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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GALR3 Gene

protein-coding   GIFtS: 62
GCID: GC22P038219

Galanin Receptor 3

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Galanin Receptor 31 2
GAL3-R2 3
GALR-32 3
Galanin Receptor Type 32
Galanin Receptor, Family Member 32
GALNR33

External Ids:    HGNC: 41341   Entrez Gene: 84842   Ensembl: ENSG000001283107   OMIM: 6036925   UniProtKB: O607553   

Export aliases for GALR3 gene to outside databases

Previous GC identifers: GC22P034833 GC22P036462 GC22P036543 GC22P021186


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GALR3 Gene:
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain
processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors
that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in
many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts (provided by RefSeq, Jul 2008)

GeneCards Summary for GALR3 Gene: 
GALR3 (galanin receptor 3) is a protein-coding gene. Diseases associated with GALR3 include alcoholism, and alzheimer's disease, and among its related super-pathways are Class A/1 (Rhodopsin-like receptors) and Peptide GPCRs. GO annotations related to this gene include galanin receptor activity. An important paralog of this gene is SSTR3.

UniProtKB/Swiss-Prot: GALR3_HUMAN, O60755
Function: Receptor for the hormone galanin

summary for GALR3 Gene:
Galanin is widely distributed in the central and peripheral nervous systems and the endocrine system. Three
different galanin receptors (GAL1-3) have been identified which are Gi/o-protein-coupled. They are highly
expressed in hypothalamic nuclei and the brainstem. In addition, they are found in proliferating zones of
the fetal and adult brain and in peripheral tissues including the pancreas, heart, skin and gastrointestinal
tract. Galanin receptors mediate a variety of physiological functions including inhibition of
glucose-induced insulin secretion, stimulation of growth hormone release and modulation of gastrointestinal
motility. These receptors also modulate neuronal functions including memory, nociception, spinal reflexes
and feeding. Disruption of galanin expression or galanin receptor signaling is seen in many multifactoral
conditions, suggesting a role in the development and/or pathology of certain diseases. These include
Alzheimer's disease, epilepsy, diabetes, alcoholism, neuropathic pain and cancer.

Gene Wiki entry for GALR3 (Galanin receptor 3) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.2  NT_011520.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GALR3 gene promoter:
         E2F-4   E2F-3a   E2F-5   Pax-5   E2F-2   GATA-2   Max   PPAR-gamma1   E2F-1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGALR3 promoter sequence
   Search SABiosciences Chromatin IP Primers for GALR3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GALR3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q113.1

GALR3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GALR3 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P038219:  view genomic region     (about GC identifiers)

Start:
38,219,389 bp from pter      End:
38,221,502 bp from pter
Size:
2,114 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GALR3_HUMAN, O60755 (See protein sequence)
Recommended Name: Galanin receptor type 3  
Size: 368 amino acids; 39573 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: Q53YJ4

Explore the universe of human proteins at neXtProt for GALR3: NX_O60755

Explore proteomics data for GALR3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O60755

  • GALR3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GALR3 Protein Expression
    REFSEQ proteins: NP_003605.1  
    ENSEMBL proteins: 
     ENSP00000249041  
    Reactome Protein details: O60755
    Human Recombinant Protein Products for GALR3: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GALR3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--

    GALR3 for ontologies           About GeneDecksing



    GALR3 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GALR: GPCR / Class A : Galanin receptors

    IUPHAR Guide to PHARMACOLOGY protein family classification: GAL3 receptor 
    Galanin receptors

    4 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR003908 Galnin_3_rcpt
     IPR000405 Galanin_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry O60755

    ProtoNet protein and cluster: O60755

    2 Blocks protein domains:
    IPB000405 Galanin receptor signature
    IPB003908 Galanin 3 receptor signature


    UniProtKB/Swiss-Prot: GALR3_HUMAN, O60755
    Similarity: Belongs to the G-protein coupled receptor 1 family


    GALR3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GALR3_HUMAN, O60755
    Function: Receptor for the hormone galanin

         Genatlas biochemistry entry for GALR3:
    galanin receptor 3,G protein coupled receptor superfamily,linked to voltage gated calcium channel,expressed in
    testis,adrenal gland,pancreas,predominantly signaling through inhibition of adenylate cyclase

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity ----
    GO:0004966galanin receptor activity IEA--
         
    GALR3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for GALR3:
     Increased cell number in G1, a 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Galr3):
     homeostasis/metabolism 

    GALR3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Galr3tm1Lex for GALR3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for GALR3 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GALR3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)0.71
    G alpha (i) signalling events0.46
    GPCR ligand binding0.71
    GPCRs, Class A Rhodopsin-like0.41
    Peptide ligand-binding receptors0.60
    Neuroactive ligand-receptor interaction0.37
    2Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q
    Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q0.46
    Peptide GPCRs0.46
    3Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for GALR3
        Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q


    2 BioSystems Pathways for GALR3
        GPCRs, Class A Rhodopsin-like
    Peptide GPCRs

    5/7        Reactome Pathways for GALR3 (see all 7)
        GPCR downstream signaling
    Peptide ligand-binding receptors
    Signal Transduction
    Signaling by GPCR
    G alpha (i) signalling events


    1         Kegg Pathway  (Kegg details for GALR3):
        Neuroactive ligand-receptor interaction


    GALR3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GALR3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/144 Interacting proteins for GALR3 (ENSP000002490414) via UniProtKB, MINT, STRING, and/or I2D (see all 144)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADCY1ENSP000002973234STRING: ENSP00000297323
    ADCY2ENSP000003429524STRING: ENSP00000342952
    ADCY4ENSP000003121264STRING: ENSP00000312126
    ADCY5ENSP000004193614STRING: ENSP00000419361
    ADCY7ENSP000002542354STRING: ENSP00000254235
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0007194negative regulation of adenylate cyclase activity IEA--
    GO:0007218neuropeptide signaling pathway TAS9722565
    GO:0007268synaptic transmission TAS9722565
    GO:0007611learning or memory TAS9722565

    GALR3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    GALR3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for GALR3 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    M617Selective GAL1 agonist[860790-38-1]
    Galanin (1-29) (rat, mouse) Non-selective galanin receptor agonist[114547-31-8]
    M40 Potent, non-selective galanin receptor antagonist [143896-17-7]
    M 1145Potent and selective GAL2 agonist[1172089-00-7]
    M871Selective GAL2 antagonist[908844-75-7]

    10/28 IUPHAR Ligands for GALR3 (GAL3 receptor) (see all 28)    About this table 
    LigandTypeActionAffinityPubmed IDs
    [125I][Tyr26]galanin (pig)
    AgonistAgonist8.659722565
    [125I][Tyr26]galanin (human)
    AgonistAgonist8.659880084
    galanin
    AgonistFull agonist7.91 - 8.359722565 19467704 21333705 9880084
    SNAP 398299
    AntagonistAntagonist8.2716287967
    M32
    AntagonistAntagonist8.229880084 9722565
    C7
    AntagonistAntagonist8.089880084 9722565
    galanin-like peptide
    AgonistAgonist815944009
    galanin
    AgonistFull agonist7.929832121
    J20 (galanin analogue)
    AgonistAgonist7.8923600864
    M35
    AntagonistAntagonist7.8 - 7.849880084 9722565

    1 Novoseek inferred chemical compound relationship for GALR3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 0 1 9832121 (1)

    Search CenterWatch for drugs/clinical trials and news about GALR3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GALR3 gene: 
    NM_003614.1  

    Unigene Cluster for GALR3:

    Galanin receptor 3
    Hs.158353  [show with all ESTs]
    Unigene Representative Sequence: AF073799
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000249041(uc003aub.1)

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    Additional mRNA sequence: 

    AF067733.1 AF073799.1 AY587582.1 

    1 DOTS entry:

    DT.91751733 

    8 AceView cDNA sequences:

    AF073799 AF067733 NM_003614 AY587582 BF116239 BQ187252 BF512731 BX280441 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GALR3 expression in normal human tissues (normalized intensities)      GALR3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGCGGTGG
    GALR3 Expression
    About this image


    GALR3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 18 entries
             Thalamus
             Septum   
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             Dorsal Horn   

    See GALR3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GALR3

    SOURCE GeneReport for Unigene cluster: Hs.158353
        SABiosciences Expression via Pathway-Focused PCR Array including GALR3: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GALR3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GALR3 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Galr31 , 5 galanin receptor 31, 5 87.44(n)1
    92.52(a)1
      15 (37.70 cM)5
    144291  NM_015738.21  NP_056553.21 
     790418855 
    chicken
    (Gallus gallus)
    Aves GALR31 galanin receptor 3 68.1(n)
    65.89(a)
      427904  NM_001130585.1  NP_001124057.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    49(a)
    44(a)
    many ↔ many
    many ↔ many
    5(24039165-24052404)
    2(113170432-113182116)
    zebrafish
    (Danio rerio)
    Actinopterygii --
    CU681846.16
    Uncharacterized protein
    45(a)
    44(a)
    many ↔ many
    many ↔ many
    12(37262652-37266591)
    3(43140041-43147900)
    fruit fly
    (Drosophila melanogaster)
    Insecta AlstR3 G-protein coupled receptor protein
    signaling pathway more
    34(a)   1 3E1   --
    worm
    (Caenorhabditis elegans)
    Secernentea ZK455.33 G-protein coupled receptor 30(a)   X(11363821-11367302)   --


    ENSEMBL Gene Tree for GALR3 (if available)
    TreeFam Gene Tree for GALR3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GALR3 gene
    SSTR32  OPRL12  OPRK12  NPBWR12  OPRD12  KISS1R2  GALR12  SSTR42  
    GALR22  SSTR52  MCHR22  SSTR12  SSTR22  MCHR12  OPRM12  NPBWR22  
    10 SIMAP similar genes for GALR3 using alignment to 1 protein entry:     GALR3_HUMAN:
    GALR2    GALR1    OPRM1    SSTR4    KISS1R    NPBWR2
    OPRD1    CYSLTR2    KPG_011    OPRK1

    GALR3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/121 SNPs in GALR3 are shown (see all 121)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
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    ----------
    rs126277921,2
    H--38217481(+) cactgA/Caacct 1 -- us2k10--------
    rs1895132361,2
    --38217692(+) ACCGCA/GCCCAG 1 -- us2k10--------
    rs711950581,2
    C--38217705(+) TTTTT-/TTTGAG 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs622350711,2
    C,F--38217751(+) ATCACC/TTGGGC 1 -- us2k11Minor allele frequency- T:0.04NA 120
    rs1932080871,2
    --38217899(+) GAGACA/GAGGTT 1 -- us2k10--------
    rs1843824741,2
    C--38217912(+) GCCACA/TTTGGC 1 -- us2k10--------
    rs59955021,2
    C,F,A--38217935(+) gaattT/Cctggc 1 -- us2k16Minor allele frequency- C:0.30NA CSA 10
    rs1893137341,2
    C--38218005(+) ATGCCC/TGGCCT 1 -- us2k10--------
    rs1813504901,2
    --38218151(+) AAATCA/GCAGAG 1 -- us2k10--------
    rs1858082961,2
    --38218207(+) AGCAAC/TGCAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GALR3 (38219389 - 38221502 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for GALR3:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv4966n71CNV Loss21882294
    nsv915035CNV Loss21882294
    dgv4967n71CNV Loss21882294
    dgv4965n71CNV Loss21882294
    dgv1406e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603692    OMIM disorders: --

    6 diseases for GALR3:    About MalaCards
    alcoholism    alzheimer's disease    narcolepsy    noma
    neuronitis    squamous cell carcinoma


    GALR3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    2 Novoseek inferred disease relationships for GALR3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pathological processes 44.4 1 18500647 (1)
    alzheimers disease 40.1 3 18500647 (1), 19159918 (1)

    Genetic Association Database (GAD): GALR3
    Human Genome Epidemiology (HuGE) Navigator: GALR3 (4 documents)

    Export disorders for GALR3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GALR3 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with GALR3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3. (PubMed id 9832121)1, 2, 3, 9 Kolakowski L.F. Jr.... O'Dowd B.F. (1998)
    2. Cloned human and rat galanin GALR3 receptors: pharmacology and activation of G-protein inwardly rectifying K+ channels. (PubMed id 9722565)1, 2, 3 Smith K.E....Jones K.A. (1998)
    3. Alcoholism is associated with GALR3 but not two other galanin receptor genes. (PubMed id 17083333)1, 4, 9 Belfer I....Enoch M.A. (2007)
    4. Structural organization and chromosomal localization of three human galanin receptor genes. (PubMed id 9928159)1, 2, 9 Iismaa T.P.... Shine J. (1998)
    5. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PubMed id 20677014)1, 4 Shimada M....Tokunaga K. (2010)
    6. Comprehensive copy number variant (CNV) analysis of n euronal pathways genes in psychiatric disorders identifies rare variants within patients. (PubMed id 20398908)1, 4 Saus E....Estivill X. (2010)
    7. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1, 4 GratacA^s M....Carracedo A. (2008)
    8. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
    9. A polymorphism in the human GALR3 galanin receptor gene (GALNR3). (PubMed id 10441207)1, 9 Lapsys N.M....Iismaa T.P. (1999)
    10. Galanin and its three receptors in human pituitary ade noma. (PubMed id 22889491)1 Tofighi R....Hulting A.L. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8484 HGNC: 4134 AceView: GALR3 Ensembl:ENSG00000128310 euGenes: HUgn8484
    ECgene: GALR3 Kegg: 8484 H-InvDB: GALR3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GALR3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GALR3 gene:
    Search GeneIP for patents involving GALR3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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