Aliases for GART Gene
External Ids for GART Gene
Previous HGNC Symbols for GART Gene
Previous GeneCards Identifiers for GART Gene
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for GART Gene
GART (Phosphoribosylglycinamide Formyltransferase, Phosphoribosylglycinamide Synthetase, Phosphoribosylaminoimidazole Synthetase) is a Protein Coding gene. Diseases associated with GART include benign mesothelioma. Among its related pathways are Signaling by GPCR and Heart Development. GO annotations related to this gene include methyltransferase activity and phosphoribosylformylglycinamidine cyclo-ligase activity.