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GAGE10 Gene

protein-coding   GIFtS: 29

GC0XP049064
G antigen 10
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
GAGE-10 3
OTTHUMG00000024136 1
OTTHUMP00000025834 2
Descriptions
G antigen 10 2
External Ids
HGNC: 309681
Entrez Gene: 6438322
UniProtKB: A6NGK33
Ensembl: ENSG000002152767
Search outside databases for aliases for GAGE10 gene

Previous GC identifers: GC0XP049048 GC0XP049063

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the GAGE10 gene  

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.23

GAGE10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP049064:     (about GC identifiers)

Start:
49,047,069 bp from pter
End:
49,063,267 bp from pter
Size:
16,199 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000023.9  NT_079573.3  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: GAG10_HUMAN, A6NGK3 (See protein sequence)
Recommended Name: G antigen 10  
Size: 116 amino acids; 12651 Da

REFSEQ proteins: NP_001091883.2  

ENSEMBL proteins: 
ENSP00000371173 


Human Recombinant Proteins 
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Browse recombinant and purified proteins available from Enzo Life Sciences
Browse Abcam for Recombinant Proteins
Browse Abnova for Human Recombinant Proteins
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 


Antibodies for GAGE10: 
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Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
Browse Abnova for Monoclonal and Polyclonal Antibodies
Search Novus for antibodies for GAGE10

Assays for GAGE10: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro domain/family:
 IPR008625 GAGE


   GeneDecks  GAGE10 for the domains selected above  
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Graphical View of Domain Structure for InterPro Entry A6NGK3

ProtoNet protein and cluster: A6NGK3

UniProtKB/Swiss-Prot: GAG10_HUMAN, A6NGK3
Similarity: Belongs to the GAGE family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib.
RNA:
Browse Invitrogen for RNAi
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
                Browse Origene for 29mer shRNA kit in GFP-retroviral vector

              Applied Biosystems Silencer® siRNAs for GAGE10

              Sigma-Aldrich siRNA for GAGE10  
                     Browse shRNA at Sigma-Aldrich  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Browse Clone Ranger at Invitrogen for clones
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001098413
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001098413
                                 untagged cDNA clone in CMV expression vector: NM_001098413 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_001098413

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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  --
(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for GAGE10

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene)
About This Section

Inhib.
RNA:
Browse Invitrogen for RNAi
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
                Browse Origene for 29mer shRNA kit in GFP-retroviral vector

              Sigma-Aldrich siRNA for GAGE10  
                     Browse shRNA at Sigma-Aldrich  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_001098413  

REFSEQ mRNAs for GAGE10 gene: 

NM_001098413.2   


              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001098413
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001098413
                                 untagged cDNA clone in CMV expression vector: NM_001098413 

2 DOTS entries:

DT.121292581  DT.444944 

highest scoring ESTs for GAGE10:

DA632906 EC467116 EC484193 EC505040 EC533899 EC539284 EC557515 EC557769 EC562237 EC582890 

Unigene Cluster for GAGE10:

G antigen 10
Hs.562044  [show with all ESTs]
Unigene Representative Sequence: NM_001098413


GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:
ENST00000381754  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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GAGE10 expression in normal and diseased human tissues

1 / 3Data from (Publications) and GNF BioGPS
    About these images

About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.562044
(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for GAGE10 gene from 1 species
Organism Gene Locus Description Human
Similarity
NCBI accessions
chimpanzee
(Pan troglodytes)
GAGE101   -- G antigen 10 97.08(n)
92.11(a)
741048  XM_001143398.1  XP_001143398.1 
About this table        Species with no ortholog for GAGE10

ENSEMBL Gene Tree for GAGE10
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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Paralogs for GAGE10 gene
XAGE32  GAGE2D2  GAGE12H2  ENSG000001691642  XAGE52  XAGE2B2  GAGE12C2  GAGE12E2  
GAGE2E2  GAGE12  GAGE2C2  GAGE12F2  GAGE132  PAGE12  XAGE22  GAGE12G2  
GAGE2B2  GAGE2A2  GAGE12J2  

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/121 NCBI SNPs in GAGE10 are shown (see all 121 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 10)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr X posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
------------
rs59525231,2
A,C,F,H49045690(+) gtcaaC/Tatcct 1 -- ng514Minor allele frequency- T:0.40EU EA WA 418
--
rs128491511,2
H49046087(+) atgtaA/Cccatt 1 -- ng514Minor allele frequency- C:0.00EU EA WA 416
--
rs59532861,2
A49046772(+) TTTTCC/GCAGGT 1 -- ng510--------
--
rs19846951,2
A,F,H,O49048611(+) AACACT/GGAGTA 1 -- int110Minor allele frequency- G:0.38NS EU EA WA MN 683
--
rs20154871,2
A,C,F,H49061048(+) ttacaT/Ggcgag 1 -- int14Minor allele frequency- G:0.38EU EA WA 412
rs48247551,2
A,C,F,H49051824(+) gagacT/Cggctc 1 -- int14Minor allele frequency- C:0.38EU EA WA 418
--
rs117984151,2
A,C,F,H49055204(+) gtagcT/Atactt 1 -- int14Minor allele frequency- A:0.38EU EA WA 420
--
rs59067821,2
A,C,F,H49060243(+) TATAAC/GAGTCT 1 -- int18Minor allele frequency- G:0.35EU EA WA 628
--
rs48244641,2
C,F,H49058775(+) aaggaT/Agtaga 1 -- int14Minor allele frequency- A:0.39EU EA WA 420
--
rs48247531,2
C,F,H49050864(+) ACTCAA/CATTTC 1 -- int112Minor allele frequency- C:0.13EU EA WA 836
About this table

HapMap Linkage Disequilibrium images for GAGE10 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 300737

(Possibly Related Articles in Doctor's Guide)
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  --

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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3 PubMed articles for GAGE10 gene:
(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 643832 HGNC: 30968 Ensembl:ENSG00000215276 euGenes: HUgn643832 ECgene: GAGE10
H-InvDB: GAGE10
(According to HUGE)
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  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

  --
(Available from WIS Yeda, Salk, Tufts)
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  --
(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for GAGE10:
 TaqMan ® Genotyping Assays
  Free SNP selection tool



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 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Browse shRNAs at Sigma-Aldrich Browse small molecules at Sigma-Aldrich
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 Search Novus for antibodies for GAGE10

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