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GAGE13 Gene

protein-coding GIFtS: 29

GC0XP049073

G antigen 13
(Previous name: G antigen 12A )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: GAGE12A)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
GAGE-12A ^³
GAGE12A ^², ³
MGC163246 ^²
OTTHUMG00000024138 ^¹
OTTHUMP00000025836 ^²

Descriptions
G antigen 12A ^¹, ², ³
G antigen 13 ^²

External Ids
HGNC: 29081¹
Entrez Gene: 645051²
UniProtKB: Q4V321³
Ensembl: ENSG00000215269⁷

Search outside databases for aliases for GAGE13 gene

Previous GC identifer: GC0XP049076

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.23

GAGE13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XP049073: (about GC identifiers)

Start:	49,047,069 bp from pter
End:	49,082,313 bp from pter
Size:	35,245 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000023.9 NT_079573.3

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: GAG13_HUMAN, Q4V321 (See protein sequence)

Recommended Name: G antigen 13

Size: 117 amino acids; 12873 Da

REFSEQ proteins: NP_001091882.1

ENSEMBL proteins:

ENSP00000371170 ENSP00000384542

Human Recombinant Proteins

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	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

Antibodies for GAGE13:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for GAGE13

Assays for GAGE13:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q4V321

ProtoNet protein and cluster: Q4V321

1 Blocks protein family: IPB008625 GAGE

UniProtKB/Swiss-Prot: GAG13_HUMAN, Q4V321

Similarity: Belongs to the GAGE family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Browse Invitrogen for RNAi
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

Browse Origene for 29mer shRNA kit in GFP-retroviral vector

Applied Biosystems Silencer® siRNAs for GAGE13

Sigma-Aldrich siRNA for GAGE13

Browse shRNA at Sigma-Aldrich

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001085441
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001085441
untagged cDNA clones in CMV expression vector (see all 2): NM_001085441

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001098412

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for GAGE13

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
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Inhib. RNA:		Browse Invitrogen for RNAi
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

Browse Origene for 29mer shRNA kit in GFP-retroviral vector

Sigma-Aldrich siRNA for GAGE13

Browse shRNA at Sigma-Aldrich

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001098412

REFSEQ mRNAs for GAGE13 gene:

NM_001098412.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001098412

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001085441
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001085441
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001085441

Additional cDNA sequence: AK310423.1

Unigene Cluster for GAGE13:

G antigen 13

Hs.695912

Unigene Representative Sequence: AK310423

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000381751 ENST00000404804

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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GAGE13 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for GAGE13

¹ / ²

11 probe-sets matching GAGE13 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33671_f_at²	U95-A	24	1.00	0.04	0.86	0.60	--	--	--	--	--
33680_f_at²	U95-A	24	1.00	0.04	0.50	0.55	--	--	--	--	--
31497_at²	U95-A	23	0.94	0.09	0.39	2.10	--	--	--	--	--
37065_f_at²	U95-A	24	0.94	0.04	0.61	0.88	--	--	--	--	--
31498_f_at²	U95-A	24	0.94	0.04	0.73	0.92	--	--	--	--	--
31960_f_at²	U95-A	24	0.94	0.04	0.72	0.66	--	--	--	--	--
31954_f_at²	U95-A	23	0.94	0.04	0.62	0.32	--	--	--	--	--
207739_s_at²	U133-A	23	0.91	0.04	--	--	--	--	--	--	--
207086_x_at²	U133-A	23	0.82	0.04	--	--	--	--	--	--	--
207739_s_at²	U133Plus2	23	0.91	0.04	--	--	--	--	--	--	--
207086_x_at²	U133Plus2	23	0.82	0.04	--	--	--	--	--	--	--

GeneDecks GAGE13 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.695912

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

ENSEMBL Gene Tree for GAGE13

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for GAGE13 gene

GAGE2D¹ ² GAGE2E¹ ² GAGE2C¹ ² GAGE2B¹ ² GAGE12J¹ ² GAGE12D¹ GAGE12C¹ ² GAGE12E¹ ²

GAGE2A¹ ² GAGE12I¹ GAGE12G¹ ² GAGE12H¹ ² GAGE12F¹ ² GAGE1¹ ² XAGE3² GAGE10²

ENSG00000169164² XAGE5² XAGE2B² PAGE1² XAGE2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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8 NCBI SNPs in GAGE13 are shown

AB	SNP ID	Valid	Chr X pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs6651686^1,2	--	49073854(+)	`TGTACA/GTTTTT`	1	--	ng5¹		0	--	--	--	--
--	rs5902446^1,2	--	49074040(+)	`gatgg-/Tttttt`	1	--	ng5¹		0	--	--	--	--
--	rs72224546^1,2	--	49076898(+)	`TGCAC-/TGTG GTGTG`	1	--	ut3¹		0	--	--	--	--
--	rs59480147^1,2	--	49073661(+)	`ATTTCA/GCCATC`	1	--	ng5¹		0	--	--	--	--
--	rs6609895^1,2	--	49073866(+)	`GGTTCA/GATTAT`	1	--	ng5¹		0	--	--	--	--
--	rs6609894^1,2	--	49073819(+)	`TCATGG/TGTTAA`	1	--	ng5¹		0	--	--	--	--
--	rs28734486^1,2	--	49076142(+)	`GTTGTC/GTGTTT`	1	--	int¹		0	--	--	--	--
--	rs6609900^1,2	--	49076360(+)	`AATGAG/TGATGG`	1	--	int¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for GAGE13 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 300734

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

4 PubMed articles for GAGE13 gene:

The DNA sequence of the human X chromosome. (PubMed id 15772651)^{3, 4} Ross M.T.... Bentley D.R. (2005)
An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PubMed id 18179644)³ Gjerstorff M.F. and Ditzel H.J. (2008)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Creation of genome-wide protein expression libraries using random activation of gene expression. (PubMed id 11329013)³ Harrington J.J....Ducar M. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 645051	HGNC: 29081	Ensembl:ENSG00000215269	euGenes: HUgn645051	ECgene: GAGE13
H-InvDB: GAGE13

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for GAGE13
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for GAGE13:

TaqMan ® Gene Expression Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for GAGE13-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for GAGE13		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Browse shRNAs at Sigma-Aldrich		Browse small molecules at Sigma-Aldrich
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	Recombinant & Natural Proteins

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Search Novus for antibodies for GAGE13

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GAGE13 Gene

protein-coding GIFtS: 29

Aliases &
Descriptions
for GAGE13

Summaries
for GAGE13

Genomic Location
for GAGE13

Proteins
for GAGE13

Protein Domains/
Families
for GAGE13

Gene Function
for GAGE13

Pathways & Interactions
for GAGE13

Drugs & Compounds
for GAGE13

Transcripts
for GAGE13

Expression
for GAGE13

Orthologs
for GAGE13

Paralogs
for GAGE13

SNPs/Variants
for GAGE13

Disorders & Mutations
for GAGE13

Medical News
for GAGE13

Publications
for GAGE13

Search for GAGE13

Genome Databases showing GAGE13

Other Databases showing GAGE13

Specialized Databases showing GAGE13

Licensable Technologies
for GAGE13

Services
for GAGE13

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GAGE13 Gene

protein-coding GIFtS: 29

Aliases & Descriptionsfor GAGE13

Summariesfor GAGE13

Genomic Locationfor GAGE13

Proteinsfor GAGE13

Protein Domains/Familiesfor GAGE13

Gene Functionfor GAGE13

Pathways & Interactionsfor GAGE13

Drugs & Compoundsfor GAGE13

Transcriptsfor GAGE13

Expression for GAGE13

Orthologsfor GAGE13

Paralogsfor GAGE13

SNPs/Variantsfor GAGE13

Disorders & Mutationsfor GAGE13

Medical Newsfor GAGE13

Publicationsfor GAGE13

Search for GAGE13

Genome Databases showing GAGE13

Other Databases showing GAGE13

Specialized Databases showing GAGE13

Licensable Technologiesfor GAGE13

Servicesfor GAGE13

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for GAGE13

Summaries
for GAGE13

Genomic Location
for GAGE13

Proteins
for GAGE13

Protein Domains/
Families
for GAGE13

Gene Function
for GAGE13

Pathways & Interactions
for GAGE13

Drugs & Compounds
for GAGE13

Transcripts
for GAGE13

Expression
for GAGE13

Orthologs
for GAGE13

Paralogs
for GAGE13

SNPs/Variants
for GAGE13

Disorders & Mutations
for GAGE13

Medical News
for GAGE13

Publications
for GAGE13

Licensable Technologies
for GAGE13

Services
for GAGE13