rs3728191751,2
    ----150845301(+) GGTATC/TCCTGT 1 -- ds50010--------
    rs14306231,2
    ----150850997(+) ATTTAA/GAATAA 1 -- int1 tfbs30--------
    rs3747486241,2
    ----150858420(+) AGAGA-/TCTT  
            
    CTTTC
    1 -- int10--------
    rs2014024541,2
    ----150850636(+) TTTTT-/TCCTGA 1 -- int10--------
    rs3772779421,2
    ----150854038(+) CTGTAC/TTCCAG 1 -- int10--------
    rs354470871,2
    ----150845345(+) TTTGC-/CACAGA 1 -- ds50010--------
    rs3769967141,2
    ----150860245(+) CATAGC/TTCCTT 1 -- int10--------
    rs3735629081,2
    ----150845832(+) GCCCGC/TCGATT 2 R syn10--------
    rs609496831,2
    ----150849038(+) CTTTTA/TAAATT 1 -- int10--------
    rs353591811,2
    ----150847616(+) CAGGG-/GCACGG 1 -- int10--------
    rs3742615321,2
    ----150846010(+) TGACCA/CCTGCT 2 G V mis10--------
    rs3729885211,2
    ----150851396(+) TTGCAA/CTTGTT 1 -- int10--------
    rs3761104091,2
    ----150863562(+) ACGCA-/CCCCCC 1 -- int10--------

    HapMap Linkage Disequilibrium report for GBX1 (150845676 - 150871832 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for GBX1:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv7547n71CNV Loss21882294
    nsv831188CNV Loss17160897
    dgv7545n71CNV Loss21882294
    nsv889476CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GBX1 for disorders           About MalaCards
    OMIM gene information: 603354    OMIM disorders: --


    GBX1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): GBX1

    Export disorders for GBX1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GBX1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with GBX1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    2. Expression of a novel human homeobox-containing gene that maps to chromosome 7q36.1 in hematopoietic cells. (PubMed id 8097731)1, 2 Matsui T.... Kurosawa Y. (1993)
    3. The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans. (PubMed id 7903253)1, 3 Matsui T.... Kurosawa Y. (1993)
    4. cDNA cloning and expression of the human NOBOX gene in oocytes and ovarian follicles. (PubMed id 16597639)1 Huntriss J.... Picton H.M. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2636 HGNC: 4185 Ensembl:ENSG00000164900 euGenes: HUgn2636 ECgene: GBX1
    H-InvDB: GBX1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GBX1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GBX1 gene:
    Search GeneIP for patents involving GBX1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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