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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GBGT1 Gene

protein-coding   GIFtS: 56
GCID: GC09M136028

Globoside Alpha-1,3-N-Acetylgalactosaminyltransferase 1

Microbiology & Infectious Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Globoside Alpha-1,3-N-Acetylgalactosaminyltransferase 11 2     FS2 5
Forssman Glycolipid Synthetase (FS)1 2     A3GALNT2
Forssman Synthetase1 2     UNQ25132
Forssman Glycolipid Synthase-Like Protein2 3     EC 2.4.1.-3

External Ids:    HGNC: 204601   Entrez Gene: 263012   Ensembl: ENSG000001482887   OMIM: 6060745   UniProtKB: Q8N5D63   

Export aliases for GBGT1 gene to outside databases

Previous GC identifers: GC09M131305 GC09M133057 GC09M135018 GC09M105521


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GBGT1 Gene:
This gene encodes a member of the histo-blood group ABO gene family that encodes glycosyltransferases with related
but distinct substrate specificity. This protein plays a role in synthesizing Forssman glycolipid (FG), a member
of the globoseries glycolipid family. Human cells do not normally produce FG but produce the precursor
glycolipids globotriaosylceramide and globoside. This protein may be involved in the tropism and binding of
pathogenic organisms. (provided by RefSeq, Jul 2008)

GeneCards Summary for GBGT1 Gene: 
GBGT1 (globoside alpha-1,3-N-acetylgalactosaminyltransferase 1) is a protein-coding gene. Diseases associated with GBGT1 include choroiditis, and among its related super-pathways are Metabolism. GO annotations related to this gene include globoside alpha-N-acetylgalactosaminyltransferase activity and metal ion binding. An important paralog of this gene is A3GALT2.

UniProtKB/Swiss-Prot: GBGT1_HUMAN, Q8N5D6
Function: Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in
alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens

Gene Wiki entry for GBGT1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_035014.4  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GBGT1 gene promoter:
         RFX1   NCX/Ncx   Pax-2a   Roaz   Nkx6-1   Pax-2b   Cart-1   ARP-1   ATF6   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGBGT1 promoter sequence
   Search SABiosciences Chromatin IP Primers for GBGT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GBGT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.13-q34.3   Ensembl cytogenetic band:  9q34.2   HGNC cytogenetic band: 9q34.13-q34.3

GBGT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GBGT1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M136028:  view genomic region     (about GC identifiers)

Start:
136,028,340 bp from pter      End:
136,039,332 bp from pter
Size:
10,993 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GBGT1_HUMAN, Q8N5D6 (See protein sequence)
Recommended Name: Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1  
Size: 347 amino acids; 40127 Da
Cofactor: Manganese (By similarity)
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (Potential)
Caution: In contrast to its mouse or canine ortholog, it does not mediate the formation of Forssman glycolipid
(also called Forssman antigen; FG), which does not exist in human. It is unknown whether it has no enzyme
activity at all or has some distinct substrate specificity compared to the canine and mouse protein
Secondary accessions: A8K633 B2RA95 Q45F07 Q5T7U9 Q5T7V1 Q8N2K4 Q9UKI5
Alternative splicing: 2 isoforms:  Q8N5D6-1   Q8N5D6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GBGT1: NX_Q8N5D6

Explore proteomics data for GBGT1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N5D6

  • GBGT1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GBGT1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001269558.1  NP_001269561.1  NP_068836.2  

    ENSEMBL proteins: 
     ENSP00000361113   ENSP00000361110   ENSP00000361108   ENSP00000361106   ENSP00000437663  

    Human Recombinant Protein Products for GBGT1: 
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    Cloud-Clone Corp. Proteins for GBGT1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    GBGT1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GLT6: Glycosyltransferase family 6 domain containing

    1 InterPro protein domain:
     IPR005076 Glyco_trans_6

    Graphical View of Domain Structure for InterPro Entry Q8N5D6

    ProtoNet protein and cluster: Q8N5D6

    1 Blocks protein domain: IPB005076 Glycosyl transferase

    UniProtKB/Swiss-Prot: GBGT1_HUMAN, Q8N5D6
    Domain: The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the
    beta-phosphate group of UDP and may also have a role in catalysis (By similarity)
    Similarity: Belongs to the glycosyltransferase 6 family


    GBGT1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GBGT1_HUMAN, Q8N5D6
    Function: Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in
    alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens

         Enzyme Number (IUBMB): EC 2.4.1.-1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016758transferase activity, transferring hexosyl groups ----
    GO:0046872metal ion binding IEA--
    GO:0047277globoside alpha-N-acetylgalactosaminyltransferase activity IEA--
         
    GBGT1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for GBGT1:
     Synthetic lethal with Ras 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GBGT1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolic pathways0.40
    2Glycosphingolipid biosynthesis - globo series
    Glycosphingolipid biosynthesis - globo series

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2         Kegg Pathways  (Kegg details for GBGT1):
        Glycosphingolipid biosynthesis - globo series
    Metabolic pathways

    UniProtKB/Swiss-Prot: GBGT1_HUMAN, Q8N5D6
    Pathway: Protein modification; protein glycosylation


    GBGT1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GBGT1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for GBGT1 (ENSP000003611104) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    B3GALNT1ENSP000003234794STRING: ENSP00000323479
    B3GALT5ENSP000003433184STRING: ENSP00000343318
    HEXAENSP000002680974STRING: ENSP00000268097
    HEXBENSP000002614164STRING: ENSP00000261416
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process ----
    GO:0006486protein glycosylation IEA--
    GO:0009247glycolipid biosynthetic process TAS10506200

    GBGT1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GBGT1

    10/523 HMDB Compounds for GBGT1 (see all 523)    About this table
    CompoundSynonyms CAS #PubMed Ids
    3-Dehydrosphinganine1-Hydroxy-2-amino-3-oxo-octadecane (see all 9)16105-69-4--
    3-O-Sulfogalactosylceramide (d18:1/12:0)Sulfatide (d18:1/12:0) (see all 13)852100-88-0--
    3-O-Sulfogalactosylceramide (d18:1/14:0)Sulfatide (d18:1/14:0) (see all 13)----
    3-O-Sulfogalactosylceramide (d18:1/16:0)Sulfatide (d18:1/16:0) (see all 13)862509-48-6--
    3-O-Sulfogalactosylceramide (d18:1/18:0)Sulfatide (d18:1/18:0) (see all 13)244215-65-4--
    3-O-Sulfogalactosylceramide (d18:1/18:1(9Z))Sulfatide (d18:1/18:1(9Z)) (see all 13)----
    3-O-Sulfogalactosylceramide (d18:1/20:0)Sulfatide (d18:1/20:0) (see all 13)265096-81-9--
    3-O-Sulfogalactosylceramide (d18:1/22:0)Sulfatide (d18:1/22:0) (see all 13)265096-83-1--
    3-O-Sulfogalactosylceramide (d18:1/24:0)Sulfatide (d18:1/24:0) (see all 16)151122-71-3--
    3-O-Sulfogalactosylceramide (d18:1/24:1(15Z))Sulfatide (d18:1/24:1(15Z)) (see all 13)151057-28-2--

    Search CenterWatch for drugs/clinical trials and news about GBGT1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GBGT1 gene (3 alternative transcripts): 
    NM_001282629.1  NM_001282632.1  NM_021996.5  

    Unigene Cluster for GBGT1:

    Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
    Hs.495419  [show with all ESTs]
    Unigene Representative Sequence: AF163572
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372043 ENST00000470431(uc004ccy.1) ENST00000472281(uc010nac.1)
    ENST00000372040(uc010nab.3 uc011mcx.2 uc004ccw.3) ENST00000372038
    ENST00000372036 ENST00000487864 ENST00000540636
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    Additional mRNA sequence: 

    AF163572.1 AK074639.1 AK291498.1 AK303825.1 AK307687.1 AK314097.1 AY358175.1 BC032499.1 

    9 DOTS entries:

    DT.40211419  DT.100020026  DT.100020025  DT.100733001  DT.121174087  DT.97772448  DT.101982315  DT.102823390 
    DT.75136923 

    24/32 AceView cDNA sequences (see all 32):

    AA827370 CR622726 BG025899 AK074944 AA827371 BP381506 CA397865 BM923163 
    CF594044 AL576804 AI627912 BC032499 AL525920 BX389796 NM_021996 AY358175 
    AL562632 BQ574549 AI263114 BI906086 BI858477 CF993809 AK074639 BX389797 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for GBGT1 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d
    SP1:              -                 -     -     -                       -                     
    SP2:              -                 -     -     -                                             
    SP3:              -                 -     -     -                                             
    SP4:              -                 -     -     -                                             
    SP5:              -                 -     -                                                   


    ECgene alternative splicing isoforms for GBGT1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GBGT1 expression in normal human tissues (normalized intensities)      GBGT1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCCAATTC
    GBGT1 Expression
    About this image


    GBGT1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
             brain/midbrain   
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             monocyte-derived macrophage   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Gut Tube (Gastrointestinal Tract)
             Definitive endoderm-like cells ( A scalable, suspension protocol for derivation of...
     
     Spinal Cord (Nervous System)

    See GBGT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GBGT1

    SOURCE GeneReport for Unigene cluster: Hs.495419

    UniProtKB/Swiss-Prot: GBGT1_HUMAN, Q8N5D6
    Tissue specificity: Widely expressed. Expressed at higher level in placenta, ovary and peripheral blood leukocyte,
    whereas it is weakly expressed in liver, thymus, and testis

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GBGT1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for GBGT1 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gbgt11 , 5 globoside alpha-1,3-N-acetylgalactosaminyltransferase more1, 5 80.98(n)1
    79.25(a)1
      2 (19.38 cM)5
    2276711  NM_139197.21  NP_631936.21 
     284968915 
    chicken
    (Gallus gallus)
    Aves GBGT11 globoside alpha-1,3-N-acetylgalactosaminyltransferase more 66.67(n)
    64.41(a)
      417163  NM_001030683.1  NP_001025854.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC055647.12   -- 73.24(n)   387303  BC055647.1 


    ENSEMBL Gene Tree for GBGT1 (if available)
    TreeFam Gene Tree for GBGT1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GBGT1 gene
    A3GALT22  GLT6D12  
    15 SIMAP similar genes for GBGT1 using alignment to 9 protein entries:     GBGT1_HUMAN (see all proteins):
    RALGDS    IDNK    LOC100996577    SMYD4    ARIH1    PPIL6
    TNNT1    C3orf33    C4BPB    ABO-B    ABO    C11orf80
    GLT6D1    TM4SF19    ZNF554

    GBGT1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for GBGT1
    PGOHUM00000251063


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/410 SNPs in GBGT1 are shown (see all 410)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs360803511,2
    C,F,H--136027846(-) ATTCCA/CGTTCT 1 -- ds500111Minor allele frequency- C:0.11NS NA WA 1086
    rs358574661,2
    C,F--136027868(-) AGGCTA/GCAACG 1 -- ds50014Minor allele frequency- G:0.04NS NA 82
    rs1484297691,2
    --136027921(+) CGATTG/TTGTTT 1 -- ds50010--------
    rs132937451,2
    C,H--136027956(+) ACTGCC/ATGATG 1 -- ds50014Minor allele frequency- A:0.00NS EA 418
    rs358027581,2
    C,F--136027974(-) TGTCCC/TCAGTG 1 -- ds50014Minor allele frequency- T:0.10NS WA 200
    rs1893958131,2
    C--136028349(+) GCACAC/TGCCCC 1 -- ut310--------
    rs1459658071,2
    --136028393(+) AGGAGA/GTGGCT 1 -- ut310--------
    rs1927862011,2
    --136028427(+) TTTGGG/TGTGCA 1 -- ut310--------
    rs358757581,2
    C,F--136028453(-) AACAGG/ATCTAG 1 -- ut314Minor allele frequency- A:0.03NS NA 98
    rs342405121,2
    C,F--136028457(-) ATGGAA/GCAGGT 1 -- ut314Minor allele frequency- G:0.03NS NA 98

    HapMap Linkage Disequilibrium report for GBGT1 (136028340 - 136039332 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/16 variations for GBGT1 (see all 16):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2739138CNV Deletion23290073
    nsv894036CNV Loss21882294
    dgv8320n71CNV Loss21882294
    nsv894034CNV Loss21882294
    dgv8324n71CNV Loss21882294
    nsv894049CNV Loss21882294
    nsv894030CNV Loss21882294
    nsv508565CNV Loss20534489
    dgv8323n71CNV Gain21882294
    dgv8322n71CNV Gain21882294


    Human Gene Mutation Database (HGMD): GBGT1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing GBGT1
    DNA2.0 Custom Variant and Variant Library Synthesis for GBGT1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606074    OMIM disorders: --

    2 diseases for GBGT1:    About MalaCards
    choroiditis    


    GBGT1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): GBGT1
    Human Genome Epidemiology (HuGE) Navigator: GBGT1 (1 document)

    Export disorders for GBGT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GBGT1 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with GBGT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human Forssman synthetase gene: an evolving association between glycolipid synthesis and host-microbial interactions. (PubMed id 10506200)1, 2, 3, 9 Xu H.... Haslam D.B. (1999)
    2. Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)1, 4 Flachsbart F....Nebel A. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. Expression cloning of Forssman glycolipid synthetase: a novel member of the histo-blood group ABO gene family. (PubMed id 8855242)1, 3 Haslam D.B. and Baenziger J.U. (1996)
    8. Forssman expression on human erythrocytes: biochemical and genetic evidence of a new histo-blood group system. (PubMed id 23255552)1 Svensson L....Olsson M.L. (2013)
    9. Genome-wide association identifies the ABO blood grou p as a major locus associated with serum levels of soluble E-selectin. (PubMed id 19729612)4 Paterson A.D....Bull S.B. (2009)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26301 HGNC: 20460 AceView: GBGT1 Ensembl:ENSG00000148288 euGenes: HUgn26301
    ECgene: GBGT1 Kegg: 26301 H-InvDB: GBGT1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GBGT1 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/
    SeattleSNPshttp://pga.gs.washington.edu/data/gbgt1/
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_479

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GBGT1 gene:
    Search GeneIP for patents involving GBGT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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