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Aliases for GAGE2B Gene

Aliases for GAGE2B Gene

  • G Antigen 2B 2 3
  • Cancer/Testis Antigen 4.2 3 4
  • GAGE-2B 3 4
  • CT4.2 3 4
  • G Antigen 2A/2B 3
  • G Antigen 13 5
  • G Antigen 2C 4
  • GAGE-2C 4
  • GAGE-2 3
  • GAGE13 5
  • GAGE2 4

External Ids for GAGE2B Gene

Previous GeneCards Identifiers for GAGE2B Gene

  • GC0XU900862
  • GC0XP049123
  • GC0XP049124
  • GC0XP049235
  • GC0XP049234

Summaries for GAGE2B Gene

GeneCards Summary for GAGE2B Gene

GAGE2B (G Antigen 2B) is a Protein Coding gene. An important paralog of this gene is XAGE5.

UniProtKB/Swiss-Prot for GAGE2B Gene

  • Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE2B Gene

Genomics for GAGE2B Gene

Regulatory Elements for GAGE2B Gene

Enhancers for GAGE2B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GAGE2B on UCSC Golden Path with GeneCards custom track

Genomic Location for GAGE2B Gene

49,331,615 bp from pter
49,338,952 bp from pter
7,338 bases
Plus strand

Genomic View for GAGE2B Gene

Genes around GAGE2B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GAGE2B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GAGE2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GAGE2B Gene

Proteins for GAGE2B Gene

  • Protein details for GAGE2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    G antigen 2B/2C
    Protein Accession:
    Secondary Accessions:
    • C9K0W9
    • Q4V322

    Protein attributes for GAGE2B Gene

    116 amino acids
    Molecular mass:
    12786 Da
    Quaternary structure:
    No Data Available
    • This gene belongs to a family of genes organized in clustered repeats. They have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.

neXtProt entry for GAGE2B Gene

Proteomics data for GAGE2B Gene at MOPED

Post-translational modifications for GAGE2B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE2B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GAGE2B Gene

Domains & Families for GAGE2B Gene

Protein Domains for GAGE2B Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the GAGE family.
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE2B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for GAGE2B Gene

Function for GAGE2B Gene

Molecular function for GAGE2B Gene

UniProtKB/Swiss-Prot Function:
Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes.

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GAGE2B Gene

Localization for GAGE2B Gene

Subcellular locations from

Jensen Localization Image for GAGE2B Gene COMPARTMENTS Subcellular localization image for GAGE2B gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for GAGE2B Gene

Pathways & Interactions for GAGE2B Gene

SuperPathways for GAGE2B Gene

No Data Available

Interacting Proteins for GAGE2B Gene

Gene Ontology (GO) - Biological Process for GAGE2B Gene


No data available for Pathways by source and SIGNOR curated interactions for GAGE2B Gene

Drugs & Compounds for GAGE2B Gene

No Compound Related Data Available

Transcripts for GAGE2B Gene

mRNA/cDNA for GAGE2B Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE2B Gene

No ASD Table

Relevant External Links for GAGE2B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GAGE2B Gene

mRNA expression in normal human tissues for GAGE2B Gene

mRNA differential expression in normal tissues according to GTEx for GAGE2B Gene

This gene is overexpressed in Testis (x53.0).

SOURCE GeneReport for Unigene cluster for GAGE2B Gene Hs.714681

mRNA Expression by UniProt/SwissProt for GAGE2B Gene

Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except testis.
genes like me logo Genes that share expression patterns with GAGE2B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for GAGE2B Gene

Orthologs for GAGE2B Gene

Evolution for GAGE2B Gene

Gene Tree for GAGE2B (if available)
Gene Tree for GAGE2B (if available)

No data available for Orthologs for GAGE2B Gene

Paralogs for GAGE2B Gene

genes like me logo Genes that share paralogs with GAGE2B: view

Variants for GAGE2B Gene

Structural Variations from Database of Genomic Variants (DGV) for GAGE2B Gene

Variant ID Type Subtype PubMed ID
esv24944 CNV Gain+Loss 19812545
nsv821250 CNV Deletion 20802225

Variation tolerance for GAGE2B Gene

Gene Damage Index Score: 0.00; 0.11% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for GAGE2B Gene

Disorders for GAGE2B Gene

Relevant External Links for GAGE2B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for GAGE2B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAGE2B Gene

Publications for GAGE2B Gene

  1. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff M.F. … Ditzel H.J. (Tissue Antigens 2008) 3 4 67
  2. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. (PMID: 7544395) van den Eynde B. … Boon T. (J. Exp. Med. 1995) 3

Products for GAGE2B Gene

Sources for GAGE2B Gene