Aliases for GAGE1 Gene
External Ids for GAGE1 Gene
Previous GeneCards Identifiers for GAGE1 Gene
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
GeneCards Summary for GAGE1 Gene
GAGE1 (G Antigen 1) is a Protein Coding gene. An important paralog of this gene is GAGE12F.
UniProtKB/Swiss-Prot for GAGE1 Gene
Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes. Completely silent in normal adult tissues, except testis.