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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GAS7 Gene

protein-coding   GIFtS: 61
GCID: GC17M009813

Growth Arrest-Specific 7

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Growth Arrest-Specific 71 2
MLL/GAS72
Growth Arrest-Specific Protein 72
MLL/GAS7 Fusion Protein2
GAS-73
KIAA03943

External Ids:    HGNC: 41691   Entrez Gene: 85222   Ensembl: ENSG000000072377   OMIM: 6031275   UniProtKB: O608613   

Export aliases for GAS7 gene to outside databases

Previous GC identifers: GC17M010179 GC17M010928 GC17M009756 GC17M010014 GC17M009754


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GAS7 Gene:
Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in
mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript
variants encoding proteins which vary in the N-terminus have been described. (provided by RefSeq, Jul 2008)

GeneCards Summary for GAS7 Gene: 
GAS7 (growth arrest-specific 7) is a protein-coding gene. Diseases associated with GAS7 include spastic hemiplegia, and acute myeloid leukemia with t translocation. GO annotations related to this gene include actin filament binding and sequence-specific DNA binding transcription factor activity.

UniProtKB/Swiss-Prot: GAS7_HUMAN, O60861
Function: May play a role in promoting maturation and morphological differentiation of cerebellar neurons

Gene Wiki entry for GAS7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010718.16  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GAS7 gene promoter:
         p53   Pax-6   Nkx2-5   Cdc5   NF-AT   NF-AT4   NF-AT2   FOXO4   NF-AT3   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 8): GAS7 promoter sequence
   Search SABiosciences Chromatin IP Primers for GAS7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GAS7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

GAS7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GAS7 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M009813:  view genomic region     (about GC identifiers)

Start:
9,813,926 bp from pter      End:
10,101,868 bp from pter
Size:
287,943 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GAS7_HUMAN, O60861 (See protein sequence)
Recommended Name: Growth arrest-specific protein 7  
Size: 476 amino acids; 54371 Da
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=BAA23690.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
2 PDB 3D structures from and Proteopedia for GAS7:
2LX7 (3D)        2YSH (3D)    
Secondary accessions: A8KAC2 B2RCK9 O43144 Q53Y77 Q7Z571
Alternative splicing: 4 isoforms:  O60861-3   O60861-1   O60861-2   O60861-4   

Explore the universe of human proteins at neXtProt for GAS7: NX_O60861

Explore proteomics data for GAS7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O60861

  • GAS7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GAS7 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001124303.1  NP_003635.2  NP_958836.1  NP_958839.1  

    ENSEMBL proteins: 
     ENSP00000410108   ENSP00000322608   ENSP00000407552   ENSP00000464240   ENSP00000463873  
     ENSP00000464088   ENSP00000443265   ENSP00000463527   ENSP00000463033   ENSP00000463007  
     ENSP00000462304   ENSP00000464494   ENSP00000462897   ENSP00000463551   ENSP00000379421  
     ENSP00000446214  

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    Cloud-Clone Corp. Proteins for GAS7 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle IEA--
    GO:0005737cytoplasm IEA--
    GO:0005884actin filament IEA--

    GAS7 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR001060 FCH_dom
     IPR001452 SH3_domain
     IPR001202 WW_dom

    Graphical View of Domain Structure for InterPro Entry O60861

    ProtoNet protein and cluster: O60861

    UniProtKB/Swiss-Prot: GAS7_HUMAN, O60861
    Similarity: Contains 1 FCH domain
    Similarity: Contains 1 SH3 domain
    Similarity: Contains 1 WW domain


    GAS7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GAS7_HUMAN, O60861
    Function: May play a role in promoting maturation and morphological differentiation of cerebellar neurons

         Genatlas biochemistry entry for GAS7:
    growth arrest specific gene 7,50kDa,mouse homolog

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity TAS9736752
    GO:0005515protein binding ----
    GO:0051015actin filament binding IEA--
         
    GAS7 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for GAS7:
     Decreased viability with cispl  Increased cell death in breast 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for GAS7 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GAS7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/75 Interacting proteins for GAS7 (O608612, 3 ENSP000003226084) via UniProtKB, MINT, STRING, and/or I2D (see all 75)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABI1Q8IZP02, 3, ENSP000003653124MINT-72912 I2D: score=3 STRING: ENSP00000365312
    FMNL1O954662, 3, ENSP000003292194MINT-72916 I2D: score=3 STRING: ENSP00000329219
    GAPDHP044062, 3, ENSP000002292394MINT-72922 I2D: score=3 STRING: ENSP00000229239
    KHDRBS1Q076662, 3, ENSP000003138294MINT-72907 I2D: score=3 STRING: ENSP00000313829
    RPLP0P053882, 3, ENSP000003390274MINT-72911 I2D: score=3 STRING: ENSP00000339027
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent TAS9736752
    GO:0007050cell cycle arrest TAS9736752
    GO:0008360regulation of cell shape IEA--
    GO:0030041actin filament polymerization IEA--
    GO:0030182neuron differentiation ----

    GAS7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GAS7

    Search CenterWatch for drugs/clinical trials and news about GAS7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GAS7 gene (4 alternative transcripts): 
    NM_001130831.1  NM_003644.2  NM_201432.1  NM_201433.1  

    Unigene Cluster for GAS7:

    Growth arrest-specific 7
    Hs.462214  [show with all ESTs]
    Unigene Representative Sequence: NM_201433
    18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000437099(uc002gmg.1 uc010vvc.1 uc002gmh.1 uc010vvd.1 uc002gmi.2)
    ENST00000323816(uc010coh.1) ENST00000432992 ENST00000585266 ENST00000580865
    ENST00000583882 ENST00000542249 ENST00000579158 ENST00000581112 ENST00000578456
    ENST00000581871 ENST00000580811 ENST00000584146 ENST00000579140 ENST00000578655
    ENST00000578599 ENST00000584389 ENST00000580043

    miRNA
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    8/80 QIAGEN miScript miRNA Assays for microRNAs that regulate GAS7 (see all 80):
    hsa-miR-548j hsa-miR-4254 hsa-miR-146a hsa-miR-374a hsa-miR-548a-5p hsa-miR-374b* hsa-miR-559 hsa-miR-548y
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    Additional mRNA sequence: 

    AB007854.1 AB209030.1 AJ224876.1 AK057761.1 AK225165.1 AK292987.1 AK293755.1 AK293834.1 
    AK294829.1 AK299574.1 AK307987.1 AK309722.1 AK315162.1 AY327406.1 BC001152.1 BC006454.1 
    BC113835.1 BT006891.1 

    21 DOTS entries:

    DT.87014326  DT.95106979  DT.92400005  DT.92471376  DT.120961609  DT.97800020  DT.120961650  DT.120961708 
    DT.120961668  DT.100779119  DT.120961716  DT.92471333  DT.95106989  DT.100853466  DT.92471334  DT.120961613 
    DT.120961715  DT.95106972  DT.95106980  DT.95191861  DT.97796365 

    24/369 AceView cDNA sequences (see all 369):

    AA683418 CN479858 CR608158 BF769556 AI916953 BU194048 AI693692 T33038 
    AI720127 AI189451 BM673553 AI954641 BE858058 AA411406 BP361596 AI356071 
    AA326642 AA350259 BG482273 T33023 AA309507 BI752247 N73310 AI082576 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GAS7 expression in normal human tissues (normalized intensities)      GAS7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAAAGAGCC
    GAS7 Expression
    About this image


    GAS7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Cerebral Cortex
             Fetal Neuronal Stem Cells (NSC)   
             cerebellum   
     
     Eye (Sensory Organs)    fully expand to see all 4 entries
             GABAergic Amacrine Cells Inner Nuclear Layer
             Human Retinal Pigment Epithelial Cells (HRPEpiC)   
             retinal progenitor cell e16.5   
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Pre-Sertoli Cells Testis Cord
             testis ; cells in seminiferus ducts   
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             bone marrow-derived macrophages   
     
     Gut Tube (Gastrointestinal Tract)
             Definitive endoderm-like cells ( A scalable, suspension protocol for derivation of...

    See GAS7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GAS7

    SOURCE GeneReport for Unigene cluster: Hs.462214
        SABiosciences Custom PCR Arrays for GAS7
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GAS7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for GAS7 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gas71 , 5 growth arrest specific 71, 5 91.13(n)1
    97.36(a)1
      11 (41.13 cM)5
    144571  NM_008088.41  NP_032114.21 
     674554375 
    chicken
    (Gallus gallus)
    Aves GAS71 growth arrest-specific 7 79.55(n)
    84.45(a)
      417305  XM_415577.3  XP_415577.2 
    lizard
    (Anolis carolinensis)
    Reptilia GAS76
    Uncharacterized protein
    79(a)
    1 ↔ 1
    2(109213804-109321439)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.241342 Xenopus laevis transcribed sequence with moderate similarity to protein refNP_003635.1 (H.sapiens) growth arrest-specific 7 isoform a [Homo sapiens] less 82.2(n)    BJ625620.1 
    zebrafish
    (Danio rerio)
    Actinopterygii gas71 growth arrest-specific 7 75.44(n)
    81.5(a)
      793701  XM_001333471.2  XP_001333507.2 


    ENSEMBL Gene Tree for GAS7 (if available)
    TreeFam Gene Tree for GAS7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GAS7 gene
    5 SIMAP similar genes for GAS7 using alignment to 13 protein entries:     GAS7_HUMAN (see all proteins):
    MLL/GAS7    PSTPIP1    SH3GL2    PIN1P1    SH3GL1

    GAS7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/7342 SNPs in GAS7 are shown (see all 7342)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1843770501,2
    --9802888(+) AGAATC/TGCTTG 4 -- ds50010--------
    rs47919081,2
    C,F,A--9802909(+) gtagaG/Cgttgc 4 -- ds50016Minor allele frequency- C:0.50NA WA CSA 14
    rs1455903751,2
    --9802937(+) CCACTG/TCACTC 4 -- ds50010--------
    rs1453946541,2
    --9802944(+) ACTCCA/CGCCTG 4 -- ds50010--------
    rs1899030781,2
    C--9802952(+) CTGGGC/TGACAG 4 -- ds50010--------
    rs1389879371,2
    C--9802964(+) CGAGA-/CTACTCT 4 -- ds50010--------
    rs719580261,2
    C--9802965(+) GAGAC-/CTTCTCT 4 -- ds50010--------
    rs126020991,2
    C,F,H--9802983(+) TCTCTC/ATATAT 4 -- ds50011Minor allele frequency- A:0.08EA 120
    rs47913761,2
    C,A,H--9802985(+) TCTCTA/CTATAT 4 -- ds50013Minor allele frequency- C:0.22NA EA 242
    rs1382295341,2
    --9802987(+) TCTATA/CTATAT 4 -- ds50010--------

    HapMap Linkage Disequilibrium report for GAS7 (9813926 - 10063926 bp, first 250kb of GAS7)

    Structural Variations
         Database of Genomic Variants (DGV) 10/15 variations for GAS7 (see all 15):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2715634CNV Deletion23290073
    esv2670514CNV Deletion23128226
    esv2715633CNV Deletion23290073
    nsv1978CNV Insertion18451855
    esv269561CNV Insertion20981092
    dgv38n68CNV Loss17160897
    nsv516119CNV Loss19592680
    nsv833365CNV Gain17160897
    nsv907678CNV Gain21882294
    nsv907674CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603127    OMIM disorders: --

    UniProtKB/Swiss-Prot: GAS7_HUMAN, O60861
  • Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation
    t(11;17)(q23;p13) with KMT2A/MLL1

  • 17 diseases for GAS7:    About MalaCards
    spastic hemiplegia    acute myeloid leukemia with t translocation    hemiplegia    pediatric osteosarcoma
    primary open angle glaucoma    open-angle glaucoma    spasticity    neuronitis
    osteosarcoma    glaucoma    acute leukemia    ulcerative colitis
    acute myeloid leukemia    myeloid leukemia    neuroblastoma    alzheimer's disease
    leukemia

    1 disease from the University of Copenhagen DISEASES database for GAS7:
    Spastic hemiplegia

    GAS7 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): GAS7
    Human Genome Epidemiology (HuGE) Navigator: GAS7 (8 documents)

    Export disorders for GAS7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GAS7 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with GAS7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (2010)
    2. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (2010)
    3. Genetic analysis in a Dutch study sample identifies m ore ulcerative colitis susceptibility loci and shows their additive role in dis ease risk. (PubMed id 19861958)1, 4 Festen E.A....Weersma R.K. (2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors. (PubMed id 10706619)1, 2 Megonigal M.D.... Felix C.A. (2000)
    8. gas7: A gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation. (PubMed id 9736752)1, 3 Ju Y.T....Lin-Chao S. (1998)
    9. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2 Ishikawa K....Ohara O. (1997)
    10. Human Gas7 isoforms homologous to mouse transcripts differentially induce neurite outgrowth. (PubMed id 15948147)1, 9 Chao C.C....Lu H.H. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8522 HGNC: 4169 AceView: GAS7 Ensembl:ENSG00000007237 euGenes: HUgn8522
    ECgene: GAS7 H-InvDB: GAS7

    (According to HUGE)
    About This Section
    HUGE: KIAA0394

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GAS7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for GAS7 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GAS7 gene:
    Search GeneIP for patents involving GAS7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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