Aliases for GABRR2 Gene
External Ids for GABRR2 Gene
Previous GeneCards Identifiers for GABRR2 Gene
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA receptor complex. [provided by RefSeq, Jul 2008]
GeneCards Summary for GABRR2 Gene
GABRR2 (Gamma-Aminobutyric Acid (GABA) A Receptor, Rho 2) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Circadian entrainment. GO annotations related to this gene include protein domain specific binding and extracellular ligand-gated ion channel activity. An important paralog of this gene is GABRR1.
UniProtKB/Swiss-Prot for GABRR2 Gene
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission
GABAC receptors are Cys-loop ionotropic ligand-gated ion channels mediating the fast synaptic inhibitory effects of GABA. Despite differing in physiology, biochemistry and pharmacology, GABAC receptors are viewed as a subclass of GABAA receptors.