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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GATA5 Gene

protein-coding   GIFtS: 57
GCID: GC20M061038

GATA binding protein 5

(Previous name: GATA-binding protein 5 )
 Explore 13 diseases affiliated with
GATA5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for GATA5    

Aliases
for GATA5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
GATA Binding Protein 51 2
BB379O24.11
GATA-Binding Protein 51 2
GATA-Binding Factor 52 3
GATA Binding Factor-52
Transcription Factor GATA-52

External Ids:    HGNC: 158021   Entrez Gene: 1406282   Ensembl: ENSG000001307007   OMIM: 6114965   UniProtKB: Q9BWX53   

Export aliases for GATA5 gene to outside databases

Previous GC identifers: GC20M060803 GC20M061676 GC20M061723 GC20M060471 GC20M057816


Summaries
for GATA5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for GATA5:
The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded
protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for
cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins
may be involved in the establishment of cardiac smooth muscle cell diversity. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: GATA5_HUMAN, Q9BWX5
Function: Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac
troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies
smooth muscle cell diversity (By similarity)

Gene Wiki entry for GATA5


Genomic Views
for GATA5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GATA5 gene promoter:
         AP-2alpha isoform 3   AP-2alpha isoform 2   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for GATA5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GATA5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

GATA5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GATA5 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M061038:  view genomic region     (about GC identifiers)

Start:
 61,038,553 bp from pter      End:
 61,051,026 bp from pter
Size:
 12,474 bases      Orientation:
 minus strand

Proteins
for GATA5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: GATA5_HUMAN, Q9BWX5 (See protein sequence)
Recommended Name: Transcription factor GATA-5  
Size: 397 amino acids; 41299 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q17RE2

Explore the universe of human proteins at neXtProt for GATA5: NX_Q9BWX5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BWX5

    • GATA5 Protein expression data from MOPED and PaxDb:    About this image 
    GATA5 Protein Expression
    REFSEQ proteins: NP_536721.1  
    ENSEMBL proteins: 
     ENSP00000252997  
    Reactome Protein details: Q9BWX5
    Human Recombinant Protein Products for GATA5: 
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    OriGene Protein Over-expression Lysate: GATA5
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    Novus Biologicals GATA5 Proteins
    Novus Biologicals GATA5 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for GATA5

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA9566909
    GO:0005654nucleoplasm TAS--

    GATA5 for ontologies           About GeneDecksing



    GATA5 Antibody Products: 
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    Uscn ELISAs and CLIAs for GATA5

    Protein Domains /
    Families
    for GATA5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    GATA5 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR000679 Znf_GATA
     IPR016375 TF_GATA_4/5/6
     IPR013088 Znf_NHR/GATA
     IPR008013 GATA_N

    Graphical View of Domain Structure for InterPro Entry Q9BWX5

    ProtoNet protein and cluster: Q9BWX5

    3 Blocks protein families:
    IPB000679 Zn-finger
    IPB001917 Aminotransferase
    IPB008013 GATA-type transcription activator


    UniProtKB/Swiss-Prot: GATA5_HUMAN, Q9BWX5
    Similarity: Contains 2 GATA-type zinc fingers


    Function
    for GATA5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GATA5_HUMAN, Q9BWX5
    Function: Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac
    troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies
    smooth muscle cell diversity (By similarity)

         Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001158enhancer sequence-specific DNA binding IEA--
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IDA14986113
    GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding ----
         
    GATA5 for ontologies           About GeneDecksing


    Phenotypes:
         11 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Gata5):
     cardiovascular system  cellular  digestive/alimentary  endocrine/exocrine gland  homeostasis/metabolism 
     immune system  mortality/aging  muscle  renal/urinary system  reproductive system 
     skeleton 

    GATA5 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-outs for GATA5: Gata5tm1Eno Gata5tm1.2Nemr
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for GATA5 

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: GATA5 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GATA5 (see all 7)
    OriGene shRNA RFP: GATA5
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for GATA5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Factors involved in megakaryocyte development and platelet production
    		Factors involved in megakaryocyte development and platelet production1.00
    2DREAM Repression and Dynorphin Expression
    		BMP Pathway0.44
    3Platelet activation, signaling and aggregation
    		Hemostasis0.43
    4G-AlphaQ Signaling
    		Thrombin Signaling0.40

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GATA5
        BMP Pathway
    Thrombin Signaling

    2        Reactome Pathways for GATA5
        Hemostasis
    Factors involved in megakaryocyte development and platelet production



    GATA5 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GATA5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/102 Interacting proteins for GATA5 (Q9BWX53 ENSP000002529974) via UniProtKB, MINT, STRING, and/or I2D (see all 102)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EP300Q094723, ENSP000002632534I2D: score=1 STRING: ENSP00000263253
    HNF1AP208233, ENSP000002575554I2D: score=1 STRING: ENSP00000257555
    KLF2Q9Y5W33, ENSP000002480714I2D: score=1 STRING: ENSP00000248071
    SMAD4Q134853, ENSP000003415514I2D: score=1 STRING: ENSP00000341551
    RORBQ927533I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0007596blood coagulation TAS--
    GO:0045893positive regulation of transcription, DNA-dependent ----
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IDA14986113
    GO:0060575intestinal epithelial cell differentiation IDA9566909

    GATA5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for GATA5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    GATA5 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GATA5
    2 Novoseek chemical compound relationships for GATA5 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    5-aza-2'deoxycytidine 62.9 4 17912029 (1), 16823849 (1)
    zinc 33.1 1 9915795 (1)

    Search CenterWatch for drugs/clinical trials and news about GATA5 

    Transcripts
    for GATA5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for GATA5 gene: 
    NM_080473.4  

    Unigene Cluster for GATA5:

    GATA binding protein 5
    Hs.352250  [show with all ESTs]
    Unigene Representative Sequence: BC047790
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000252997(uc002ycx.1)

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    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GATA5 (see all 7)
    OriGene shRNA RFP: GATA5
    OriGene siRNA: GATA5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GATA5
    Sirion Biotech Custom design and validation of potent shRNA sequences against GATA5 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GATA5
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GATA5 
    Primer
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    Additional cDNA sequence: 

    BC047790.1 BC117356.1 BC117358.1 

    4 DOTS entries:

    DT.95152644  DT.97802394  DT.210529  DT.80102085 

    24/30 AceView cDNA sequences (see all 30):

    BQ953830 BX113152 BM985050 AA972923 AL844340 BM974967 AA127913 AW770386 
    BI767359 CA443143 AL844350 NM_080473 BX099962 BU683127 BC047790 AW070312 
    BM972115 AI685293 AW511251 AA127875 AI174441 N72525 H80289 H80275 

    GeneLoc Exon Structure


    Expression
    for GATA5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GATA5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACCATTTCTG
    GATA5 Expression
    About this image

    GATA5 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    8 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    HeartEndocardiumEndocardial CellsEndocardium
    Gut TubeForegutForegut Endoderm CellsEndoderm
    Gut TubeVentral Foregut EndodermVentral Foregut Endoderm CellsEndoderm
    LungLung MesodermEarly Lung Mesoderm CellsLung
    LungTracheaAirway Smooth Muscle CellsLung, Smooth Muscle
    HeartEndocardiumCushion Mesenchymal CellsEndocardium
    HeartEndocardiumEndocardial Tube CellsEndocardium
    LimbLimb BudLimb
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    Primitive gut tube-like cells (A scalable, suspensi...)
    Podocalyxin+, CD24+, GCTM2- (Derivation and sorti...)

    See GATA5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GATA5

    SOURCE GeneReport for Unigene cluster: Hs.352250
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GATA5

    Orthologs
    for GATA5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for GATA5 gene from 5/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves GATA51 GATA binding protein 5 69.88(n)
    66.58(a)    		   396391  NM_205421.1  NP_990752.1 
    lizard
    (Anolis carolinensis)    		 Reptilia GATA56
    		 --
    		 61(a)
    		 1 ↔ 1
    		 4(151490948-151528775)
    African clawed frog
    (Xenopus laevis)    		 Amphibia GATA-5a2 transcription factor xGATA-5a 74.06(n)    L13701.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii gata51 GATA-binding protein 5 62.76(n)
    61.04(a)    		   30482  NM_131235.2  NP_571310.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta pnr3 blastoderm segmentation transcription factor 80(a)
    (best of 2)    		     --


    ENSEMBL Gene Tree for GATA5 (if available)
    TreeFam Gene Tree for GATA5 (if available) 

    Paralogs
    for GATA5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GATA5 gene
    GATA62  GATA32  GATA42  GATA22  GATA12  
    4 SIMAP similar genes for GATA5 using alignment to 3 protein entries:     GATA5_HUMAN (see all proteins):
    GATA4    GATA6    GATA2    GATA3

    GATA5 for paralogs           About GeneDecksing



    Genomic Variants
    for GATA5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/357 NCBI SNPs in GATA5 are shown (see all 357)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs733032921,2
    		C--57829983(+) TTCAGG/ACCTGT 1 -- int13Minor allele frequency- A:0.02CSA NS WA 673
    rs759544621,2
    		C,F--61038162(+) CAGGCC/TTGTTG 1 -- ds50012Minor allele frequency- T:0.02NS WA 658
    rs1902252261,2
    		--61038179(+) ACTGCC/TGAGCC 1 -- ds50010--------
    rs60612411,2
    		C,H--61038214(+) CTCTCC/TCAGCC 1 -- ds500112Minor allele frequency- T:0.11NA WA CSA NS EA 928
    rs1139715611,2
    		F--61038224(-) GGTCCC/TCAGCG 1 -- ds50011Minor allele frequency- T:0.00NS 558
    rs61216091,2
    		C,F,A,H--61038322(+) CAGAAT/CGCAGA 1 -- ds500126Minor allele frequency- C:0.31NS EA NA WA 3034
    rs1824842301,2
    		--61038335(+) ATAGCC/TGGAAA 1 -- ds50010--------
    rs1118636261,2
    		F--61038342(-) CTAGCG/AATTTC 1 -- ds50011Minor allele frequency- A:0.00NS 560
    rs1131453151,2
    		F--61038423(-) CACCCG/ATGGGG 1 -- ds50011Minor allele frequency- A:0.03NS 560
    rs1119163781,2
    		C--61038471(-) TCTCCC/TCCTAC 1 -- ds50013Minor allele frequency- T:0.03CSA NS WA 660

    HapMap Linkage Disequilibrium report for GATA5 (61038553 - 61051026 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for GATA5
         4 CNVs: 4106 5347 30131 30130
    Human Gene Mutation Database (HGMD): GATA5

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    Disorders / Diseases
    for GATA5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    GATA5 for disorders           About GeneDecksing

    OMIM gene information: 611496    OMIM disorders: --

    UniProtKB/Swiss-Prot: GATA5_HUMAN, Q9BWX5
  • Note=Rare variants in GATA5 may be a cause of susceptibility to atrial fibrillation, a common sustained
    • cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and
    ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in
    palpitations, syncope, thromboembolic stroke, and congestive heart failure

    13 diseases for GATA5:    About MalaCards
    familial atrial fibrillation    atrial fibrillation    esophageal cancer    esophagitis
    gastric cancer    pancreatic cancer    colorectal cancer    lung cancer
    breast cancer    pancreatitis    thyroiditis    neuronitis
    carcinoma

    1 disease from the University of Copenhagen DISEASES database for GATA5:
    Familial atrial fibrillation

    2 Novoseek disease relationships for GATA5 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenocarcinoma 20.7 3 17167178 (1), 16823849 (1)
    tumors 0 6 17912029 (3), 16823849 (1)


    Export disorders for GATA5 gene to outside databases

    Publications
    for GATA5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GATA5 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with GATA5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation. (PubMed id 9566909)1, 3, 9 Gao X....Evans T. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    4. Methylation of GATA-4 and GATA-5 and development of s poradic gastric carcinomas. (PubMed id 20222162)1, 9 Wen X.Z....Deng D.J. (2010)
    5. Evaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor types. (PubMed id 17912029)1, 9 Fu B....Iacobuzio-Donahue C.A. (2007)
    6. p300 protein as a coactivator of GATA-5 in the transcription of cardiac-restricted atrial natriuretic factor gene. (PubMed id 10567378)1, 9 Kakita T....Sasayama S. (1999)
    7. Hypermethylation of the GATA gene family in esophageal cancer. (PubMed id 16823849)1, 9 Guo M....Herman J.G. (2006)
    8. Hypermethylation of the GATA genes in lung cancer. (PubMed id 15585625)1, 9 Guo M....Brock M.V. (2004)
    9. Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter. (PubMed id 12011060)1, 9 van Wering H.M....Krasinski S.D. (2002)
    10. Transcription factor GATA-5 selectively up-regulates mucin gene expression. (PubMed id 14986113)1, 9 Ren C.Y....Yuasa Y. (2004)

    External Searches for GATA5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing GATA5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 140628 HGNC: 15802 AceView: GATA5 Ensembl:ENSG00000130700 euGenes: HUgn140628
    ECgene: GATA5 H-InvDB: GATA5

    Other Databases showing GATA5 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing GATA5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GATA5 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for GATA5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for GATA5 gene:
    Search GeneIP for patents involving GATA5

    GeneCards and IP:
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