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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GALNT4 Gene

protein-coding   GIFtS: 50
GCID: GC12M089913

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase...
 Explore 2 diseases affiliated with
GALNT4 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for GALNT4    

Aliases
for GALNT4 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide
N-Acetylgalactosaminyltransferase 4 (GalNAc-T4)1 2
     EC 2.4.1.413 8
GalNAc-T41 3     GALNAC-T42
Polypeptide GalNAc Transferase 42 3     GALNACT42
Protein-UDP Acetylgalactosaminyltransferase 42 3     Polypeptide N-Acetylgalactosaminyltransferase 42
Pp-GaNTase 42 3     GalNAcT45
UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 42 3     

External Ids:    HGNC: 41261   Entrez Gene: 86932   Ensembl: ENSG000002575947   OMIM: 6035655   UniProtKB: Q8N4A03   

Export aliases for GALNT4 gene to outside databases

Previous GC identifers: GC12M089334 GC12M090360 GC12M089849 GC12M088419 GC12M088415


Summaries
for GALNT4 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for GALNT4:
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase
(GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by
catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an
N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc
transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate
specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete
O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The
coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with
the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist. (provided by RefSeq, Dec
2010)

UniProtKB/Swiss-Prot: GALT4_HUMAN, Q8N4A0
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity
toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates 'Thr-57' of SELPLG




Genomic Views
for GALNT4 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
 Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GALNT4 gene promoter:
         Nkx3-1   Nkx3-1 v4   NRSF form 1   Nkx3-1 v1   CUTL1   NRSF form 2   Nkx3-1 v2   POU2F1   POU2F1a   Nkx3-1 v3   
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GALNT4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21.33   Ensembl cytogenetic band:  12q21.33   HGNC cytogenetic band: 12q21.33

GALNT4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GALNT4 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M089913:  view genomic region     (about GC identifiers)

Start:
 89,913,185 bp from pter      End:
 89,918,583 bp from pter
Size:
 5,399 bases      Orientation:
 minus strand

Proteins
for GALNT4 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: GALT4_HUMAN, Q8N4A0 (See protein sequence)
Recommended Name: Polypeptide N-acetylgalactosaminyltransferase 4  
Size: 578 amino acids; 66666 Da
Cofactor: Manganese (By similarity)
Cofactor: Calcium (By similarity)
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (Probable)
Secondary accessions: B2R775 B4DMX6 O00208
Alternative splicing: 2 isoforms:  Q8N4A0-1   Q8N4A0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GALNT4: NX_Q8N4A0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8N4A0

    • 4/9 DME Specific Peptides for GALNT4 (Q8N4A0) (see all 9)
     VVCPVID  MAGGLFA  PTMAGGL  WGGENLE 

    GALNT4 Protein expression data from MOPED and PaxDb:    About this image 
    GALNT4 Protein Expression
    REFSEQ proteins: NP_003765.2  
    ENSEMBL proteins: 
     ENSP00000436604  
    Reactome Protein details: Q8N4A0
    Human Recombinant Protein Products for GALNT4: 
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    Novus Biologicals GALNT4 Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for GALNT4

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005794colocalizes with Golgi apparatus IDA12506059
    GO:0016021integral to membrane IEA--
    GO:0048471perinuclear region of cytoplasm IDA12506059

    GALNT4 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for GALNT4

    Protein Domains /
    Families
    for GALNT4 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    GALNT4 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000772 Ricin_B_lectin
     IPR001173 Glyco_trans_2

    Graphical View of Domain Structure for InterPro Entry Q8N4A0

    ProtoNet protein and cluster: Q8N4A0

    2 Blocks protein families:
    IPB000772 Ricin B lectin domain
    IPB001173 Glycosyl transferase


    UniProtKB/Swiss-Prot: GALT4_HUMAN, Q8N4A0
    Domain: There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called
    GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain
    (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding (By
    similarity)
    Domain: The ricin B-type lectin domain directs the glycopeptide specificity. It is required in the glycopeptide
    specificity of enzyme activity but not for activity with naked peptide substrates, suggesting that it triggers the
    catalytic domain to act on GalNAc-glycopeptide substrates
    Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily
    Similarity: Contains 1 ricin B-type lectin domain


    Function
    for GALNT4 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GALT4_HUMAN, Q8N4A0
    Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
    N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity
    toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates 'Thr-57' of SELPLG
    Catalytic activity: UDP-N-acetyl-alpha-D-galactosamine + polypeptide = UDP +
    N-acetyl-alpha-D-galactosaminyl-polypeptide

         Genatlas biochemistry entry for GALNT4:
    galactosamine

         Enzyme Number (IUBMB): EC 2.4.1.411 2

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004653polypeptide N-acetylgalactosaminyltransferase activity IEA--
    GO:0030246carbohydrate binding ----
         
    GALNT4 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Galnt4):
     normal 

    GALNT4 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Galnt4tm1Tabk for GALNT4
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for GALNT4 

    miRNA
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    hsa-miR-4328 hsa-let-7d hsa-miR-106a hsa-miR-218 hsa-miR-519a hsa-miR-877* hsa-let-7g hsa-miR-3142
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for GALNT4 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein
    		O-linked glycosylation of mucins0.28
    		Mucin type O-Glycan biosynthesis0.00
    2Asparagine N-linked glycosylation
    		Post-translational protein modification0.44
    		Metabolism of proteins0.15
    3Metabolism
    		Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for GALNT4
        O-linked glycosylation of mucins
    Metabolism of proteins
    Post-translational protein modification


    2         Kegg Pathways  (Kegg details for GALNT4):
        Mucin type O-Glycan biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: GALT4_HUMAN, Q8N4A0
    Pathway: Protein modification; protein glycosylation


    GALNT4 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GALNT4

    1 Interacting protein for GALNT4 (Q8N4A03) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    MUC1P159413I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process NAS9592121
    GO:0016266O-glycan processing TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    GALNT4 for ontologies           About GeneDecksing



    Drugs & Compounds
    for GALNT4 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for GALNT4

    5 HMDB Compounds for GALNT4    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Lactosaminebeta-D-galactopyranosyl-(1->4)-2-amino-2-deoxy-D-glucose (see all 8)13000-25-4--
    Manganesemanganese 7439-96-5--
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate-N-acetylgalactosamineUDP-N-acetyl-D-galactosamine (see all 17)7277-98-7--
    Search CenterWatch for drugs/clinical trials and news about GALNT4 / GALT4 

    Transcripts
    for GALNT4 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for GALNT4 gene: 
    NM_003774.4  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000529983(uc001tbd.3)

    miRNA
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    8/51 QIAGEN miScript miRNA Assays for microRNAs that regulate GALNT4 (see all 51):
    hsa-miR-4328 hsa-let-7d hsa-miR-106a hsa-miR-218 hsa-miR-519a hsa-miR-877* hsa-let-7g hsa-miR-3142
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    Inhib. RNA
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    Clone
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    24/161 AceView cDNA sequences (see all 161):

    CN484379 BX282160 BM795268 AL708583 BM982932 BC036390 BM015484 BI768034 
    CR594597 CA441661 AI569994 NM_003774 BG182194 BQ000466 AK123625 BX281240 
    AL832918 BC026080 AW131361 AI444809 AI866908 CB851639 AL559656 AW874276 

    GeneLoc Exon Structure


    Expression
    for GALNT4 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GALNT4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --
    GALNT4 Expression
    About this image

    GALNT4 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LiverLiver LobulePerivenous HepatocytesLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See GALNT4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GALNT4

    UniProtKB/Swiss-Prot: GALT4_HUMAN, Q8N4A0
    Tissue specificity: Ubiquitous. Highly expressed in mucous cells

        SABiosciences Expression via Pathway-Focused PCR Arrays including GALNT4: 
              Glycosylation in human mouse rat
              Drug Metabolism: Phase II Enzymes in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for GALNT4 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for GALNT4 gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves WDR51B6
    		 WD repeat domain 51B
    		 77(a)
    		 1 → many
    		 1(45210136-45254094)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 75(a)
    		 1 → many
    		 GL343332.1(1361662-1363413)
    zebrafish
    (Danio rerio)    		 Actinopterygii poc1bl1 POC1 centriolar protein homolog B (Chlamydomonas), more 67.65(n)
    72.13(a)    		   503760  NM_001044778.2  NP_001038243.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta GalNAc-T13 polypeptide
    N-acetylgalactosaminyltransferase    		 39(a)
    (best of 5)    		   52A6   --
    worm
    (Caenorhabditis elegans)    		 Secernentea Y39E4B.12a3   -- 47(a)
    (best of 5)    		   III(13259420-13275737)   --


    ENSEMBL Gene Tree for GALNT4 (if available)
    TreeFam Gene Tree for GALNT4 (if available) 

    Paralogs
    for GALNT4 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GALNT4 gene
    GALNT62  POC1B-GALNT42  GALNT122  GALNT52  GALNT72  GALNT12  GALNTL62  GALNT142  
    GALNTL52  GALNT32  GALNT22  GALNT102  GALNT132  GALNT162  GALNT112  
    18/25 SIMAP similar genes for GALNT4 using alignment to 2 protein entries:     GALT4_HUMAN (see all proteins) (see all similar genes):
    POC1B-GALNT4    GALNT12    GalNAc-T10    GALNT13    GALNT1    GALNT6
    GALNT3    GALNTL5    GALNTL6    GalNAc-T16    GALNT10    GALNT11
    GALNT14    GALNT15    GALNT5    GALNT2    GALNTL2    GALNT16

    GALNT4 for paralogs           About GeneDecksing



    Genomic Variants
    for GALNT4 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/82 NCBI SNPs in GALNT4 are shown (see all 82)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1417542781,2
    		--89912816(+) ATTTAC/TGGACC 7 -- ds5001 int10--------
    rs758918011,2
    		C,F--89912821(+) TGGACC/TGGGGA 7 -- int1 ds50013Minor allele frequency- T:0.05WA CSA 122
    rs1817832071,2
    		--89912889(+) AAATTC/GGTGCT 7 -- int1 ds50010--------
    rs108588921,2
    		C,F,A,H--89912955(+) ATCCCT/AGATCA 7 -- ds5001 int120Minor allele frequency- A:0.24NS EA NA WA CSA 1156
    rs1864406761,2
    		--89913036(+) TGACAC/TGTTGT 7 -- int1 ds50010--------
    rs1881662111,2
    		--89913039(+) CACGTC/TGTAAA 7 -- int1 ds50010--------
    rs1809246411,2
    		--89913192(+) TATTTA/GCAAAA 7 -- ut31 int10--------
    rs108588931,2
    		C,F,A,H--89913323(+) TCAACA/GTTCTT 7 -- int1 ut3120Minor allele frequency- G:0.27NA EA WA CSA 868
    rs1860983751,2
    		--89913353(+) TTAAAA/TCAGGA 7 -- int1 ut310--------
    rs10548071,2
    		C,F,H--89913419(-) AGTTGG/ATTTAG 7 -- ut31 int115Minor allele frequency- A:0.16NS EA NA WA 2142

    HapMap Linkage Disequilibrium report for GALNT4 (89913185 - 89918583 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for GALNT4: --

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GALNT4
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    Disorders / Diseases
    for GALNT4 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    GALNT4 for disorders           About GeneDecksing

    OMIM gene information: 603565    OMIM disorders: --

    2 diseases for GALNT4:    About MalaCards
    breast cancer    carcinoma

    Human Genome Epidemiology (HuGE) Navigator: GALNT4 (1 document)

    Export disorders for GALNT4 gene to outside databases

    Publications
    for GALNT4 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GALNT4 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with GALNT4)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N- acetylgalactosaminyltransferase that complements other GalNAc- transferases in complete O-glycosylation of the MUC1 tandem repeat. (PubMed id 9804815)1, 2, 3 Bennett E.P.... Clausen H. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The lectin domain of UDP-N-acetyl-D-galactosamine: polypeptide N- acetylgalactosaminyltransferase-T4 directs its glycopeptide specificities. (PubMed id 10984485)1, 2 Hassan H.... Clausen H. (2000)
    4. Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2). (PubMed id 18259693)1, 9 O'Halloran A.M....Shields D.C. (2008)
    5. Estrogen regulates vesicle trafficking gene expressio n in EFF-3, EFM-19 and MCF-7 breast cancer cells. (PubMed id 19294005)1 Wright P.K....Westley B.R. (2009)
    6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    7. Differential gene expression profiles of normal human parotid and submandibular glands. (PubMed id 18826381)1 Sun Q.F....Wang S. (2008)
    8. The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc- glycopeptide substrates is required for high density GalNAc-O-glycosylation. (PubMed id 17215257)1 Wandall H.H....Clausen H. (2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)

    External Searches for GALNT4 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing GALNT4 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8693 HGNC: 4126 AceView: GALNT4 Ensembl:ENSG00000257594 euGenes: HUgn8693
    ECgene: GALNT4 Kegg: 8693 H-InvDB: GALNT4

    Other Databases showing GALNT4 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing GALNT4 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GALNT4 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_486

    Intellectual Property
    for GALNT4 gene

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    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for GALNT4 gene:
    Search GeneIP for patents involving GALNT4

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