Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



GALNT16 Gene

protein-coding   GIFtS: 49
GCID: GC14P069725

Polypeptide N-Acetylgalactosaminyltransferase 16

(Previous names: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like...)
(Previous symbol: GALNTL1)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Polypeptide N-Acetylgalactosaminyltransferase 161 2     Protein-UDP Acetylgalactosaminyltransferase-Like Protein 12 3
GALNTL11 2 3 5     GalNAc-T162 3
Polypeptide GalNAc Transferase 161 2 3     Pp-GaNTase-Like Protein 12 3
UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide
N-Acetylgalactosaminyltransferase 161 2
     UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase-Like Protein 12 3
UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide
N-Acetylgalactosaminyltransferase-Like 11 2
     GALNACT162 5
GalNAc-T-Like Protein 12 3     KIAA11303 5
Polypeptide GalNAc Transferase-Like Protein 12 3     Putative Polypeptide N-Acetylgalactosaminyltransferase-Like Protein 12
Polypeptide N-Acetylgalactosaminyltransferase-Like Protein 12 3     EC 2.4.1.413

External Ids:    HGNC: 232331   Entrez Gene: 574522   Ensembl: ENSG000001006267   OMIM: 6151325   UniProtKB: Q8N4283   

Export aliases for GALNT16 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for GALNT16 Gene:
GALNT16 (polypeptide N-acetylgalactosaminyltransferase 16) is a protein-coding gene. GO annotations related to this gene include polypeptide N-acetylgalactosaminyltransferase activity. An important paralog of this gene is GALNT12.

UniProtKB/Swiss-Prot: GLT16_HUMAN, Q8N428
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Search for regulatory transcription factor binding sites for GALNT16
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGALNT16 promoter sequence
   Search Chromatin IP Primers for GALNT16

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GALNT16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24.1   Ensembl cytogenetic band:  14q24.1   HGNC cytogenetic band: 14q24.1

GALNT16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GALNT16 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P069725:  view genomic region     (about GC identifiers)

Start:
69,725,994 bp from pter      End:
69,821,190 bp from pter
Size:
95,197 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: GLT16_HUMAN, Q8N428 (See protein sequence)
Recommended Name: Polypeptide N-acetylgalactosaminyltransferase 16  
Size: 558 amino acids; 63074 Da
Cofactor: Manganese (By similarity)
Sequence caution: Sequence=BAA86444.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q4KMG3 Q9ULT9
Alternative splicing: 2 isoforms:  Q8N428-1   Q8N428-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GALNT16: NX_Q8N428

Explore proteomics data for GALNT16 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Thr55, Thr61, Thr63
  • Modification sites at PhosphoSitePlus

  • See GALNT16 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001161840.1  NP_065743.2  

    ENSEMBL proteins: 
     ENSP00000336729   ENSP00000451420   ENSP00000402970   ENSP00000451200  
    Reactome Protein details: Q8N428

    GALNT16 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for GALNT16 (GALNTL1)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for GALNT16
    OriGene Custom MassSpec
    OriGene Custom Protein Services for GALNT16
    GenScript Custom Purified and Recombinant Proteins Services for GALNT16
    Novus Biologicals GALNT16 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for GALNT16 

    GALNT16 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for GALNT16
    Novus Biologicals GALNT16 Antibodies
    Search for Antibodies for GALNT16 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibody for GALNT16
    LSBio Antibodies in human, mouse, rat for GALNT16

    GALNT16 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for GALNT16
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for GALNT16
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for GALNT16 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    GLT2: Glycosyltransferase family 2 domain containing

    3 InterPro protein domains:
     IPR000772 Ricin_B_lectin
     IPR001173 Glyco_trans_2
     IPR027791 Galactosyl_T_C

    Graphical View of Domain Structure for InterPro Entry Q8N428

    ProtoNet protein and cluster: Q8N428

    2 Blocks protein domains:
    IPB000772 Ricin B lectin domain
    IPB001173 Glycosyl transferase


    UniProtKB/Swiss-Prot: GLT16_HUMAN, Q8N428
    Domain: There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also
    called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal
    domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal
    binding (By similarity)
    Domain: The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity (By
    similarity)
    Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily
    Similarity: Contains 1 ricin B-type lectin domain


    Find genes that share domains with GALNT16           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GLT16_HUMAN, Q8N428
    Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
    N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor
    Catalytic activity: UDP-N-acetyl-alpha-D-galactosamine + polypeptide = UDP +
    N-acetyl-alpha-D-galactosaminyl-polypeptide
    Biophysicochemical properties: Kinetic parameters: KM=251 uM for Muc5AC; KM=310 uM for Muc5AC-3; KM=390 uM for
    Muc5AC-13; KM=332 uM for EA2;

         Enzyme Number (IUBMB): EC 2.4.1.411

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004653polypeptide N-acetylgalactosaminyltransferase activity IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with GALNT16           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Galnt16 (no phenotypes)

    Find genes that share phenotypes with GALNT16           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GALNT16
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for GALNT16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GALNT16
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GALNT16

    miRNA
    Products:
        
    miRTarBase miRNAs that target GALNT16:
    hsa-mir-335-5p (MIRT016819)

    Block miRNA regulation of human, mouse, rat GALNT16 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate GALNT16
    SwitchGear 3'UTR luciferase reporter plasmidGALNT16 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for GALNT16
    Predesigned siRNA for gene silencing in human, mouse, rat GALNT16

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for GALNT16

    Clone
    Products:
         
    OriGene clones in human, mouse for GALNT16 (see all 9)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for GALNT16
    Sino Biological Human cDNA Clone for GALNT16
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GALNT16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GALNT16

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for GALNT16
    Browse ESI BIO Cell Lines and PureStem Progenitors for GALNT16 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GALNT16


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    GLT16_HUMAN, Q8N428: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with GALNT16           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for GALNT16 About    
    See pathways by source

    SuperPathContained pathways About
    1O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.47
    Mucin type O-Glycan biosynthesis0.47
    2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Post-translational protein modification0.43
    Metabolism of proteins0.30
    3Metabolism
    Metabolic pathways0.38


    Find genes that share SuperPaths with GALNT16           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for GALNT16
        O-linked glycosylation of mucins


    2 Kegg Pathways  (Kegg details for GALNT16):
        Mucin type O-Glycan biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: GLT16_HUMAN, Q8N428
    Pathway: Protein modification; protein glycosylation

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GALNT16
    Interactions:

        Search GeneGlobe Interaction Network for GALNT16

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for GALNT16 (ENSP000003367294) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ST6GALNAC1ENSP000001566264STRING: ENSP00000156626
    B3GNT6ENSP000003462564STRING: ENSP00000346256
    C1GALT1ENSP000002231224STRING: ENSP00000223122
    C1GALT1C1ENSP000003043644STRING: ENSP00000304364
    GCNT1ENSP000003659204STRING: ENSP00000365920
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation IEA--

    Find genes that share ontologies with GALNT16           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GALNT16 (GLT16)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for GALNT16 gene (2 alternative transcripts): 
    NM_001168368.1  NM_020692.2  

    Unigene Cluster for GALNT16:

    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
    Hs.21035  [show with all ESTs]
    Unigene Representative Sequence: NM_001168368
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000554858 ENST00000554317 ENST00000555920 ENST00000337827(uc001xlb.2 uc010aqu.2)
    ENST00000553471(uc001xla.2) ENST00000448469 ENST00000553669 ENST00000553740
    ENST00000556677 ENST00000556829
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat GALNT16 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate GALNT16
    SwitchGear 3'UTR luciferase reporter plasmidGALNT16 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for GALNT16
    Predesigned siRNA for gene silencing in human, mouse, rat GALNT16
    Clone
    Products:
         
    OriGene clones in human, mouse for GALNT16 (see all 9)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for GALNT16
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GALNT16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GALNT16
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for GALNT16
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat GALNT16
      QuantiTect SYBR Green Assays in human, mouse, rat GALNT16
      QuantiFast Probe-based Assays in human, mouse, rat GALNT16

    Additional mRNA sequence: 

    AB078143.1 AJ505951.1 AK091426.1 AK289745.1 AK299588.1 AK315848.1 BC036812.1 BC098578.1 
    BC122545.1 

    6 DOTS entries:

    DT.97810619  DT.75182256  DT.211280  DT.120732218  DT.427445  DT.91810121 

    Selected AceView cDNA sequences (see all 39):

    AX746976 BC036812 AK091426 BQ889087 AB032956 AJ505951 C04825 BM713273 
    BG152513 BM547713 AI825621 BM548291 BI823973 AW268864 AW960794 AI097463 
    BG059801 CD672463 AA337647 CD672462 BE261736 BQ722096 AI750782 AI906421 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for GALNT16 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18
    SP1:                                -                                                                                                               
    SP2:                                                                                                                                                
    SP3:              -                 -                                                                                                               
    SP4:                                                                                                                                                
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for GALNT16

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    GALNT16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    GALNT16 Expression
    About this image


    GALNT16 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Thalamus
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Heart (Cardiovascular System)
             Atrioventricular Node Cells Atrioventricular Node
    GALNT16 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GALNT16 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.21035
        Custom PCR Arrays for GALNT16
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for GALNT16
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat GALNT16
    QuantiTect SYBR Green Assays in human, mouse, rat GALNT16
    QuantiFast Probe-based Assays in human, mouse, rat GALNT16
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GALNT16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for GALNT16 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Galnt161 , 5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like more5
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase more1
    90.26(n)1
    96.06(a)1
      12 (36.79 cM)5
    1087601  NM_001081421.11  NP_001074890.11 
     805189905 
    chicken
    (Gallus gallus)
    Aves GALNTL11 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like more 75.68(n)
    78.7(a)
      423263  XM_001231964.3  XP_001231965.2 
    lizard
    (Anolis carolinensis)
    Reptilia GALNT166
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-a...
    76(a)
    1 ↔ 1
    GL343318.1(124017-397504)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.89262 Xenopus laevis transcribed sequence with weak similarity more 77.39(n)    BG578174.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.223292 Transcribed sequence with weak similarity to protein more 73.34(n)    57078646 
    fruit fly
    (Drosophila melanogaster)
    Insecta pgant26
    polypeptide GalNAc transferase 2
    42(a)
    1 → many
    2L(3404460-3426642)
    worm
    (Caenorhabditis elegans)
    Secernentea gly-66
    Protein GLY-6, isoform c
    32(a)
    many ↔ many
    III(4324288-4331227) WBGene00001631


    ENSEMBL Gene Tree for GALNT16 (if available)
    TreeFam Gene Tree for GALNT16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for GALNT16 gene
    GALNT122  GALNT12  GALNTL62  GALNT32  GALNT22  GALNT102  GALNT132  GALNT62  
    POC1B-GALNT42  GALNT152  GALNT72  GALNT52  GALNT142  GALNTL52  GALNT42  GALNT112  
    Selected SIMAP similar genes for GALNT16 using alignment to 2 protein entries:     GLT16_HUMAN (see all proteins) (see all similar genes):
    GalNAc-T16    GALNT14    GALNT2    GALNTL6    GALNTL5    GALNT11
    GALNT1    GALNT10    GALNT3    GALNT13    GALNT12    GALNT7
    GalNAc-T10    GALNT9    GALNT6    GALNT4    POC1B-GALNT4    GALNT18

    Find genes that share paralogs with GALNT16           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for GALNT16 (see all 2182)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs340816691,2
    C--50754460(+) GTCTC-/A/AAA 
            
    AAAAA
    4 -- int1 cds10--------
    rs1437407341,2
    --69724735(+) ACAGGA/GCTACT 2 -- us2k10--------
    rs1468427161,2
    --69724747(+) CCCAAA/GTTTTC 2 -- us2k10--------
    rs1509708581,2
    C--69724838(+) CCTGT-/GGGAGC 2 -- us2k10--------
    rs1836338651,2
    --69724892(+) GCACCA/GCTGGA 2 -- us2k10--------
    rs1405661561,2
    C--69724981(+) CTGGCA/GCAGTC 2 -- us2k10--------
    rs767876041,2
    C,F--69725030(+) TCTGGC/TGTCTC 2 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1173771261,2
    F--69725285(+) AATGTA/GTTGAG 2 -- us2k11Minor allele frequency- G:0.01EA 120
    rs1883917041,2
    --69725300(+) TATTAC/TATGTG 2 -- us2k10--------
    rs1500417901,2
    --69725307(+) TGTGCA/GGTTCA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for GALNT16 (69725994 - 69821190 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for GALNT16: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GALNT16
    DNA2.0 Custom Variant and Variant Library Synthesis for GALNT16

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 615132    OMIM disorders: --


    Find genes that share disorders with GALNT16           About GenesLikeMe


    Export disorders for GALNT16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for GALNT16 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with GALNT16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. UDP-N-acetyl-I+-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. (PubMed id 22186971)1, 2, 3 Raman J....Tabak L.A. (Glycobiology 2012)
    2. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2, 3 Hirosawa M.... Ohara O. (DNA Res. 1999)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 57452 HGNC: 23233 AceView: GALNTL1 Ensembl:ENSG00000100626 euGenes: HUgn57452
    ECgene: GALNT16 Kegg: 57452 H-InvDB: GALNT16

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA1130

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for GALNT16 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=GALNT16
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_499

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for GALNT16 gene:
    Search GeneIP for patents involving GALNT16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Recombinant/Natural Proteins for GALNT16 (GALNTL1)   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for GALNT16  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for GALNT16  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for GALNT16  
     OriGene qSTAR qPCR primer pairs in human, mouse for GALNT16   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for GALNT16   OriGene Custom Protein Services for GALNT16  

     
     
     Block miRNA regulation of human, mouse, rat GALNT16 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing GALNT16
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GALNT16 Predesigned siRNA for gene silencing in human, mouse, rat GALNT16
     QuantiFast Probe-based Assays in human, mouse, rat GALNT16 QuantiTect SYBR Green Assays in human, mouse, rat GALNT16
     Custom PCR Arrays for GALNT16 Search Chromatin IP Primers for GALNT16
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat GALNT16 Search GeneGlobe Interaction Network for GALNT16
     Search Regulatory tfbs for GALNT16
     GenScript Custom Purified and Recombinant Proteins Services for GALNT16 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for GALNT16
     GenScript Custom Assay Services for GALNT16 GenScript Custom overexpressing Cell Line Services for GALNT16
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for GALNT16 (GLT16)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for GALNT16
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     GALNT16 antibodies
     GALNT16 lysates
     Search for Antibodies for GALNT16 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for GALNT16
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for GALNT16
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GALNT16
     SwitchGear 3'UTR luciferase reporter plasmids for GALNT16
     SwitchGear Promoter luciferase reporter plasmids for GALNT16
     ThermoFisher Antibody for GALNT16
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GALNT16
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GALNT16
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for GALNT16
     LSBio Antibodies in human, mouse, rat for GALNT16
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for GALNT16
      Search eBioscience for proteins for GALNT16
      Search eBioscience for elisas for GALNT16
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      GALNT16 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4