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GALNT15 Gene

protein-coding   GIFtS: 49
GCID: GC03P016216

Polypeptide N-Acetylgalactosaminyltransferase 15

(Previous names: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like...)
(Previous symbol: GALNTL2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Polypeptide N-Acetylgalactosaminyltransferase 151 2     GALNACT152 5
GALNTL21 2 3     GALNT132
UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide
N-Acetylgalactosaminyltransferase 151 2
     GALNT72
UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide
N-Acetylgalactosaminyltransferase-Like 21 2
     PIH52
Polypeptide GalNAc Transferase 151 2     Polypeptide N-Acetylgalactosaminyltransferase 132
GalNAc-T-Like Protein 22 3     pp-GalNAc-T152
Polypeptide GalNAc Transferase-Like Protein 22 3     Pregnancy-Induced Hypertension Syndrome-Related Protein 52
Polypeptide N-Acetylgalactosaminyltransferase-Like Protein 22 3     UDP-GalNAc Transferase T152
Protein-UDP Acetylgalactosaminyltransferase-Like Protein 22 3     UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide
N-Acetylgalactosaminyltransferase 72
Pp-GaNTase-Like Protein 22 3     EC 2.4.1.413
UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase-Like Protein 22 3     

External Ids:    HGNC: 215311   Entrez Gene: 1172482   Ensembl: ENSG000001313867   OMIM: 6151315   UniProtKB: Q8N3T13   

Export aliases for GALNT15 gene to outside databases

Previous GC identifers: GC07P150968 GC07P151045


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for GALNT15 Gene:
GALNT15 (polypeptide N-acetylgalactosaminyltransferase 15) is a protein-coding gene. Diseases associated with GALNT15 include hypertension, and schizophrenia. GO annotations related to this gene include polypeptide N-acetylgalactosaminyltransferase activity. An important paralog of this gene is GALNT6.

UniProtKB/Swiss-Prot: GLT15_HUMAN, Q8N3T1
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a
much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc
residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other
GALNT proteins. Prefers Muc1a as substrate

Gene Wiki entry for GALNT15 (GALNTL2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for GALNT15
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGALNT15 promoter sequence
   Search Chromatin IP Primers for GALNT15

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GALNT15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p25.1   Ensembl cytogenetic band:  3p25.1   HGNC cytogenetic band: 3p25.1

GALNT15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GALNT15 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P016216:  view genomic region     (about GC identifiers)

Start:
16,216,156 bp from pter      End:
16,273,499 bp from pter
Size:
57,344 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: GLT15_HUMAN, Q8N3T1 (See protein sequence)
Recommended Name: Polypeptide N-acetylgalactosaminyltransferase 15  
Size: 639 amino acids; 73063 Da
Cofactor: Manganese (By similarity)
Caution: Was originally (PubMed:15147861) termed Galnt15/pp-GaNTase 15
Sequence caution: Sequence=CAD89983.1; Type=Frameshift; Positions=169, 192, 206, 222, 270;
Secondary accessions: A6NMN1 B2R638 F1LIP6 Q86T60 Q96C46 Q96DJ5

Explore the universe of human proteins at neXtProt for GALNT15: NX_Q8N3T1

Explore proteomics data for GALNT15 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn107, Asn574

  • See GALNT15 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_473451.3  
    ENSEMBL proteins: 
     ENSP00000344260   ENSP00000395873   ENSP00000389079  
    Reactome Protein details: Q8N3T1

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    GLT2: Glycosyltransferase family 2 domain containing

    2 InterPro protein domains:
     IPR000772 Ricin_B_lectin
     IPR001173 Glyco_trans_2

    Graphical View of Domain Structure for InterPro Entry Q8N3T1

    ProtoNet protein and cluster: Q8N3T1

    2 Blocks protein domains:
    IPB000772 Ricin B lectin domain
    IPB001173 Glycosyl transferase


    UniProtKB/Swiss-Prot: GLT15_HUMAN, Q8N3T1
    Domain: There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also
    called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal
    domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal
    binding (By similarity)
    Domain: The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity (By
    similarity)
    Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily
    Similarity: Contains 1 ricin B-type lectin domain


    GALNT15 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GLT15_HUMAN, Q8N3T1
    Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
    N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a
    much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc
    residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other
    GALNT proteins. Prefers Muc1a as substrate
    Catalytic activity: UDP-N-acetyl-alpha-D-galactosamine + polypeptide = UDP +
    N-acetyl-alpha-D-galactosaminyl-polypeptide

         Enzyme Number (IUBMB): EC 2.4.1.411

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004653polypeptide N-acetylgalactosaminyltransferase activity IEA--
    GO:0016757transferase activity, transferring glycosyl groups ----
    GO:0046872metal ion binding IEA--
         
    GALNT15 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for GALNT15:
     Synthetic lethal with Ras 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GLT15_HUMAN, Q8N3T1: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005794Golgi apparatus ----
    GO:0016021integral component of membrane IEA--
    GO:0030133transport vesicle IDA--

    GALNT15 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for GALNT15 About    
    See pathways by source

    SuperPathContained pathways About
    1O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.47
    Mucin type O-Glycan biosynthesis0.47
    2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Post-translational protein modification0.43
    Metabolism of proteins0.30
    3Metabolism
    Metabolic pathways0.38

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for GALNT15
        O-linked glycosylation of mucins


    2 Kegg Pathways  (Kegg details for GALNT15):
        Mucin type O-Glycan biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: GLT15_HUMAN, Q8N3T1
    Pathway: Protein modification; protein glycosylation


    GALNT15 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GALNT15
    Interactions:

        Search GeneGlobe Interaction Network for GALNT15

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for GALNT15 (ENSP000003442604) via UniProtKB, MINT, STRING, and/or I2D (see all 37)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    B3GNT2ENSP000003055954STRING: ENSP00000305595
    B3GNT6ENSP000003462564STRING: ENSP00000346256
    GALNT1ENSP000002691954STRING: ENSP00000269195
    GALNT10ENSP000002971074STRING: ENSP00000297107
    GALNT11ENSP000003158354STRING: ENSP00000315835
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation ----
    GO:0016266O-glycan processing TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    GALNT15 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for GALNT15 (GLT15)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for GALNT15 gene: 
    NM_054110.4  

    Unigene Cluster for GALNT15:

    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
    Hs.411308  [show with all ESTs]
    Unigene Representative Sequence: AL832575
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000339732(uc003caq.4 uc003car.4 uc003cas.4) ENST00000437509
    ENST00000470031 ENST00000430410 ENST00000489467
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    Additional mRNA sequence: 

    AB078149.1 AF361251.1 AJ505964.1 AK094780.1 AK225673.1 AK312425.1 AL831925.1 AL832575.2 
    AL832736.1 AY035399.1 AY358443.1 BC014789.1 BC030625.1 

    13 DOTS entries:

    DT.91678870  DT.97777000  DT.99945053  DT.100026753  DT.99955970  DT.120921671  DT.120921628  DT.99947084 
    DT.100692345  DT.120921672  DT.40250977  DT.75181741  DT.99950832 

    Selected AceView cDNA sequences (see all 142):

    BX088662 AI160260 AI361083 BX105783 BQ005873 AA719759 AI148164 AW026164 
    BP343772 BE222916 BE855570 AB078149 AI039548 BQ005863 AI096576 AA625181 
    AW205686 N46627 BC014789 CA418641 BG054860 BX090886 N34901 BF366468 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for GALNT15 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14
    SP1:                          -           -                                   -                                             
    SP2:                          -           -                                   -                             -     -         
    SP3:                                                                                                                        
    SP4:                                                                                                                        
    SP5:                    -     -     -     -     -     -     -     -     -     -     -     -     -                           


    ECgene alternative splicing isoforms for GALNT15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GALNT15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    GALNT15 Expression
    About this image


    GALNT15 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Adult Endothelial Cells Blood Brain Barrier
             Cerebellum
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Adult Endothelial Cells Blood Brain Barrier
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Mesenchymal Stem Cells (Uncategorized)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Liver (Hepatobiliary System)
             Mature Mesothelial Cells Hepatic Mesenchyme
    GALNT15 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GALNT15 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.411308

    UniProtKB/Swiss-Prot: GLT15_HUMAN, Q8N3T1
    Tissue specificity: Widely expressed. Highly expressed in small intestine, placenta, spleen, cerebral cortex and
    ovary. Expressed at intermediate level in uterus, mammary gland, stomach, cerebellum and whole brain. Weakly
    expressed in fetal brain, bone marrow, thyroid gland, thymus, heart, skeletal muscle, lung, liver, colon,
    pancreas, kidney and testis. Not expressed in leukocyte. Expressed in both normal and osteoarthritic cartilage.
    Expressed at low level in chondrocytes in all zones of both normal and osteoarthritic cartilage

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for GALNT15 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Galnt151 , 5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like more5
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase more1
    82.42(n)1
    78.02(a)1
      14 (19.40 cM)5
    787541  NM_030166.31  NP_084442.11 
     320289895 
    chicken
    (Gallus gallus)
    Aves GALNTL21 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like more 66.82(n)
    59.15(a)
      420642  XM_004939390.1  XP_004939447.1 
    lizard
    (Anolis carolinensis)
    Reptilia GALNT156
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-a...
    57(a)
    1 ↔ 1
    6(35105847-35130421)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia galnt151 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase more 57(n)
    51.33(a)
      100489899  XM_002932790.2  XP_002932836.1 


    ENSEMBL Gene Tree for GALNT15 (if available)
    TreeFam Gene Tree for GALNT15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GALNT15 gene
    GALNT62  POC1B-GALNT42  GALNT122  GALNT52  GALNT72  GALNT12  GALNTL62  GALNT142  
    GALNT32  GALNTL52  GALNT102  GALNT22  GALNT42  GALNT132  GALNT162  GALNT112  
    Selected SIMAP similar genes for GALNT15 using alignment to 4 protein entries:     GLT15_HUMAN (see all proteins) (see all similar genes):
    GALNTL2    GALNT14    GALNTL6    POC1B-GALNT4    GALNT13    GALNT3
    GALNTL5    GALNT7    GALNT2    GalNAc-T10    GALNT10    GALNT12
    GALNT1    GALNT4    GALNT11    GALNT5    GalNAc-T16    GALNT6

    GALNT15 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GALNT15 (see all 1351)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs172001641,2
    C,F--16214241(+) ACTGTC/TCACTG 1 -- us2k16Minor allele frequency- T:0.02NA 266
    rs1903046031,2
    --16214282(+) CCACAC/TATAAC 1 -- us2k10--------
    rs789380141,2
    F--16214322(+) CACACG/TTGTAT 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1155736501,2
    C,F--16214342(+) TGCACG/ATGAGT 1 -- us2k11Minor allele frequency- A:0.05WA 118
    rs1158110551,2
    C,F--16214393(+) TCAAAA/CGGTAA 1 -- us2k11Minor allele frequency- C:0.05WA 118
    rs1437139291,2
    --16214417(+) ACAAAC/TATTTT 1 -- us2k10--------
    rs1162544451,2
    C,F--16214503(+) TCCCCC/GCTCCA 1 -- us2k11Minor allele frequency- G:0.05WA 118
    rs1825266541,2
    --16214548(+) CATCAC/GAAGAA 1 -- us2k10--------
    rs67765561,2
    H--16214676(+) gtctcA/Ccggct 1 -- us2k14Minor allele frequency- C:0.00NS EA 420
    rs1472293061,2
    --16214677(+) TCTCAC/TGGCTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GALNT15 (16216156 - 16273499 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for GALNT15: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GALNT15
    DNA2.0 Custom Variant and Variant Library Synthesis for GALNT15

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615131    OMIM disorders: --

    6 diseases for GALNT15:    
    About MalaCards
    hypertension    schizophrenia    cerebritis    thyroiditis
    hepatitis    endotheliitis


    GALNT15 for disorders           About GeneDecksing


    Export disorders for GALNT15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GALNT15 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with GALNT15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc- T15. (PubMed id 15147861)1, 2, 3 Cheng L.... Narimatsu H. (FEBS Lett. 2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries. (PubMed id 11597177)1, 2 Kumar S....Lark M.W. (Osteoarthritis Cartilage 2001)
    5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    6. Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. (PubMed id 20800603)1 Flachsbart F....Nebel A. (Mutat. Res. 2010)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    8. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    9. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 117248 HGNC: 21531 AceView: GALNTL2 Ensembl:ENSG00000131386 euGenes: HUgn117248
    ECgene: GALNT15 Kegg: 117248 H-InvDB: GALNT15

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for GALNT15 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=GALNT15
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_501

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GALNT15 gene:
    Search GeneIP for patents involving GALNT15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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