Aliases for GBGT1 Gene
External Ids for GBGT1 Gene
Previous GeneCards Identifiers for GBGT1 Gene
This gene encodes a glycosyltransferase that plays a role in the synthesis of Forssman glycolipid (FG), a member of the globoseries glycolipid family. Glycolipids such as FG form attachment sites for the binding of pathogens to cells; expression of this protein may determine host tropism to microorganisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for GBGT1 Gene
GBGT1 (Globoside Alpha-1,3-N-Acetylgalactosaminyltransferase 1 (FORS Blood Group)) is a Protein Coding gene. Among its related pathways are Globo Sphingolipid Metabolism and Metabolism. GO annotations related to this gene include transferase activity, transferring hexosyl groups and globoside alpha-N-acetylgalactosaminyltransferase activity. An important paralog of this gene is ABO.
UniProtKB/Swiss-Prot for GBGT1 Gene
Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens.