Aliases for GAS8 Gene
External Ids for GAS8 Gene
Previous HGNC Symbols for GAS8 Gene
Previous GeneCards Identifiers for GAS8 Gene
This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
GeneCards Summary for GAS8 Gene
GAS8 (Growth Arrest Specific 8) is a Protein Coding gene. Diseases associated with GAS8 include primary ciliary dyskinesia. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Apoptotic Pathways in Synovial Fibroblasts. GO annotations related to this gene include Rab GTPase binding.
UniProtKB/Swiss-Prot for GAS8 Gene
Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity).