GALNT6 Gene
protein-coding GIFtS: 57
GCID: GC12M051769
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|
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase...
| |
Aliases for GALNT6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| UDP-N-Acetyl-Alpha-D-Galactosamine:PolypeptideN-Acetylgalactosaminyltransferase 6 (GalNAc-T6)1 2 | | GalNAcT62 5 | | Polypeptide GalNAc Transferase 62 3 | | GALNAC-T62 | | Protein-UDP Acetylgalactosaminyltransferase 62 3 | | GalNAc Transferase 62 | | Pp-GaNTase 62 3 | | Polypeptide N-Acetylgalactosaminyltransferase 62 | | UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 62 3 | | UDP-N-Acetyl-Alpha-D-Galactosamine: PolypeptideN-Acetylgalactosaminyltransferase 62 | | EC 2.4.1.413 8 | | GalNAc-T63 |
Export aliases for GALNT6 gene to outside databasesPrevious GC identifers: GC12M051903 GC12M051463 GC12M050033 GC12M048778 |
Summaries for GALNT6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for GALNT6: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase(GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus bycatalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by anN-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNActransferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substratespecificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitroand is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetalfibronectin. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: GALT6_HUMAN, Q8NCL4Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of anN-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. May participate insynthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptides Gene Wiki entry for GALNT6
|
Genomic Views for GALNT6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GALNT6 gene promoter: C/EBPbeta p53 AML1a MZF-1 POU2F1 POU2F1a ATF6 En-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for GALNT6
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GALNT6 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13 Ensembl cytogenetic band: 12q13.13 HGNC cytogenetic band: 12q13GALNT6 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M051769: view genomic region
(about GC identifiers)
Start:
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51,745,682 bp from pter |
End:
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51,785,200 bp from pter |
Size:
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39,519 bases |
Orientation:
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minus strand |
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Proteins for GALNT6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: GALT6_HUMAN, Q8NCL4 (See
protein sequence)Recommended Name: Polypeptide N-acetylgalactosaminyltransferase 6 Size: 622 amino acids; 71159 Da
Cofactor: Manganese (By similarity)
Cofactor: Calcium (By similarity)
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)
Sequence caution: Sequence=BAB15297.1; Type=Erroneous initiation;
Secondary accessions: Q8IYH4 Q9H6G2 Q9UIV5Explore the universe of human proteins at neXtProt for GALNT6: NX_Q8NCL4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NCL4 4/14 DME Specific Peptides for GALNT6 (Q8NCL4) (see all 14)
GALNT6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_009141.2 ENSEMBL proteins: ENSP00000444171 ENSP00000348668 Reactome Protein details: Q8NCL4 Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
GALNT6 for ontologies About GeneDecksing
GALNT6 Antibody Products: Assay Products for GALNT6: |
Protein
Domains / Families for GALNT6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GALNT6 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NCL4ProtoNet protein and cluster: Q8NCL4 2 Blocks protein families: IPB000772 Ricin B lectin domain IPB001173 Glycosyl transferase
UniProtKB/Swiss-Prot: GALT6_HUMAN, Q8NCL4Domain: There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also calledGT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain(domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding (Bysimilarity)Domain: The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity (By similarity)Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamilySimilarity: Contains 1 ricin B-type lectin domain |
Function for GALNT6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: GALT6_HUMAN, Q8NCL4Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of anN-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. May participate insynthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptidesCatalytic activity: UDP-N-acetyl-alpha-D-galactosamine + polypeptide = UDP +N-acetyl-alpha-D-galactosaminyl-polypeptide Genatlas biochemistry entry for GALNT6:galactosamine Enzyme Number (IUBMB): EC 2.4.1.411 2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GALNT6 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GALNT6 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: GALNT6 (NM_007210) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GALNT6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GALNT6  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GALNT6 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity |
IEA | -- | | GO:0016757 | transferase activity, transferring glycosyl groups |
-- | -- | | GO:0030246 | carbohydrate binding |
-- | -- |
GALNT6 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for GALNT6: Animal Models: 1 MGI phenotypic allele for Galnt6 (no phenotypes)
GALNT6 for phenotypes About GeneDecksing
|
Pathways & Interactions for GALNT6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein | | | 2 | Asparagine N-linked glycosylation | | | 3 | Metabolism | |
Pathway sources See GeneCards unified pathways Show all pathways
3
Reactome Pathways for GALNT6
2
Kegg Pathways (Kegg details for GALNT6): UniProtKB/Swiss-Prot: GALT6_HUMAN, Q8NCL4Pathway: Protein modification; protein glycosylation
GALNT6 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GALNT6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/41 Interacting proteins for GALNT6 (Q8NCL43 ENSP000003486684) via UniProtKB, MINT, STRING, and/or I2D (see all 41) About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
GALNT6 for ontologies About GeneDecksing
|
Drugs & Compounds for GALNT6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for GALNT6
5 HMDB Compounds for GALNT6 About this table Search CenterWatch for drugs/clinical trials and news about GALNT6 / GALT6 
|
Transcripts for GALNT6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for GALNT6 gene: NM_007210.3 Unigene Cluster for GALNT6: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) Hs.505575 [show with all ESTs]Unigene Representative Sequence: AB2658202 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000543196(uc001ryk.2 uc010snh.1) ENST00000356317(uc001ryj.1 uc009zma.1 uc001ryl.1)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GALNT6 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GALNT6 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: GALNT6 (NM_007210) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GALNT6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GALNT6  |
Additional cDNA sequence: AB265820.1 AK025961.1 AK074658.1 AK296852.1 BC035822.1 BC114505.1 BC114949.1 Y08565.1 8 DOTS entries: DT.100752395 DT.121176470 DT.210421 DT.101966657 DT.121176489 DT.101967657 DT.100020935 DT.100748901 24/100 AceView cDNA sequences (see all 100): BQ012677 CA437877 BM807129 AA641456 BU678306 AA515416 AA373086 AK092496 AL118633 BC035822 BQ012333 BU678329 BF914323 BQ012827 CB141827 AA287796 NM_007210 BQ278673 AI623204 AI335787 BX490240 AI954111 AL700342 Y08565 GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for GALNT6 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | · | 7f | · | 7g | · | 7h | ^ | 8 | ^ | 9 | ^ | 10 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | |
| SP1: | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for GALNT6
|
Expression for GALNT6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GALNT6 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GCTGCGCAGA
About this image See GALNT6 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GALNT6
SOURCE GeneReport for Unigene cluster: Hs.505575 UniProtKB/Swiss-Prot: GALT6_HUMAN, Q8NCL4Tissue specificity: Expressed in placenta and trachea. Weakly expressed in brain and pancreas. Expressed in fibroblast.Weakly or not expressed in lung, liver, muscle, kidney, spleen, thymus, prostate, testis, ovary, intestine, colon,leukocyte, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland and bone marrow SABiosciences Expression via Pathway-Focused PCR Array including GALNT6:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GALNT6 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GALNT6 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GALNT6 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GALNT6 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GALNT6 |
Orthologs for GALNT6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for GALNT6 gene from 6/18 species (see all 18) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
GALNT61 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase more |
74.95(n) 76.45(a) |
  |
429501 NM_001031578.1 NP_001026749.1 |
lizard (Anolis carolinensis) |
Reptilia |
GALNT66 |
-- |
75(a) |
1 ↔ 1 |
2(67732484-67765547) |
African clawed frog (Xenopus laevis) |
Amphibia |
CF289904.12 |
-- |
73.88(n) |
  |
CF289904.1 |
zebrafish (Danio rerio) |
Actinopterygii |
CK235970.12 |
-- |
81.16(n) |
  |
324272 CK235970.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
GalNAc-T13 |
polypeptide N-acetylgalactosaminyltransferase |
40(a) (best of 4) |
  |
52A6 -- |
worm (Caenorhabditis elegans) |
Secernentea |
Y39E4B.12c3 |
-- |
45(a) (best of 4) |
  |
III(13259420-13275737) -- |
ENSEMBL Gene Tree for GALNT6 (if available) TreeFam Gene Tree for GALNT6 (if available)  |
Paralogs for GALNT6 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for GALNT6 gene
- POC1B-GALNT42 GALNT122 GALNT52 GALNT72 GALNT12 GALNTL62 GALNT142 GALNTL52
- GALNT32 GALNT22 GALNT102 GALNT42 GALNT132 GALNT162 GALNT112
18/25 SIMAP similar genes for GALNT6 using alignment to 3 protein entries: GALT6_HUMAN (see all proteins)
(see all similar genes):GALNT3 GALNTL5 GALNT1 GALNT4 POC1B-GALNT4 GALNTL6 GALNT13 GalNAc-T10 GALNT2 GalNAc-T16 GALNT12 GALNT10 GALNT5 GALNT11 GALNT14 GALNT16 GALNTL1 GALNT9
GALNT6 for paralogs About GeneDecksing
|
Genomic Variants for GALNT6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 12 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for GALNT6 (51745682 - 51785200 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for GALNT6: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GALNT6 |
|
Disorders
/ Diseases for GALNT6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GALNT6 for disorders About GeneDecksing
OMIM gene information: 605148
OMIM disorders: --
5 diseases for GALNT6: About MalaCardscicatricial pemphigoid breast cancer thyroiditis prostatitis carcinoma Human Genome Epidemiology (HuGE) Navigator: GALNT6 (1 document) Export disorders for GALNT6 gene to outside databases
|
Publications for GALNT6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GALNT6 gene, integrated from 9 sources (see all 15): (articles sorted by number of sources associating them with GALNT6) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and characterization of a close homologue of human UDP-N- acetyl--D-galactosamine:polypeptide N-acetylgalactosaminyltransferase- T3, designated GalNAc-T6. Evidence for genetic but not functional redundancy. (PubMed id 10464263)1, 2, 3 Bennett E.P.... Clausen H. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Expression of UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-6 in gastric mucosa, intestinal metaplasia, and gastric carcinoma. (PubMed id 18854599)1, 9 Gomes J....Reis C.A. (2009)
- Prognostic utility of glycosyltransferase expression in breast cancer. (PubMed id 19287074)1, 9 Patani N....Mokbel K. (2008)
- Polypeptide N-acetylgalactosaminyltransferase 6 disru pts mammary acinar morphogenesis through O-glycosylation of fibronectin. (PubMed id 21472136)1 Park J.H....Nakamura Y. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (2005)
- The cell-layer- and cell-type-specific distribution of GalNAc-transferases in the ocular surface epithelia is altered during keratinization. (PubMed id 12506059)1 Argueso P....Gipson I.K. (2003)
|
External Searches for GALNT6 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing GALNT6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing GALNT6 gene
(According to HUGE)
About This Section
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Specialized Databases showing GALNT6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
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| Name | Description |
| PharmGKB entry for GALNT6 | Pharmacogenomics, SNPs, Pathways | | GGDB | http://riodb.ibase.aist.go.jp/rcmg/ggdb/ | | Functional Glycomics Gateway - GTase | http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_488 |
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About This Section
| Patent Information for GALNT6 gene: Search GeneIP for patents involving GALNT6
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for GALNT6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for GALNT6 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GALNT6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GALNT6 | | OriGene Protein Over-expression Lysate for GALNT6 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for GALNT6 | | OriGene 3'-UTR Clone for GALNT6 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GALNT6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GALNT6 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for GALNT6 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for GALNT6 | | OriGene Custom Protein Services for GALNT6 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GALNT6 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GALNT6 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GALNT6 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GALNT6 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GALNT6 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GALNT6 |
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| | | Search Tocris compounds for GALNT6 |
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 | | GALNT6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GALNT6 |
|  |  |  | | | Search ThermoFisher Antibodies for GALNT6 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GALNT6 |
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