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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GALNT5 Gene

protein-coding   GIFtS: 57
GCID: GC02P158079

UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide
N-Acetylgalactosaminyltransferase 5 (GalNAc-T5)1 2
     EC 2.4.1.413 8
Polypeptide GalNAc Transferase 52 3     GALNAC-T52
Protein-UDP Acetylgalactosaminyltransferase 52 3     GALNACT52
Pp-GaNTase 52 3     Polypeptide N-Acetylgalactosaminyltransferase 52
UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 52 3     GalNAc-T53

External Ids:    HGNC: 41271   Entrez Gene: 112272   Ensembl: ENSG000001365427   OMIM: 6151295   UniProtKB: Q7Z7M93   

Export aliases for GALNT5 gene to outside databases

Previous GC identifers: GC02P156046 GC02P156644 GC02P158316 GC02P157939 GC02P157822 GC02P149999


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for GALNT5 Gene: 
GALNT5 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)) is a protein-coding gene. Diseases associated with GALNT5 include hereditary multiple exostoses, and exostosis, and among its related super-pathways are Mucin type O-Glycan biosynthesis and Post-translational protein modification. GO annotations related to this gene include polypeptide N-acetylgalactosaminyltransferase activity. An important paralog of this gene is GALNT6.

UniProtKB/Swiss-Prot: GALT5_HUMAN, Q7Z7M9
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward
EA2 peptide substrate, but has a weak activity toward Muc2 or Muc1b substrates (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GALNT5 gene promoter:
         Max1   HOXA9   HOXA9B   FOXO3   FOXO3b   Meis-1b   MEF-2A   FOXO3a   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGALNT5 promoter sequence
   Search SABiosciences Chromatin IP Primers for GALNT5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GALNT5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.1   Ensembl cytogenetic band:  2q24.1   HGNC cytogenetic band: 2q24.1

GALNT5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GALNT5 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P158079:  view genomic region     (about GC identifiers)

Start:
158,114,110 bp from pter      End:
158,170,723 bp from pter
Size:
56,614 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GALT5_HUMAN, Q7Z7M9 (See protein sequence)
Recommended Name: Polypeptide N-acetylgalactosaminyltransferase 5  
Size: 940 amino acids; 106266 Da
Cofactor: Manganese (By similarity)
Cofactor: Calcium (By similarity)
Subunit: Interacts with EXT2. Does not interact with EXT1, EXTL1 or EXTL3
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)
Secondary accessions: A5PKZ1 Q9UGK7 Q9UHL6

Explore the universe of human proteins at neXtProt for GALNT5: NX_Q7Z7M9

Explore proteomics data for GALNT5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z7M9

  • 4/9 DME Specific Peptides for GALNT5 (Q7Z7M9) (see all 9)
     GLIRARL  LGTYDPG  PCSRVGH  GWLEPLL 

    GALNT5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GALNT5 Protein Expression
    REFSEQ proteins: NP_055383.1  
    ENSEMBL proteins: 
     ENSP00000259056  
    Reactome Protein details: Q7Z7M9
    Human Recombinant Protein Products for GALNT5: 
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    Browse Sino Biological Recombinant Proteins
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    Cloud-Clone Corp. Proteins for GALNT5 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005575cellular_component ND--
    GO:0016021integral to membrane IEA--

    GALNT5 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for GALNT5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GLT2: Glycosyltransferase family 2 domain containing

    2 InterPro protein domains:
     IPR000772 Ricin_B_lectin
     IPR001173 Glyco_trans_2

    Graphical View of Domain Structure for InterPro Entry Q7Z7M9

    ProtoNet protein and cluster: Q7Z7M9

    2 Blocks protein domains:
    IPB000772 Ricin B lectin domain
    IPB001173 Glycosyl transferase


    UniProtKB/Swiss-Prot: GALT5_HUMAN, Q7Z7M9
    Domain: There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also
    called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal
    domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal
    binding (By similarity)
    Domain: The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity (By
    similarity)
    Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily
    Similarity: Contains 1 ricin B-type lectin domain


    GALNT5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GALT5_HUMAN, Q7Z7M9
    Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
    N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward
    EA2 peptide substrate, but has a weak activity toward Muc2 or Muc1b substrates (By similarity)
    Catalytic activity: UDP-N-acetyl-alpha-D-galactosamine + polypeptide = UDP +
    N-acetyl-alpha-D-galactosaminyl-polypeptide

         Enzyme Number (IUBMB): EC 2.4.1.411 2

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004653polypeptide N-acetylgalactosaminyltransferase activity IDA10545594
         
    GALNT5 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for GALNT5:
     Cell division defect  Increased G1 DNA content 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Galnt5):
     normal 

    GALNT5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Galnt5tm1Tabk for GALNT5

       inGenious Targeting Laboratory - Custom generated mouse model solutions for GALNT5 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GALNT5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GALNT5 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GALNT5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.44
    Mucin type O-Glycan biosynthesis0.44
    2Asparagine N-linked glycosylation
    Post-translational protein modification0.44
    Metabolism of proteins0.35
    3Metabolism
    Metabolic pathways0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for GALNT5
        O-linked glycosylation of mucins
    Metabolism of proteins
    Post-translational protein modification


    2         Kegg Pathways  (Kegg details for GALNT5):
        Mucin type O-Glycan biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: GALT5_HUMAN, Q7Z7M9
    Pathway: Protein modification; protein glycosylation


    GALNT5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GALNT5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/37 Interacting proteins for GALNT5 (Q7Z7M93 ENSP000002590564) via UniProtKB, MINT, STRING, and/or I2D (see all 37)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXT2Q930633, ENSP000003426564I2D: score=1 STRING: ENSP00000342656
    C1GALT1ENSP000002231224STRING: ENSP00000223122
    GALNT1ENSP000002691954STRING: ENSP00000269195
    GALNT10ENSP000002971074STRING: ENSP00000297107
    GALNT11ENSP000003158354STRING: ENSP00000315835
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006024glycosaminoglycan biosynthetic process TAS10545594
    GO:0016266O-glycan processing TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    GALNT5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GALNT5 (GALT5)

    5 HMDB Compounds for GALNT5    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Lactosaminebeta-D-galactopyranosyl-(1->4)-2-amino-2-deoxy-D-glucose (see all 8)13000-25-4--
    Manganesemanganese 7439-96-5--
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate-N-acetylgalactosamineUDP-N-acetyl-D-galactosamine (see all 17)7277-98-7--

    Search CenterWatch for drugs/clinical trials and news about GALNT5 / GALT5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GALNT5 gene: 
    NM_014568.1  

    Unigene Cluster for GALNT5:

    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
    Hs.269027  [show with all ESTs]
    Unigene Representative Sequence: BC142703
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000259056(uc002tzg.3 uc010zci.2) ENST00000463418 ENST00000461704

    miRNA
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    Additional mRNA sequence: 

    AF154107.1 AJ245539.1 AJ505956.1 AK292154.1 AY277591.1 BC142676.1 BC142703.1 BC144211.1 

    7 DOTS entries:

    DT.108869  DT.105956  DT.120956420  DT.208653  DT.91790977  DT.91986228  DT.99977002 

    24/80 AceView cDNA sequences (see all 80):

    AU121513 BQ001541 BM756024 BX092707 NM_014568 BM772900 BX487858 BQ009578 
    T35625 AY277591 BM738342 CA445475 BM828574 AJ245539 BX487859 CB159930 
    W92702 BM772895 AI025654 AI017189 AA704077 BM827362 AK022198 AI075794 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GALNT5 expression in normal human tissues (normalized intensities)      GALNT5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGACCACCT
    GALNT5 Expression
    About this image


    GALNT5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 8 entries
             Thalamus
             Olfactory Bulb   
     
     Mesenchymal Stem Cells
             Human Mesenchymal Stem Cells (hMSC)-1   
     
     Colon (Gastrointestinal Tract)
             sigmoid colon mucosa   
     
     Epidermis (Integumentary System)
             Detroit 551
     
     Bone (Muscoskeletal System)
             Human Vertebral Mesenchymal Stem Cells (HVMSC)   

    See GALNT5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GALNT5

    SOURCE GeneReport for Unigene cluster: Hs.269027
        SABiosciences Expression via Pathway-Focused PCR Arrays including GALNT5: 
              Glycosylation in human mouse rat
              Necrosis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Cell Death PathwayFinder in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GALNT5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GALNT5 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Galnt51 , 5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase more1, 5 81.27(n)1
    75.24(a)1
      2 (32.93 cM)5
    2413911  NM_172855.31  NP_766443.21 
     579978845 
    chicken
    (Gallus gallus)
    Aves GALNT51 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase more 68.44(n)
    70.21(a)
      424324  XM_422169.3  XP_422169.3 
    lizard
    (Anolis carolinensis)
    Reptilia GALNT56
    Uncharacterized protein
    51(a)
    1 ↔ 1
    GL343254.1(473391-530258)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003347841 polypeptide N-acetylgalactosaminyltransferase 5-like 64.68(n)
    66.67(a)
      100334784  XM_002667221.2  XP_002667267.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG21033 polypeptide
    N-acetylgalactosaminyltransferase
    38(a)
    (best of 5)
      62F4   --
    worm
    (Caenorhabditis elegans)
    Secernentea Y47D3A.233   -- 47(a)
    (best of 4)
      III(11351401-11357765)   --


    ENSEMBL Gene Tree for GALNT5 (if available)
    TreeFam Gene Tree for GALNT5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GALNT5 gene
    GALNT62  POC1B-GALNT42  GALNT122  GALNT72  GALNT12  GALNTL62  GALNT142  GALNTL52  
    GALNT32  GALNT22  GALNT102  GALNT42  GALNT132  GALNT162  GALNT112  
    14 SIMAP similar genes for GALNT5 using alignment to 3 protein entries:     GALT5_HUMAN (see all proteins):
    GALNT13    GALNT1    GALNT6    GALNT10    GALNT19    GALNT4
    GALNT8    WBSCR17    GALNT2    GALNT3    GALNT11    GALNT15
    GALNTL6    GALNT7

    GALNT5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1256 SNPs in GALNT5 are shown (see all 1256)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0359914
    A breast cancer sample4--see VAR_0359912 E D mis40--------
    VAR_0359924
    A breast cancer sample4--see VAR_0359922 L F mis40--------
    rs1812364251,2
    --158112342(+) GGGAAA/GGAATG 1 -- us2k10--------
    rs1156392941,2
    F--158112429(+) TGAGTT/CGCAGT 1 -- us2k11Minor allele frequency- C:0.02NA 120
    rs750137741,2
    C,F--158112478(+) GAAACC/TTCAGT 1 -- us2k11Minor allele frequency- T:0.03EA 120
    rs1161556001,2
    F--158112511(+) AACCAG/AGAAAG 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1849424411,2
    C--158112809(+) AGGGCA/TTCTCC 1 -- us2k10--------
    rs21975851,2
    C,F,A--158112900(-) cccagA/Ggaacc 1 -- us2k14Minor allele frequency- G:0.27WA CSA NA 242
    rs21975841,2
    H--158112947(-) TATGAG/AACATt 1 -- us2k1 tfbs34Minor allele frequency- A:0.00NS EA 416
    rs1898108571,2
    --158112955(+) ATAGGC/TAATGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GALNT5 (158114110 - 158170723 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for GALNT5:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2661479CNV Deletion23128226
    nsv875328CNV Loss21882294
    nsv834432CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 615129    OMIM disorders: --

    2 diseases for GALNT5:    About MalaCards
    hereditary multiple exostoses    exostosis

    1 disease from the University of Copenhagen DISEASES database for GALNT5:
    Exostosis

    GALNT5 for disorders           About GeneDecksing


    Export disorders for GALNT5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GALNT5 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with GALNT5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses. (PubMed id 10545594)1, 2, 3 Simmons A.D....Lovett M. (1999)
    2. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    3. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    4. The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. (PubMed id 17203973)1 Vasilescu J.... Figeys D. (2007)
    5. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11227 HGNC: 4127 AceView: GALNT5 Ensembl:ENSG00000136542 euGenes: HUgn11227
    ECgene: GALNT5 Kegg: 11227 H-InvDB: GALNT5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GALNT5 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_487

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GALNT5 gene:
    Search GeneIP for patents involving GALNT5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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