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Set Analyses:

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GAS7 Gene

protein-coding GIFtS: 61
GCID: GC17M009813

Growth Arrest-Specific 7

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Growth Arrest-Specific 7¹ ²
MLL/GAS7²
Growth Arrest-Specific Protein 7²
MLL/GAS7 Fusion Protein²
GAS-7³
KIAA0394³

External Ids:	HGNC: 4169¹	Entrez Gene: 8522²	Ensembl: ENSG00000007237⁷	OMIM: 603127⁵	UniProtKB: O60861³

Export aliases for GAS7 gene to outside databases

Previous GC identifers: GC17M010179 GC17M010928 GC17M009756 GC17M010014 GC17M009754

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for GAS7 Gene:

Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in

mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript

variants encoding proteins which vary in the N-terminus have been described. (provided by RefSeq, Jul 2008)

GeneCards Summary for GAS7 Gene:

GAS7 (growth arrest-specific 7) is a protein-coding gene. Diseases associated with GAS7 include spastic hemiplegia, and pediatric osteosarcoma. GO annotations related to this gene include actin filament binding and sequence-specific DNA binding transcription factor activity.

UniProtKB/Swiss-Prot: GAS7_HUMAN, O60861

Function: May play a role in promoting maturation and morphological differentiation of cerebellar neurons

Gene Wiki entry for GAS7 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000017.11 NT_010718.17 NC_018928.2

Regulatory elements:

Regulatory transcription factor binding sites in the GAS7 gene promoter:
p53 Pax-6 Nkx2-5 Cdc5 NF-AT NF-AT4 NF-AT2 FOXO4 NF-AT3 NF-AT1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 8): GAS7 promoter sequence

Search Chromatin IP Primers for GAS7

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GAS7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.1

GAS7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GAS7 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M009813: view genomic region (about GC identifiers)

Start:	9,813,926 bp from pter	End:	10,101,868 bp from pter
Size:	287,943 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: GAS7_HUMAN, O60861 (See protein sequence)

Recommended Name: Growth arrest-specific protein 7

Size: 476 amino acids; 54371 Da

Sequence caution: Sequence=BAA23690.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;

2 PDB 3D structures from and Proteopedia for GAS7:

2LX7 (3D)

2YSH (3D)

Secondary accessions: A8KAC2 B2RCK9 O43144 Q53Y77 Q7Z571

Alternative splicing: 4 isoforms: O60861-3 O60861-1 O60861-2 O60861-4

Explore the universe of human proteins at neXtProt for GAS7: NX_O60861

Explore proteomics data for GAS7 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See GAS7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (4 alternative transcripts):

NP_001124303.1 NP_003635.2 NP_958836.1 NP_958839.1

ENSEMBL proteins:

ENSP00000410108 ENSP00000322608 ENSP00000407552 ENSP00000464240 ENSP00000463873

ENSP00000464088 ENSP00000443265 ENSP00000379421 ENSP00000463527 ENSP00000462304

ENSP00000464494 ENSP00000462897 ENSP00000463551 ENSP00000446214

GAS7 Human Recombinant Protein Products:

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GAS7 Assay Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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3 InterPro protein domains:

IPR001060 FCH_dom

IPR001452 SH3_domain

IPR001202 WW_dom

Graphical View of Domain Structure for InterPro Entry O60861

ProtoNet protein and cluster: O60861

UniProtKB/Swiss-Prot: GAS7_HUMAN, O60861

Similarity: Contains 1 FCH domain

Similarity: Contains 1 SH3 domain

Similarity: Contains 1 WW domain

GAS7 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: GAS7_HUMAN, O60861

Function: May play a role in promoting maturation and morphological differentiation of cerebellar neurons

Genatlas biochemistry entry for GAS7:

growth arrest specific gene 7,50kDa,mouse homolog

Gene Ontology (GO): 3 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	sequence-specific DNA binding transcription factor activity	TAS	9736752
GO:0005515	protein binding	--	--
GO:0051015	actin filament binding	IEA	--

GAS7 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for GAS7:

Decreased viability with cispl

Increased cell death in breast

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GAS7

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for GAS7

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GAS7

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GAS7

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		Block miRNA regulation of human, mouse, rat GAS7 using miScript Target Protectors
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		hsa-miR-548j hsa-miR-4254 hsa-miR-146a hsa-miR-374a hsa-miR-548a-5p hsa-miR-374b* hsa-miR-559 hsa-miR-548y

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for GAS7
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GAS7

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

GAS7_HUMAN, O60861: Cytoplasm (By similarity)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	3
cytoskeleton	2
cytosol	1
golgi apparatus	1

About this image

Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001726	ruffle	IEA	--
GO:0005737	cytoplasm	IEA	--
GO:0005884	actin filament	IEA	--

GAS7 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for GAS7
Interactions:

Search GeneGlobe Interaction Network for GAS7

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for GAS7 (O60861^{2, 3} ENSP00000322608⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 130)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ABI1	Q8IZP0²^,³, ENSP00000365312⁴	MINT-72912 I2D: score=3 STRING: ENSP00000365312
FMNL1	O95466²^,³, ENSP00000329219⁴	MINT-72916 I2D: score=3 STRING: ENSP00000329219
GAPDH	P04406²^,³, ENSP00000229239⁴	MINT-72922 I2D: score=3 STRING: ENSP00000229239
KHDRBS1	Q07666²^,³, ENSP00000313829⁴	MINT-72907 I2D: score=3 STRING: ENSP00000313829
RPLP0	P05388²^,³, ENSP00000339027⁴	MINT-72911 I2D: score=3 STRING: ENSP00000339027

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Gene Ontology (GO): Selected biological process terms (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006355	regulation of transcription, DNA-templated	TAS	9736752
GO:0007050	cell cycle arrest	TAS	9736752
GO:0008360	regulation of cell shape	IEA	--
GO:0030041	actin filament polymerization	IEA	--
GO:0030182	neuron differentiation	--	--

GAS7 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for GAS7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for GAS7 gene (4 alternative transcripts):

NM_001130831.1 NM_003644.2 NM_201432.1 NM_201433.1

Unigene Cluster for GAS7:

Growth arrest-specific 7

Hs.462214 [show with all ESTs]

Unigene Representative Sequence: NM_201433

Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):

ENST00000437099(uc002gmg.1 uc010vvc.1 uc002gmh.1 uc010vvd.1 uc002gmi.2)

ENST00000323816(uc010coh.1) ENST00000432992 ENST00000585266 ENST00000580865

ENST00000583882 ENST00000542249 ENST00000396115(uc002gmj.1) ENST00000579158

ENST00000581112 ENST00000578456 ENST00000581871 ENST00000580811 ENST00000584146

ENST00000579140 ENST00000578655 ENST00000578599 ENST00000584389

miRNA Products:		Block miRNA regulation of human, mouse, rat GAS7 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate GAS7 (see all 80):
		hsa-miR-548j hsa-miR-4254 hsa-miR-146a hsa-miR-374a hsa-miR-548a-5p hsa-miR-374b* hsa-miR-559 hsa-miR-548y

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		Pre-validated RT² qPCR Primer Assay in human, mouse, rat GAS7
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		QuantiFast Probe-based Assays in human, mouse, rat GAS7

Additional mRNA sequence:

AB007854.1 AB209030.1 AJ224876.1 AK057761.1 AK225165.1 AK292987.1 AK293755.1 AK293834.1

AK294829.1 AK299574.1 AK307987.1 AK309722.1 AK315162.1 AY327406.1 BC001152.1 BC006454.1

BC113835.1 BT006891.1

21 DOTS entries:

DT.87014326 DT.95106979 DT.92400005 DT.92471376 DT.120961609 DT.97800020 DT.120961650 DT.120961708

DT.120961668 DT.100779119 DT.120961716 DT.92471333 DT.95106989 DT.100853466 DT.92471334 DT.120961613

DT.120961715 DT.95106972 DT.95106980 DT.95191861 DT.97796365

Selected AceView cDNA sequences (see all 369):

BG056686 AW593485 AA309507 AA350259 AA600973 BQ879120 CD368825 AI417814

AI082576 BE711134 AI356071 BC006454 AA434413 AI371807 BE327411 AI806848

H85959 BM684183 AI276703 BE671619 AI802261 BE326370 BT006891 BF768916

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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GAS7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TTAAAGAGCC

About this image

GAS7 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 6) fully expand


Brain (Nervous System) fully expand to see all 4 entries
Cerebral Cortex

Eye (Sensory Organs) fully expand to see all 2 entries
GABAergic Amacrine Cells Inner Nuclear Layer
Retina

Testis (Reproductive System)
Pre-Sertoli Cells Testis Cord

Neurons
GABAergic Amacrine Cells Inner Nuclear Layer

Bone (Muscoskeletal System)
Bone Marrow

GAS7 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

GAS7 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.462214

Custom PCR Arrays for GAS7

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GAS7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for GAS7 gene from Selected species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Gas7^{1 , 5}	growth arrest specific 7^{1, 5}	91.13(n)¹ 97.36(a)¹		11 (41.13 cM)⁵ 14457¹ NM_008088.5¹ NP_032114.2¹ 67455437⁵
chicken (Gallus gallus)	Aves	GAS7¹	growth arrest-specific 7	79.55(n) 84.45(a)		417305 XM_004946059.1 XP_004946116.1
lizard (Anolis carolinensis)	Reptilia	GAS7⁶	growth arrest-specific 7	79(a)	1 ↔ 1	2(109213804-109321439)
African clawed frog (Xenopus laevis)	Amphibia	Xl.24134²	Xenopus laevis transcribed sequence with moderate similarity more	82.2(n)		BJ625620.1
zebrafish (Danio rerio)	Actinopterygii	gas7a¹	growth arrest-specific 7a	76.17(n) 82.95(a)		793701 NM_001278819.1 NP_001265748.1

ENSEMBL Gene Tree for GAS7 (if available)
TreeFam Gene Tree for GAS7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for GAS7 gene

4 SIMAP similar genes for GAS7 using alignment to 9 protein entries: GAS7_HUMAN (see all proteins):

MLL/GAS7 SH3GL2 PIN1P1 SH3GL1

GAS7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs184377050^1,2		--	9802888(+)	`AGAATC/TGCTTG`	4	--	ds500¹		0	--	--	--	--
rs4791908^1,2	C,F,A	--	9802909(+)	`gtagaG/Cgttgc`	4	--	ds500¹		6		NA WA CSA	14
rs145590375^1,2		--	9802937(+)	`CCACTG/TCACTC`	4	--	ds500¹		0	--	--	--	--
rs145394654^1,2		--	9802944(+)	`ACTCCA/CGCCTG`	4	--	ds500¹		0	--	--	--	--
rs189903078^1,2	C	--	9802952(+)	`CTGGGC/TGACAG`	4	--	ds500¹		0	--	--	--	--
rs138987937^1,2	C	--	9802964(+)	`CGAGA-/CTACTCT`	4	--	ds500¹		0	--	--	--	--
rs71958026^1,2	C	--	9802965(+)	`GAGAC-/CTTCTCT`	4	--	ds500¹		0	--	--	--	--
rs12602099^1,2	C,F,H	--	9802983(+)	`TCTCTC/ATATAT`	4	--	ds500¹		1		EA	120
rs4791376^1,2	C,A,H	--	9802985(+)	`TCTCTA/CTATAT`	4	--	ds500¹		3		NA EA	242
rs138229534^1,2		--	9802987(+)	`TCTATA/CTATAT`	4	--	ds500¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for GAS7 (9813926 - 10063926 bp, first 250kb of GAS7)

Structural Variations
Database of Genomic Variants (DGV) Selected variations for GAS7 (see all 15): About this table

Variant ID	Type	Subtype	PubMed ID
esv2715634	CNV	Deletion	23290073
esv2670514	CNV	Deletion	23128226
esv2715633	CNV	Deletion	23290073
nsv1978	CNV	Insertion	18451855
esv269561	CNV	Insertion	20981092
dgv38n68	CNV	Loss	17160897
nsv516119	CNV	Loss	19592680
nsv833365	CNV	Gain	17160897
nsv907678	CNV	Gain	21882294
nsv907674	CNV	Gain	21882294

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing GAS7

DNA2.0 Custom Variant and Variant Library Synthesis for GAS7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 603127 OMIM disorders: --

UniProtKB/Swiss-Prot: GAS7_HUMAN, O60861

Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation

t(11;17)(q23;p13) with KMT2A/MLL1

Selected diseases for GAS7 (see all 23):
About MalaCards

spastic hemiplegia pediatric osteosarcoma hemiplegia acute myeloid leukemia

open-angle glaucoma primary open angle glaucoma glaucoma spasticity

neuronitis osteosarcoma myeloid leukemia acute leukemia

ulcerative colitis leukemia ataxia neuroblastoma

hypertension tonsillitis retinitis alzheimer's disease

1 disease from the University of Copenhagen DISEASES database for GAS7:

Spastic hemiplegia

GAS7 for disorders About GeneDecksing

Congresses - knowledge worth sharing:
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
Genetic Association Database (GAD): GAS7
Human Genome Epidemiology (HuGE) Navigator: GAS7 (8 documents)

Export disorders for GAS7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for GAS7 gene, integrated from 10 sources (see all 37):
(articles sorted by number of sources associating them with GAS7)

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Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)^{1, 4} Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)^{1, 4} Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk. (PubMed id 19861958)^{1, 4} Festen E.A....Weersma R.K. (Am. J. Gastroenterol. 2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (Mol. Med. 2010)
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)^{1, 4} Bailey S.D....Anand S. (Diabetes Care 2010)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors. (PubMed id 10706619)^{1, 2} Megonigal M.D.... Felix C.A. (Proc. Natl. Acad. Sci. U.S.A. 2000)
gas7: A gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation. (PubMed id 9736752)^{1, 3} Ju Y.T....Lin-Chao S. (Proc. Natl. Acad. Sci. U.S.A. 1998)
Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)^{1, 2} Ishikawa K.... Ohara O. (DNA Res. 1997)
Human Gas7 isoforms homologous to mouse transcripts differentially induce neurite outgrowth. (PubMed id 15948147)^{1, 9} Chao C.C....Lu H.H. (J. Neurosci. Res. 2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 8522	HGNC: 4169	AceView: GAS7	Ensembl:ENSG00000007237	euGenes: HUgn8522
ECgene: GAS7	H-InvDB: GAS7

(According to HUGE)
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HUGE: KIAA0394

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for GAS7	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for GAS7	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for GAS7 gene
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Patent Information for GAS7 gene:
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GAS7 Gene

Growth Arrest-Specific 7

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Growth Arrest-Specific 7

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