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Aliases for GAGE6 Gene

Aliases for GAGE6 Gene

  • G Antigen 6 2 3
  • Cancer/Testis Antigen 4.6 3 4
  • GAGE-6 3 4
  • CT4.6 3 4
  • Cancer/Testis Antigen Family 4, Member 6 3
  • Cancer/Testis Antigen Family 4 2
  • Member 6 2

External Ids for GAGE6 Gene

Previous GeneCards Identifiers for GAGE6 Gene

  • GC0XP047421
  • GC0XP048026
  • GC0XP048254
  • GC0XP048259
  • GC0XP049030
  • GC0XP049035
  • GC0XP049212
  • GC0XP049356
  • GC0XP049365

Summaries for GAGE6 Gene

Entrez Gene Summary for GAGE6 Gene

  • This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]

GeneCards Summary for GAGE6 Gene

GAGE6 (G Antigen 6) is a Protein Coding gene. Among its related pathways are Innate Lymphoid Cell Differentiation Pathways.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE6 Gene

Genomics for GAGE6 Gene

Genomic Location for GAGE6 Gene

Chromosome:
X
Orientation:
Unknown strand

Genomic View for GAGE6 Gene


Cytogenetic band:
  • Xp11.4-p11.2 by Entrez Gene
  • Xp11.4-p11.2 not on reference assembly by HGNC
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for GAGE6 Gene

Proteins for GAGE6 Gene

  • Protein details for GAGE6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13070-GAGE6_HUMAN
    Recommended name:
    G antigen 6
    Protein Accession:
    Q13070

    Protein attributes for GAGE6 Gene

    Size:
    117 amino acids
    Molecular mass:
    12892 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene belongs to a family of genes organized in clustered repeats. They have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.

neXtProt entry for GAGE6 Gene

Proteomics data for GAGE6 Gene at MOPED

Post-translational modifications for GAGE6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE6 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for GAGE6 Gene

Domains & Families for GAGE6 Gene

Protein Domains for GAGE6 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for GAGE6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13070

UniProtKB/Swiss-Prot:

GAGE6_HUMAN :
  • Belongs to the GAGE family.
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE6: view

No data available for Gene Families for GAGE6 Gene

Function for GAGE6 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GAGE6 Gene

Localization for GAGE6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GAGE6 Gene

Pathways & Interactions for GAGE6 Gene

genes like me logo Genes that share pathways with GAGE6: view

Pathways by source for GAGE6 Gene

1 R&D Systems pathway for GAGE6 Gene

Interacting Proteins for GAGE6 Gene

Gene Ontology (GO) - Biological Process for GAGE6 Gene

None

No data available for SIGNOR curated interactions for GAGE6 Gene

Drugs & Compounds for GAGE6 Gene

No Compound Related Data Available

Transcripts for GAGE6 Gene

Unigene Clusters for GAGE6 Gene

G antigen 6:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE6 Gene

No ASD Table

Relevant External Links for GAGE6 Gene

ECgene alternative splicing isoforms for
GAGE6

Expression for GAGE6 Gene

mRNA expression in normal human tissues for GAGE6 Gene

SOURCE GeneReport for Unigene cluster for GAGE6 Gene Hs.632808

mRNA Expression by UniProt/SwissProt for GAGE6 Gene

Q13070-GAGE6_HUMAN
Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except testis.
genes like me logo Genes that share expression patterns with GAGE6: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for GAGE6 Gene

Orthologs for GAGE6 Gene

No data available for Orthologs and Evolution for GAGE6 Gene

Paralogs for GAGE6 Gene

genes like me logo Genes that share paralogs with GAGE6: view

No data available for Paralogs for GAGE6 Gene

Variants for GAGE6 Gene

Structural Variations from Database of Genomic Variants (DGV) for GAGE6 Gene

Variant ID Type Subtype PubMed ID
nsv820429 CNV Deletion 20802225
esv28941 CNV Gain+Loss 19812545

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for GAGE6 Gene

Disorders for GAGE6 Gene

Relevant External Links for GAGE6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GAGE6

No disorders were found for GAGE6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAGE6 Gene

Publications for GAGE6 Gene

  1. A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. (PMID: 7544395) van den Eynde B. … Boon T. (J. Exp. Med. 1995) 2 3 4 67
  2. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff M.F. … Ditzel H.J. (Tissue Antigens 2008) 3
  3. Characterization of the GAGE genes that are expressed in various human cancers and in normal testis. (PMID: 10397259) De Backer O. … van der Bruggen P. (Cancer Res. 1999) 3
  4. Isolation and characterization of PAGE-1 and GAGE-7: new genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens. (PMID: 9651357) Chen M.E. … Sikes R.A. (J. Biol. Chem. 1998) 3

Products for GAGE6 Gene

Sources for GAGE6 Gene

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