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Aliases for GAGE2E Gene

Aliases for GAGE2E Gene

  • G Antigen 2E 2 3 5
  • GAGE-2E 3 4
  • GAGE8 3

External Ids for GAGE2E Gene

Previous GeneCards Identifiers for GAGE2E Gene

  • GC0XU900863
  • GC0XP049087
  • GC0XP049091
  • GC0XP049199
  • GC0XP049207
  • GC0XP049210
  • GC0XP049224
  • GC0XP049227
  • GC0XP049238
  • GC0XP049248
  • GC0XP049254
  • GC0XP049259
  • GC0XP049264
  • GC0XP049562

Summaries for GAGE2E Gene

GeneCards Summary for GAGE2E Gene

GAGE2E (G Antigen 2E) is a Protein Coding gene. An important paralog of this gene is XAGE5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE2E Gene

Genomics for GAGE2E Gene

Genomic Location for GAGE2E Gene

Chromosome:
X
Start:
49,341,192 bp from pter
End:
49,345,922 bp from pter
Size:
4,731 bases
Orientation:
Plus strand

Genomic View for GAGE2E Gene

Genes around GAGE2E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GAGE2E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GAGE2E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GAGE2E Gene

No data available for Regulatory Elements for GAGE2E Gene

Proteins for GAGE2E Gene

  • Protein details for GAGE2E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4V326-GAG2E_HUMAN
    Recommended name:
    G antigen 2E
    Protein Accession:
    Q4V326
    Secondary Accessions:
    • A6NFB1

    Protein attributes for GAGE2E Gene

    Size:
    116 amino acids
    Molecular mass:
    12763 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene belongs to a multigene family expressed in a large variety of tumors whereas in normal tissues, expression is restricted to germ cells. These genes organized in clustered repeats, have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.

neXtProt entry for GAGE2E Gene

Proteomics data for GAGE2E Gene at MOPED

Post-translational modifications for GAGE2E Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE2E Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GAGE2E Gene

Domains & Families for GAGE2E Gene

Protein Domains for GAGE2E Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for GAGE2E Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q4V326

UniProtKB/Swiss-Prot:

GAG2E_HUMAN :
  • Belongs to the GAGE family.
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE2E: view

No data available for Gene Families for GAGE2E Gene

Function for GAGE2E Gene

Animal Model Products

CRISPR Products

miRNA for GAGE2E Gene

miRTarBase miRNAs that target GAGE2E

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GAGE2E Gene

Localization for GAGE2E Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GAGE2E Gene COMPARTMENTS Subcellular localization image for GAGE2E gene
Compartment Confidence
nucleus 3
cytosol 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for GAGE2E Gene

Pathways & Interactions for GAGE2E Gene

SuperPathways for GAGE2E Gene

No Data Available

Interacting Proteins for GAGE2E Gene

Selected Interacting proteins: Q4V326-GAG2E_HUMAN for GAGE2E Gene via I2D

Symbol External ID(s) Details
KIAA1524

Gene Ontology (GO) - Biological Process for GAGE2E Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GAGE2E Gene

Drugs & Compounds for GAGE2E Gene

No Compound Related Data Available

Transcripts for GAGE2E Gene

mRNA/cDNA for GAGE2E Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(29) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GAGE2E Gene

G antigen 2E:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE2E Gene

No ASD Table

Relevant External Links for GAGE2E Gene

GeneLoc Exon Structure for
GAGE2E
ECgene alternative splicing isoforms for
GAGE2E

Expression for GAGE2E Gene

mRNA expression in normal human tissues for GAGE2E Gene

mRNA differential expression in normal tissues according to GTEx for GAGE2E Gene

This gene is overexpressed in Testis (x52.2).

SOURCE GeneReport for Unigene cluster for GAGE2E Gene Hs.695911

genes like me logo Genes that share expression patterns with GAGE2E: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for GAGE2E Gene

Orthologs for GAGE2E Gene

Evolution for GAGE2E Gene

ENSEMBL:
Gene Tree for GAGE2E (if available)
TreeFam:
Gene Tree for GAGE2E (if available)

No data available for Orthologs for GAGE2E Gene

Paralogs for GAGE2E Gene

genes like me logo Genes that share paralogs with GAGE2E: view

Variants for GAGE2E Gene

Structural Variations from Database of Genomic Variants (DGV) for GAGE2E Gene

Variant ID Type Subtype PubMed ID
esv24944 CNV Gain+Loss 19812545
nsv821250 CNV Deletion 20802225
nsv6897 CNV Insertion 18451855
nsv515202 CNV Complex 21397061
nsv820429 CNV Deletion 20802225
esv28941 CNV Gain+Loss 19812545

Relevant External Links for GAGE2E Gene

HapMap Linkage Disequilibrium report
GAGE2E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for GAGE2E Gene

Disorders for GAGE2E Gene

Relevant External Links for GAGE2E

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GAGE2E

No disorders were found for GAGE2E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAGE2E Gene

Publications for GAGE2E Gene

  1. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff M.F. … Ditzel H.J. (Tissue Antigens 2008) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for GAGE2E Gene

Sources for GAGE2E Gene

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