Aliases for GATSL3 Gene
External Ids for GATSL3 Gene
Previous GeneCards Identifiers for GATSL3 Gene
GeneCards Summary for GATSL3 Gene
GATSL3 (GATS Protein Like 3) is a Protein Coding gene. An important paralog of this gene is GATSL2.
UniProtKB/Swiss-Prot for GATSL3 Gene
Functions as an intracellular arginine sensor that regulates the TORC1 signaling pathway through the GATOR complex. As a homooligomer or a heterooligomer with GATSL2, directly binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of arginine to GATSL3 disrupts the interaction of GATSL3-containing oligomers with GATOR2 and activates the TORC1 signaling pathway.