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GATA2 Gene

protein-coding GIFtS: 63

GC03M129680

GATA binding protein 2
(Previous name: GATA-binding protein 2 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
FLJ45948 ^²
MGC2306 ^²
NFE1B ^¹, ²

Descriptions
GATA binding protein 2 ^²
GATA-binding protein 2 ^¹, ², ³
endothelial transcription factor GATA-2 ^²

External Ids
HGNC: 4171¹
Entrez Gene: 2624²
UniProtKB: P23769³
Ensembl: ENSG00000179348⁷

Search outside databases for aliases for GATA2 gene

Previous GC identifers: GC03U990039 GC03M129481 GC03M129519

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for GATA2:

This gene encodes a member of the GATA family of zinc-finger transcription factors that are named

for the consensus nucleotide sequence they bind in the promoter regions of target genes. The

encoded protein plays an essential role in regulating transcription of genes involved in the

development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing

results in multiple transcript variants.

UniProtKB/Swiss-Prot: GATA2_HUMAN, P23769

Function: Transcriptional activator which regulates endothelin-1 gene expression in endothelial

cells. Binds to the consensus sequence 5'-AGATAG-3'

Gene Wiki entry for GATA2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the GATA2 gene

Entrez Gene cytogenetic band: 3q21.3 Ensembl cytogenetic band: 3q21.3 HGNC cytogenetic band: 3q21

GATA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M129680: (about GC identifiers)

Start:	129,680,960 bp from pter
End:	129,694,718 bp from pter
Size:	13,759 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000003.10 NT_005612.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: GATA2_HUMAN, P23769 (See protein sequence)

Recommended Name: Endothelial transcription factor GATA-2

Size: 480 amino acids; 50500 Da

Subcellular location: Nucleus

Sequence caution: Sequence=AAA35869.1; Type=Miscellaneous discrepancy; Note=Several sequencing

errors;

Secondary accessions: Q96BH0 Q9BUJ6

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_001139133.1 NP_001139134.1 NP_116027.2

ENSEMBL proteins:

ENSP00000345681

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (GATA2)
	Human Recombinant Proteins from Abnova (GATA2)

OriGene Purified Recombinant Human Protein: GATA2

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005730	NOT nucleolus	IDA	18029348

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Antibodies for GATA2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for GATA2
	R&D Systems Antibodies for GATA2 (GATA-2)
	Cell Signaling Technology (CST) Antibodies for GATA2 (GATA-2)
	Antibodies from Abcam (GATA2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (GATA2)
	Novus Biologicals Antibodies for GATA2

Assays for GATA2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P23769

ProtoNet protein and cluster: P23769

1 Blocks protein family: IPB000679 Zn-finger

UniProtKB/Swiss-Prot: GATA2_HUMAN, P23769

Similarity: Contains 2 GATA-type zinc fingers

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GATA2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GATA2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): BC015613

Applied Biosystems Silencer® siRNAs for GATA2

Sigma-Aldrich siRNA for GATA2

Sigma-Aldrich shRNA for GATA2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for GATA2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001145661
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001145661
untagged cDNA clones in CMV expression vector (see all 5): BC015613

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_032638

UniProtKB/Swiss-Prot: GATA2_HUMAN, P23769

Function: Transcriptional activator which regulates endothelin-1 gene expression in endothelial

cells. Binds to the consensus sequence 5'-AGATAG-3'

Genatlas biochemistry entry for GATA2:

endothelial cell transcription factor,GATA sequence binding protein,expressed in immature RBC,mast

cell,megakaryocyte,hematopoietic progenitor cell,endothelial cell,embryonic brain,associated with

a special class of nuclear bodies. Regulating endothelin 1 (EDN1) expression. Activated by

calcineurin (IGF1 induced) to promote myocyte hypertrophy

14 MGI mutant phenotypes (inferred from 7 alleles) (MGI details for Gata2):

	embryogenesis	endocrine/exocrine gland	growth/size	hearing/vestibular/ear
hematopoietic system	homeostasis/metabolism	lethality-postnatal	lethality-prenatal/perinatal	life span-post-weaning/aging
nervous system	normal	renal/urinary system	reproductive system

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	IEA	--
GO:0008134	transcription factor binding	IPI	15016828
GO:0008270	zinc ion binding	IEA	--
GO:0043565	sequence-specific DNA binding	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for GATA2 (Your Favorite Gene powered by Ingenuity)

Thrombin Signaling

GeneDecks GATA2 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for GATA2

5/77 Interacting proteins for GATA2 (ENSP00000345681³) via UniProtKB, MINT, and/or STRING (see all 77 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ZFPM1	ENSP00000326630³	STRING (score=.996)
EDN1	ENSP00000368683³	STRING (score=.994)
SPI1	ENSP00000367799³	STRING (score=.993)
HDAC3	ENSP00000302967³	STRING (score=.989)
HDAC5	ENSP00000225983³	STRING (score=.983)

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5/10 Gene Ontology (GO) biological process terms (links to tree view) (see all 10 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001709	cell fate determination	IEA	--
GO:0001892	embryonic placenta development	IEA	--
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0010552	positive regulation of specific transcription from RNA polymerase II promoter	IDA	15016828

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for GATA2
5 Novoseek chemical compound relationships for GATA2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
zinc	42.90	18	11964310 (4), 7823932 (2), 10938104 (1), 10411939 (1) (see all 11)
benzidine	39.21	2	11146164 (1)
12-o-tetradecanoylphorbol 13-acetate	15.94	5	8562972 (2), 9419420 (1)
oligonucleotide	9.52	1	7541039 (1)
leucine	0.00	2	15632071 (1), 16931285 (1)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GATA2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GATA2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): BC015613

Sigma-Aldrich siRNA for GATA2

Sigma-Aldrich shRNA for GATA2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_032638

REFSEQ mRNAs for GATA2 gene (3 alternative transcripts):

NM_001145661.1 NM_001145662.1 NM_032638.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_032638

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001145661
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001145661
                                 untagged cDNA clones in CMV expression vector (see all 5): BC015613

Additional cDNA sequence:

AK314826.1 BC002557.2 BC015577.2 BC015613.2 BC018988.2 BC051272.1 BC051342.1 BT006671.1

CR621712.1 M68891.1 M77810.1

12 DOTS entries:

DT.308983 DT.100824493 DT.92330285 DT.100671217 DT.95083558 DT.100658371 DT.100824502 DT.120890052

DT.100824492 DT.120890094 DT.92413074 DT.120890059

24/180 AceView cDNA sequences (see all 180 ):

AI216622 BE348488 BQ026392 BQ022387 AI962483 BC002557 NM_032638 AI867420

CD672746 BC015613 CR621712 BE670978 BC051342 AI375813 CF144613 AI202702

BI819533 BE858858 BE671935 AI954657 BI494388 BM662402 BI195665 BX394055

highest scoring ESTs for GATA2:

AA843659 AW451201 BC002557 BC015613 BC051342 BE280815 BE410016 BE730817 BF206316 BF317089

Unigene Cluster for GATA2:

GATA binding protein 2

Hs.367725 [show with all ESTs]

Unigene Representative Sequence: NM_001145661

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for GATA2 (see all 6 )

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	·	5c	^	6	^	7	^	8a	·	8b	·	8c	^	9	^	10a	·	10b
SP1:					-		-		-												-						-
SP2:																					-		-				-
SP3:							-		-
SP4:
SP5:																											-

About this scheme

ECgene alternative splicing isoforms for GATA2

1 Ensembl transcript including schematic representation:

ENST00000341105

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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GATA2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for GATA2

¹ / ² / ³

10 probe-sets matching GATA2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1072_g_at²^{, 3}	U95-A	1	1.00	1.00	0.85	0.91	M77810	0.60	1.00	0.82	1
37194_at²^{, 3}	U95-A	1	1.00	1.00	0.99	1.14	M68891	0.80	1.00	0.91	1
1071_at²^{, 3}	U95-A	1	1.00	1.00	0.90	0.94	M77810	0.60	1.00	0.82	1
203_at²^{, 3}	U95-A	1	1.00	1.00	0.97	1.02	M68891	0.80	1.00	0.91	1
210358_x_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BC002557	0.80	1.00	0.91	1
207954_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002050	0.20	1.00	0.72	1
209710_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AL563460	0.40	1.00	0.76	1
210358_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
207954_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
209710_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks GATA2 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GACAGTTGTT

SOURCE GeneReport for Unigene cluster: Hs.367725
Expression variation in blood from EXPOLDB for GATA2
UniProtKB/Swiss-Prot: GATA2_HUMAN, P23769
Tissue specificity: Endothelial cells

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for GATA2 gene from 5/14 species (see all 14 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	GATA2¹	--	GATA binding protein 2	92.63(n) 98.93(a)	484626 XM_851997.1 XP_857090.1
chimpanzee (Pan troglodytes)	GATA2¹	--	GATA binding protein 2	99.79(n) 100(a)	460672 XM_516728.2 XP_516728.2
cow (Bos taurus)	GATA2¹	--	GATA binding protein 2	89.07(n) 96.03(a)	506809 XM_583307.3 XP_583307.2
rat (Rattus norvegicus)	Gata2¹	--	GATA binding protein 2	90.56(n) 97.5(a)	25159 NM_033442.1 NP_254277.1
mouse (Mus musculus)	Gata2^{1, 5}	6 (38.50 cM)⁵	GATA binding protein 2^{1, 5}	90(n)¹ 97.5(a)¹	14461¹ NM_008090.4¹ NP_032116.3¹ AB000096⁵ AK004551⁵ (see all 15)

About this table Species with no ortholog for GATA2

ENSEMBL Gene Tree for GATA2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for GATA2 gene

GATA4² GATA3² GATA1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/124 NCBI SNPs in GATA2 are shown (see all 124 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 84)

AB	SNP ID	Valid	Chr 3 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2713579^1,2	A,C,F,H,O	129680794(+)	`GCCTCA/GGGACG`	1	--	ng5¹		12		EU EA WA NA	1048
	rs9851497^1,2	A,C,F,H	129695216(+)	`GGCCAC/TACAAT`	1	--	ng3¹		4		EU EA WA	418
	rs3803^1,2	C,F,H,O	129682070(-)	`TTCTCC/TTCTGG`	1	--	ut3¹ ese³ trp³		8		MN EU EA WA NA	792
	rs2335052^1,2	C,F,H	129687641(-)	`CAGCAG/ACCCAC`	1	T/A	mis¹ ese³		8		EU EA WA NA	616
	rs6439129^1,2	A,C	129695463(+)	`GGGAGG/TCAGGA`	1	--	ng3¹		0	--	--	--	--
	rs2713580^1,2	A,C	129680864(+)	`CCCCTC/G/TGCAGC`	1	--	ng5¹		0	--	--	--	--
--	rs45598538^1,2	F	129682369(-)	`AGAGGC/TTGCCT`	1	--	ut3¹		2		NA	1893
--	rs45463801^1,2	F	129682006(-)	`GGCCAC/TGGCCC`	1	--	ut3¹		2		NA	1893
--	rs45479594^1,2	F	129682142(-)	`TTCCTC/TGGGAT`	1	--	ut3¹		2		NA	1892
--	rs45463895^1,2	F	129681670(-)	`GCTGAT/AGAGTT`	1	--	ut3¹		2		NA	1892

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HapMap Linkage Disequilibrium images for GATA2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 137295

10/19 Novoseek disease relationships for GATA2 gene (see all 19 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
blast crisis	56.60	3	7643449 (1), 7579412 (1), 18550858 (1)
myeloid leukemia	47.57	2	7519472 (1), 10873593 (1)
acute leukemia	43.65	9	8035609 (2), 7780155 (2), 7808006 (1), 14701703 (1) (see all 7)
myeloid leukemia chronic	42.43	5	7643449 (1), 11877047 (1), 18250304 (1), 7579412 (1) (see all 5)
lymphoblastic leukemia acute	38.10	3	7643449 (1), 11877047 (1), 7579412 (1)
leukemia	34.82	15	15748439 (5), 11877047 (3), 7579412 (2), 7643449 (1) (see all 5)
leukemia promyelocytic acute	31.51	2	11877047 (1), 11964310 (1)
t-all	21.30	1	15369140 (1)
hematologic disorders	19.76	1	16960339 (1)
anemia aplastic	18.96	8	11328281 (4), 16960339 (2), 17654061 (1)

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Human Gene Mutation Database: GATA2
Human Genome Epidemiology Navigator: GATA2 (3 documents)

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/243 PubMed articles for GATA2 gene (see all 243 ):

Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells. (PubMed id 1714909)^{1, 2, 3, 4} Lee M.-E.... Quertermous T. (1991)
Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells. (PubMed id 1370462)^{1, 3, 4} Dorfman D.M.... Orkin S.H. (1992)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle. (PubMed id 19168794)^{1, 3} Tipping A.J....Enver T. (2009)
Functional regulation of GATA-2 by acetylation. (PubMed id 15001660)^{1, 3} Hayakawa F....Saito H. (2004)
Transcription factor GATA-2 is expressed in erythroid, early myeloid, and CD34+ human leukemia-derived cell lines. (PubMed id 7519472)^{1, 3} Nagai T....Engel J.D. (1994)
Hematopoietic transcription factor GATA-2 activates transcription from HIV-1 long terminal repeat. (PubMed id 9517987)^{1, 3} Towatari M....Hamaguchi M. (1998)
Cross talk between retinoic acid signaling and transcription factor GATA-2. (PubMed id 15254248)^{1, 3} Tsuzuki S....Enver T. (2004)
Histone deacetylase 3 associates with and represses the transcription factor GATA-2. (PubMed id 11567998)^{1, 3} Ozawa Y....Saito H. (2001)
Interactions of GATA-2 with the promyelocytic leukemia zinc finger (PLZF) protein, its homologue FAZF, and the t(11;17)-generated PLZF-retinoic acid receptor alpha oncoprotein. (PubMed id 11964310)^{1, 3} Tsuzuki S. and Enver T. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2624	HGNC: 4171	AceView: GATA2	Ensembl:ENSG00000179348	euGenes: HUgn2624
ECgene: GATA2	H-InvDB: GATA2

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for GATA2	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for GATA2
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for GATA2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for GATA2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for GATA2		Antibodies for GATA2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for GATA2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (GATA2)
	Antibodies (GATA2)
	Chimera RNAi (GATA2)
	Custom Service for Mouse Mab
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Antibodies & Assays for GATA2 (GATA-2)

	Recombinant Proteins (GATA2)
	Antibodies (GATA2)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

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Antibodies for GATA2

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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GATA2 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for GATA2

Summaries
for GATA2

Genomic Location
for GATA2

Proteins
for GATA2

Protein Domains/
Families
for GATA2

Gene Function
for GATA2

Pathways & Interactions
for GATA2

Drugs & Compounds
for GATA2

Transcripts
for GATA2

Expression
for GATA2

Orthologs
for GATA2

Paralogs
for GATA2

SNPs/Variants
for GATA2

Disorders & Mutations
for GATA2

Medical News
for GATA2

Publications
for GATA2

Search for GATA2

Genome Databases showing GATA2

Other Databases showing GATA2

Specialized Databases showing GATA2

Licensable Technologies
for GATA2

Services
for GATA2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GATA2 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor GATA2

Summariesfor GATA2

Genomic Locationfor GATA2

Proteinsfor GATA2

Protein Domains/Familiesfor GATA2

Gene Functionfor GATA2

Pathways & Interactionsfor GATA2

Drugs & Compoundsfor GATA2

Transcriptsfor GATA2

Expression for GATA2

Orthologsfor GATA2

Paralogsfor GATA2

SNPs/Variantsfor GATA2

Disorders & Mutationsfor GATA2

Medical Newsfor GATA2

Publicationsfor GATA2

Search for GATA2

Genome Databases showing GATA2

Other Databases showing GATA2

Specialized Databases showing GATA2

Licensable Technologiesfor GATA2

Servicesfor GATA2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for GATA2

Summaries
for GATA2

Genomic Location
for GATA2

Proteins
for GATA2

Protein Domains/
Families
for GATA2

Gene Function
for GATA2

Pathways & Interactions
for GATA2

Drugs & Compounds
for GATA2

Transcripts
for GATA2

Expression
for GATA2

Orthologs
for GATA2

Paralogs
for GATA2

SNPs/Variants
for GATA2

Disorders & Mutations
for GATA2

Medical News
for GATA2

Publications
for GATA2

Licensable Technologies
for GATA2

Services
for GATA2