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Aliases for GAGE2B Gene

Aliases for GAGE2B Gene

  • G Antigen 2B 2 3
  • Cancer/Testis Antigen 4.2 3 4
  • GAGE-2B 3 4
  • CT4.2 3 4
  • G Antigen 2A/2B 3
  • GAGE2B GAGE2C 4
  • G Antigen 2C 4
  • GAGE-2C 4
  • GAGE-2 3
  • GAGE2 4

External Ids for GAGE2B Gene

Previous GeneCards Identifiers for GAGE2B Gene

  • GC0XU900862
  • GC0XP049123
  • GC0XP049124
  • GC0XP049235
  • GC0XP049234

Summaries for GAGE2B Gene

GeneCards Summary for GAGE2B Gene

GAGE2B (G Antigen 2B) is a Protein Coding gene.

UniProtKB/Swiss-Prot for GAGE2B Gene

  • Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE2B Gene

Genomics for GAGE2B Gene

Genomic Location for GAGE2B Gene

Chromosome:
X
Start:
49,331,615 bp from pter
End:
49,338,952 bp from pter
Size:
7,338 bases
Orientation:
Plus strand

Genomic View for GAGE2B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GAGE2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GAGE2B Gene

No data available for Regulatory Elements for GAGE2B Gene

Proteins for GAGE2B Gene

  • Protein details for GAGE2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13066-GAG2B_HUMAN
    Recommended name:
    G antigen 2B/2C
    Protein Accession:
    Q13066
    Secondary Accessions:
    • C9K0W9
    • Q4V322

    Protein attributes for GAGE2B Gene

    Size:
    116 amino acids
    Molecular mass:
    12786 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene belongs to a family of genes organized in clustered repeats. They have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells

neXtProt entry for GAGE2B Gene

Proteomics data for GAGE2B Gene at MOPED

Post-translational modifications for GAGE2B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE2B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GAGE2B Gene

Domains & Families for GAGE2B Gene

Protein Domains for GAGE2B Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q13066

UniProtKB/Swiss-Prot:

GAG2B_HUMAN :
  • Belongs to the GAGE family.
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE2B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for GAGE2B Gene

Function for GAGE2B Gene

Molecular function for GAGE2B Gene

UniProtKB/Swiss-Prot Function:
Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes

Gene Ontology (GO) - Molecular Function for GAGE2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with GAGE2B: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GAGE2B

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GAGE2B Gene

Localization for GAGE2B Gene

Gene Ontology (GO) - Cellular Components for GAGE2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with GAGE2B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for GAGE2B Gene

Pathways & Interactions for GAGE2B Gene

SuperPathways for GAGE2B Gene

No Data Available

Interacting Proteins for GAGE2B Gene

Gene Ontology (GO) - Biological Process for GAGE2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with GAGE2B: view

No data available for Pathways by source and SIGNOR curated interactions for GAGE2B Gene

Drugs & Compounds for GAGE2B Gene

No Compound Related Data Available

Transcripts for GAGE2B Gene

mRNA/cDNA for GAGE2B Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GAGE2B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE2B Gene

No ASD Table

Relevant External Links for GAGE2B Gene

GeneLoc Exon Structure for
GAGE2B
ECgene alternative splicing isoforms for
GAGE2B

Expression for GAGE2B Gene

mRNA expression in normal human tissues for GAGE2B Gene

mRNA differential expression in normal tissues according to GTEx for GAGE2B Gene

This gene is overexpressed in Testis (x53.0).

SOURCE GeneReport for Unigene cluster for GAGE2B Gene Hs.714681

mRNA Expression by UniProt/SwissProt for GAGE2B Gene

Q13066-GAG2B_HUMAN
Tissue specificity: Expressed in a variety of tumor tissues but not in normal tissues, except testis.
genes like me logo Genes that share expression patterns with GAGE2B: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for GAGE2B Gene

Orthologs for GAGE2B Gene

Evolution for GAGE2B Gene

ENSEMBL:
Gene Tree for GAGE2B (if available)
TreeFam:
Gene Tree for GAGE2B (if available)

No data available for Orthologs for GAGE2B Gene

Paralogs for GAGE2B Gene

genes like me logo Genes that share paralogs with GAGE2B: view

No data available for Paralogs for GAGE2B Gene

Variants for GAGE2B Gene

Structural Variations from Database of Genomic Variants (DGV) for GAGE2B Gene

Variant ID Type Subtype PubMed ID
esv24944 CNV Gain+Loss 19812545
nsv821250 CNV Deletion 20802225

Variation tolerance for GAGE2B Gene

Gene Damage Index Score: 0.00; 0.11% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GAGE2B Gene

HapMap Linkage Disequilibrium report
GAGE2B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for GAGE2B Gene

Disorders for GAGE2B Gene

Relevant External Links for GAGE2B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GAGE2B
genes like me logo Genes that share disorders with GAGE2B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAGE2B Gene

Publications for GAGE2B Gene

  1. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff M.F. … Ditzel H.J. (Tissue Antigens 2008) 67
  2. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 67
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. (PMID: 7544395) van den Eynde B. … Boon T. (J. Exp. Med. 1995) 67

Products for GAGE2B Gene

Sources for GAGE2B Gene

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