Aliases for GANAB Gene
External Ids for GANAB Gene
Previous GeneCards Identifiers for GANAB Gene
GeneCards Summary for GANAB Gene
GANAB (Glucosidase II Alpha Subunit) is a Protein Coding gene. Among its related pathways are Metabolism and Transport to the Golgi and subsequent modification. GO annotations related to this gene include poly(A) RNA binding and hydrolase activity, hydrolyzing O-glycosyl compounds. An important paralog of this gene is MGAM.
UniProtKB/Swiss-Prot for GANAB Gene
Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins.
Glycosylases are a group of enzymes that includes glucosidases, mannosidases and heparanases. There are two glucosidase subtypes, both found in the gut. They hydrolyze terminal (1,4)alpha-glucosidic linkages and (1,6)beta-glucosidic linkages, liberating alpha-glucose and beta-glucose.