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Aliases for GAGE12J Gene

Aliases for GAGE12J Gene

  • G Antigen 12J 2 3 5
  • G Antigen 11 2 3
  • GAGE-12J 4
  • GAGE11 3

External Ids for GAGE12J Gene

Previous HGNC Symbols for GAGE12J Gene

  • GAGE11

Previous GeneCards Identifiers for GAGE12J Gene

  • GC0XP049071
  • GC0XP049072
  • GC0XP049074
  • GC0XP049180
  • GC0XP049181
  • GC0XP049182

Summaries for GAGE12J Gene

GeneCards Summary for GAGE12J Gene

GAGE12J (G Antigen 12J) is a Protein Coding gene. An important paralog of this gene is XAGE5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE12J Gene

Genomics for GAGE12J Gene

Regulatory Elements for GAGE12J Gene

Enhancers for GAGE12J Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GAGE12J on UCSC Golden Path with GeneCards custom track

Genomic Location for GAGE12J Gene

49,322,030 bp from pter
49,329,387 bp from pter
7,358 bases
Plus strand

Genomic View for GAGE12J Gene

Genes around GAGE12J on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GAGE12J Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GAGE12J Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GAGE12J Gene

Proteins for GAGE12J Gene

  • Protein details for GAGE12J Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    G antigen 12J
    Protein Accession:

    Protein attributes for GAGE12J Gene

    117 amino acids
    Molecular mass:
    12896 Da
    Quaternary structure:
    No Data Available
    • This gene belongs to a multigene family expressed in a large variety of tumors whereas in normal tissues, expression is restricted to germ cells. These genes organized in clustered repeats, have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.

neXtProt entry for GAGE12J Gene

Proteomics data for GAGE12J Gene at MOPED

Post-translational modifications for GAGE12J Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE12J Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GAGE12J Gene

Domains & Families for GAGE12J Gene

Protein Domains for GAGE12J Gene


Suggested Antigen Peptide Sequences for GAGE12J Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the GAGE family.
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE12J: view

No data available for Gene Families for GAGE12J Gene

Function for GAGE12J Gene

Phenotypes for GAGE12J Gene

GenomeRNAi human phenotypes for GAGE12J:
genes like me logo Genes that share phenotypes with GAGE12J: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GAGE12J Gene

Localization for GAGE12J Gene

Subcellular locations from

Jensen Localization Image for GAGE12J Gene COMPARTMENTS Subcellular localization image for GAGE12J gene
Compartment Confidence
extracellular 2
cytosol 1
mitochondrion 1
nucleus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for GAGE12J Gene

Pathways & Interactions for GAGE12J Gene

SuperPathways for GAGE12J Gene

No Data Available

Interacting Proteins for GAGE12J Gene

Gene Ontology (GO) - Biological Process for GAGE12J Gene


No data available for Pathways by source and SIGNOR curated interactions for GAGE12J Gene

Drugs & Compounds for GAGE12J Gene

No Compound Related Data Available

Transcripts for GAGE12J Gene

mRNA/cDNA for GAGE12J Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE12J Gene

No ASD Table

Relevant External Links for GAGE12J Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GAGE12J Gene

mRNA expression in normal human tissues for GAGE12J Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GAGE12J Gene

This gene is overexpressed in Testis (x50.6).
genes like me logo Genes that share expression patterns with GAGE12J: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for GAGE12J Gene

Orthologs for GAGE12J Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for GAGE12J Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 93 (a)
Species with no ortholog for GAGE12J:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for GAGE12J Gene

Gene Tree for GAGE12J (if available)
Gene Tree for GAGE12J (if available)

Paralogs for GAGE12J Gene

genes like me logo Genes that share paralogs with GAGE12J: view

Variants for GAGE12J Gene

Sequence variations from dbSNP and Humsavar for GAGE12J Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs7064096 - 49,323,219(+) GACCT(A/G)TTATT reference, missense
rs7064105 - 49,323,232(+) CCTAG(A/T)CCAAG reference, missense
rs6520418 - 49,323,240(+) AAGAC(C/G/T)CTATG reference, missense
rs7064530 - 49,323,276(+) TATGC(A/G/T)GGTGA reference, missense
rs1137130 -- 49,326,707(+) AAGCT(C/G)ATAGC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for GAGE12J Gene

Variant ID Type Subtype PubMed ID
esv24944 CNV Gain+Loss 19812545
nsv821250 CNV Deletion 20802225
nsv6896 CNV Insertion 18451855
nsv515201 CNV Complex 21397061
nsv6897 CNV Insertion 18451855

Variation tolerance for GAGE12J Gene

Gene Damage Index Score: 4.72; 66.27% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for GAGE12J Gene

Disorders for GAGE12J Gene

Relevant External Links for GAGE12J

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for GAGE12J Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAGE12J Gene

Publications for GAGE12J Gene

  1. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff M.F. … Ditzel H.J. (Tissue Antigens 2008) 3 4 67
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for GAGE12J Gene

Sources for GAGE12J Gene