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Aliases for GAGE2E Gene

Aliases for GAGE2E Gene

  • G Antigen 2E 2 3
  • GAGE-2E 3 4
  • GAGE8 3

External Ids for GAGE2E Gene

Previous GeneCards Identifiers for GAGE2E Gene

  • GC0XU900863
  • GC0XP049087
  • GC0XP049091
  • GC0XP049199
  • GC0XP049207
  • GC0XP049210
  • GC0XP049224
  • GC0XP049227
  • GC0XP049238
  • GC0XP049248
  • GC0XP049254
  • GC0XP049259
  • GC0XP049264

Summaries for GAGE2E Gene

GeneCards Summary for GAGE2E Gene

GAGE2E (G Antigen 2E) is a Protein Coding gene. An important paralog of this gene is GAGE2C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE2E Gene

Genomics for GAGE2E Gene

Genomic Location for GAGE2E Gene

Start:
49,560,886 bp from pter
End:
49,568,208 bp from pter
Size:
7,323 bases
Orientation:
Plus strand

Genomic View for GAGE2E Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GAGE2E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GAGE2E Gene

No data available for Regulatory Elements for GAGE2E Gene

Proteins for GAGE2E Gene

  • Protein details for GAGE2E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4V326-GAG2E_HUMAN
    Recommended name:
    G antigen 2E
    Protein Accession:
    Q4V326
    Secondary Accessions:
    • A6NFB1

    Protein attributes for GAGE2E Gene

    Size:
    116 amino acids
    Molecular mass:
    12763 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene belongs to a multigene family expressed in a large variety of tumors whereas in normal tissues, expression is restricted to germ cells. These genes organized in clustered repeats, have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells

neXtProt entry for GAGE2E Gene

Proteomics data for GAGE2E Gene at MOPED

Post-translational modifications for GAGE2E Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE2E Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GAGE2E Gene

Domains for GAGE2E Gene

Protein Domains for GAGE2E Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for GAGE2E Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q4V326

UniProtKB/Swiss-Prot:

GAG2E_HUMAN :
  • Q4V326
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE2E: view

No data available for Gene Families for GAGE2E Gene

Function for GAGE2E Gene

miRNA for GAGE2E Gene

miRTarBase miRNAs that target GAGE2E

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for GAGE2E Gene

Localization for GAGE2E Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GAGE2E Gene COMPARTMENTS Subcellular localization image for GAGE2E gene
Compartment Confidence
nucleus 3
cytosol 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for GAGE2E Gene

Pathways for GAGE2E Gene

SuperPathways for GAGE2E Gene

No Data Available

Interacting Proteins for GAGE2E Gene

Selected Interacting proteins: Q4V326-GAG2E_HUMAN for GAGE2E Gene via I2D

Symbol External ID(s) Details
KIAA1524

Gene Ontology (GO) - Biological Process for GAGE2E Gene

None

No data available for Pathways by source for GAGE2E Gene

Transcripts for GAGE2E Gene

mRNA/cDNA for GAGE2E Gene

(29) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GAGE2E Gene

G antigen 2E:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE2E Gene

No ASD Table

Relevant External Links for GAGE2E Gene

GeneLoc Exon Structure for
GAGE2E
ECgene alternative splicing isoforms for
GAGE2E

Expression for GAGE2E Gene

mRNA expression in normal human tissues for GAGE2E Gene

mRNA differential expression in normal tissues according to GTEx for GAGE2E Gene

This gene is overexpressed in Testis (52.2).

SOURCE GeneReport for Unigene cluster for GAGE2E Gene Hs.695911

genes like me logo Genes that share expressions with GAGE2E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for GAGE2E Gene

Orthologs for GAGE2E Gene

Evolution for GAGE2E Gene

ENSEMBL:
Gene Tree for GAGE2E (if available)
TreeFam:
Gene Tree for GAGE2E (if available)

No data available for Orthologs for GAGE2E Gene

Paralogs for GAGE2E Gene

Paralogs for GAGE2E Gene

genes like me logo Genes that share paralogs with GAGE2E: view

Variants for GAGE2E Gene

Structural Variations from Database of Genomic Variants (DGV) for GAGE2E Gene

Variant ID Type Subtype PubMed ID
esv24944 CNV Gain+Loss 19812545
nsv821250 CNV Deletion 20802225
nsv6897 CNV Insertion 18451855
nsv515202 CNV Complex 21397061
nsv820429 CNV Deletion 20802225
esv28941 CNV Gain+Loss 19812545

Relevant External Links for GAGE2E Gene

HapMap Linkage Disequilibrium report
GAGE2E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for GAGE2E Gene

Disorders for GAGE2E Gene

No disorders were found for GAGE2E Gene.

No data available for UniProtKB/Swiss-Prot for GAGE2E Gene

Publications for GAGE2E Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  2. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff M.F. … Ditzel H.J. (Tissue Antigens 2008) 3 4
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Isolation and characterization of PAGE-1 and GAGE-7: new genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens. (PMID: 9651357) Chen M.E. … Sikes R.A. (J. Biol. Chem. 1998) 3

Products for GAGE2E Gene

Sources for GAGE2E Gene

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