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Aliases &
Descriptions
for GAGE2C
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| AL4 3 | | CT4.2 2, 3 | | CT4.3 3 | | CT4.5 3 | | CT4.6 3 | | CT4.7 3 | | GAGE-2 3 | | GAGE-3 3 | | GAGE-5 3 | | GAGE-6 3 | | GAGE-7 3 | | GAGE-7B 3 | | GAGE-8 3 | | GAGE2 2, 3, 5 | | GAGE7 3 | | MGC120097 2 | | MGC96883 2 | | MGC96930 2 | | MGC96942 2 | | OTTHUMP00000070309 2 |
| | | Descriptions |
|---|
| Cancer/testis antigen 4.2 2, 3 | | Cancer/testis antigen 4.3 3 | | Cancer/testis antigen 4.5 3 | | Cancer/testis antigen 4.6 3 | | Cancer/testis antigen 4.7 3 | | G antigen 2 2 | | G antigen 2C 2 |
|
| |
Search outside databases for aliases for GAGE2C genePrevious GC identifers: GC0XU900879 GC0XP049118 |
Summaries
for GAGE2C(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for GAGE2C:
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal
tissues, except for the testis. The sequences of the family members are highly related but differ
by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by
several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by
RefSeq]
UniProtKB/Swiss-Prot: GAGE2_HUMAN, Q13066Function: Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes |
Genomic Location
for GAGE2C
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.23 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.23GAGE2C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP049090:
(about GC identifiers)
Start:
|
49,084,570 bp from pter |
End:
|
49,120,435 bp from pter |
Size:
|
35,866 bases |
Orientation:
|
plus strand |
| Proteins
for GAGE2C
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: GAGE5_HUMAN, Q13069 (See
protein sequence)Recommended Name: G antigen 5 Size: 117 amino acids; 12924 Da
Secondary accessions: Q6FG72UniProtKB/Swiss-Prot: GAGE3_HUMAN, Q13067 (See
protein sequence)Recommended Name: G antigen 3 Size: 118 amino acids; 12937 DaUniProtKB/Swiss-Prot: GAGE7_HUMAN, O76087 (See
protein sequence)Recommended Name: G antigen 7 Size: 117 amino acids; 12978 Da
Secondary accessions: Q4V324UniProtKB/Swiss-Prot: GAGE2_HUMAN, Q13066 (See
protein sequence)Recommended Name: G antigen 2A/2B Size: 116 amino acids; 12786 Da
Secondary accessions: Q4V322UniProtKB/Swiss-Prot: GAGE6_HUMAN, Q13070 (See
protein sequence)Recommended Name: G antigen 6 Size: 117 amino acids; 12892 DaPost-translational modifications:
View phosphorylation sites using PhosphoSite2 (GAGE5)
REFSEQ proteins: NP_001463.1
ENSEMBL proteins: ENSP00000371136 ENSP00000371127 ENSP00000371124 ENSP00000371123 ENSP00000386110 ENSP00000384742 ENSP00000365346
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for GAGE2C:
Assays for GAGE2C: | Protein
Domains/
Families
for GAGE2C(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q13069
- Graphical View of Domain Structure for InterPro Entry Q13067
- Graphical View of Domain Structure for InterPro Entry O76087
- Graphical View of Domain Structure for InterPro Entry Q13066
- Graphical View of Domain Structure for InterPro Entry Q13070
ProtoNet protein and cluster: Q13069 1 Blocks protein family: IPB008625 GAGE
UniProtKB/Swiss-Prot: GAGE5_HUMAN, Q13069Similarity: Belongs to the GAGE familyUniProtKB/Swiss-Prot: GAGE3_HUMAN, Q13067Similarity: Belongs to the GAGE familyUniProtKB/Swiss-Prot: GAGE7_HUMAN, O76087Similarity: Belongs to the GAGE familyUniProtKB/Swiss-Prot: GAGE2_HUMAN, Q13066Similarity: Belongs to the GAGE familyUniProtKB/Swiss-Prot: GAGE6_HUMAN, Q13070Similarity: Belongs to the GAGE family | Gene Function
for GAGE2C
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001472
 Applied Biosystems Silencer® siRNAs for GAGE2C
 Sigma-Aldrich siRNA for GAGE2C
Sigma-Aldrich shRNA for GAGE2C
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001472
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001472
untagged cDNA clone in CMV expression vector: NM_001472
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_001472
UniProtKB/Swiss-Prot: GAGE2_HUMAN, Q13066Function: Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes | Pathways & Interactions
for GAGE2C
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
1 Interacting protein for GAGE2C (Q130692) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds
for GAGE2C(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for GAGE2C
|
Transcripts
for GAGE2C(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001472
Sigma-Aldrich siRNA for GAGE2C
Sigma-Aldrich shRNA for GAGE2C
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_001472 REFSEQ mRNAs for GAGE2C gene: NM_001472.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001472
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001472
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001472
untagged cDNA clone in CMV expression vector: NM_001472
24/29 AceView cDNA sequences (see all 29
):BC024914 U19145 NM_001474 BM832793 BC069309 NM_012196 U19143 BX108227 BC005363 AF055473 BM836228 AW016546 AA447559 BX283580 CF780547 BC018052 AW510753 NM_001472 BG208433 AW102587 BG206349 BG120838 BP431265 AA738037
GeneLoc Exon Structure
7 Ensembl transcripts including schematic representations: ENST00000381717
ENST00000381708
ENST00000381705
ENST00000381704
ENST00000404720
ENST00000402590
ENST00000376176
|
Expression
for GAGE2C
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| GAGE2C expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for GAGE2C
1 / 2 15 probe-sets matching GAGE2C gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
UniProtKB/Swiss-Prot: GAGE5_HUMAN, Q13069Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except
testisUniProtKB/Swiss-Prot: GAGE3_HUMAN, Q13067Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except
testisUniProtKB/Swiss-Prot: GAGE7_HUMAN, O76087Tissue specificity: Expressed in some prostate cancer tissues but not in normal prostate tissueUniProtKB/Swiss-Prot: GAGE2_HUMAN, Q13066Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except
testisUniProtKB/Swiss-Prot: GAGE6_HUMAN, Q13070Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except
testis |
Orthologs
for GAGE2C
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for GAGE2C | Paralogs
for GAGE2C(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for GAGE2C gene
- GAGE2B1 2 GAGE2D1 2 GAGE2E1 2 GAGE2A1 2 GAGE12I1 GAGE12G1 2 GAGE12F1 2 GAGE131 2
- GAGE12D1 GAGE12C1 2 GAGE12E1 2 GAGE12H1 2 GAGE11 2 GAGE12J1 2 XAGE32 GAGE102
- ENSG000001691642 XAGE52 XAGE2B2 PAGE12 XAGE22
|
SNPs/Variants
for GAGE2C(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for GAGE2C (up to first 250kb)
|
Disorders & Mutations
for GAGE2C
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 300595
|
Medical News
for GAGE2C(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for GAGE2C (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 9 PubMed articles for GAGE2C gene: |
Search for GAGE2C
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing GAGE2C
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing GAGE2C
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GAGE2C(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for GAGE2C(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for GAGE2C:
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