 |
 | Services
| |
 |
Aliases & Descriptions for GAGE3
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| CT4.3 1, 2, 3 | | GAGE-3 3 |
| | | Descriptions |
|---|
| Cancer/testis antigen 4.3 3 | | G antigen 3 2 | | cancer/testis antigen family 4, member 3 2 |
|
| | Search outside databases for aliases for GAGE3 genePrevious GC identifers: GC0XU990066 GC0XP047426 GC0XP048023 GC0XP048214 GC0XP048257 GC0XP048934 GC0XP049107 GC0XP049086 |
Summaries for GAGE3(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for GAGE3: This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq]
|
Genomic Location for GAGE3
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.4-p11.2 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.4-p11.2GAGE3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP049221:
(about GC identifiers)
Start:
|
49,212,424 bp from pter |
End:
|
49,229,298 bp from pter |
Size:
|
16,875 bases |
Orientation:
|
plus strand |
3 alternative locations:
| ChrX+ 49,241,043-49,260,086 | ChrX+ 49,084,570-49,120,425 | ChrX+ 49,202,856-49,219,752 | |
| Proteins for GAGE3
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: GAGE3_HUMAN, Q13067 (See
protein sequence)Recommended Name: G antigen 3 Size: 118 amino acids; 12937 DaPost-translational modifications:
View phosphorylation sites using PhosphoSite2
ENSEMBL proteins: ENSP00000384507 ENSP00000385617 ENSP00000365339
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for GAGE3: Assays for GAGE3: | Protein
Domains/ Families for GAGE3(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q13067
ProtoNet protein and cluster: Q13067 1 Blocks protein family: IPB008625 GAGE
UniProtKB/Swiss-Prot: GAGE3_HUMAN, Q13067Similarity: Belongs to the GAGE family | Gene Function for GAGE3
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|                  Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Browse siRNA at Sigma-Aldrich  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
Browse Origene for untagged/tagged cDNA clones in CMV expression vector
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers                  Browse Origene genome-wide validated SYBR primer pairs
| Pathways & Interactions for GAGE3
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| -- |
Drugs & Compounds for GAGE3(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for GAGE3
|
Transcripts for GAGE3(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene) About This Section
|                  Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Browse siRNA at Sigma-Aldrich  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
Browse Origene for untagged/tagged cDNA clones in CMV expression vector
GeneLoc Exon Structure
3 Ensembl transcripts including schematic representations: ENST00000406001
ENST00000407783
ENST00000376169
|
Expression for GAGE3
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| GAGE3 expression in normal and diseased human tissues
1 / 2 / 3 11 probe-sets matching GAGE3 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
Expression variation in blood from EXPOLDB for GAGE3 UniProtKB/Swiss-Prot: GAGE3_HUMAN, Q13067Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except testis |
Orthologs for GAGE3
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for GAGE3 | Paralogs for GAGE3(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for GAGE3 gene
- XAGE32 GAGE2D2 GAGE102 GAGE12H2 ENSG000001691642 XAGE52 XAGE2B2 GAGE12E2
- GAGE12C2 GAGE2E2 GAGE12 GAGE2C2 GAGE12F2 GAGE132 PAGE12 XAGE22
- GAGE2B2 GAGE2A2 GAGE12J2
|
SNPs/Variants for GAGE3(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations for GAGE3
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 300596
|
Medical News for GAGE3(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for GAGE3 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 5 PubMed articles for GAGE3 gene: |
Search for GAGE3
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing GAGE3
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing GAGE3
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GAGE3(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for GAGE3(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for GAGE3:

 | |
 | | | | |
|
 |  |  |
| | | | Search Tocris compounds for GAGE3 |
|
 |
 | | | |
GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
|