Aliases for GATA2 Gene
External Ids for GATA2 Gene
Previous GeneCards Identifiers for GATA2 Gene
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
GeneCards Summary for GATA2 Gene
GATA2 (GATA Binding Protein 2) is a Protein Coding gene. Diseases associated with GATA2 include deafness - lymphedema - leukemia and emberger syndrome. Among its related pathways are Hemostasis and G-AlphaQ Signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is GATA5.
UniProtKB/Swiss-Prot for GATA2 Gene
Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5-AGATAG-3