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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

GABRG1 Gene

protein-coding GIFtS: 57
GCID: GC04M045953

gamma-aminobutyric acid (GABA) A receptor, gamma 1

Explore 9 diseases affiliated with
GABRG1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Gamma-Aminobutyric Acid (GABA) A Receptor, Gamma 1¹ ²
GABA(A) Receptor Subunit Gamma-1² ³
GABA(A) Receptor, Gamma²
Gamma-1 Polypeptide²
Gamma-Aminobutyric Acid Receptor Subunit Gamma-1²

External Ids:	HGNC: 4086¹	Entrez Gene: 2565²	Ensembl: ENSG00000163285⁷	OMIM: 137166⁵	UniProtKB: Q8N1C3³

Export aliases for GABRG1 gene to outside databases

Previous GC identifers: GC04U990020 GC04M045892 GC04M045957 GC04M045878 GC04M045732 GC04M045360

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GABRG1:

The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein

and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an

integral chloride channel. This gene is clustered with three other family members on chromosome 4. (provided by

RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: GBRG1_HUMAN, Q8N1C3

Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding

to the GABA/benzodiazepine receptor and opening an integral chloride channel

summary for GABRG1:

GABAA receptors are members of the cys-loop family of ligand-gated ion channels, responsible for mediating

the inhibitory effects of GABA alongside GABAB and GABAC receptors. They are pentameric proteins, consisting

of 5 subunits belonging to different families (alpha1-6, beta1-3, gamma1-3, delta, pi, epsilon, rho, theta).

The most abundant GABAA receptor in the mammalian brain consist of two copies each of alpha1 and beta2 with

a single gamma2 subunits. GABAA receptors contain an integral chloride channel, and have modulatory sites

for benzodiazepines, barbiturates, neurosteroids and ethanol.

Gene Wiki entry for GABRG1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000004.11 NC_018915.1 NT_006238.11

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the GABRG1 gene promoter:
Olf-1 FOXO3 FOXO3b POU2F1 POU2F1a POU2F1b FOXO3a MRF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: GABRG1 promoter sequence

Search SABiosciences Chromatin IP Primers for GABRG1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GABRG1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p12 Ensembl cytogenetic band: 4p12 HGNC cytogenetic band: 4p12

GABRG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GABRG1 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04M045953: view genomic region (about GC identifiers)

Start:	46,037,786 bp from pter	End:	46,126,098 bp from pter
Size:	88,313 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GBRG1_HUMAN, Q8N1C3 (See protein sequence)

Recommended Name: Gamma-aminobutyric acid receptor subunit gamma-1 precursor

Size: 465 amino acids; 53595 Da

Subunit: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho

Subcellular location: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane;

Multi-pass membrane protein

Miscellaneous: This subunit carries the benzodiazepine binding site

Secondary accessions: Q5H9T8

Explore the universe of human proteins at neXtProt for GABRG1: NX_Q8N1C3

Post-translational modifications:

May be palmitoylated (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N1C3

GABRG1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_775807.2

ENSEMBL proteins:

ENSP00000295452

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Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0030054	cell junction	IEA	--
GO:0034707	chloride channel complex	IEA	--
GO:0043235	receptor complex	IEA	--
GO:0045211	postsynaptic membrane	IEA	--

GABRG1 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

GABRG1 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR005437 GABBAg_rcpt

IPR018000 Neurotransmitter_ion_chnl_CS

IPR006028 GABAA_rcpt

IPR006201 Neur_channel

IPR005438 GABBAg1_rcpt

Graphical View of Domain Structure for InterPro Entry Q8N1C3

ProtoNet protein and cluster: Q8N1C3

4 Blocks protein families:

IPB005437 Gamma-aminobutyric-acid A receptor gamma subunit signature

IPB005438 Gamma-aminobutyric-acid A receptor gamma 1 subunit signature

IPB006028 Gamma-aminobutyric acid A (GABAA) receptor signature

IPB006201 Neurotransmitter-gated ion-channel

UniProtKB/Swiss-Prot: GBRG1_HUMAN, Q8N1C3

Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5)

subfamily. GABRG1 sub-subfamily

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: GBRG1_HUMAN, Q8N1C3

Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding

to the GABA/benzodiazepine receptor and opening an integral chloride channel

Genatlas biochemistry entry for GABRG1:

gamma-aminobutyric acid (GABA) A receptor,ionotropic,gamma 1,subunit,component of a pentameric receptor mediating

inhibitory neurotransmission

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004890	GABA-A receptor activity	IEA	--
GO:0005230	extracellular ligand-gated ion channel activity	IEA	--
GO:0005254	chloride channel activity	IEA	--
GO:0050811	GABA receptor binding	IEA	--

GABRG1 for ontologies About GeneDecksing

Animal Models:

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GABRG1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Akt Signaling

Akt Signaling

1.00

Apoptosis Pathway

Akt Pathway

0.39

Class A/1 (Rhodopsin-like receptors)

Neuroactive ligand-receptor interaction

0.38

Sweet Taste Signaling

Sperm Motility

0.36

GABA A receptor activation

GABA signaling in brain

0.26

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for GABRG1

GABA signaling in brain

2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GABRG1

	Sperm Motility
	Akt Signaling

1 Tocris Bioscience Pathway for GABRG1

Akt Pathway

1 Kegg Pathway (Kegg details for GABRG1):

Neuroactive ligand-receptor interaction

GABRG1 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for GABRG1

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for GABRG1 (Q8N1C3³ ENSP00000295452⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GABARAP	O95166³, ENSP00000306866⁴	I2D: score=2 STRING: ENSP00000306866

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007214	gamma-aminobutyric acid signaling pathway	IEA	--
GO:0007268	synaptic transmission	IEA	--

GABRG1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Compounds for GABRG1 available from Tocris Bioscience About this table

Compound	Action	CAS #
Muscimol	Potent GABAA agonist	[2763-96-4]
(+)-Bicuculline	Potent GABAA antagonist	[485-49-4]
Indiplon	Subtype-selective GABAA receptor positive allosteric modulator	[325715-02-4]
L-655,708	Selective for alpha5-containing GABAA receptors	[130477-52-0]
SR 95531 hydrobromide	Selective, competitive GABAA receptor antagonist	[104104-50-9]

2 HMDB Compounds for GABRG1 About this table

Compound	Synonyms	CAS #	PubMed Ids
Chlorine	Cl2 (see all 13)	16887-00-6	--
Gamma-Aminobutyric acid	3-Carboxypropylamine (see all 27)	56-12-2	--

10/23 DrugBank Compounds for GABRG1 (see all 23) About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Lorazepam	(+/-)-Lorazepam (see all 3)	846-49-1	target	potentiator	20138190 18384456 11752090
Adinazolam	--	37115-32-5	target	potentiator	6320036 6148400
Chlordiazepoxide	--	58-25-3	target	potentiator	18384456 11752090
Clobazam	--	22316-47-8	target	potentiator	18384456 11752090
Clonazepam	Chlonazepam (see all 2)	1622-61-3	target	potentiator	18384456 11752090
Clorazepate	--	23887-31-2	target	potentiator	18384456 11752090
Clotiazepam	--	33671-46-4	target	potentiator	18604239 18855614
Diazepam	--	439-14-5	target	potentiator	18384456 11752090
Estazolam	--	29975-16-4	target	potentiator	639854 2889803
Flurazepam	--	17617-23-1	target	potentiator	18384456 11752090

Search CenterWatch for drugs/clinical trials and news about GABRG1 / GBRG1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GABRG1 gene:

NM_173536.3

Unigene Cluster for GABRG1:

Gamma-aminobutyric acid (GABA) A receptor, gamma 1

Hs.375051 [show with all ESTs]

Unigene Representative Sequence: BX648937

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000295452(uc003gxb.3)

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Additional cDNA sequence:

AK122845.1 AK124800.1 AK289806.1 AK299884.1 BC031087.1 BX648937.1 CR933628.1

1 DOTS entry:

DT.75165789

18 AceView cDNA sequences:

AK124800 F09193 AK122845 BQ188415 CK299610 NM_173536 BX420702 BC031087

CK005243 AL119089 N92667 BI600401 F11531 BX410065 BX648937 AL119176

T23444 N99613

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GABRG1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

GABRG1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Blood Brain Barrier

Postnatal Endothelial Cells

Blood Brain Barrier, Endothelium

Neural Tube

Telencephalon

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See GABRG1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GABRG1

SOURCE GeneReport for Unigene cluster: Hs.375051

SABiosciences Expression via Pathway-Focused PCR Arrays including GABRG1:

Neurotransmitter Receptors in human mouse rat

GABA & Glutamate in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GABRG1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for GABRG1 gene from 5/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	GABRG1¹	gamma-aminobutyric acid (GABA) A receptor, gamma 1	80.92(n) 89.98(a)		422771 XM_420725.2 XP_420725.2
lizard (Anolis carolinensis)	Reptilia	GABRG1⁶	--	88(a)	1 ↔ 1	5(102816181-102937899)
zebrafish (Danio rerio)	Actinopterygii	LOC556202¹	gamma-aminobutyric acid receptor subunit gamma-1-like	71.84(n) 80.47(a)		556202 XM_678955.4 XP_684047.4
fruit fly (Drosophila melanogaster)	Insecta	CG8916⁶ Grd⁶ (see all 6)	Glycine receptor (see all 6)	23(a) 23(a) (see all 6)	many ↔ many many ↔ many (see all 6)	X(15815988-15818591) 3L(17816433-17832867)
worm (Caenorhabditis elegans)	Secernentea	lgc-37⁶ lgc-52⁶ (see all 19)	Ligand-Gated ion Channel family member (lgc-52) (see all 19)	30(a) 23(a) (see all 19)	1 ↔ many possible ortholog (see all 19)	III(12785053-12793027) IV(15236862-15243643)

ENSEMBL Gene Tree for GABRG1 (if available)
TreeFam Gene Tree for GABRG1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for GABRG1 gene

GABRE² GABRA2² GABRA3² GABRA1² GABRG2² GABRA4² GABRA6² GABRA5²

GABRG3²

18/23 SIMAP similar genes for GABRG1 using alignment to 1 protein entry: GBRG1_HUMAN(see all similar genes):

GABRG2 GABRG3 GABRE GABRA3 GABRA4 GABRA6

GABRA2 GABRA1 GABRA5 GABRP GABRQ GLRA4

GABRB2 GABRD GABRR1 GABRR2 GABRR3 GLRA2

GABRG1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 4 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs193920916^1,2	C	unknown	46125899(-)	`CTCCCC/TTTTTC`	2	P L	mis¹		0	--	--	--	--
rs76374407^1,2		--	46037318(+)	`ACAGGA/GAAGGG`	1	--	ds500¹		0	--	--	--	--
rs140265375^1,2		--	46037580(+)	`ATGCAC/TAAGCT`	1	--	ds500¹		0	--	--	--	--
rs1497564^1,2	C,H	--	46037709(+)	`AACTTC/TAATAC`	1	--	ds500¹		5		NS EA WA	416
rs73241858^1,2	C	--	46037751(+)	`AAGGGA/TTATAG`	1	--	ds500¹		0	--	--	--	--
rs201320025^1,2	C	--	46037953(+)	`AATCAA/CAAGCC`	1	--	ut3¹		0	--	--	--	--
rs185595405^1,2		--	46038055(+)	`TTTAGA/GTAAAT`	1	--	ut3¹		0	--	--	--	--
rs10938423^1,2	C,F,H	--	46038274(+)	`CTACCT/CGCAAT`	1	--	ut3¹ ese³		27		NA NS EA WA CSA	2491
rs189862671^1,2		--	46038535(+)	`CTTATG/TGTGTC`	1	--	ut3¹		0	--	--	--	--
rs182127955^1,2		--	46038645(+)	`GTCTGC/TCACTT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for GABRG1 (46037786 - 46126098 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for GABRG1
4 CNVs: 6262 44162 39362 98702

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

GABRG1 for disorders           About GeneDecksing

OMIM gene information: 137166    OMIM disorders: --

9 diseases for GABRG1:    About MalaCards

anorexia nervosa wolfram syndrome schizoaffective disorder alcohol dependence

bipolar disorder alcoholism alzheimer's disease schizophrenia

neuronitis

1 disease from the University of Copenhagen DISEASES database for GABRG1:

Alcohol dependence

Genetic Association Database (GAD): GABRG1
Human Genome Epidemiology (HuGE) Navigator: GABRG1 (10 documents)

Export disorders for GABRG1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for GABRG1 gene, integrated from 9 sources (see all 39):
(articles sorted by number of sources associating them with GABRG1)

Utopia: connect your pdf to the dynamic
world of online information

Human chromosomal localization of genes encoding the gamma 1 and gamma 2 subunits of the gamma-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome. (PubMed id 1321425)^{1, 3, 9} Wilcox A.S....Sikela J.M. (1992)
Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. (PubMed id 16080114)^{1, 4} Ma D.Q....Pericak-Vance M.A. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4. (PubMed id 17976953)^{1, 9} Ittiwut C....Gelernter J. (2008)
GABRG1 and GABRA2 variation associated with alcohol de pendence in African Americans. (PubMed id 21919924)¹ Ittiwut C....Gelernter J. (2012)
Genetic association of recovery from eating disorders: the role of GABA receptor SNPs. (PubMed id 21750581)¹ Bloss C.S....Kaye W.H. (2011)
Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder. (PubMed id 20583128)¹ Green E.K....Craddock N. (2010)
Atypical behavioural effects of lorazepam: clues to t he design of novel therapies? (PubMed id 20138190)⁷ Giersch A....Vidailhet P. (2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Association study of 182 candidate genes in anorexia nervosa. (PubMed id 20468064)¹ Pinheiro A.P....Woodside D.B. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 2565	HGNC: 4086	AceView: GABRG1	Ensembl:ENSG00000163285	euGenes: HUgn2565
ECgene: GABRG1	Kegg: 2565	H-InvDB: GABRG1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for GABRG1	Pharmacogenomics, SNPs, Pathways
Protein Spotlight	http://web.expasy.org/spotlight/back_issues/sptlt056.shtml

Intellectual Property for GABRG1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for GABRG1 gene:
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GeneCards and IP:
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GABRG1 Gene

gamma-aminobutyric acid (GABA) A receptor, gamma 1

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GABRG1 Gene

gamma-aminobutyric acid (GABA) A receptor, gamma 1

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