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Aliases & Descriptions for GAGE4
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| CT4.4 1, 2, 3 | | GAGE-4 3 | | OTTHUMP00000070307 2 |
| | | Descriptions |
|---|
| Cancer/testis antigen 4.4 3 | | G antigen 4 2 | | cancer/testis antigen family 4, member 4 2 |
|
| | Search outside databases for aliases for GAGE4 genePrevious GC identifers: GC0XU990067 GC0XP047420 GC0XP048024 GC0XP048252 GC0XP049028 GC0XP049103 GC0XP049056 GC0XP049069 GC0XP049088 |
Summaries for GAGE4(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for GAGE4: This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq]
|
Genomic Location for GAGE4
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.4-p11.2 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.4-p11.2GAGE4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP049213:
(about GC identifiers)
Start:
|
49,212,424 bp from pter |
End:
|
49,229,298 bp from pter |
Size:
|
16,875 bases |
Orientation:
|
plus strand |
3 alternative locations:
| ChrX+ 49,241,043-49,260,086 | ChrX+ 49,084,570-49,120,425 | ChrX+ 49,202,856-49,219,752 | |
| Proteins for GAGE4
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: GAGE4_HUMAN, Q13068 (See
protein sequence)Recommended Name: G antigen 4 Size: 117 amino acids; 12885 Da
Secondary accessions: Q6NT33Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_001465.1
ENSEMBL proteins: ENSP00000384507 ENSP00000385617 ENSP00000365339
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for GAGE4: Assays for GAGE4: | Protein
Domains/ Families for GAGE4(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q13068
ProtoNet protein and cluster: Q13068 1 Blocks protein family: IPB008625 GAGE
UniProtKB/Swiss-Prot: GAGE4_HUMAN, Q13068Similarity: Belongs to the GAGE family | Gene Function for GAGE4
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001474
Applied Biosystems Silencer® siRNAs for GAGE4
Sigma-Aldrich siRNA for GAGE4  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001474                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_001474                                  untagged cDNA clone in CMV expression vector: NM_001474 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001474
| Pathways & Interactions for GAGE4
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| -- |
Drugs & Compounds for GAGE4(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for GAGE4
|
Transcripts for GAGE4(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001474
Sigma-Aldrich siRNA for GAGE4  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_001474 REFSEQ mRNAs for GAGE4 gene: NM_001474.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001474               OriGene GFP tagged cDNA clone in CMV expression vector: NM_001474                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_001474                                  untagged cDNA clone in CMV expression vector: NM_001474  24/29 AceView cDNA sequences (see all 29
):U19145 BM832793 BC024914 NM_001474 NM_001472 AF055473 AW016546 BX108227 BC069309 CF780547 U19143 AW510753 AA447559 BC005363 BX283580 NM_012196 BC018052 BM836228 AA738037 BP431265 BG208433 BG206349 BG120838 AW102587
highest scoring ESTs for GAGE4:CF780497 BC081536 EC473459
GeneLoc Exon Structure
3 Ensembl transcripts including schematic representations: ENST00000406001
ENST00000407783
ENST00000376169
|
Expression for GAGE4
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| GAGE4 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for GAGE4
1 / 2 / 3 16 probe-sets matching GAGE4 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: -- UniProtKB/Swiss-Prot: GAGE4_HUMAN, Q13068Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except testis |
Orthologs for GAGE4
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for GAGE4 | Paralogs for GAGE4(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for GAGE4 gene
- XAGE32 GAGE2D2 GAGE102 GAGE12H2 ENSG000001691642 XAGE52 XAGE2B2 GAGE12E2
- GAGE12C2 GAGE2E2 GAGE12 GAGE2C2 GAGE12F2 GAGE132 PAGE12 XAGE22
- GAGE2B2 GAGE2A2 GAGE12J2
|
SNPs/Variants for GAGE4(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations for GAGE4
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 300597
|
Medical News for GAGE4(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for GAGE4 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 6 PubMed articles for GAGE4 gene: |
Search for GAGE4
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing GAGE4
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing GAGE4
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GAGE4(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for GAGE4(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for GAGE4:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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