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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GABRP Gene

protein-coding   GIFtS: 60
GCID: GC05P170143

gamma-aminobutyric acid (GABA) A receptor, pi

 Explore 11 diseases affiliated with
GABRP via our new
 Human Malady Compendium 
Biological research products
for GABRP
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Gamma-Aminobutyric Acid (GABA) A Receptor, Pi1 2
GABA(A) Receptor Subunit Pi2 3
GABA(A) Receptor, Pi2
Gamma-Aminobutyric Acid Receptor Subunit Pi2

External Ids:    HGNC: 40891   Entrez Gene: 25682   Ensembl: ENSG000000947557   OMIM: 6027295   UniProtKB: O005913   

Export aliases for GABRP gene to outside databases

Previous GC identifers: GC05P170445 GC05P170913 GC05P170146 GC05P170191 GC05P165308


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GABRP:
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory
synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several
non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits,
and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as
pregnanolone. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: GBRP_HUMAN, O00591
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding
to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the
receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor
subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone

summary for GABRP:
GABAA receptors are members of the cys-loop family of ligand-gated ion channels, responsible for mediating
the inhibitory effects of GABA alongside GABAB and GABAC receptors. They are pentameric proteins, consisting
of 5 subunits belonging to different families (alpha1-6, beta1-3, gamma1-3, delta, pi, epsilon, rho, theta).
The most abundant GABAA receptor in the mammalian brain consist of two copies each of alpha1 and beta2 with
a single gamma2 subunits. GABAA receptors contain an integral chloride channel, and have modulatory sites
for benzodiazepines, barbiturates, neurosteroids and ethanol.

Gene Wiki entry for GABRP


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_023133.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GABRP gene promoter:
         Max1   Sox5   RFX1   Evi-1   SRY   FOXJ2 (long isoform)   STAT3   FOXJ2   TGIF   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGABRP promoter sequence
   Search SABiosciences Chromatin IP Primers for GABRP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GABRP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.1   Ensembl cytogenetic band:  5q35.1   HGNC cytogenetic band: 5q35.1

GABRP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GABRP gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P170143:  view genomic region     (about GC identifiers)

Start:
170,190,354 bp from pter      End:
170,241,051 bp from pter
Size:
50,698 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GBRP_HUMAN, O00591 (See protein sequence)
Recommended Name: Gamma-aminobutyric acid receptor subunit pi precursor  
Size: 440 amino acids; 50640 Da
Subunit: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and epsilon.
A sixth class of subunit: Rho form homomeric GABA receptors that do not appear to coexist with GABA(A) receptor
subunits but with GABA(C) receptor subunits. Subunit Pi can also bind this complex
Subcellular location: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane;
Multi-pass membrane protein
Secondary accessions: A8KA36 D3DQL2 Q32MJ1

Explore the universe of human proteins at neXtProt for GABRP: NX_O00591

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O00591

  • GABRP Protein expression data from MOPED and PaxDb:    About this image 
    GABRP Protein Expression
    REFSEQ proteins: NP_055026.1  
    ENSEMBL proteins: 
     ENSP00000428804   ENSP00000428103   ENSP00000429668   ENSP00000430188   ENSP00000430100  
     ENSP00000429815   ENSP00000430727   ENSP00000430772   ENSP00000265294  

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    Browse Proteins at Uscn

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane ----
    GO:0030054cell junction IEA--
    GO:0034707chloride channel complex IEA--

    GABRP for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GABRP for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR018000 Neurotransmitter_ion_chnl_CS
     IPR006028 GABAA_rcpt
     IPR008100 GABAAp_rcpt
     IPR006201 Neur_channel
     IPR006202 Neur_chan_lig-bd

    Graphical View of Domain Structure for InterPro Entry O00591

    ProtoNet protein and cluster: O00591

    3 Blocks protein families:
    IPB006028 Gamma-aminobutyric acid A (GABAA) receptor signature
    IPB006201 Neurotransmitter-gated ion-channel
    IPB008100 Gamma-aminobutyric-acid A receptor pi subunit signature


    UniProtKB/Swiss-Prot: GBRP_HUMAN, O00591
    Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5)
    subfamily. GABRP sub-subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GBRP_HUMAN, O00591
    Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding
    to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the
    receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor
    subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity ----
    GO:0004890GABA-A receptor activity IEA--
    GO:0005230extracellular ligand-gated ion channel activity IEA--
    GO:0005254chloride channel activity IEA--
         
    GABRP for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for GABRP:
     Decreased POU5F1-GFP protein e 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Gabrp):
     normal 

    GABRP for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for GABRP 

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    hsa-miR-548am hsa-miR-125a-3p hsa-miR-27a hsa-miR-2110 hsa-miR-3918 hsa-miR-3150a-3p hsa-miR-617 hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmidGABRP 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GABRP


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Class A/1 (Rhodopsin-like receptors)
    Neuroactive ligand-receptor interaction0.38
    2GABA A receptor activation
    GABA signaling in brain0.26

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for GABRP
        GABA signaling in brain



    1         Kegg Pathway  (Kegg details for GABRP):
        Neuroactive ligand-receptor interaction


    GABRP for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GABRP

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport ----

    GABRP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for GABRP available from Tocris Bioscience    About this table
    CompoundAction CAS #
    MuscimolPotent GABAA agonist[2763-96-4]
    (+)-BicucullinePotent GABAA antagonist[485-49-4]
    IndiplonSubtype-selective GABAA receptor positive allosteric modulator[325715-02-4]
    L-655,708 Selective for alpha5-containing GABAA receptors[130477-52-0]
    SR 95531 hydrobromide Selective, competitive GABAA receptor antagonist [104104-50-9]

    2 HMDB Compounds for GABRP    About this table
    CompoundSynonyms CAS #PubMed Ids
    ChlorineCl2 (see all 13)16887-00-6--
    Gamma-Aminobutyric acid3-Carboxypropylamine (see all 27)56-12-2--

    10/22 DrugBank Compounds for GABRP (see all 22)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Lorazepam(+/-)-Lorazepam (see all 3)846-49-1targetpotentiator20138190 18384456 11752090
    Adinazolam-- 37115-32-5targetpotentiator6320036 6148400
    Chlordiazepoxide-- 58-25-3targetpotentiator18384456 11752090
    Clobazam-- 22316-47-8targetpotentiator18384456 11752090
    ClonazepamChlonazepam (see all 2)1622-61-3targetpotentiator18384456 11752090
    Clorazepate-- 23887-31-2targetpotentiator18384456 11752090
    Diazepam-- 439-14-5targetpotentiator18384456 11752090
    Estazolam-- 29975-16-4targetpotentiator639854 2889803
    Flurazepam-- 17617-23-1targetpotentiator18384456 11752090
    Halazepam-- 23092-17-3targetpotentiator2867566 6738302

    Search CenterWatch for drugs/clinical trials and news about GABRP / GBRP 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GABRP gene: 
    NM_014211.2  

    Unigene Cluster for GABRP:

    Gamma-aminobutyric acid (GABA) A receptor, pi
    Hs.26225  [show with all ESTs]
    Unigene Representative Sequence: NM_014211
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000521481 ENST00000521009 ENST00000519196 ENST00000522868 ENST00000518525
    ENST00000518122 ENST00000519385 ENST00000519598 ENST00000519137 ENST00000265294(uc003mau.3 uc011dev.2)


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    hsa-miR-548am hsa-miR-125a-3p hsa-miR-27a hsa-miR-2110 hsa-miR-3918 hsa-miR-3150a-3p hsa-miR-617 hsa-miR-548x
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    Additional cDNA sequence: 

    AK055205.1 AK292901.1 AK296805.1 AK300303.1 BC074810.2 BC074865.2 BC109105.1 BC109106.1 
    U95367.1 

    7 DOTS entries:

    DT.452502  DT.102831011  DT.120831620  DT.100034267  DT.102831012  DT.120831628  DT.75118728 

    24/96 AceView cDNA sequences (see all 96):

    AW439792 AU130953 AI560906 AW169065 AI521015 AI619885 CA312543 BX509618 
    AW438575 AI334802 BC074810 AI446810 AL708685 AI075074 BU679207 CR599634 
    AI912873 BC074865 AW372464 U95367 AL548209 CB852744 AA102670 BQ027740 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for GABRP    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
    SP1:                                                                              
    SP2:                                                                              
    SP3:                                                              -               


    ECgene alternative splicing isoforms for GABRP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GABRP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGCAGGAGCG
    GABRP Expression
    About this image
    See GABRP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GABRP

    SOURCE GeneReport for Unigene cluster: Hs.26225

    UniProtKB/Swiss-Prot: GBRP_HUMAN, O00591
    Tissue specificity: Most abundant in the uterus, also expressed in lung, thymus and prostate

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GABRP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for GABRP gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gabrp1 , 5 gamma-aminobutyric acid (GABA) A receptor, pi1, 5 88.86(n)1
    92.73(a)1
      11 (19.21 cM)5
    2166431  NM_146017.31  NP_666129.11 
     335507815 
    chicken
    (Gallus gallus)
    Aves GABRP1 gamma-aminobutyric acid (GABA) A receptor, pi 75.18(n)
    78.92(a)
      416174  XM_414507.3  XP_414507.2 
    lizard
    (Anolis carolinensis)
    Reptilia GABRP6
    --
    68(a)
    1 ↔ 1
    1(129874726-129898137)
    zebrafish
    (Danio rerio)
    Actinopterygii gabrp1 gamma-aminobutyric acid (GABA) A receptor, pi 60.46(n)
    60.05(a)
      566633  XM_002664433.1  XP_002664479.1 


    ENSEMBL Gene Tree for GABRP (if available)
    TreeFam Gene Tree for GABRP (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GABRP gene
    GLRA22  GABRR12  GLRB2  GLRA12  GABRB12  GABRD2  GLRA42  GABRB22  
    GABRQ2  GABRB32  GLRA32  GABRR22  
    18/24 SIMAP similar genes for GABRP using alignment to 8 protein entries:     GBRP_HUMAN (see all proteins) (see all similar genes):
    GABRD    GABRB3    GLRA3    GABRR1    GABRR2    GLRA4
    GABRB1    GABRR3    DKFZp781L0846    GABRB2    GLRA1    GABRA5
    GABRA3    GABRA2    GABRQ    GLRA2    GABRA6    GABRG1

    GABRP for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for GABRP
    PGOHUM00000239731


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/712 NCBI SNPs in GABRP are shown (see all 712    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1398002511,2
    C,Fother170235729(+) CTCTCG/AATTCA 2 /N /D mis11Minor allele frequency- A:0.00NA 4550
    rs1828278321,2
    --170208753(+) CCCCTC/TCCAGG 1 -- us2k10--------
    rs1856583001,2
    --170208835(+) GAGATA/GAGACG 1 -- us2k10--------
    rs77164701,2
    C,F,A--170208839(+) TAAGAT/CGCCTT 1 -- us2k114Minor allele frequency- C:0.32NA EA WA CSA 732
    rs1465696201,2
    --170208851(+) TCATAC/TCTACT 1 -- us2k10--------
    rs1900750021,2
    --170208895(+) GGGTAA/GTCAGT 1 -- us2k10--------
    rs1412227991,2
    --170208964(+) AAATAA/CTAACA 1 -- us2k10--------
    rs106437271,2
    C--170208994(+) CACAGGATA/-  
            
    GATAG
    1 -- us2k11Minor allele frequency- -:0.00CSA 2
    rs582259591,2
    C--170209000(+) ATAGATAGA/-  
            
    CAGAT
    1 -- us2k11Minor allele frequency- -:0.00NA 2
    rs2005986661,2
    C--170209001(+) ATAGAC/TAGATT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GABRP (170190354 - 170241051 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for GABRP: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GABRP for disorders           About GeneDecksing

    OMIM gene information: 602729    OMIM disorders: --

    11 diseases for GABRP:    About MalaCards
    anorexia nervosa    schizoaffective disorder    sporadic breast cancer    neuronitis
    bipolar disorder    breast cancer    schizophrenia    immunodeficiency
    adenocarcinoma    pancreatitis    prostatitis

    Genetic Association Database (GAD): GABRP
    Human Genome Epidemiology (HuGE) Navigator: GABRP (8 documents)

    Export disorders for GABRP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GABRP gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with GABRP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel class of GABAA receptor subunit in tissues of the reproductive system. (PubMed id 9182563)1, 2, 3 Hedblom E. and Kirkness E.F. (1997)
    2. Genetic investigation of chromosome 5q GABAA receptor subunit genes in schizophrenia. (PubMed id 16172613)1, 4 Petryshen T.L....Sklar P. (2005)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder. (PubMed id 20583128)1 Green E.K....Craddock N. (2010)
    6. Atypical behavioural effects of lorazepam: clues to t he design of novel therapies? (PubMed id 20138190)7 Giersch A....Vidailhet P. (2010)
    7. Association study of 182 candidate genes in anorexia nervosa. (PubMed id 20468064)1 Pinheiro A.P....Woodside D.B. (2010)
    8. HOXA10 regulates endometrial GABAA {pi} receptor expression and membrane translocation. (PubMed id 20103740)1 Sadeghi H. and Taylor H.S. (2010)
    9. Sequential use of transcriptional profiling, expressi on quantitative trait mapping, and gene association implicates MMP20 in human k idney aging. (PubMed id 19834535)1 Wheeler H.E....Kim S.K. (2009)
    10. Benzodiazepines in epilepsy: pharmacology and pharmac okinetics. (PubMed id 18384456)7 Riss J....Collins S. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2568 HGNC: 4089 AceView: GABRP Ensembl:ENSG00000094755 euGenes: HUgn2568
    ECgene: GABRP Kegg: 2568 H-InvDB: GABRP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GABRP Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for GABRP Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GABRP gene:
    Search GeneIP for patents involving GABRP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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