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Aliases for GATSL2 Gene

Aliases for GATSL2 Gene

  • GATS Protein-Like 2 2 3 5
  • GATS Protein-Like 1 2 3
  • GATSL1 3 4
  • GATS-Like Protein 1 3

External Ids for GATSL2 Gene

Previous HGNC Symbols for GATSL2 Gene

  • GATSL1

Previous GeneCards Identifiers for GATSL2 Gene

  • GC07M074647
  • GC07M074807

Summaries for GATSL2 Gene

GeneCards Summary for GATSL2 Gene

GATSL2 (GATS Protein-Like 2) is a Protein Coding gene. An important paralog of this gene is GATSL3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GATSL2 Gene

Genomics for GATSL2 Gene

Regulatory Elements for GATSL2 Gene

Enhancers for GATSL2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GATSL2 on UCSC Golden Path with GeneCards custom track

Promoters for GATSL2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GATSL2 on UCSC Golden Path with GeneCards custom track

Genomic Location for GATSL2 Gene

Chromosome:
7
Start:
74,964,818 bp from pter
End:
75,031,532 bp from pter
Size:
66,715 bases
Orientation:
Plus strand

Genomic View for GATSL2 Gene

Genes around GATSL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GATSL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GATSL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GATSL2 Gene

Proteins for GATSL2 Gene

  • Protein details for GATSL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NHX0-GATL2_HUMAN
    Recommended name:
    GATS-like protein 2
    Protein Accession:
    A6NHX0
    Secondary Accessions:
    • A6NNH0
    • B9EJH9

    Protein attributes for GATSL2 Gene

    Size:
    329 amino acids
    Molecular mass:
    36056 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GATSL2 Gene

Proteomics data for GATSL2 Gene at MOPED

Post-translational modifications for GATSL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GATSL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GATSL2 Gene

Domains & Families for GATSL2 Gene

Protein Domains for GATSL2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GATSL2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NHX0

UniProtKB/Swiss-Prot:

GATL2_HUMAN :
  • Belongs to the GATS family.
Family:
  • Belongs to the GATS family.
genes like me logo Genes that share domains with GATSL2: view

No data available for Gene Families for GATSL2 Gene

Function for GATSL2 Gene

Phenotypes for GATSL2 Gene

GenomeRNAi human phenotypes for GATSL2:
genes like me logo Genes that share phenotypes with GATSL2: view

Animal Model Products

CRISPR Products

miRNA for GATSL2 Gene

miRTarBase miRNAs that target GATSL2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GATSL2 Gene

Localization for GATSL2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GATSL2 Gene

Pathways & Interactions for GATSL2 Gene

SuperPathways for GATSL2 Gene

No Data Available

Interacting Proteins for GATSL2 Gene

Gene Ontology (GO) - Biological Process for GATSL2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GATSL2 Gene

Drugs & Compounds for GATSL2 Gene

No Compound Related Data Available

Transcripts for GATSL2 Gene

mRNA/cDNA for GATSL2 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GATSL2 Gene

GATS protein-like 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GATSL2 Gene

No ASD Table

Relevant External Links for GATSL2 Gene

GeneLoc Exon Structure for
GATSL2
ECgene alternative splicing isoforms for
GATSL2

Expression for GATSL2 Gene

mRNA expression in normal human tissues for GATSL2 Gene

mRNA expression in normal human tissues for GATSL2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GATSL2 Gene

This gene is overexpressed in Muscle - Skeletal (x10.7).

Protein differential expression in normal tissues from HIPED for GATSL2 Gene

This gene is overexpressed in Ovary (16.4), Tonsil (15.0), Retina (14.4), Uterus (8.8), and Fetal Brain (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for GATSL2 Gene



SOURCE GeneReport for Unigene cluster for GATSL2 Gene Hs.647048

genes like me logo Genes that share expression patterns with GATSL2: view

Protein tissue co-expression partners for GATSL2 Gene

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for GATSL2 Gene

Orthologs for GATSL2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GATSL2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia GATSL2 35
  • 91.69 (n)
  • 98.48 (a)
dog
(Canis familiaris)
Mammalia GATSL2 35
  • 88.78 (n)
  • 96.97 (a)
mouse
(Mus musculus)
Mammalia Gatsl2 35
  • 88.86 (n)
  • 97.26 (a)
Gatsl2 16
chimpanzee
(Pan troglodytes)
Mammalia GATSL2 35
  • 99.9 (n)
  • 100 (a)
rat
(Rattus norvegicus)
Mammalia Gatsl2 35
  • 87.84 (n)
  • 97.57 (a)
chicken
(Gallus gallus)
Aves GATSL2 35
  • 81.07 (n)
  • 91.54 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia gatsl1 35
  • 79.23 (n)
  • 92.4 (a)
zebrafish
(Danio rerio)
Actinopterygii gatsl2 35
  • 75.36 (n)
  • 84.05 (a)
Species with no ortholog for GATSL2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GATSL2 Gene

ENSEMBL:
Gene Tree for GATSL2 (if available)
TreeFam:
Gene Tree for GATSL2 (if available)

Paralogs for GATSL2 Gene

Paralogs for GATSL2 Gene

(4) SIMAP similar genes for GATSL2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with GATSL2: view

Variants for GATSL2 Gene

Sequence variations from dbSNP and Humsavar for GATSL2 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1635758 -- 74,963,874(-) GCGCC(C/G)GGACC upstream-variant-2KB
rs13222600 -- 75,021,337(-) ccagc(C/T)tggtc intron-variant
rs13222683 -- 75,021,311(-) catct(C/T)tacga intron-variant
rs13237684 -- 75,021,343(-) tggag(A/C)ccagc intron-variant
rs13246912 -- 75,021,360(-) cacat(C/G)cagtc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GATSL2 Gene

Variant ID Type Subtype PubMed ID
dgv2100e1 CNV Complex 17122850
nsv888381 CNV Gain 21882294
nsv528969 CNV Gain 19592680
dgv2101e1 CNV Complex 17122850
dgv2102e1 CNV Complex 17122850
essv14753 CNV CNV 17122850

Variation tolerance for GATSL2 Gene

Gene Damage Index Score: 0.20; 4.51% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for GATSL2 Gene

Disorders for GATSL2 Gene

Relevant External Links for GATSL2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GATSL2

No disorders were found for GATSL2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GATSL2 Gene

Publications for GATSL2 Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Toward a complete human genome sequence. (PMID: 9847074) Sulston J.E. … Waterston R. (Genome Res. 1998) 3

Products for GATSL2 Gene

Sources for GATSL2 Gene

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