GBF1 Gene
protein-coding GIFtS: 61
GCID: GC10P103995
|
|
golgi brefeldin A resistant guanine nucleotide exchange...(Previous name: golgi-specific brefeldin A resistance factor 1 )
| |
Aliases for GBF1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Golgi Brefeldin A Resistant Guanine Nucleotide Exchange Factor 11 2 | | ARF1GEF1 2 | | KIAA02481 3 | | BFA-Resistant GEF 12 3 | | Golgi-Specific Brefeldin A Resistance Factor 11 | | Golgi-Specific Brefeldin A-Resistance Guanine Nucleotide Exchange Factor 12 |
Export aliases for GBF1 gene to outside databasesPrevious GC identifers: GC10P102898 GC10P103238 GC10P104136 GC10P103669 GC10P097637 |
Summaries for GBF1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for GBF1: This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor thatregulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localizedto the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encodedprotein has also been identified as an important host factor for viral replication. Multiple transcript variants havebeen observed for this gene. (provided by RefSeq, Dec 2010) UniProtKB/Swiss-Prot: GBF1_HUMAN, Q92538Function: Promotes guanine-nucleotide exchange on ARF5. Promotes the activation of ARF5 through replacement of GDP withGTP (By similarity) Gene Wiki entry for GBF1
|
Genomic Views for GBF1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GBF1 gene promoter: CREB PPAR-alpha C/EBPbeta POU3F1 HOXA5 deltaCREB c-Myb NF-AT Other transcription factors
Search SABiosciences Chromatin IP Primers for GBF1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GBF1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q24 Ensembl cytogenetic band: 10q24.32 HGNC cytogenetic band: 10q24GBF1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P103995: view genomic region
(about GC identifiers)
Start:
|
104,005,289 bp from pter |
End:
|
104,142,656 bp from pter |
Size:
|
137,368 bases |
Orientation:
|
plus strand |
|
Proteins for GBF1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: GBF1_HUMAN, Q92538 (See
protein sequence)Recommended Name: Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Size: 1859 amino acids; 206446 Da
Sequence caution: Sequence=BAA13379.2; Type=Erroneous initiation;
Secondary accessions: Q5VXX3 Q96CK6 Q96HZ3 Q9H473Explore the universe of human proteins at neXtProt for GBF1: NX_Q92538
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q92538 GBF1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001186307.1 NP_001186308.1 NP_004184.1 ENSEMBL proteins: ENSP00000359000 Reactome Protein details: Q92538 Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
GBF1 for ontologies About GeneDecksing
GBF1 Antibody Products: Assay Products for GBF1: |
Protein
Domains / Families for GBF1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GBF1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q92538ProtoNet protein and cluster: Q92538 1 Blocks protein family: IPB000904 SEC7-like domain
UniProtKB/Swiss-Prot: GBF1_HUMAN, Q92538Similarity: Contains 1 SEC7 domain |
Function for GBF1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: GBF1_HUMAN, Q92538Function: Promotes guanine-nucleotide exchange on ARF5. Promotes the activation of ARF5 through replacement of GDP withGTP (By similarity)Enzyme regulation: Inhibited by brefeldin A (By similarity) Genatlas biochemistry entry for GBF1:Golgi specific brefeldin A resistance factor,housekeeping gene,predominantly expressed in testis and pancreas,Sec7domain family
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GBF1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GBF1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): GBF1 (NM_004193) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GBF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GBF1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GBF1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity |
IBA | -- | | GO:0005515 | protein binding |
-- | -- |
GBF1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for GBF1: Animal Models: 1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Gbf1):
GBF1 for phenotypes About GeneDecksing
|
Pathways & Interactions for GBF1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Clathrin derived vesicle budding | | | 2 | Coatomer:Arf1-GTP:GAP lattice formation on golgi membrane | | | 3 | Membrane Trafficking | | | 4 | Arf1 pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
1 BioSystems Pathway for GBF1 
5
Reactome Pathways for GBF1
GBF1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GBF1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
 5/47 Interacting proteins for GBF1 (Q925382, 3 ENSP000003590004) via UniProtKB, MINT, STRING, and/or I2D (see all 47)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER |
TAS | -- | | GO:0006892 | post-Golgi vesicle-mediated transport |
TAS | -- | | GO:0016044 | cellular membrane organization |
TAS | -- | | GO:0016192 | vesicle-mediated transport |
IBA | -- | | GO:0032012 | regulation of ARF protein signal transduction |
IEA | -- |
GBF1 for ontologies About GeneDecksing
|
Drugs & Compounds for GBF1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
GBF1 for compounds About GeneDecksing
Browse Tocris compounds for GBF1
1 HMDB Compound for GBF1 About this table 3 Novoseek chemical compound relationships for GBF1 gene About this table
Search CenterWatch for drugs/clinical trials and news about GBF1 
|
Transcripts for GBF1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for GBF1 gene (3 alternative transcripts): NM_001199378.1 NM_001199379.1 NM_004193.2 Unigene Cluster for GBF1: Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Hs.290243 [show with all ESTs]Unigene Representative Sequence: NM_0041932 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369983(uc001kuw.3 uc001kuy.2 uc001kuz.2 uc001kux.2) ENST00000476019
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GBF1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GBF1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): GBF1 (NM_004193) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GBF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GBF1  |
Additional cDNA sequence: AF068755.1 AK024916.1 AK025153.1 AK025330.1 BC007941.2 BC014171.2 BC032543.1 BC057804.1 BC068543.1 BC117681.1 BC117682.1 D87435.2 21 DOTS entries: DT.95141321 DT.217401 DT.121279880 DT.100804666 DT.100737629 DT.75174816 DT.91750516 DT.100030316 DT.121279858 DT.121279873 DT.121279878 DT.121279953 DT.40275862 DT.92412719 DT.92466573 DT.95324072 DT.95340055 DT.95340230 DT.121279870 DT.219676 DT.99968159 24/416 AceView cDNA sequences (see all 416): AI458484 AA987967 AW328049 BQ432489 BF725034 BF431337 CD618167 BM561519 AI916098 BQ919138 CD618169 AI161349 BM470123 CD673498 AI458563 BE250212 AA432114 AI378499 BQ684713 BU944699 CF243130 AW328048 CA866821 CD674720 GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for GBF1 (see all 14) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21 | ^ | |
| SP1: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28a | · | 28b | · | 28c | ^ | 29 | ^ | 30a | · | 30b | · | 30c | ^ | 31 | ^ | 32a | · | 32b | · | 32c | ^ | 33a | · | 33b | · | 33c | ^ | 34a | · | 34b | ^ | 35a | · | 35b | ^ | 36a | · | 36b | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | - |   | |   | - |   | - |   | |   | - |   | |   | |   | |   | - |   | - |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | - |   | |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   |
| ExUns: | 37 | ^ | 38a | · | 38b | ^ | 39a | · | 39b | ^ | 40 | ^ | 41 | ^ | 42a | · | 42b | |
| SP1: | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for GBF1
|
Expression for GBF1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GBF1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TACATATGGA
About this image See GBF1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GBF1
SOURCE GeneReport for Unigene cluster: Hs.290243 UniProtKB/Swiss-Prot: GBF1_HUMAN, Q92538Tissue specificity: Ubiquitous SABiosciences Custom PCR Arrays for GBF1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GBF1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GBF1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GBF1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GBF1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GBF1 |
Orthologs for GBF1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for GBF1 gene from 8/27 species (see all 27) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
GBF11 |
golgi brefeldin A resistant guanine nucleotide exchange more |
76.24(n) 84.99(a) |
  |
423758 XM_421632.3 XP_421632.3 |
lizard (Anolis carolinensis) |
Reptilia |
GBF16 |
-- |
87(a) |
1 ↔ 1 |
GL343196.1(538347-562216) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.167612 |
Xenopus laevis transcribed sequence with moderate similarity more |
77.67(n) |
  |
BJ066700.1 |
zebrafish (Danio rerio) |
Actinopterygii |
si:dkey-183c23.11 |
si:dkey-183c23.1 |
70.97(n) 77.5(a) |
  |
566350 XM_689622.5 XP_694714.5 |
fruit fly (Drosophila melanogaster) |
Insecta |
garz1 , 3 |
ER to Golgi transport ARF small monomeric GTPase3 gartenzwerg1 |
44(a)3 52.97(n)1 47.4(a)1 |
  |
363371 NM_136917.31 NP_610761.21 |
worm (Caenorhabditis elegans) |
Secernentea |
gbf-11 |
Protein GBF-1 |
49.81(n) 43.64(a) |
  |
176609 NM_067121.2 NP_499522.2 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
GN1 |
Pattern formation protein EMB30 |
48.39(n) 39.75(a) |
  |
837958 NM_101264.3 NP_172851.1 |
rice (Oryza sativa) |
Liliopsida |
Os03g06661001 |
hypothetical protein |
47.67(n) 38.1(a) |
  |
4333660 NM_001057379.1 NP_001050844.1 |
ENSEMBL Gene Tree for GBF1 (if available) TreeFam Gene Tree for GBF1 (if available)  |
Paralogs for GBF1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for GBF1 gene
- PSD32 CYTH32 IQSEC32 CYTH22 ARFGEF22 PSD42 ARFGEF12 IQSEC12
- PSD22 PSD2 IQSEC22 CYTH42 CYTH12 FBXO82
2 SIMAP similar genes for GBF1 using alignment to 5 protein entries: GBF1_HUMAN (see all proteins):CYTH1 FLJ00017
GBF1 for paralogs About GeneDecksing
|
Genomic Variants for GBF1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 10 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for GBF1 (104005289 - 104142656 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for GBF1 1 Indel: 71103  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GBF1 |
|
Disorders
/ Diseases for GBF1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GBF1 for disorders About GeneDecksing
OMIM gene information: 603698
OMIM disorders: --
6 diseases for GBF1: About MalaCardsretinitis pigmentosa hepatitis c alzheimer's disease retinitis breast cancer hepatitis Human Genome Epidemiology (HuGE) Navigator: GBF1 (15 documents) Export disorders for GBF1 gene to outside databases
|
Publications for GBF1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GBF1 gene, integrated from 9 sources (see all 79): (articles sorted by number of sources associating them with GBF1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Human GBF1 is a ubiquitously expressed gene of the sec7 domain family mapping to 10q24. (PubMed id 9828135)1, 2, 3 Mansour S.J.... Melancon P. (1998)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2 Nagase T....Nomura N. (1996)
- Dissection of membrane dynamics of the ARF-guanine nucleotide exchange factor GBF1. (PubMed id 15813748)1, 9 Szul T....Sztul E. (2005)
- AMP-activated protein kinase phosphorylates Golgi-specific brefeldin A resistance factor 1 at Thr1337 to induce disassembly of Golgi apparatus. (PubMed id 18063581)1, 9 Miyamoto T....Yonezawa K. (2008)
- Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi. (PubMed id 15616190)1, 9 Niu T.K....Jackson C.L. (2005)
- Molecular determinants of the interaction between coxsackievirus protein 3A and guanine nucleotide exchange factor GBF1. (PubMed id 17329336)1, 9 Wessels E....van Kuppeveld F.J. (2007)
- GBF1: A novel Golgi-associated BFA-resistant guanine nucleotide exchange factor that displays specificity for ADP-ribosylation factor 5. (PubMed id 10402461)1, 9 Claude A....Melancon P. (1999)
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External Searches for GBF1 gene
(in PubMed,
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Genome Databases showing GBF1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
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Kegg,
and/or
H-InvDB)
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Other Databases showing GBF1 gene
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Specialized Databases showing GBF1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
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| Name | Description |
| PharmGKB entry for GBF1 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for GBF1 gene: Search GeneIP for patents involving GBF1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for GBF1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for GBF1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GBF1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GBF1 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for GBF1 | | OriGene 3'-UTR Clone for GBF1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GBF1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GBF1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for GBF1 | | OriGene Custom Protein Services for GBF1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GBF1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GBF1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GBF1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GBF1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GBF1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GBF1 |
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| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GBF1 |
|  |  |  | | | Search ThermoFisher Antibodies for GBF1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GBF1 |
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