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GAGE2E Gene

protein-coding   GIFtS: 34

GC0XP049087
G antigen 2E
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
GAGE8 1, 2
Descriptions
G antigen 2E 2
Putative uncharacterized protein GAGE2E 4
External Ids
HGNC: 319601
Entrez Gene: 267492
UniProtKB: Q4V3264
Ensembl: ENSG000002220237
Search outside databases for aliases for GAGE2E gene

Previous GC identifer: GC0XU900863

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.23

GAGE2E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP049087:     (about GC identifiers)

Start:
49,084,527 bp from pter
End:
49,091,867 bp from pter
Size:
7,341 bases
Orientation:
plus strand
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/TrEMBL: Q4V326 (See protein sequence)
Recommended Name: G antigen 2E  
Size: 116 amino acids; 12763 Da
Secondary accessions: A6NFB1

REFSEQ proteins: NP_001120672.1  

ENSEMBL proteins: 
ENSP00000365350 


Human Recombinant Proteins 
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Browse recombinant and purified proteins available from Enzo Life Sciences
Browse Abcam for Recombinant Proteins
Browse Abnova for Human Recombinant Proteins
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 


Antibodies for GAGE2E: 
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Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
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Search Novus for antibodies for GAGE2E

Assays for GAGE2E: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro domain/family:
 IPR008625 GAGE


   GeneDecks  GAGE2E for the domains selected above  
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Graphical View of Domain Structure for InterPro Entry Q4V326

ProtoNet protein and cluster: Q4V326

1 Blocks protein family: IPB008625 GAGE

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib.
RNA:
Browse Invitrogen for RNAi
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001127200

              Applied Biosystems Silencer® siRNAs for GAGE2E

              Sigma-Aldrich siRNA for GAGE2E  
                     Sigma-Aldrich shRNA for GAGE2E  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Invitrogen Clones for GAGE2E
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001127200
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001127200
                                 untagged cDNA clones in CMV expression vector (see all 2): BC018052 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_001127200

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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  --
(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for GAGE2E

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib.
RNA:
Browse Invitrogen for RNAi
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001127200

              Sigma-Aldrich siRNA for GAGE2E  
                     Sigma-Aldrich shRNA for GAGE2E  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_001127200  

REFSEQ mRNAs for GAGE2E gene: 

NM_001127200.1   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_001127200  

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001127200
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001127200
                                 untagged cDNA clones in CMV expression vector (see all 2): BC018052 

1 DOTS entry:

DT.444944 

24/29 AceView cDNA sequences (see all 29 ):

NM_001474 BC024914 BM832793 U19145 BM836228 BC069309 NM_012196 AA447559 
CF780547 NM_001472 BC018052 AW510753 BC005363 AF055473 BX108227 BX283580 
AW016546 U19143 BP431265 BG208433 BG120838 AA738037 BG206349 AW102587 

Unigene Cluster for GAGE2E:

G antigen 2E
Hs.695911
Unigene Representative Sequence: NM_001127200


GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:
ENST00000376179  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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GAGE2E expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for GAGE2E

1 / 2

15 probe-sets matching GAGE2E gene


Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
31497_at2 U95-A 23 1.00 0.10 0.39 2.10 -- -- -- -- --

33671_f_at2 U95-A 24 1.00 0.04 0.86 0.60 -- -- -- -- --

31960_f_at2 U95-A 24 1.00 0.04 0.72 0.66 -- -- -- -- --

33680_f_at2 U95-A 24 1.00 0.04 0.50 0.55 -- -- -- -- --

37065_f_at2 U95-A 24 0.94 0.04 0.61 0.88 -- -- -- -- --

31498_f_at2 U95-A 24 0.94 0.04 0.73 0.92 -- -- -- -- --

31954_f_at2 U95-A 23 0.94 0.04 0.62 0.32 -- -- -- -- --

207739_s_at2 U133-A 23 1.00 0.04 -- -- -- -- -- -- --

208235_x_at2 U133-A 23 0.82 0.04 -- -- -- -- -- -- --

207086_x_at2 U133-A 23 0.82 0.04 -- -- -- -- -- -- --

206640_x_at2 U133-A 23 0.82 0.04 -- -- -- -- -- -- --

207739_s_at2 U133Plus2 23 1.00 0.04 -- -- -- -- -- -- --

208235_x_at2 U133Plus2 23 0.82 0.04 -- -- -- -- -- -- --

207086_x_at2 U133Plus2 23 0.82 0.04 -- -- -- -- -- -- --

206640_x_at2 U133Plus2 23 0.82 0.04 -- -- -- -- -- -- --
GeneDecks  GAGE2E for binary patterns associated with the probe-sets selected above  
About GeneDecksing
About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.695911
(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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ENSEMBL Gene Tree for GAGE2E
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for GAGE2E gene
GAGE2D1 2  GAGE2C1 2  GAGE2B1 2  GAGE131 2  GAGE2A1 2  GAGE12I1  GAGE12G1 2  GAGE12F1 2  
GAGE11 2  GAGE12J1 2  GAGE12D1  GAGE12C1 2  GAGE12E1 2  GAGE12H1 2  XAGE32  GAGE102  
ENSG000001691642  XAGE52  XAGE2B2  PAGE12  XAGE22  

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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1 NCBI SNPs in GAGE2E are shown
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr X posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
------------
--
rs40755441,2
--49086426(+) tgtgtG/TAGGCA 1 -- int10--------
About this table

HapMap Linkage Disequilibrium images for GAGE2E (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 300736

(Possibly Related Articles in Doctor's Guide)
About This Section

  --

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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7 PubMed articles for GAGE2E gene:
(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 26749 HGNC: 31960 AceView: GAGE2 Ensembl:ENSG00000222023 euGenes: HUgn26749
ECgene: GAGE2E H-InvDB: GAGE2E
(According to HUGE)
About This Section

  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

  --
(Available from WIS Yeda, Salk, Tufts)
About This Section

  --
(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for GAGE2E:
 TaqMan ® Gene Expression Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
  Invitrogen Clones  Invitrogen Q-PCR Products
  Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for GAGE2E-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for GAGE2E Browse antibodies at Sigma-Aldrich
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for GAGE2E Browse small molecules at Sigma-Aldrich
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 Search Novus for antibodies for GAGE2E

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