Aliases for GAL3ST4 Gene
External Ids for GAL3ST4 Gene
Previous GeneCards Identifiers for GAL3ST4 Gene
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates. [provided by RefSeq, Jul 2008]
GeneCards Summary for GAL3ST4 Gene
GAL3ST4 (Galactose-3-O-Sulfotransferase 4) is a Protein Coding gene. Diseases associated with GAL3ST4 include Idiopathic Scoliosis. Among its related pathways are Phase II conjugation. GO annotations related to this gene include galactosylceramide sulfotransferase activity and proteoglycan sulfotransferase activity. An important paralog of this gene is GAL3ST2.
UniProtKB/Swiss-Prot for GAL3ST4 Gene
Catalyzes the transfer of sulfate to beta-1,3-linked galactose residues in O-linked glycoproteins. Good substrates include asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc.