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Aliases for GAGE3 Gene

Aliases for GAGE3 Gene

  • G Antigen 3 2 3
  • Cancer/Testis Antigen 4.3 3 4
  • GAGE-3 3 4
  • CT4.3 3 4
  • Cancer/Testis Antigen Family 4, Member 3 3
  • Cancer/Testis Antigen Family 4 2
  • Member 3 2

External Ids for GAGE3 Gene

Previous GeneCards Identifiers for GAGE3 Gene

  • GC0XP047426
  • GC0XP048023
  • GC0XP048214
  • GC0XP048257
  • GC0XP048934
  • GC0XP049221
  • GC0XP049107
  • GC0XP049086
  • GC0XP049355

Summaries for GAGE3 Gene

Entrez Gene Summary for GAGE3 Gene

  • This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]

GeneCards Summary for GAGE3 Gene

GAGE3 (G Antigen 3) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE3 Gene

Genomics for GAGE3 Gene

Genomic Location for GAGE3 Gene

Chromosome:
X
Orientation:
Unknown strand

Genomic View for GAGE3 Gene


Cytogenetic band:
  • Xp11.23 not on reference assembly by Entrez Gene
  • Xp11.23 not on reference assembly by HGNC
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for GAGE3 Gene

Proteins for GAGE3 Gene

  • Protein details for GAGE3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13067-GAGE3_HUMAN
    Recommended name:
    G antigen 3
    Protein Accession:
    Q13067

    Protein attributes for GAGE3 Gene

    Size:
    118 amino acids
    Molecular mass:
    12937 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene belongs to a family of genes organized in clustered repeats. They have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.

neXtProt entry for GAGE3 Gene

Proteomics data for GAGE3 Gene at MOPED

Post-translational modifications for GAGE3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for GAGE3 Gene

Domains & Families for GAGE3 Gene

Protein Domains for GAGE3 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for GAGE3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13067

UniProtKB/Swiss-Prot:

GAGE3_HUMAN :
  • Belongs to the GAGE family.
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE3: view

No data available for Gene Families for GAGE3 Gene

Function for GAGE3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GAGE3 Gene

Localization for GAGE3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GAGE3 Gene

Pathways & Interactions for GAGE3 Gene

SuperPathways for GAGE3 Gene

No Data Available

Interacting Proteins for GAGE3 Gene

Gene Ontology (GO) - Biological Process for GAGE3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GAGE3 Gene

Drugs & Compounds for GAGE3 Gene

No Compound Related Data Available

Expression for GAGE3 Gene

mRNA expression in normal human tissues for GAGE3 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for GAGE3 Gene



mRNA Expression by UniProt/SwissProt for GAGE3 Gene

Q13067-GAGE3_HUMAN
Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except testis.
genes like me logo Genes that share expression patterns with GAGE3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Protein tissue co-expression partners for GAGE3 Gene

Orthologs for GAGE3 Gene

No data available for Orthologs and Evolution for GAGE3 Gene

Paralogs for GAGE3 Gene

genes like me logo Genes that share paralogs with GAGE3: view

No data available for Paralogs for GAGE3 Gene

Variants for GAGE3 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for GAGE3 Gene

Disorders for GAGE3 Gene

Relevant External Links for GAGE3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GAGE3

No disorders were found for GAGE3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAGE3 Gene

Publications for GAGE3 Gene

  1. A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. (PMID: 7544395) van den Eynde B. … Boon T. (J. Exp. Med. 1995) 2 3 4 67
  2. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff M.F. … Ditzel H.J. (Tissue Antigens 2008) 3
  3. Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. (PMID: 12522270) Salomon A.R. … Peters E.C. (Proc. Natl. Acad. Sci. U.S.A. 2003) 3
  4. Characterization of the GAGE genes that are expressed in various human cancers and in normal testis. (PMID: 10397259) De Backer O. … van der Bruggen P. (Cancer Res. 1999) 3
  5. Isolation and characterization of PAGE-1 and GAGE-7: new genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens. (PMID: 9651357) Chen M.E. … Sikes R.A. (J. Biol. Chem. 1998) 3

Products for GAGE3 Gene

Sources for GAGE3 Gene

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