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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GALNT11 Gene

protein-coding   GIFtS: 53
GCID: GC07P151722

UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase...

  Search for GALNT11
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide
N-Acetylgalactosaminyltransferase 11 (GalNAc-T11)1 2
     EC 2.4.1.413 8
Polypeptide GalNAc Transferase 112 3     GALNAC-T112
Protein-UDP Acetylgalactosaminyltransferase 112 3     GALNACT112
Pp-GaNTase 112 3     Polypeptide N-Acetylgalactosaminyltransferase 112
UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 112 3     GalNAc-T113

External Ids:    HGNC: 198751   Entrez Gene: 639172   Ensembl: ENSG000001782347   OMIM: 6151305   UniProtKB: Q8NCW63   

Export aliases for GALNT11 gene to outside databases

Previous GC identifers: GC07P149969 GC07P151037 GC07P151114 GC07P151160 GC07P151353 GC07P145534


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for GALNT11 Gene: 
GALNT11 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)) is a protein-coding gene. Among its related super-pathways are Mucin type O-Glycan biosynthesis and Post-translational protein modification. GO annotations related to this gene include polypeptide N-acetylgalactosaminyltransferase activity. An important paralog of this gene is GALNT6.

UniProtKB/Swiss-Prot: GLT11_HUMAN, Q8NCW6
Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same
enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of
erythropoietin

Gene Wiki entry for GALNT11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007914.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GALNT11 gene promoter:
         ISGF-3   Pax-5   ATF-2   POU3F2 (N-Oct-5b)   CREB   POU2F1   deltaCREB   POU2F1a   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): GALNT11 promoter sequence
   Search SABiosciences Chromatin IP Primers for GALNT11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GALNT11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1|7q36.1   Ensembl cytogenetic band:  7q36.1   HGNC cytogenetic band: 7q36.1

GALNT11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GALNT11 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P151722:  view genomic region     (about GC identifiers)

Start:
151,722,759 bp from pter      End:
151,819,427 bp from pter
Size:
96,669 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 151,049,949-151,146,598     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GLT11_HUMAN, Q8NCW6 (See protein sequence)
Recommended Name: Polypeptide N-acetylgalactosaminyltransferase 11  
Size: 608 amino acids; 68919 Da
Cofactor: Manganese (By similarity)
Cofactor: Calcium (By similarity)
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)
Sequence caution: Sequence=BAB15338.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q6PCD1 Q9H6C2 Q9H6Z5 Q9UDR8
Alternative splicing: 2 isoforms:  Q8NCW6-1   Q8NCW6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GALNT11: NX_Q8NCW6

Explore proteomics data for GALNT11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NCW6

  • 4/13 DME Specific Peptides for GALNT11 (Q8NCW6) (see all 13)
     VVCPVID  RTVHSVI  MAGGLFA  PTMAGGL 

    GALNT11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GALNT11 Protein Expression
    REFSEQ proteins: NP_071370.2  
    ENSEMBL proteins: 
     ENSP00000395122   ENSP00000395020   ENSP00000414890   ENSP00000395078   ENSP00000393892  
     ENSP00000416787   ENSP00000410093   ENSP00000397581   ENSP00000412142   ENSP00000390247  
     ENSP00000393399   ENSP00000315835   ENSP00000389449  
    Reactome Protein details: Q8NCW6
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    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005794Golgi apparatus ----
    GO:0016021integral to membrane IEA--

    GALNT11 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GLT2: Glycosyltransferase family 2 domain containing

    3 InterPro protein domains:
     IPR000772 Ricin_B_lectin
     IPR001173 Glyco_trans_2
     IPR003859 Galactosyl_T_2_met

    Graphical View of Domain Structure for InterPro Entry Q8NCW6

    ProtoNet protein and cluster: Q8NCW6

    2 Blocks protein domains:
    IPB000772 Ricin B lectin domain
    IPB001173 Glycosyl transferase


    UniProtKB/Swiss-Prot: GLT11_HUMAN, Q8NCW6
    Domain: There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also
    called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal
    domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal
    binding (By similarity)
    Domain: The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity (By
    similarity)
    Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily
    Similarity: Contains 1 ricin B-type lectin domain


    GALNT11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GLT11_HUMAN, Q8NCW6
    Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an
    N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same
    enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of
    erythropoietin
    Catalytic activity: UDP-N-acetyl-alpha-D-galactosamine + polypeptide = UDP +
    N-acetyl-alpha-D-galactosaminyl-polypeptide

         Enzyme Number (IUBMB): EC 2.4.1.411 2

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004653polypeptide N-acetylgalactosaminyltransferase activity IEA--
    GO:0016740transferase activity ----
    GO:0016757transferase activity, transferring glycosyl groups ----
         
    GALNT11 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GALNT11 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.44
    Mucin type O-Glycan biosynthesis0.44
    2Asparagine N-linked glycosylation
    Post-translational protein modification0.44
    Metabolism of proteins0.35
    3Metabolism
    Metabolic pathways0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for GALNT11
        O-linked glycosylation of mucins
    Metabolism of proteins
    Post-translational protein modification


    2         Kegg Pathways  (Kegg details for GALNT11):
        Mucin type O-Glycan biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: GLT11_HUMAN, Q8NCW6
    Pathway: Protein modification; protein glycosylation


    GALNT11 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GALNT11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/36 Interacting proteins for GALNT11 (Q8NCW63 ENSP000003158354) via UniProtKB, MINT, STRING, and/or I2D (see all 36)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    MUC4Q991023, ENSP000003042074I2D: score=1 STRING: ENSP00000304207
    GALNT1ENSP000002691954STRING: ENSP00000269195
    GALNT12ENSP000003641504STRING: ENSP00000364150
    GALNT3ENSP000003764654STRING: ENSP00000376465
    GALNT5ENSP000002590564STRING: ENSP00000259056
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation ----
    GO:0016266O-glycan processing TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    GALNT11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GALNT11 (GLT11)

    3 HMDB Compounds for GALNT11    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Manganesemanganese 7439-96-5--
    Uridine diphosphate-N-acetylgalactosamineUDP-N-acetyl-D-galactosamine (see all 17)7277-98-7--

    Search CenterWatch for drugs/clinical trials and news about GALNT11 / GLT11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GALNT11 gene: 
    NM_022087.2  

    Unigene Cluster for GALNT11:

    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
    Hs.647109  [show with all ESTs]
    Unigene Representative Sequence: AK128545
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000482812 ENST00000430044(uc010lqg.1 uc011kvm.1) ENST00000431668
    ENST00000446096 ENST00000447778 ENST00000423337 ENST00000434507(uc003wku.2)
    ENST00000415421(uc003wkv.1) ENST00000419245 ENST00000447796 ENST00000491061(uc003wkw.1)
    ENST00000431940 ENST00000452146 ENST00000320311 ENST00000422997(uc011kvn.1)

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    Additional mRNA sequence: 

    AK025287.1 AK026056.1 AK124934.1 AK128545.1 AK296097.1 AK298911.1 BC059377.1 Y12434.3 

    12 DOTS entries:

    DT.104832  DT.86838948  DT.121095673  DT.121095590  DT.100723683  DT.101982278  DT.121095657  DT.95184222 
    DT.121095642  DT.121095585  DT.100814529  DT.92428564 

    24/90 AceView cDNA sequences (see all 90):

    AA369201 BI915669 AI985274 BM997197 AK026056 BC059377 BQ428160 BE349504 
    AI655754 AI801727 CA946877 AW517040 AK124934 BM998376 BU180419 AA721041 
    CD251710 AA333460 AK128545 AW102975 AI272007 BX499379 CD251775 BM826814 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for GALNT11 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16
    SP1:                    -                 -                                   -           -                                   -               
    SP2:                                      -                                                                                                   
    SP3:                                                                                                                                          
    SP4:              -     -     -     -     -                                                                                                   
    SP5:                    -     -           -                                                                                                   


    ECgene alternative splicing isoforms for GALNT11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GALNT11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTCCTTTC
    GALNT11 Expression
    About this image


    See GALNT11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GALNT11

    SOURCE GeneReport for Unigene cluster: Hs.647109

    UniProtKB/Swiss-Prot: GLT11_HUMAN, Q8NCW6
    Tissue specificity: Highly expressed in kidney. Expressed at intermediate level in brain, heart and skeletal
    muscle. Weakly expressed other tissues. In kidney, it is strongly expressed in tubules but not expressed in
    glomeruli

        SABiosciences Expression via Pathway-Focused PCR Array including GALNT11: 
              Glycosylation in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GALNT11 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Galnt111 , 5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase more1, 5 85.31(n)1
    87.83(a)1
      5 (12.35 cM)5
    2310501  NM_144908.31  NP_659157.11 
     252228825 
    chicken
    (Gallus gallus)
    Aves GALNT111 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase more 77.1(n)
    79.41(a)
      420436  XM_418541.3  XP_418541.2 
    lizard
    (Anolis carolinensis)
    Reptilia GALNT116
    Uncharacterized protein
    77(a)
    1 ↔ 1
    6(4229655-4256357)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.44262 Xenopus laevis transcribed sequence with weak similarity more 74.76(n)    CA792380.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sbcb9212 sbcb921 74.42(n)   378984  57074452 
    fruit fly
    (Drosophila melanogaster)
    Insecta Pgant35A1 Polypeptide N-acetylgalactosaminyltransferase 35A 53.1(n)
    50.51(a)
      48775  NM_143812.3  NP_652069.2 
    worm
    (Caenorhabditis elegans)
    Secernentea gly-111 Protein GLY-11 51.55(n)
    47.73(a)
      176647  NM_001027777.2  NP_001022948.1 


    ENSEMBL Gene Tree for GALNT11 (if available)
    TreeFam Gene Tree for GALNT11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GALNT11 gene
    GALNT62  POC1B-GALNT42  GALNT122  GALNT52  GALNT72  GALNT12  GALNTL62  GALNT142  
    GALNTL52  GALNT32  GALNT22  GALNT102  GALNT42  GALNT132  GALNT162  
    18/24 SIMAP similar genes for GALNT11 using alignment to 10 protein entries:     GLT11_HUMAN (see all proteins) (see all similar genes):
    GALNTL6    GALNT1    GALNT14    GALNT16    GalNAc-T16    GALNT9
    GALNT3    GALNT13    POC1B-GALNT4    GALNT2    GALNT4    GALNTL5
    GALNT6    GALNT7    GALNT15    GALNT18    GALNT19    GALNTL4

    GALNT11 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for GALNT11
    PGOHUM00000259465 PGOHUM00000259466


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1987 SNPs in GALNT11 are shown (see all 1987)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs354409521,2
    C--151767573(+) AGCATCT/-GTTTC 1 -- int11Minor allele frequency- -:0.50NA 2
    rs361043151,2
    C--151811005(+) AAGTG-/TTTTTT 1 -- int12Minor allele frequency- T:0.00NA CSA 4
    rs1436428061,2
    C--155171988(+) CGCTGA/GAAAGA 1 -- us2k10--------
    rs1471813741,2
    --155172169(+) TACTAC/TCAAGG 1 -- us2k10--------
    rs1406148801,2
    --155172330(+) AACACA/GCTCCA 1 -- us2k10--------
    rs1927627141,2
    --155172402(+) GTCTTA/CAAACT 1 -- us2k10--------
    rs784463571,2
    C,F--155172419(+) CTTGAG/ATATAT 1 -- us2k11Minor allele frequency- A:0.05EA 120
    rs1847861931,2
    --155172704(+) CATGAA/GCTGCA 1 -- us2k10--------
    rs1422186101,2
    --155172758(+) ACTGCC/TCTTGC 1 -- us2k10--------
    rs69751741,2
    C,F,H--155172855(+) CCAGCA/GGCAGT 1 -- us2k19Minor allele frequency- G:0.05NS EA NA WA 1106

    HapMap Linkage Disequilibrium report for GALNT11 (151722759 - 151819427 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for GALNT11:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2671400CNV Deletion23128226
    esv1004658CNV Deletion20482838
    esv2735443CNV Deletion23290073
    dgv7549n71CNV Gain21882294
    nsv889494CNV Gain21882294
    nsv889495CNV Gain21882294
    nsv831191CNV Gain17160897

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    1 SABiosciences qBiomarker Copy Number PCR Array containing GALNT11:
    Birth Defects
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    DNA2.0 Custom Variant and Variant Library Synthesis for GALNT11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GALNT11 for disorders           About MalaCards
    OMIM gene information: 615130    OMIM disorders: --


    GALNT11 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: GALNT11 (1 document)

    Export disorders for GALNT11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GALNT11 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with GALNT11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Functional conservation of subfamilies of putative UDP-N- acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila. (PubMed id 11925450)1, 2, 3 Schwientek T.... Clausen H. (2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    5. Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evo lutionary conserved human ortholog GalNAc-transferase-T11. (PubMed id 20422447)1 Bennett E.P....Clausen H. (2010)
    6. A Japanese-specific allele in the GALNT11 gene. (PubMed id 20547088)1 Yuasa I....Henke J. (2010)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
    9. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1 Scherer S.W.... Tsui L.-C. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 63917 HGNC: 19875 AceView: GALNT11 Ensembl:ENSG00000178234 euGenes: HUgn63917
    ECgene: GALNT11 Kegg: 63917 H-InvDB: GALNT11

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GALNT11 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_494

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GALNT11 gene:
    Search GeneIP for patents involving GALNT11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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