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Aliases for GAGE5 Gene

Aliases for GAGE5 Gene

  • G Antigen 5 2 3
  • Cancer/Testis Antigen 4.5 3 4
  • GAGE-5 3 4
  • CT4.5 3 4
  • Cancer/Testis Antigen Family 4, Member 5 3
  • Cancer/Testis Antigen Family 4 2
  • Member 5 2

External Ids for GAGE5 Gene

Previous GeneCards Identifiers for GAGE5 Gene

  • GC0XP048025
  • GC0XP048253
  • GC0XP048258
  • GC0XP049029
  • GC0XP049034
  • GC0XP049105
  • GC0XP049089
  • GC0XP049215
  • GC0XP049354
  • GC0XP049364

Summaries for GAGE5 Gene

Entrez Gene Summary for GAGE5 Gene

  • This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]

GeneCards Summary for GAGE5 Gene

GAGE5 (G Antigen 5) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE5 Gene

Genomics for GAGE5 Gene

Genomic Location for GAGE5 Gene

Orientation:
Unknown strand

Genomic View for GAGE5 Gene

Cytogenetic band:
  • Xp11.4-p11.2 by Entrez Gene
  • Xp11.4-p11.2 not on reference assembly by HGNC

RefSeq DNA sequence for GAGE5 Gene

No data available for Regulatory Elements for GAGE5 Gene

Proteins for GAGE5 Gene

  • Protein details for GAGE5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13069-GAGE5_HUMAN
    Recommended name:
    G antigen 5
    Protein Accession:
    Q13069
    Secondary Accessions:
    • Q6FG72

    Protein attributes for GAGE5 Gene

    Size:
    117 amino acids
    Molecular mass:
    12924 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene belongs to a family of genes organized in clustered repeats. They have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells

neXtProt entry for GAGE5 Gene

Proteomics data for GAGE5 Gene at MOPED

Post-translational modifications for GAGE5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE5 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for GAGE5 Gene

Domains for GAGE5 Gene

Protein Domains for GAGE5 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for GAGE5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13069

UniProtKB/Swiss-Prot:

GAGE5_HUMAN :
  • Q13069
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE5: view

No data available for Gene Families for GAGE5 Gene

Function for GAGE5 Gene

Gene Ontology (GO) - Molecular Function for GAGE5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with GAGE5: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for GAGE5 Gene

Localization for GAGE5 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GAGE5 Gene

Pathways for GAGE5 Gene

SuperPathways for GAGE5 Gene

No Data Available

Interacting Proteins for GAGE5 Gene

Gene Ontology (GO) - Biological Process for GAGE5 Gene

None

No data available for Pathways by source for GAGE5 Gene

Transcripts for GAGE5 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE5 Gene

No ASD Table

Relevant External Links for GAGE5 Gene

ECgene alternative splicing isoforms for
GAGE5

Expression for GAGE5 Gene

mRNA expression in normal human tissues for GAGE5 Gene

mRNA Expression by UniProt/SwissProt for GAGE5 Gene

Q13069-GAGE5_HUMAN
Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except testis
genes like me logo Genes that share expressions with GAGE5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein expression for GAGE5 Gene

Orthologs for GAGE5 Gene

No data available for Orthologs and Evolution for GAGE5 Gene

Paralogs for GAGE5 Gene

genes like me logo Genes that share paralogs with GAGE5: view

No data available for Paralogs for GAGE5 Gene

Variants for GAGE5 Gene

Structural Variations from Database of Genomic Variants (DGV) for GAGE5 Gene

Variant ID Type Subtype PubMed ID
esv24944 CNV Gain+Loss 19812545
nsv821250 CNV Deletion 20802225

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for GAGE5 Gene

Disorders for GAGE5 Gene

No disorders were found for GAGE5 Gene.

No data available for UniProtKB/Swiss-Prot for GAGE5 Gene

Publications for GAGE5 Gene

  1. A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. (PMID: 7544395) van den Eynde B. … Boon T. (J. Exp. Med. 1995) 2 3 4
  2. Characterization of the GAGE genes that are expressed in various human cancers and in normal testis. (PMID: 10397259) De Backer O. … van der Bruggen P. (Cancer Res. 1999) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff M.F. … Ditzel H.J. (Tissue Antigens 2008) 3 4
  5. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PMID: 21044950) Lee O.H. … Songyang Z. (Mol. Cell Proteomics 2011) 3

Products for GAGE5 Gene

Sources for GAGE5 Gene

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